Works by Luciani, Alessandro

Results: 25

Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39261-3

By:

Berquez, Marine;
Chen, Zhiyong;
Festa, Beatrice Paola;
Krohn, Patrick;
Keller, Svenja Aline;
Parolo, Silvia;
Korzinkin, Mikhail;
Gaponova, Anna;
Laczko, Endre;
Domenici, Enrico;
Devuyst, Olivier;
Luciani, Alessandro

Publication type:

Article

Nebulized Hyaluronan Ameliorates lung inflammation in cystic fibrosis mice.

Published in:

Pediatric Pulmonology, 2013, v. 48, n. 8, p. 761, doi. 10.1002/ppul.22637

By:

Gavina, Manuela;
Luciani, Alessandro;
Villella, Valeria R.;
Esposito, Speranza;
Ferrari, Eleonora;
Bressani, Ilaria;
Casale, Alida;
Bruscia, Emanuela M.;
Maiuri, Luigi;
Raia, Valeria

Publication type:

Article

Editorial: Mitochondria at the nexus of metabolism, aging, and disease.

Published in:

Frontiers in Cell & Developmental Biology, 2024, p. 1, doi. 10.3389/fcell.2023.1356278

By:

Mallilankaraman, Karthik Babu;
Kennedy, Brian K.;
Sorrentino, Vincenzo;
Luciani, Alessandro

Publication type:

Article

Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition.

Published in:

Nature Cell Biology, 2010, v. 12, n. 9, p. 863, doi. 10.1038/ncb2090

By:

Luciani, Alessandro;
Villella, Valeria Rachela;
Esposito, Speranza;
Brunetti-Pierri, Nicola;
Medina, Diego;
Settembre, Carmine;
Gavina, Manuela;
Pulze, Laura;
Giardino, Ida;
Pettoello-Mantovani, Massimo;
D'Apolito, Maria;
Guido, Stefano;
Masliah, Eliezer;
Spencer, Brian;
Quaratino, Sonia;
Raia, Valeria;
Ballabio, Andrea;
Maiuri, Luigi

Publication type:

Article

Impaired autophagy bridges lysosomal storage disease and epithelial dysfunction in the kidney.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02536-7

By:

Festa, Beatrice Paola;
Zhiyong Chen;
Berquez, Marine;
Debaix, Huguette;
Natsuko Tokonami;
Prange, Jenny Ann;
de Hoek, Glenn van;
Alessio, Cremonesi;
Raimondi, Andrea;
Nevo, Nathalie;
Giles, Rachel H.;
Devuyst, Olivier;
Luciani, Alessandro

Publication type:

Article

A pathogenic role for cystic fibrosis transmembrane conductance regulator in celiac disease.

Published in:

EMBO Journal, 2019, v. 38, n. 2, p. N.PAG, doi. 10.15252/embj.2018100101

By:

Villella, Valeria R;
Venerando, Andrea;
Cozza, Giorgio;
Esposito, Speranza;
Ferrari, Eleonora;
Monzani, Romina;
Spinella, Mara C;
Oikonomou, Vasilis;
Renga, Giorgia;
Tosco, Antonella;
Rossin, Federica;
Guido, Stefano;
Silano, Marco;
Garaci, Enrico;
Chao, Yu‐Kai;
Grimm, Christian;
Luciani, Alessandro;
Romani, Luigina;
Piacentini, Mauro;
Raia, Valeria

Publication type:

Article

Multisystem involvement, defective lysosomes and impaired autophagy in a novel rat model of nephropathic cystinosis.

Published in:

Human Molecular Genetics, 2022, v. 31, n. 13, p. 2262, doi. 10.1093/hmg/ddac033

By:

Krohn, Patrick;
Rega, Laura Rita;
Harvent, Marianne;
Festa, Beatrice Paola;
Taranta, Anna;
Luciani, Alessandro;
Dewulf, Joseph;
Cremonesi, Alessio;
Camassei, Francesca Diomedi;
Hanson, James V M;
Gerth-Kahlert, Christina;
Emma, Francesco;
Berquez, Marine;
Devuyst, Olivier

Publication type:

Article

OCRL deficiency impairs endolysosomal function in a humanized mouse model for Lowe syndrome and Dent disease.

Published in:

Human Molecular Genetics, 2019, v. 28, n. 12, p. 1931, doi. 10.1093/hmg/ddy449

By:

Festa, Beatrice Paola;
Berquez, Marine;
Gassama, Alkaly;
Amrein, Irmgard;
Ismail, Hesham M;
Samardzija, Marijana;
Staiano, Leopoldo;
Luciani, Alessandro;
Grimm, Christian;
Nussbaum, Robert L;
Matteis, Maria Antonietta De;
Dorchies, Olivier M;
Scapozza, Leonardo;
Wolfer, David Paul;
Devuyst, Olivier

Publication type:

Article

The lipid A of Burkholderia multivorans C1576 smooth-type lipopolysaccharide and its pro-inflammatory activity in a cystic fibrosis airways model.

Published in:

Innate Immunity, 2010, v. 16, n. 6, p. 354, doi. 10.1177/1753425909347400

By:

Ieranò, Teresa;
Cescutti, Paola;
Leone, Maria Rosaria;
Luciani, Alessandro;
Rizzo, Roberto;
Raia, Valeria;
Lanzetta, Rosa;
Parrilli, Michelangelo;
Maiuri, Luigi;
Silipo, Alba;
Molinaro, Antonio

Publication type:

Article

Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes.

Published in:

2016

By:

Teumer, Alexander;
Tin, Adrienne;
Sorice, Rossella;
Gorski, Mathias;
Nan Cher Yeo;
Chu, Audrey Y.;
Man Li;
Yong Li;
Mijatovic, Vladan;
Yi-An Ko;
Taliun, Daniel;
Luciani, Alessandro;
Ming-Huei Chen;
Qiong Yang;
Foster, Meredith C.;
Olden, Matthias;
Hiraki, Linda T.;
Tayo, Bamidele O.;
Fuchsberger, Christian;
Dieffenbach, Aida Karina

Publication type:

journal article

Mitochondrial disease, mitophagy, and cellular distress in methylmalonic acidemia.

Published in:

2021

By:

Luciani, Alessandro;
Denley, Matthew C. S.;
Govers, Larissa P.;
Sorrentino, Vincenzo;
Froese, D. Sean

Publication type:

Literature Review

Forensic Entomology and the Estimation of the Minimum Time Since Death in Indoor Cases.

Published in:

Journal of Forensic Sciences, 2015, v. 60, n. 2, p. 525, doi. 10.1111/1556-4029.12647

By:

Bugelli, Valentina;
Forni, David;
Bassi, Luciani Alessandro;
Di Paolo, Marco;
Marra, Damiano;
Lenzi, Scilla;
Toni, Chiara;
Giusiani, Mario;
Domenici, Ranieri;
Gherardi, Mirella;
Vanin, Stefano

Publication type:

Article

Dedifferentiation and aberrations of the endolysosomal compartment characterize the early stage of nephropathic cystinosis.

Published in:

Human Molecular Genetics, 2014, v. 23, n. 9, p. 2266, doi. 10.1093/hmg/ddt617

By:

Raggi, Claudia;
Luciani, Alessandro;
Nevo, Nathalie;
Antignac, Corinne;
Terryn, Sara;
Devuyst, Olivier

Publication type:

Article

Author Correction: Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency.

Published in:

2020

By:

Luciani, Alessandro;
Schumann, Anke;
Berquez, Marine;
Chen, Zhiyong;
Nieri, Daniela;
Failli, Mario;
Debaix, Huguette;
Festa, Beatrice Paola;
Tokonami, Natsuko;
Raimondi, Andrea;
Cremonesi, Alessio;
Carrella, Diego;
Forny, Patrick;
Kölker, Stefan;
Camassei, Francesca Diomedi;
Diaz, Francisca;
Moraes, Carlos T.;
Di Bernardo, Diego;
Baumgartner, Matthias R.;
Devuyst, Olivier

Publication type:

Correction Notice

Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-14729-8

By:

Luciani, Alessandro;
Schumann, Anke;
Berquez, Marine;
Chen, Zhiyong;
Nieri, Daniela;
Failli, Mario;
Debaix, Huguette;
Festa, Beatrice Paola;
Tokonami, Natsuko;
Raimondi, Andrea;
Cremonesi, Alessio;
Carrella, Diego;
Forny, Patrick;
Kölker, Stefan;
Diomedi Camassei, Francesca;
Diaz, Francisca;
Moraes, Carlos T.;
Di Bernardo, Diego;
Baumgartner, Matthias R.;
Devuyst, Olivier

Publication type:

Article

Butyrate Attenuates Lipopolysaccharide-Induced Inflammation in Intestinal Cells and Crohn's Mucosa through Modulation of Antioxidant Defense Machinery.

Published in:

PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0032841

By:

Russo, Ilaria;
Luciani, Alessandro;
Cicco, Paola De;
Troncone, Edoardo;
Ciacci, Carolina

Publication type:

Article

Chloride transporters and receptor-mediated endocytosis in the renal proximal tubule.

Published in:

Journal of Physiology, 2015, v. 593, n. 18, p. 4151, doi. 10.1113/JP270087

By:

Devuyst, Olivier;
Luciani, Alessandro

Publication type:

Article

Mitochondrial Distress in Methylmalonic Acidemia: Novel Pathogenic Insights and Therapeutic Perspectives.

Published in:

Cells (2073-4409), 2022, v. 11, n. 19, p. 3179, doi. 10.3390/cells11193179

By:

Keller, Svenja Aline;
Luciani, Alessandro

Publication type:

Article

Defective Cystinosin, Aberrant Autophagy−Endolysosome Pathways, and Storage Disease: Towards Assembling the Puzzle.

Published in:

Cells (2073-4409), 2022, v. 11, n. 3, p. 326, doi. 10.3390/cells11030326

By:

Rega, Laura Rita;
De Leo, Ester;
Nieri, Daniela;
Luciani, Alessandro

Publication type:

Article

The CTNS-MTORC1 axis couples lysosomal cystine to epithelial cell fate decisions and is a targetable pathway in cystinosis.

Published in:

Autophagy, 2024, v. 20, n. 1, p. 202, doi. 10.1080/15548627.2023.2250165

By:

Luciani, Alessandro;
Devuyst, Olivier

Publication type:

Article

Methylmalonyl acidemia: from mitochondrial metabolism to defective mitophagy and disease.

Published in:

Autophagy, 2020, v. 16, n. 6, p. 1159, doi. 10.1080/15548627.2020.1753927

By:

Luciani, Alessandro;
Devuyst, Olivier

Publication type:

Article

Defective autophagy degradation and abnormal tight junction-associated signaling drive epithelial dysfunction in cystinosis.

Published in:

Autophagy, 2018, v. 14, n. 7, p. 1157, doi. 10.1080/15548627.2018.1446625

By:

Luciani, Alessandro;
Festa, Beatrice Paola;
Zhiyong Chen;
Devuyst, Olivier

Publication type:

Article

Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on ΔF508 cystic fibrosis transmembrane conductance regulator.

Published in:

Autophagy, 2012, v. 8, n. 11, p. 1657, doi. 10.4161/auto.21483

By:

Luciani, Alessandro;
Villella, Valeria Rachela;
Esposito, Speranza;
Gavina, Manuela;
Russo, Ilaria;
Silano, Marco;
Guido, Stefano;
Pettoello-Mantovani, Massimo;
Carnuccio, Rosa;
Scholte, Bob;
De Matteis, Antonella;
Maiuri, Maria Chiara;
Raia, Valeria;
Luini, Alberto;
Kroemer, Guido;
Maiuri, Luigi

Publication type:

Article

Cystic fibrosis.

Published in:

Autophagy, 2011, v. 7, n. 1, p. 104, doi. 10.4161/auto.7.1.13987

By:

Luciani, Alessandro;
Villella, Valeria R.;
Esposito, Speranza;
Brunetti-Pierri, Nicola;
Medina, Diego L.;
Settembre, Carmine;
Gavina, Manuela;
Raia, Valeria;
Ballabio, Andrea;
Maiuri, Luigi

Publication type:

Article

In Vitro Gliadin Challenge: Diagnostic Accuracy and Utility for the Difficult Diagnosis of Celiac Disease.

Published in:

American Journal of Gastroenterology (Springer Nature), 2012, v. 107, n. 1, p. 111, doi. 10.1038/ajg.2011.311

By:

Tortora, Raffaella;
Russo, Ilaria;
De Palma, Giovanni D;
Luciani, Alessandro;
Rispo, Antonio;
Zingone, Fabiana;
Iovino, Paola;
Capone, Pietro;
Ciacci, Carolina

Publication type:

Article