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Crosstalk between CD64+MHCII+ macrophages and CD4+ T cells drives joint pathology during chikungunya.
Published in:
EMBO Molecular Medicine, 2024, v. 16, n. 3, p. 641, doi. 10.1038/s44321-024-00028-y
By:
- Lum, Fok-Moon;
- Chan, Yi-Hao;
- Teo, Teck-Hui;
- Becht, Etienne;
- Amrun, Siti Naqiah;
- Teng, Karen WW;
- Hartimath, Siddesh V;
- Yeo, Nicholas KW;
- Yee, Wearn-Xin;
- Ang, Nicholas;
- Torres-Ruesta, Anthony M;
- Fong, Siew-Wai;
- Goggi, Julian L;
- Newell, Evan W;
- Renia, Laurent;
- Carissimo, Guillaume;
- Ng, Lisa FP
Publication type:
Article
Mutating chikungunya virus non‐structural protein produces potent live‐attenuated vaccine candidate.
Published in:
EMBO Molecular Medicine, 2019, v. 11, n. 6, p. 1, doi. 10.15252/emmm.201810092
By:
- Chan, Yi‐Hao;
- Teo, Teck‐Hui;
- Utt, Age;
- Tan, Jeslin JL;
- Amrun, Siti Naqiah;
- Abu Bakar, Farhana;
- Yee, Wearn‐Xin;
- Becht, Etienne;
- Lee, Cheryl Yi‐Pin;
- Lee, Bernett;
- Rajarethinam, Ravisankar;
- Newell, Evan;
- Merits, Andres;
- Carissimo, Guillaume;
- Lum, Fok‐Moon;
- Ng, Lisa FP
Publication type:
Article
Co‐infection with Chikungunya virus alters trafficking of pathogenic CD8+ T cells into the brain and prevents <italic>Plasmodium</italic>‐induced neuropathology.
Published in:
EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 121, doi. 10.15252/emmm.201707885
By:
- Teo, Teck‐Hui;
- Howland, Shanshan W.;
- Claser, Carla;
- Gun, Sin Yee;
- Poh, Chek Meng;
- Lee, Wendy W. L.;
- Lum, Fok‐Moon;
- Ng, Lisa F. P.;
- Rénia, Laurent
Publication type:
Article
Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus-specific neutralizing antibody response.
Published in:
EMBO Molecular Medicine, 2015, v. 7, n. 1, p. 24, doi. 10.15252/emmm.201404459
By:
- Her, Zhisheng;
- Teng, Terk‐Shin;
- Tan, Jeslin JL;
- Teo, Teck‐Hui;
- Kam, Yiu‐Wing;
- Lum, Fok‐Moon;
- Lee, Wendy WL;
- Gabriel, Christelle;
- Melchiotti, Rossella;
- Andiappan, Anand K;
- Lulla, Valeria;
- Lulla, Aleksei;
- Win, Mar K;
- Chow, Angela;
- Biswas, Subhra K;
- Leo, Yee‐Sin;
- Lecuit, Marc;
- Merits, Andres;
- Rénia, Laurent;
- Ng, Lisa FP
Publication type:
Article
Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein.
Published in:
EMBO Molecular Medicine, 2012, v. 4, n. 4, p. 330, doi. 10.1002/emmm.201200213
By:
- Kam, Yiu-Wing;
- Lum, Fok-Moon;
- Teo, Teck-Hui;
- Lee, Wendy W. L.;
- Simarmata, Diane;
- Harjanto, Sumitro;
- Chua, Chong-Long;
- Chan, Yoke-Fun;
- Wee, Jin-Kiat;
- Chow, Angela;
- Lin, Raymond T. P.;
- Leo, Yee-Sin;
- Le Grand, Roger;
- Sam, I-Ching;
- Tong, Joo-Chuan;
- Roques, Pierre;
- Wiesmüller, Karl-Heinz;
- Rénia, Laurent;
- Rötzschke, Olaf;
- Ng, Lisa F. P.
Publication type:
Article
Viperin restricts chikungunya virus replication and pathology.
Published in:
Journal of Clinical Investigation, 2012, v. 122, n. 12, p. 1, doi. 10.1172/JCI63120
By:
- Teng, Terk-Shin;
- Foo, Suan-Sin;
- Simamarta, Diane;
- Lum, Fok-Moon;
- Teo, Teck-Hui;
- Lulla, Aleksei;
- Yeo, Nicholas K.W.;
- Koh, Esther G.L.;
- Chow, Angela;
- Leo, Yee-Sin;
- Merits, Andres;
- Chin, Keh-Chuang;
- Ng, Lisa F.P.
Publication type:
Article
Virus infection drives IL-2 antibody complexes into pro-inflammatory agonists in mice.
Published in:
Scientific Reports, 2016, p. 37603, doi. 10.1038/srep37603
By:
- Lee, Wendy W. L.;
- Teo, Teck-Hui;
- Lum, Fok-Moon;
- Andiappan, Anand K.;
- Amrun, Siti Naqiah;
- Rénia, Laurent;
- Rötzschke, Olaf;
- Ng, Lisa F. P.
Publication type:
Article
Reply to Noret et al.
Published in:
2012
By:
- Her, Zhisheng;
- Lum, Fok-Moon;
- Chow, Angela;
- Leo, Yee-Sin;
- Rénia, Laurent;
- Chiocchia, Gilles;
- Ng, Lisa F. P.
Publication type:
Letter
Longitudinal [18F]FB-IL-2 PET Imaging to Assess the Immunopathogenicity of O'nyong-nyong Virus Infection.
Published in:
Frontiers in Immunology, 2020, v. 11, p. 1, doi. 10.3389/fimmu.2020.00894
By:
- Chan, Yi-Hao;
- Teo, Teck-Hui;
- Torres-Ruesta, Anthony;
- Hartimath, Siddesh V.;
- Chee, Rhonda Sin-Ling;
- Khanapur, Shivashankar;
- Yong, Fui Fong;
- Ramasamy, Boominathan;
- Cheng, Peter;
- Rajarethinam, Ravisankar;
- Robins, Edward G.;
- Goggi, Julian L.;
- Lum, Fok-Moon;
- Carissimo, Guillaume;
- Rénia, Laurent;
- Ng, Lisa F. P.
Publication type:
Article
Paradoxical Effect of Chloroquine Treatment in Enhancing Chikungunya Virus Infection.
Published in:
Viruses (1999-4915), 2018, v. 10, n. 5, p. 268, doi. 10.3390/v10050268
By:
- Roques, Pierre;
- Thiberville, Simon-Djamel;
- Dupuis-Maguiraga, Laurence;
- Lum, Fok-Moon;
- Labadie, Karine;
- Martinon, Frédéric;
- Gras, Gabriel;
- Lebon, Pierre;
- Ng, Lisa F. P.;
- de Lamballerie, Xavier;
- Le Grand, Roger
Publication type:
Article
Zika Virus Infects Human Fetal Brain Microglia and Induces Inflammation.
Published in:
Clinical Infectious Diseases, 2017, v. 64, n. 7, p. 914, doi. 10.1093/cid/ciw878
By:
- Lum, Fok-Moon;
- Low, Donovan K. S.;
- Fan, Yiping;
- Tan, Jeslin J. L.;
- Lee, Bernett;
- Chan, Jerry K. Y.;
- Rénia, Laurent;
- Ginhoux, Florent;
- Ng, Lisa F. P.
Publication type:
Article
Mouse models for Chikungunya virus: deciphering immune mechanisms responsible for disease and pathology.
Published in:
Immunologic Research, 2012, v. 53, n. 1-3, p. 136, doi. 10.1007/s12026-012-8266-x
By:
- Teo, Teck-Hui;
- Lum, Fok-Moon;
- Lee, Wendy;
- Ng, Lisa
Publication type:
Article
Development of Proniosome Gel Formulation for CHIKV Infection.
Published in:
Pharmaceutics, 2024, v. 16, n. 8, p. 994, doi. 10.3390/pharmaceutics16080994
By:
- Altay Benetti, Ayça;
- Thwin, Ma Thinzar;
- Suhaimi, Ahmad;
- Liang, Ryan Sia Tze;
- Ng, Lisa Fong-Poh;
- Lum, Fok-Moon;
- Benetti, Camillo
Publication type:
Article
Type I interferon shapes the quantity and quality of the anti‐Zika virus antibody response.
Published in:
Clinical & Translational Immunology, 2020, v. 9, n. 4, p. 1, doi. 10.1002/cti2.1126
By:
- Lee, Cheryl Yi‐Pin;
- Carissimo, Guillaume;
- Chen, Zheyuan;
- Lum, Fok‐Moon;
- Abu Bakar, Farhana;
- Rajarethinam, Ravisankar;
- Teo, Teck‐Hui;
- Torres‐Ruesta, Anthony;
- Renia, Laurent;
- Ng, Lisa FP
Publication type:
Article
Novel differential linear B‐cell epitopes to identify Zika and dengue virus infections in patients.
Published in:
Clinical & Translational Immunology, 2020, v. 9, n. 2, p. 1, doi. 10.1002/cti2.1118
By:
- Amrun, Siti Naqiah;
- Yee, Wearn‐Xin;
- Abu Bakar, Farhana;
- Lee, Bernett;
- Kam, Yiu‐Wing;
- Lum, Fok‐Moon;
- Tan, Jeslin JL;
- Lim, Vanessa WX;
- Watthanaworawit, Wanitda;
- Ling, Clare;
- Nosten, Francois;
- Renia, Laurent;
- Leo, Yee‐Sin;
- Ng, Lisa FP
Publication type:
Article
Immunological observations and transcriptomic analysis of trimester‐specific full‐term placentas from three Zika virus‐infected women.
Published in:
Clinical & Translational Immunology, 2019, v. 8, n. 11, p. 1, doi. 10.1002/cti2.1082
By:
- Lum, Fok‐Moon;
- Narang, Vipin;
- Hue, Susan;
- Chen, Jie;
- McGovern, Naomi;
- Rajarethinam, Ravisankar;
- Tan, Jeslin JL;
- Amrun, Siti Naqiah;
- Chan, Yi‐Hao;
- Lee, Cheryl YP;
- Chua, Tze‐Kwang;
- Yee, Wearn‐Xin;
- Yeo, Nicholas KW;
- Tan, Thiam‐Chye;
- Liu, Xuan;
- Haldenby, Sam;
- Leo, Yee‐sin;
- Ginhoux, Florent;
- Chan, Jerry KY;
- Hiscox, Julian
Publication type:
Article
Novel differential linear B‐cell epitopes to identify Zika and dengue virus infections in patients.
Published in:
Clinical & Translational Immunology, 2019, v. 8, n. 7, p. N.PAG, doi. 10.1002/cti2.1066
By:
- Amrun, Siti Naqiah;
- Yee, Wearn‐Xin;
- Abu Bakar, Farhana;
- Lee, Bernett;
- Kam, Yiu‐Wing;
- Lum, Fok‐Moon;
- Tan, Jeslin JL;
- Lim, Vanessa WX;
- Watthanaworawit, Wanitda;
- Ling, Clare;
- Nosten, Francois;
- Renia, Laurent;
- Leo, Yee‐Sin;
- Ng, Lisa FP
Publication type:
Article
Plasmodium co-infection protects against chikungunya virus-induced pathologies.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06227-9
By:
- Teo, Teck-Hui;
- Lum, Fok-Moon;
- Ghaffar, Khairunnisa;
- Chan, Yi-Hao;
- Amrun, Siti Naqiah;
- Tan, Jeslin J. L.;
- Lee, Cheryl Y. P.;
- Chua, Tze-Kwang;
- Carissimo, Guillaume;
- Lee, Wendy W. L.;
- Claser, Carla;
- Rajarethinam, Ravisankar;
- Rénia, Laurent;
- Ng, Lisa F. P.
Publication type:
Article
Multimodal assessments of Zika virus immune pathophysiological responses in marmosets.
Published in:
Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-35481-6
By:
- Lum, Fok-Moon;
- Zhang, Wei;
- Lim, Kheng-Choon;
- Malleret, Benoit;
- Teo, Teck-Hui;
- Koh, Jun-Jia;
- Lee, Kuan J.;
- Chua, Tze-Kwang;
- Kam, Yiu-Wing;
- Yee, Wearn-Xin;
- Huen, Isaac;
- Tan, Jeslin J. L.;
- Amrun, Siti Naqiah;
- Prakash KN, Bhanu;
- Cozzone, Patrick J.;
- Renia, Laurent;
- Lee, Philip T. H.;
- Ng, Lisa F. P.
Publication type:
Article
ZIKV-Specific NS1 Epitopes as Serological Markers of Acute Zika Virus Infection.
Published in:
2019
By:
- Kam, Yiu-Wing;
- Leite, Juliana Almeida;
- Amrun, Siti Naqiah;
- Lum, Fok-Moon;
- Yee, Wearn-Xin;
- Bakar, Farhana Abu;
- Eng, Kai Er;
- Lye, David C;
- Leo, Yee-Sin;
- Chong, Chia-Yin;
- Freitas, Andre Ricardo Ribas;
- Milanez, Guilherme Paier;
- Proença-Modena, Jose Luiz;
- Rénia, Laurent;
- Costa, Fabio T M;
- Ng, Lisa F P;
- Network, Zika-Unicamp;
- Zika-Unicamp Network
Publication type:
journal article
Longitudinal Study of Cellular and Systemic Cytokine Signatures to Define the Dynamics of a Balanced Immune Environment During Disease Manifestation in Zika Virus-Infected Patients.
Published in:
2018
By:
- Lum, Fok-Moon;
- Lye, David C B;
- Tan, Jeslin J L;
- Lee, Bernett;
- Chia, Po-Ying;
- Chua, Tze-Kwang;
- Amrun, Siti N;
- Kam, Yiu-Wing;
- Yee, Wearn-Xin;
- Ling, Wei-Ping;
- Lim, Vanessa W X;
- Pang, Vincent J X;
- Lee, Linda K;
- Mok, Esther W H;
- Chong, Chia-Yin;
- Leo, Yee-Sin;
- Ng, Lisa F P
Publication type:
journal article
A Sensitive Method for Detecting Zika Virus Antigen in Patients' Whole-Blood Specimens as an Alternative Diagnostic Approach.
Published in:
2017
By:
- Fok-Moon Lum;
- Cui Lin;
- Susova, Olga Y.;
- Teck-Hui Teo;
- Siew-Wai Fong;
- Tze-Minn Mak;
- Lee, Linda Kay;
- Chia-Yin Chong;
- Lye, David C. B.;
- Lin, Raymond T. P.;
- Merits, Andres;
- Yee-Sin Leo;
- Ng, Lisa F. P.;
- Lum, Fok-Moon;
- Lin, Cui;
- Teo, Teck-Hui;
- Fong, Siew-Wai;
- Mak, Tze-Minn;
- Chong, Chia-Yin;
- Leo, Yee-Sin
Publication type:
journal article

Found: 22

Crosstalk between CD64<sup>+</sup>MHCII<sup>+</sup> macrophages and CD4<sup>+</sup> T cells drives joint pathology during chikungunya.

Mutating chikungunya virus non‐structural protein produces potent live‐attenuated vaccine candidate.

Co‐infection with Chikungunya virus alters trafficking of pathogenic CD8<sup>+</sup> T cells into the brain and prevents <italic>Plasmodium</italic>‐induced neuropathology.

Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus-specific neutralizing antibody response.

Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein.

Viperin restricts chikungunya virus replication and pathology.

Virus infection drives IL-2 antibody complexes into pro-inflammatory agonists in mice.

Reply to Noret et al.

Longitudinal [18F]FB-IL-2 PET Imaging to Assess the Immunopathogenicity of O'nyong-nyong Virus Infection.

Paradoxical Effect of Chloroquine Treatment in Enhancing Chikungunya Virus Infection.

Zika Virus Infects Human Fetal Brain Microglia and Induces Inflammation.

Mouse models for Chikungunya virus: deciphering immune mechanisms responsible for disease and pathology.

Development of Proniosome Gel Formulation for CHIKV Infection.

Type I interferon shapes the quantity and quality of the anti‐Zika virus antibody response.

Novel differential linear B‐cell epitopes to identify Zika and dengue virus infections in patients.

Immunological observations and transcriptomic analysis of trimester‐specific full‐term placentas from three Zika virus‐infected women.

Novel differential linear B‐cell epitopes to identify Zika and dengue virus infections in patients.

Plasmodium co-infection protects against chikungunya virus-induced pathologies.

Multimodal assessments of Zika virus immune pathophysiological responses in marmosets.

ZIKV-Specific NS1 Epitopes as Serological Markers of Acute Zika Virus Infection.

Longitudinal Study of Cellular and Systemic Cytokine Signatures to Define the Dynamics of a Balanced Immune Environment During Disease Manifestation in Zika Virus-Infected Patients.

A Sensitive Method for Detecting Zika Virus Antigen in Patients' Whole-Blood Specimens as an Alternative Diagnostic Approach.