Found: 11

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  • (−)-Englerin A is a Potent and Selective Activator of TRPC4 and TRPC5 Calcium Channels.

    Published in:
    Angewandte Chemie International Edition, 2015, v. 54, n. 12, p. 3787, doi. 10.1002/anie.201411511
    By:
    • Ziegler, Slava;
    • Akbulut, Yasemin;
    • Waldmann, Herbert;
    • Gaunt, Hannah J.;
    • Ludlow, Melanie J.;
    • Bruns, Alexander;
    • Vasudev, Naveen S.;
    • Beech, David J.;
    • Amer, Mohamed S.;
    • Muraki, Katsuhiko;
    • Radtke, Lea;
    • Willot, Matthieu;
    • Hahn, Sven;
    • Seitz, Tobias;
    • Christmann, Mathias
    Publication type:
    Article

  • (−)-Englerin A is a Potent and Selective Activator of TRPC4 and TRPC5 Calcium Channels.

    Published in:
    Angewandte Chemie, 2015, v. 127, n. 12, p. 3858, doi. 10.1002/ange.201411511
    By:
    • Akbulut, Yasemin;
    • Gaunt, Hannah J.;
    • Muraki, Katsuhiko;
    • Ludlow, Melanie J.;
    • Amer, Mohamed S.;
    • Bruns, Alexander;
    • Vasudev, Naveen S.;
    • Radtke, Lea;
    • Willot, Matthieu;
    • Hahn, Sven;
    • Seitz, Tobias;
    • Ziegler, Slava;
    • Christmann, Mathias;
    • Beech, David J.;
    • Waldmann, Herbert
    Publication type:
    Article

  • Endocytosis of hERG Is Clathrin-Independent and Involves Arf6.

    Published in:
    PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0085630
    By:
    • Karnik, Rucha;
    • Ludlow, Melanie J.;
    • Abuarab, Nada;
    • Smith, Andrew J.;
    • Hardy, Matthew E. L.;
    • Elliott, David J. S.;
    • Sivaprasadarao, Asipu
    Publication type:
    Article

  • Improved PIEZO1 agonism through 4‐benzoic acid modification of Yoda1.

    Published in:
    British Journal of Pharmacology, 2023, v. 180, n. 16, p. 2039, doi. 10.1111/bph.15996
    By:
    • Parsonage, Gregory;
    • Cuthbertson, Kevin;
    • Endesh, Naima;
    • Murciano, Nicoletta;
    • Hyman, Adam J.;
    • Revill, Charlotte H.;
    • Povstyan, Oleksandr V.;
    • Chuntharpursat‐Bon, Eulashini;
    • Debant, Marjolaine;
    • Ludlow, Melanie J.;
    • Futers, Timothy Simon;
    • Lichtenstein, Laeticia;
    • Kinsella, Jacob A.;
    • Bartoli, Fiona;
    • Rotordam, Maria Giustina;
    • Becker, Nadine;
    • Brüggemann, Andrea;
    • Foster, Richard;
    • Beech, David J.
    Publication type:
    Article

  • Potent, selective, and subunit-dependent activation of TRPC5 channels by a xanthine derivative.

    Published in:
    2019
    By:
    • Minard, Aisling;
    • Bauer, Claudia C.;
    • Chuntharpursat‐Bon, Eulashini;
    • Pickles, Isabelle B.;
    • Wright, David J.;
    • Ludlow, Melanie J.;
    • Burnham, Matthew P.;
    • Warriner, Stuart L.;
    • Beech, David J.;
    • Muraki, Katsuhiko;
    • Bon, Robin S.;
    • Chuntharpursat-Bon, Eulashini
    Publication type:
    journal article

  • Tonantzitlolone is a nanomolar potency activator of transient receptor potential canonical 1/4/5 channels.

    Published in:
    2018
    By:
    • Rubaiy, Hussein N.;
    • Ludlow, Melanie J.;
    • Siems, Karsten;
    • Norman, Katherine;
    • Foster, Richard;
    • Wolf, Dietmar;
    • Beutler, John A.;
    • Beech, David J.
    Publication type:
    journal article

  • Yoda1 analogue (Dooku1) which antagonizes Yoda1-evoked activation of Piezo1 and aortic relaxation.

    Published in:
    2018
    By:
    • Evans, Elizabeth L.;
    • Cuthbertson, Kevin;
    • Endesh, Naima;
    • Rode, Baptiste;
    • Blythe, Nicola M.;
    • Hyman, Adam J.;
    • Hall, Sally J.;
    • Gaunt, Hannah J.;
    • Ludlow, Melanie J.;
    • Foster, Richard;
    • Beech, David J.
    Publication type:
    journal article

  • Piezo1 integration of vascular architecture with physiological force.

    Published in:
    Nature, 2014, v. 515, n. 7526, p. 279, doi. 10.1038/nature13701
    By:
    • Li, Jing;
    • Hou, Bing;
    • Tumova, Sarka;
    • Bruns, Alexander;
    • Ludlow, Melanie J.;
    • Sedo, Alicia;
    • Hyman, Adam J.;
    • McKeown, Lynn;
    • Yuldasheva, Nadira Y.;
    • Majeed, Yasser;
    • Wilson, Lesley A.;
    • Rode, Baptiste;
    • Bailey, Marc A.;
    • Fu, Zhaojun;
    • Carter, Deborah A. L.;
    • Bilton, Jan;
    • Imrie, Helen;
    • Dear, T. Neil;
    • Cubbon, Richard M.;
    • Kearney, Mark T.
    Publication type:
    Article

  • Natural and synthetic flavonoid modulation of TRPC5 channels.

    Published in:
    2016
    By:
    • Naylor, Jacqueline;
    • Minard, Aisling;
    • Gaunt, Hannah J;
    • Amer, Mohamed S;
    • Wilson, Lesley A;
    • Migliore, Marco;
    • Cheung, Sin Y;
    • Rubaiy, Hussein N;
    • Blythe, Nicola M;
    • Musialowski, Katie E;
    • Ludlow, Melanie J;
    • Evans, William D;
    • Green, Ben L;
    • Yang, Hongjun;
    • You, Yun;
    • Li, Jing;
    • Fishwick, Colin W G;
    • Muraki, Katsuhiko;
    • Beech, David J;
    • Bon, Robin S
    Publication type:
    journal article

  • Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance.

    Published in:
    Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00429-3
    By:
    • Rode, Baptiste;
    • Jian Shi;
    • Endesh, Naima;
    • Drinkhill, Mark J.;
    • Webster, Peter J.;
    • Lotteau, Sabine J.;
    • Bailey, Marc A.;
    • Yuldasheva, Nadira Y.;
    • Ludlow, Melanie J.;
    • Cubbon, Richard M.;
    • Jing Li;
    • Futers, T. Simon;
    • Morley, Lara;
    • Gaunt, Hannah J.;
    • Marszalek, Katarzyna;
    • Viswambharan, Hema;
    • Cuthbertson, Kevin;
    • Baxter, Paul D.;
    • Foster, Richard;
    • Sukumar, Piruthivi
    Publication type:
    Article

  • PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing.

    Published in:
    Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-04706-4
    By:
    • Chuntharpursat-Bon, Eulashini;
    • Povstyan, Oleksandr V.;
    • Ludlow, Melanie J.;
    • Carrier, David J.;
    • Debant, Marjolaine;
    • Shi, Jian;
    • Gaunt, Hannah J.;
    • Bauer, Claudia C.;
    • Curd, Alistair;
    • Simon Futers, T.;
    • Baxter, Paul D.;
    • Peckham, Michelle;
    • Muench, Stephen P.;
    • Adamson, Antony;
    • Humphreys, Neil;
    • Tumova, Sarka;
    • Bon, Robin S.;
    • Cubbon, Richard;
    • Lichtenstein, Laeticia;
    • Beech, David J.
    Publication type:
    Article