Works by Lujan, Scott A

Results: 22

Low-fidelity DNA synthesis by the L979F mutator derivative of Saccharomyces cerevisiae DNA polymerase ζ.

Published in:

Nucleic Acids Research, 2009, v. 37, n. 11, p. 3774, doi. 10.1093/nar/gkp238

By:

Stone, Jana E.;
Kissling, Grace E.;
Lujan, Scott A.;
Rogozin, Igor B.;
Stith, Carrie M.;
Burgers, Peter M. J.;
Kunkel, Thomas A.

Publication type:

Article

Evidence that processing of ribonucleotides in DNA by topoisomerase 1 is leading-strand specific.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 4, p. 291, doi. 10.1038/nsmb.2989

By:

Williams, Jessica S;
Clausen, Anders R;
Lujan, Scott A;
Marjavaara, Lisette;
Clark, Alan B;
Burgers, Peter M;
Chabes, Andrei;
Kunkel, Thomas A

Publication type:

Article

Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 3, p. 185, doi. 10.1038/nsmb.2957

By:

Clausen, Anders R;
Lujan, Scott A;
Burkholder, Adam B;
Orebaugh, Clinton D;
Williams, Jessica S;
Clausen, Maryam F;
Malc, Ewa P;
Mieczkowski, Piotr A;
Fargo, David C;
Smith, Duncan J;
Kunkel, Thomas A

Publication type:

Article

Evidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03270-4

By:

Garbacz, Marta A.;
Lujan, Scott A.;
Burkholder, Adam B.;
Cox, Phillip B.;
Qiuqin Wu;
Zhi-Xiong Zhou;
Haber, James E.;
Kunkel, Thomas A.

Publication type:

Article

High fidelity DNA ligation prevents single base insertions in the yeast genome.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-53063-1

By:

Williams, Jessica S.;
Lujan, Scott. A.;
Arana, Mercedes E.;
Burkholder, Adam B.;
Tumbale, Percy P.;
Williams, R. Scott;
Kunkel, Thomas A.

Publication type:

Article

Muver, a computational framework for accurately calling accumulated mutations.

Published in:

BMC Genomics, 2018, v. 19, n. 1, p. 1, doi. 10.1186/s12864-018-4753-3

By:

Burkholder, Adam B.;
Lujan, Scott A.;
Lavender, Christopher A.;
Grimm, Sara A.;
Kunkel, Thomas A.;
Fargo, David C.

Publication type:

Article

Stimulation of Chromosomal Rearrangements by Ribonucleotides.

Published in:

Genetics, 2015, v. 201, n. 3, p. 951, doi. 10.1534/genetics.115.181149

By:

Conover, Hailey N.;
Lujan, Scott A.;
Chapman, Mary J.;
Cornelio, Deborah A.;
Sharif, Rabab;
Williams, Jessica S.;
Clark, Alan B.;
Camilo, Francheska;
Kunkel, Thomas A.;
Argueso, Juan Lucas

Publication type:

Article

Roles for DNA polymerase δ in initiating and terminating leading strand DNA replication.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11995-z

By:

Zhou, Zhi-Xiong;
Lujan, Scott A.;
Burkholder, Adam B.;
Garbacz, Marta A.;
Kunkel, Thomas A.

Publication type:

Article

Pif1 family helicases promote mutation avoidance during DNA replication.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 22, p. 12844, doi. 10.1093/nar/gkac1127

By:

Zhou, Zhi-Xiong;
Follonier, Cindy;
Lujan, Scott A;
Burkholder, Adam B;
Zakian, Virginia A;
Kunkel, Thomas A

Publication type:

Article

The fidelity of DNA replication, particularly on GC-rich templates, is reduced by defects of the Fe–S cluster in DNA polymerase δ.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 10, p. 5623, doi. 10.1093/nar/gkab371

By:

Kiktev, Denis A;
Dominska, Margaret;
Zhang, Tony;
Dahl, Joseph;
Stepchenkova, Elena I;
Mieczkowski, Piotr;
Burgers, Peter M;
Lujan, Scott;
Burkholder, Adam;
Kunkel, Thomas A;
Petes, Thomas D

Publication type:

Article

The absence of the catalytic domains of Saccharomyces cerevisiae DNA polymerase ϵ strongly reduces DNA replication fidelity.

Published in:

Nucleic Acids Research, 2019, v. 47, n. 8, p. 3986, doi. 10.1093/nar/gkz048

By:

Garbacz, Marta A;
Cox, Phillip B;
Sharma, Sushma;
Lujan, Scott A;
Chabes, Andrei;
Kunkel, Thomas A

Publication type:

Article

Genome-wide analysis of the specificity and mechanisms of replication infidelity driven by imbalanced dNTP pools.

Published in:

Nucleic Acids Research, 2016, v. 44, n. 4, p. 1669, doi. 10.1093/nar/gkv1298

By:

Watt, Danielle L.;
Buckland, Robert J.;
Lujan, Scott A.;
Kunkel, Thomas A.;
Chabes, Andrei

Publication type:

Article

Differences in genome-wide repeat sequence instability conferred by proofreading and mismatch repair defects.

Published in:

Nucleic Acids Research, 2015, v. 43, n. 8, p. 4067, doi. 10.1093/nar/gkv271

By:

Lujan, Scott A.;
Clark, Alan B.;
Kunkel, Thomas A.

Publication type:

Article

The mechanism and control of DNA transfer by the conjugative relaxase of resistance plasmid pCU1.

Published in:

Nucleic Acids Research, 2010, v. 38, n. 17, p. 5929, doi. 10.1093/nar/gkq303

By:

Nash, Rebekah Potts;
Habibi, Sohrab;
Cheng, Yuan;
Lujan, Scott A.;
Redinbo, Matthew R.

Publication type:

Article

DNA polymerase zeta generates clustered mutations during bypass of endogenous DNA lesions in Saccharomyces cerevisiae.

Published in:

Environmental & Molecular Mutagenesis, 2012, v. 53, n. 9, p. 777, doi. 10.1002/em.21728

By:

Stone, Jana E.;
Lujan, Scott A.;
Kunkel, Thomas A.

Publication type:

Article

Ultrasensitive deletion detection links mitochondrial DNA replication, disease, and aging.

Published in:

Genome Biology, 2020, v. 21, n. 1, p. N.PAG, doi. 10.1186/s13059-020-02138-5

By:

Lujan, Scott A.;
Longley, Matthew J.;
Humble, Margaret H.;
Lavender, Christopher A.;
Burkholder, Adam;
Blakely, Emma L.;
Alston, Charlotte L.;
Gorman, Grainne S.;
Turnbull, Doug M.;
McFarland, Robert;
Taylor, Robert W.;
Kunkel, Thomas A.;
Copeland, William C.

Publication type:

Article

Mismatch Repair Balances Leading and Lagging Strand DNA Replication Fidelity.

Published in:

PLoS Genetics, 2012, v. 8, n. 10, p. 1, doi. 10.1371/journal.pgen.1003016

By:

Lujan, Scott A.;
Williams, Jessica S.;
Pursell, Zachary F.;
Abdulovic-Cui, Amy A.;
Clark, Alan B.;
McElhinny, Stephanie A. Nick;
Kunkel, Thomas A.

Publication type:

Article

Stability across the Whole Nuclear Genome in the Presence and Absence of DNA Mismatch Repair.

Published in:

Cells (2073-4409), 2021, v. 10, n. 5, p. 1224, doi. 10.3390/cells10051224

By:

Lujan, Scott Alexander;
Kunkel, Thomas A.;
Lopez, Bernard S.;
Matic, Ivan

Publication type:

Article

Instability throughout the Saccharomyces cerevisiae genome resulting from Pms1 endonuclease deficiency.

Published in:

Nucleic Acids Research, 2024, v. 52, n. 16, p. 9574, doi. 10.1093/nar/gkae616

By:

Lujan, Scott A;
Garbacz, Marta A;
Liberti, Sascha E;
Burkholder, Adam B;
Kunkel, Thomas A

Publication type:

Article

Opportunities for new studies of nuclear DNA replication enzymology in budding yeast.

Published in:

Current Genetics, 2020, v. 66, n. 2, p. 299, doi. 10.1007/s00294-019-01023-4

By:

Garbacz, Marta A.;
Lujan, Scott A.;
Kunkel, Thomas A.

Publication type:

Article

Ribonucleotide incorporation into DNA during DNA replication and its consequences.

Published in:

2021

By:

Zhou, Zhi-Xiong;
Williams, Jessica S.;
Lujan, Scott A.;
Kunkel, Thomas A.

Publication type:

Literature Review

Eukaryotic genome instability in light of asymmetric DNA replication.

Published in:

Critical Reviews in Biochemistry & Molecular Biology, 2016, v. 51, n. 1, p. 43, doi. 10.3109/10409238.2015.1117055

By:

Lujan, Scott A.;
Williams, Jessica S.;
Kunkel, Thomas A.

Publication type:

Article