Found: 62
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PAH deficient pathology in humanized c.1066-11G>A phenylketonuria mice.
- Published in:
- Human Molecular Genetics, 2024, v. 33, n. 12, p. 1074, doi. 10.1093/hmg/ddae051
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- Publication type:
- Article
Correction to: CK2 alpha prime and alpha-synuclein pathogenic functional interaction mediates synaptic dysregulation in Huntington's disease.
- Published in:
- 2022
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- Publication type:
- Correction Notice
CK2 alpha prime and alpha-synuclein pathogenic functional interaction mediates synaptic dysregulation in Huntington's disease.
- Published in:
- Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01379-8
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- Publication type:
- Article
CK2 alpha prime and alpha-synuclein pathogenic functional interaction mediates synaptic dysregulation in Huntington's disease.
- Published in:
- Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01379-8
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- Publication type:
- Article
CK2 alpha prime and alpha-synuclein pathogenic functional interaction mediates synaptic dysregulation in huntington's disease.
- Published in:
- Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01379-8
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- Publication type:
- Article
A new non-aggregative splicing isoform of human Tau is decreased in Alzheimer's disease.
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- Acta Neuropathologica, 2021, v. 142, n. 1, p. 159, doi. 10.1007/s00401-021-02317-z
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- Publication type:
- Article
Huntington's disease-specific mis-splicing unveils key effector genes and altered splicing factors.
- Published in:
- 2021
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- Publication type:
- journal article
Prion-Associated Neurodegeneration Causes Both Endoplasmic Reticulum Stress and Proteasome Impairment in a Murine Model of Spontaneous Disease.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 1, p. 465, doi. 10.3390/ijms22010465
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- Article
High concordance between hippocampal transcriptome of the mouse intra‐amygdala kainic acid model and human temporal lobe epilepsy.
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- Epilepsia (Series 4), 2020, v. 61, n. 12, p. 2795, doi. 10.1111/epi.16714
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- Publication type:
- Article
P2X7 Receptor Upregulation in Huntington's Disease Brains.
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- Frontiers in Molecular Neuroscience, 2020, v. 13, p. N.PAG, doi. 10.3389/fnmol.2020.567430
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- Publication type:
- Article
Polyadenylation of mRNA as a novel regulatory mechanism of gene expression in temporal lobe epilepsy.
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- 2020
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- Publication type:
- journal article
Pathogenic SREK1 decrease in Huntington's disease lowers TAF1 mimicking X-linked dystonia parkinsonism.
- Published in:
- 2020
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- Publication type:
- journal article
Altered Levels and Isoforms of Tau and Nuclear Membrane Invaginations in Huntington's Disease.
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- Frontiers in Cellular Neuroscience, 2020, v. 13, p. 1, doi. 10.3389/fncel.2019.00574
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- Publication type:
- Article
Differential regulation of Kidins220 isoforms in Huntington's disease.
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- Brain Pathology, 2020, v. 30, n. 1, p. 120, doi. 10.1111/bpa.12761
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- Publication type:
- Article
Pharmacokinetic evaluation of marbofloxacin after intravenous administration at different ages in llama crias, and pharmacokinetic/pharmacodynamic analysis by Monte Carlo simulation.
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- Journal of Veterinary Pharmacology & Therapeutics, 2018, v. 41, n. 6, p. 861, doi. 10.1111/jvp.12698
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- Publication type:
- Article
Bi-directional genetic modulation of GSK-3β exacerbates hippocampal neuropathology in experimental status epilepticus.
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- Cell Death & Disease, 2018, v. 9, n. 10, p. 1, doi. 10.1038/s41419-018-0963-5
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- Publication type:
- Article
The regulation of proteostasis in glial cells by nucleotide receptors is key in acute neuroinflammation.
- Published in:
- FASEB Journal, 2018, v. 32, n. 6, p. 3020, doi. 10.1096/fj.201701064RR
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- Publication type:
- Article
Tau-positive nuclear indentations in P301S tauopathy mice.
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- Brain Pathology, 2017, v. 27, n. 3, p. 314, doi. 10.1111/bpa.12407
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- Publication type:
- Article
MAP2 Splicing is Altered in Huntington's Disease.
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- Brain Pathology, 2017, v. 27, n. 2, p. 181, doi. 10.1111/bpa.12387
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- Publication type:
- Article
Spatiotemporal progression of ubiquitinproteasome system inhibition after status epilepticus suggests protective adaptation against hippocampal injury.
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- Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0163-2
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- Publication type:
- Article
Faulty splicing and cytoskeleton abnormalities in Huntington's disease.
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- Brain Pathology, 2016, v. 26, n. 6, p. 772, doi. 10.1111/bpa.12430
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- Publication type:
- Article
Altered Machinery of Protein Synthesis in Alzheimer's: From the Nucleolus to the Ribosome.
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- Brain Pathology, 2016, v. 26, n. 5, p. 593, doi. 10.1111/bpa.12335
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- Publication type:
- Article
Subcellular Clearance and Accumulation of Huntington Disease Protein: A Mini-Review.
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- Frontiers in Molecular Neuroscience, 2016, p. 1, doi. 10.3389/fnmol.2016.00027
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- Publication type:
- Article
Decreased glycogen synthase kinase-3 levels and activity contribute to Huntington's disease.
- Published in:
- Human Molecular Genetics, 2015, v. 24, n. 17, p. 5040, doi. 10.1093/hmg/ddv224
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- Publication type:
- Article
Ubiquitin-proteasome system involvement in Huntington's disease.
- Published in:
- Frontiers in Molecular Neuroscience, 2014, v. 7, p. 10, doi. 10.3389/fnmol.2014.00077
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- Publication type:
- Article
Huntington's disease is a four-repeat tauopathy with tau nuclear rods.
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- Nature Medicine, 2014, v. 20, n. 8, p. 881, doi. 10.1038/nm.3617
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- Publication type:
- Article
Mice with a naturally occurring DISC1 mutation display a broad spectrum of behaviors associated to psychiatric disorders.
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- Frontiers in Behavioral Neuroscience, 2014, v. 8, p. 1, doi. 10.3389/fnbeh.2014.00253
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- Publication type:
- Article
In vivo inhibition of the mitochondrial H<sup>+</sup>- ATP synthase in neurons promotes metabolic preconditioning.
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- EMBO Journal, 2014, v. 33, n. 7, p. 762, doi. 10.1002/embj.201386392
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- Publication type:
- Article
Overexpression of synphilin-1 promotes clearance of soluble and misfolded alpha-synuclein without restoring the motor phenotype in aged A30P transgenic mice.
- Published in:
- Human Molecular Genetics, 2014, v. 23, n. 3, p. 767, doi. 10.1093/hmg/ddt467
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- Publication type:
- Article
Neuronal Apoptosis and Motor Deficits in Mice with Genetic Inhibition of GSK-3 Are Fas-Dependent.
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- PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0070952
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- Publication type:
- Article
Protective neuronal induction of ATF5 in endoplasmic reticulum stress induced by status epilepticus.
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- Brain: A Journal of Neurology, 2013, v. 136, n. 4, p. 1161, doi. 10.1093/brain/awt044
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- Publication type:
- Article
CHOP regulates the p53–MDM2 axis and is required for neuronal survival after seizures.
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- Brain: A Journal of Neurology, 2013, v. 136, n. 2, p. 577, doi. 10.1093/brain/aws337
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- Publication type:
- Article
CHOP regulates the p53-MDM2 axis and is required for neuronal survival after seizures.
- Published in:
- 2013
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- Publication type:
- journal article
Looking for novel functions of tau.
- Published in:
- Biochemical Society Transactions, 2012, v. 40, n. 4, p. 653, doi. 10.1042/BST20120006
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- Publication type:
- Article
Pharmacokinetic behavior and pharmacokinetic/pharmacodynamic indices of marbofloxacin after intravenous, subcutaneous, and intramuscular administrations in buffalo calves (<10 days old).
- Published in:
- Journal of Veterinary Pharmacology & Therapeutics, 2012, v. 35, n. 3, p. 301, doi. 10.1111/j.1365-2885.2011.01325.x
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- Publication type:
- Article
α-Synuclein accumulates in huntingtin inclusions but forms independent filaments and its deficiency attenuates early phenotype in a mouse model of Huntington's disease.
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- Human Molecular Genetics, 2012, v. 21, n. 3, p. 495, doi. 10.1093/hmg/ddr507
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- Publication type:
- Article
GSK3β overexpression induces neuronal death and a depletion of the neurogenic niches in the dentate gyrus.
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- Hippocampus, 2011, v. 21, n. 8, p. 910, doi. 10.1002/hipo.20805
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- Publication type:
- Article
Striatal-Enriched Protein Tyrosine Phosphatase Expression and Activity in Huntington’s Disease: A STEP in the Resistance to Excitotoxicity.
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- Journal of Neuroscience, 2011, v. 31, n. 22, p. 8150, doi. 10.1523/JNEUROSCI.3446-10.2011
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- Publication type:
- Article
Increased Neurotransmitter Release at the Neuromuscular Junction in a Mouse Model of Polyglutamine Disease.
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- Journal of Neuroscience, 2011, v. 31, n. 3, p. 1106, doi. 10.1523/JNEUROSCI.2011-10.2011
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- Publication type:
- Article
Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington’s disease.
- Published in:
- Brain: A Journal of Neurology, 2011, v. 134, n. 1, p. 119
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- Publication type:
- Article
Centro de Biologia Molecular "Severo Ochoa": A Center for Basic Research into Alzheimer's Disease.
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- Journal of Alzheimer's Disease, 2010, v. 21, n. 2, p. 325, doi. 10.3233/JAD-2010-100912
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- Publication type:
- Article
NFAT/Fas signaling mediates the neuronal apoptosis and motor side effects of GSK-3 inhibition in a mouse model of lithium therapy.
- Published in:
- 2010
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- Publication type:
- journal article
Tau Kinase I Overexpression Induces Dentate Gyrus Degeneration.
- Published in:
- Neurodegenerative Diseases, 2010, v. 7, n. 1-3, p. 13, doi. 10.1159/000283476
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- Publication type:
- Article
Acute Polyglutamine Expression in Inducible Mouse Model Unravels Ubiquitin/Proteasome System Impairment and Permanent Recovery Attributable to Aggregate Formation.
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- Journal of Neuroscience, 2010, v. 30, n. 10, p. 3675, doi. 10.1523/JNEUROSCI.5673-09.2010
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- Publication type:
- Article
Tau contributes to GSK3 induced hippocampal degeneration and learning deficits that are reduced in tau k.o. mice
- Published in:
- 2009
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- Publication type:
- Abstract
Altered P2X<sub>7</sub>-receptor level and function in mouse models of Huntington's disease and therapeutic efficacy of antagonist administration.
- Published in:
- FASEB Journal, 2009, v. 23, n. 6, p. 1893, doi. 10.1096/fj.08-122275
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- Publication type:
- Article
Neuronal apoptosis and reversible motor deficit in dominant-negative GSK-3 conditional transgenic mice.
- Published in:
- EMBO Journal, 2007, v. 26, n. 11, p. 2743, doi. 10.1038/sj.emboj.7601725
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- Publication type:
- Article
Glycogen synthase kinase-3 inhibition is integral to long-term potentiation.
- Published in:
- European Journal of Neuroscience, 2007, v. 25, n. 1, p. 81, doi. 10.1111/j.1460-9568.2006.05245.x
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- Publication type:
- Article
Chronic lithium administration to FTDP-17 tau and GSK-3β overexpressing mice prevents tau hyperphosphorylation and neurofibrillary tangle formation, but pre-formed neurofibrillary tangles do not revert.
- Published in:
- Journal of Neurochemistry, 2006, v. 99, n. 6, p. 1445, doi. 10.1111/j.1471-4159.2006.04139.x
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- Publication type:
- Article
Inhibition of 26S proteasome activity by huntingtin filaments but not inclusion bodies isolated from mouse and human brain.
- Published in:
- Journal of Neurochemistry, 2006, v. 98, n. 5, p. 1585, doi. 10.1111/j.1471-4159.2006.03968.x
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- Publication type:
- Article