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Minimal purification method enables developability assessment of recombinant proteins.
- Published in:
- Biotechnology & Bioengineering, 2024, v. 121, n. 8, p. 2423, doi. 10.1002/bit.28385
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- Publication type:
- Article
CRISPR-Cas9 knockout screen informs efficient reduction of the Komagataella phaffii secretome.
- Published in:
- Microbial Cell Factories, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12934-024-02466-2
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- Publication type:
- Article
Large-Scale Purification and Characterization of Recombinant Receptor-Binding Domain (RBD) of SARS-CoV-2 Spike Protein Expressed in Yeast.
- Published in:
- Vaccines, 2023, v. 11, n. 10, p. 1602, doi. 10.3390/vaccines11101602
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- Publication type:
- Article
Nanoalum Formulations Containing Aluminum Hydroxide and CpG 1018 TM Adjuvants: The Effect on Stability and Immunogenicity of a Recombinant SARS-CoV-2 RBD Antigen.
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- Vaccines, 2023, v. 11, n. 6, p. 1030, doi. 10.3390/vaccines11061030
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- Publication type:
- Article
Liquid biopsy detection of genomic alterations in pediatric brain tumors from cell-free DNA in peripheral blood, CSF, and urine.
- Published in:
- Neuro-Oncology, 2022, v. 24, n. 8, p. 1352, doi. 10.1093/neuonc/noab299
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- Publication type:
- Article
Intranasal vaccination with lipid-conjugated immunogens promotes antigen transmucosal uptake to drive mucosal and systemic immunity.
- Published in:
- Science Translational Medicine, 2022, v. 14, n. 654, p. 1, doi. 10.1126/scitranslmed.abn1413
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- Publication type:
- Article
WAT3R: recovery of T-cell receptor variable regions from 3′ single-cell RNA-sequencing.
- Published in:
- Bioinformatics, 2022, v. 38, n. 14, p. 3645, doi. 10.1093/bioinformatics/btac382
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- Publication type:
- Article
Mitochondrial variant enrichment from high-throughput single-cell RNA sequencing resolves clonal populations.
- Published in:
- Nature Biotechnology, 2022, v. 40, n. 7, p. 1030, doi. 10.1038/s41587-022-01210-8
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- Publication type:
- Article
Identification of Highly Cross-Reactive Mimotopes for a Public T Cell Response in Murine Melanoma.
- Published in:
- Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.886683
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- Publication type:
- Article
Scalable, methanol‐free manufacturing of the SARS‐CoV‐2 receptor‐binding domain in engineered Komagataella phaffii.
- Published in:
- Biotechnology & Bioengineering, 2022, v. 119, n. 2, p. 657, doi. 10.1002/bit.27979
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- Publication type:
- Article
Modular development enables rapid design of media for alternative hosts.
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- Biotechnology & Bioengineering, 2022, v. 119, n. 1, p. 59, doi. 10.1002/bit.27947
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- Publication type:
- Article
Breast tissue regeneration is driven by cell-matrix interactions coordinating multi-lineage stem cell differentiation through DDR1.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27401-6
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- Publication type:
- Article
Diverse antiviral IgG effector activities are predicted by unique biophysical antibody features.
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- Retrovirology, 2021, v. 18, n. 1, p. 1, doi. 10.1186/s12977-021-00579-9
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- Publication type:
- Article
Lack of CD8<sup>+</sup> T cell effector differentiation during priming mediates checkpoint blockade resistance in non–small cell lung cancer.
- Published in:
- Science Immunology, 2021, v. 6, n. 64, p. 1, doi. 10.1126/sciimmunol.abi8800
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- Publication type:
- Article
Development of a platform process for the production and purification of single‐domain antibodies.
- Published in:
- Biotechnology & Bioengineering, 2021, v. 118, n. 9, p. 3348, doi. 10.1002/bit.27724
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- Publication type:
- Article
Rapid optimization of processes for the integrated purification of biopharmaceuticals.
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- Biotechnology & Bioengineering, 2021, v. 118, n. 9, p. 3435, doi. 10.1002/bit.27767
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- Publication type:
- Article
Clonally expanded, GPR15-expressing pathogenic effector T<sub>H</sub>2 cells are associated with eosinophilic esophagitis.
- Published in:
- Science Immunology, 2021, v. 6, n. 62, p. 1, doi. 10.1126/sciimmunol.abi5586
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- Publication type:
- Article
Molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine candidate for rotavirus.
- Published in:
- Microbial Cell Factories, 2021, v. 20, n. 1, p. 1, doi. 10.1186/s12934-021-01583-6
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- Publication type:
- Article
Modeling of copy number variability in Pichia pastoris.
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- Biotechnology & Bioengineering, 2021, v. 118, n. 5, p. 1832, doi. 10.1002/bit.27698
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- Publication type:
- Article
Alternative hosts as the missing link for equitable therapeutic protein production.
- Published in:
- 2021
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- Publication type:
- Letter
Macroscopic modeling of bioreactors for recombinant protein producing Pichia pastoris in defined medium.
- Published in:
- Biotechnology & Bioengineering, 2021, v. 118, n. 3, p. 1199, doi. 10.1002/bit.27643
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- Publication type:
- Article
Comparative genome‐scale analysis of Pichia pastoris variants informs selection of an optimal base strain.
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- Biotechnology & Bioengineering, 2020, v. 117, n. 2, p. 543, doi. 10.1002/bit.27209
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- Publication type:
- Article
A combined screening and in silico strategy for the rapid design of integrated downstream processes for process and product‐related impurity removal.
- Published in:
- Biotechnology & Bioengineering, 2019, v. 116, n. 9, p. 2178, doi. 10.1002/bit.27018
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- Publication type:
- Article
Challenging the workhorse: Comparative analysis of eukaryotic micro‐organisms for expressing monoclonal antibodies.
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- Biotechnology & Bioengineering, 2019, v. 116, n. 6, p. 1449, doi. 10.1002/bit.26951
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- Publication type:
- Article
Correction to: blood handling and leukocyte isolation methods impact the global transcriptome of immune cells.
- Published in:
- 2018
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- Publication type:
- Correction Notice
Cell and fluid sampling microneedle patches for monitoring skin-resident immunity.
- Published in:
- Science Translational Medicine, 2018, v. 10, n. 467, p. 1, doi. 10.1126/scitranslmed.aar2227
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- Publication type:
- Article
Blood handling and leukocyte isolation methods impact the global transcriptome of immune cells.
- Published in:
- BMC Immunology, 2018, v. 19, n. 1, p. N.PAG, doi. 10.1186/s12865-018-0268-6
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- Publication type:
- Article
An impurity characterization based approach for the rapid development of integrated downstream purification processes.
- Published in:
- Biotechnology & Bioengineering, 2018, v. 115, n. 8, p. 2048, doi. 10.1002/bit.26718
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- Publication type:
- Article
Erythrocyte efferocytosis modulates macrophages towards recovery after intracerebral hemorrhage.
- Published in:
- 2018
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- Publication type:
- journal article
Cover Image, Volume 115, Number 1, January 2018.
- Published in:
- 2018
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- Publication type:
- Other
Development of a general defined medium for Pichia pastoris.
- Published in:
- Biotechnology & Bioengineering, 2018, v. 115, n. 1, p. 103, doi. 10.1002/bit.26440
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- Publication type:
- Article
Cover Image, Volume 114, Number 11, November 2017.
- Published in:
- 2017
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- Publication type:
- Other
Reexamining opportunities for therapeutic protein production in eukaryotic microorganisms.
- Published in:
- Biotechnology & Bioengineering, 2017, v. 114, n. 11, p. 2432, doi. 10.1002/bit.26378
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- Publication type:
- Article
A method for learning a sparse classifier in the presence of missing data for high-dimensional biological datasets.
- Published in:
- Bioinformatics, 2017, v. 33, n. 18, p. 2897, doi. 10.1093/bioinformatics/btx224
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- Publication type:
- Article
Longitudinal multiparameter single-cell analysis of macaques immunized with pneumococcal protein-conjugated or unconjugated polysaccharide vaccines reveals distinct antigen specific memory B cell repertoires.
- Published in:
- PLoS ONE, 2017, v. 12, n. 9, p. 1, doi. 10.1371/journal.pone.0183738
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- Publication type:
- Article
Functional differences between PD-1<sup>+</sup> and PD-1<sup>-</sup> CD4<sup>+</sup> effector T cells in healthy donors and patients with glioblastoma multiforme.
- Published in:
- PLoS ONE, 2017, v. 12, n. 9, p. 1, doi. 10.1371/journal.pone.0181538
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- Publication type:
- Article
TGF-β1 modulates microglial phenotype and promotes recovery after intracerebral hemorrhage.
- Published in:
- 2017
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- Publication type:
- journal article
A Size-Selective Intracellular Delivery Platform.
- Published in:
- Small, 2016, v. 12, n. 42, p. 5873, doi. 10.1002/smll.201601155
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- Publication type:
- Article
Single-cell analysis at the threshold.
- Published in:
- Nature Biotechnology, 2016, v. 34, n. 11, p. 1111, doi. 10.1038/nbt.3721
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- Publication type:
- Article
Comparative genomics and transcriptomics of Pichia pastoris.
- Published in:
- BMC Genomics, 2016, v. 17, p. 1, doi. 10.1186/s12864-016-2876-y
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- Publication type:
- Article
Single-Cell Detection of Secreted Aβ and sAPPα from Human IPSC-Derived Neurons and Astrocytes.
- Published in:
- Journal of Neuroscience, 2016, v. 36, n. 5, p. 1730, doi. 10.1523/JNEUROSCI.2735-15.2016
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- Publication type:
- Article
Neutralizing antibodies against West Nile virus identified directly from human B cells by single-cell analysis and next generation sequencing.
- Published in:
- Integrative Biology, 2015, v. 7, n. 12, p. 1587, doi. 10.1039/c5ib00169b
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- Publication type:
- Article
Development of a High-Throughput Functional Screen Using Nanowell-Assisted Cell Patterning.
- Published in:
- Small, 2015, v. 11, n. 36, p. 4643, doi. 10.1002/smll.201500674
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- Publication type:
- Article
Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis.
- Published in:
- Science Translational Medicine, 2015, v. 7, n. 287, p. 1, doi. 10.1126/scitranslmed.aaa8038
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- Publication type:
- Article
Calibrating genomic and allelic coverage bias in single-cell sequencing.
- Published in:
- Nature Communications, 2015, v. 6, n. 4, p. 6822, doi. 10.1038/ncomms7822
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- Publication type:
- Article
Functional analysis of single cells identifies a rare subset of circulating tumor cells with malignant traits.
- Published in:
- Integrative Biology, 2014, v. 6, n. 4, p. 388, doi. 10.1039/c3ib40264a
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- Publication type:
- Article
In vivo discovery of immunotherapy targets in the tumour microenvironment.
- Published in:
- Nature, 2014, v. 506, n. 7486, p. 52, doi. 10.1038/nature12988
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- Publication type:
- Article
Single-cell technologies for monitoring immune systems.
- Published in:
- Nature Immunology, 2014, v. 15, n. 2, p. 128, doi. 10.1038/ni.2796
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- Publication type:
- Article
Single cells from human primary colorectal tumors exhibit polyfunctional heterogeneity in secretions of ELR+ CXC chemokines.
- Published in:
- Integrative Biology, 2013, v. 5, n. 10, p. 1272, doi. 10.1039/c3ib40059j
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- Publication type:
- Article
Single-Cell Analysis Reveals Isotype-Specific Autoreactive B Cell Repertoires in Sjögren’s Syndrome.
- Published in:
- PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0058127
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- Publication type:
- Article