Found: 23

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  • Ultrapotent Broadly Neutralizing Human‐llama Bispecific Antibodies against HIV‐1.

    Published in:
    Advanced Science, 2024, v. 11, n. 26, p. 1, doi. 10.1002/advs.202309268
    By:
    • Xu, Jianliang;
    • Zhou, Tongqing;
    • McKee, Krisha;
    • Zhang, Baoshan;
    • Liu, Cuiping;
    • Nazzari, Alexandra F.;
    • Pegu, Amarendra;
    • Shen, Chen‐Hsiang;
    • Becker, Jordan E.;
    • Bender, Michael F.;
    • Chan, Payton;
    • Changela, Anita;
    • Chaudhary, Ridhi;
    • Chen, Xuejun;
    • Einav, Tal;
    • Kwon, Young Do;
    • Lin, Bob C.;
    • Louder, Mark K.;
    • Merriam, Jonah S.;
    • Morano, Nicholas C.
    Publication type:
    Article

  • Human CD4-binding site antibody elicited by polyvalent DNA prime-protein boost vaccine neutralizes cross-clade tier-2-HIV strains.

    Published in:
    Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-48514-8
    By:
    • Wang, Shixia;
    • Chan, Kun-Wei;
    • Wei, Danlan;
    • Ma, Xiuwen;
    • Liu, Shuying;
    • Hu, Guangnan;
    • Park, Saeyoung;
    • Pan, Ruimin;
    • Gu, Ying;
    • Nazzari, Alexandra F.;
    • Olia, Adam S.;
    • Xu, Kai;
    • Lin, Bob C.;
    • Louder, Mark K.;
    • McKee, Krisha;
    • Doria-Rose, Nicole A.;
    • Montefiori, David;
    • Seaman, Michael S.;
    • Zhou, Tongqing;
    • Kwong, Peter D.
    Publication type:
    Article

  • Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-42098-5
    By:
    • Banach, Bailey B.;
    • Pletnev, Sergei;
    • Olia, Adam S.;
    • Xu, Kai;
    • Zhang, Baoshan;
    • Rawi, Reda;
    • Bylund, Tatsiana;
    • Doria-Rose, Nicole A.;
    • Nguyen, Thuy Duong;
    • Fahad, Ahmed S.;
    • Lee, Myungjin;
    • Lin, Bob C.;
    • Liu, Tracy;
    • Louder, Mark K.;
    • Madan, Bharat;
    • McKee, Krisha;
    • O'Dell, Sijy;
    • Sastry, Mallika;
    • Schön, Arne;
    • Bui, Natalie
    Publication type:
    Article

  • Development of Neutralization Breadth against Diverse HIV‐1 by Increasing Ab–Ag Interface on V2.

    Published in:
    Advanced Science, 2022, v. 9, n. 15, p. 1, doi. 10.1002/advs.202200063
    By:
    • Gao, Nan;
    • Gai, Yanxin;
    • Meng, Lina;
    • Wang, Chu;
    • Wang, Wei;
    • Li, Xiaojun;
    • Gu, Tiejun;
    • Louder, Mark K.;
    • Doria‐Rose, Nicole A.;
    • Wiehe, Kevin;
    • Nazzari, Alexandra F.;
    • Olia, Adam S.;
    • Gorman, Jason;
    • Rawi, Reda;
    • Wu, Wenmin;
    • Smith, Clayton;
    • Khant, Htet;
    • de Val, Natalia;
    • Yu, Bin;
    • Luo, Junhong
    Publication type:
    Article

  • Extended antibody-framework-to-antigen distance observed exclusively with broad HIV-1-neutralizing antibodies recognizing glycan-dense surfaces.

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26579-z
    By:
    • Lee, Myungjin;
    • Changela, Anita;
    • Gorman, Jason;
    • Rawi, Reda;
    • Bylund, Tatsiana;
    • Chao, Cara W.;
    • Lin, Bob C.;
    • Louder, Mark K.;
    • Olia, Adam S.;
    • Zhang, Baoshan;
    • Doria-Rose, Nicole A.;
    • Zolla-Pazner, Susan;
    • Shapiro, Lawrence;
    • Chuang, Gwo-Yu;
    • Kwong, Peter D.
    Publication type:
    Article

  • Improvement of antibody functionality by structure-guided paratope engraftment.

    Published in:
    Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-08658-4
    By:
    • Liu, Qingbo;
    • Lai, Yen-Ting;
    • Zhang, Peng;
    • Louder, Mark K.;
    • Pegu, Amarendra;
    • Rawi, Reda;
    • Asokan, Mangaiarkarasi;
    • Chen, Xuejun;
    • Shen, Chen-Hsiang;
    • Chuang, Gwo-Yu;
    • Yang, Eun Sung;
    • Miao, Huiyi;
    • Wang, Yuge;
    • Fauci, Anthony S.;
    • Kwong, Peter D.;
    • Mascola, John R.;
    • Lusso, Paolo
    Publication type:
    Article

  • Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.

    Published in:
    Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-018-07851-1
    By:
    • Lai, Yen-Ting;
    • Wang, Tao;
    • O'Dell, Sijy;
    • Louder, Mark K.;
    • Schön, Arne;
    • Cheung, Crystal S. F.;
    • Chuang, Gwo-Yu;
    • Druz, Aliaksandr;
    • Lin, Bob;
    • McKee, Krisha;
    • Peng, Dongjun;
    • Yang, Yongping;
    • Zhang, Baoshan;
    • Herschhorn, Alon;
    • Sodroski, Joseph;
    • Bailer, Robert T.;
    • Doria-Rose, Nicole A.;
    • Mascola, John R.;
    • Langley, David R.;
    • Kwong, Peter D.
    Publication type:
    Article

  • Rational design of a trispecific antibody targeting the HIV-1 Env with elevated anti-viral activity.

    Published in:
    Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03335-4
    By:
    • Steinhardt, James J.;
    • Guenaga, Javier;
    • Turner, Hannah L.;
    • McKee, Krisha;
    • Louder, Mark K.;
    • O’Dell, Sijy;
    • Chi-I Chiang;
    • Lin Lei;
    • Galkin, Andrey;
    • Andrianov, Alexander K.;
    • Doria-Rose, Nicole A.;
    • Bailer, Robert T.;
    • Ward, Andrew B.;
    • Mascola, John R.;
    • Yuxing Li
    Publication type:
    Article

  • Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 406, p. 1, doi. 10.1126/scitranslmed.aal1321
    By:
    • Julg, Boris;
    • Tartaglia, Lawrence J.;
    • Keele, Brandon F.;
    • Wagh, Kshitij;
    • Pegu, Amarendra;
    • Sok, Devin;
    • Abbink, Peter;
    • Schmidt, Stephen D.;
    • Keyun Wang;
    • Xuejun Chen;
    • Joyce, M. Gordon;
    • Georgiev, Ivelin S.;
    • Misook Choe;
    • Kwong, Peter D.;
    • Doria-Rose, Nicole A.;
    • Le, Khoa;
    • Louder, Mark K.;
    • Bailer, Robert T.;
    • Moore, Penny L.;
    • Korber, Bette
    Publication type:
    Article

  • Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 381, p. 1, doi. 10.1126/scitranslmed.aai7514
    By:
    • Bonsignori, Mattia;
    • Kreider, Edward F.;
    • Fera, Daniela;
    • Meyerhoff, R. Ryan;
    • Bradley, Todd;
    • Wiehe, Kevin;
    • Alam, S. Munir;
    • Aussedat, Baptiste;
    • Walkowicz, William E.;
    • Kwan-Ki Hwang;
    • Saunders, Kevin O.;
    • Ruijun Zhang;
    • Gladden, Morgan A.;
    • Monroe, Anthony;
    • Kumar, Amit;
    • Shi-Mao Xia;
    • Cooper, Melissa;
    • Louder, Mark K.;
    • McKee, Krisha;
    • Bailer, Robert T.
    Publication type:
    Article

  • Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting.

    Published in:
    PLoS Pathogens, 2017, v. 13, n. 1, p. 1, doi. 10.1371/journal.ppat.1006148
    By:
    • Doria-Rose, Nicole A.;
    • Altae-Tran, Han R.;
    • Roark, Ryan S.;
    • Schmidt, Stephen D.;
    • Sutton, Matthew S.;
    • Louder, Mark K.;
    • Chuang, Gwo-Yu;
    • Bailer, Robert T.;
    • Cortez, Valerie;
    • Kong, Rui;
    • McKee, Krisha;
    • O’Dell, Sijy;
    • Wang, Felicia;
    • Abdool Karim, Salim S.;
    • Binley, James M.;
    • Connors, Mark;
    • Haynes, Barton F.;
    • Martin, Malcolm A.;
    • Montefiori, David C.;
    • Morris, Lynn
    Publication type:
    Article

  • Potent and broad HIV-neutralizing antibodies in memory B cells and plasma.

    Published in:
    Science Immunology, 2017, v. 2, n. 7, p. 1, doi. 10.1126/sciimmunol.aal2200
    By:
    • Williams, LaTonya D.;
    • Ofek, Gilad;
    • Schätzle, Sebastian;
    • McDaniel, Jonathan R.;
    • Xiaozhi Lu;
    • Nicely, Nathan I.;
    • Liming Wu;
    • Lougheed, Caleb S.;
    • Bradley, Todd;
    • Louder, Mark K.;
    • McKee, Krisha;
    • Bailer, Robert T.;
    • O'Dell, Sijy;
    • Georgiev, Ivelin S.;
    • Seaman, Michael S.;
    • Parks, Robert J.;
    • Marshall, Dawn J.;
    • Anasti, Kara;
    • Guang Yang;
    • Xiaoyan Nie
    Publication type:
    Article

  • Optimal Combinations of Broadly Neutralizing Antibodies for Prevention and Treatment of HIV-1 Clade C Infection.

    Published in:
    PLoS Pathogens, 2016, v. 12, n. 3, p. 1, doi. 10.1371/journal.ppat.1005520
    By:
    • Wagh, Kshitij;
    • Bhattacharya, Tanmoy;
    • Williamson, Carolyn;
    • Robles, Alex;
    • Bayne, Madeleine;
    • Garrity, Jetta;
    • Rist, Michael;
    • Rademeyer, Cecilia;
    • Yoon, Hyejin;
    • Lapedes, Alan;
    • Gao, Hongmei;
    • Greene, Kelli;
    • Louder, Mark K.;
    • Kong, Rui;
    • Karim, Salim Abdool;
    • Burton, Dennis R.;
    • Barouch, Dan H.;
    • Nussenzweig, Michel C.;
    • Mascola, John R.;
    • Morris, Lynn
    Publication type:
    Article

  • Structure and immune recognition of trimeric pre-fusion HIV-1 Env.

    Published in:
    Nature, 2014, v. 514, n. 7523, p. 455, doi. 10.1038/nature13808
    By:
    • Pancera, Marie;
    • Zhou, Tongqing;
    • Druz, Aliaksandr;
    • Georgiev, Ivelin S.;
    • Soto, Cinque;
    • Gorman, Jason;
    • Acharya, Priyamvada;
    • Chuang, Gwo-Yu;
    • Ofek, Gilad;
    • Stewart-Jones, Guillaume B. E.;
    • Stuckey, Jonathan;
    • Bailer, Robert T.;
    • Joyce, M. Gordon;
    • Louder, Mark K.;
    • Yang, Yongping;
    • Zhang, Baoshan;
    • Mascola, John R.;
    • Kwong, Peter D.;
    • Huang, Jinghe;
    • Connors, Mark
    Publication type:
    Article

  • Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.

    Published in:
    Nature, 2014, v. 509, n. 7498, p. 55, doi. 10.1038/nature13036
    By:
    • Doria-Rose, Nicole A.;
    • Schramm, Chaim A.;
    • Gorman, Jason;
    • Moore, Penny L.;
    • Bhiman, Jinal N.;
    • DeKosky, Brandon J.;
    • Ernandes, Michael J.;
    • Georgiev, Ivelin S.;
    • Kim, Helen J.;
    • Pancera, Marie;
    • Staupe, Ryan P.;
    • Altae-Tran, Han R.;
    • Bailer, Robert T.;
    • Crooks, Ema T.;
    • Cupo, Albert;
    • Druz, Aliaksandr;
    • Garrett, Nigel J.;
    • Hoi, Kam H.;
    • Kong, Rui;
    • Louder, Mark K.
    Publication type:
    Article

  • Immunological and virological mechanisms of vaccine-mediated protection against SIV and HIV.

    Published in:
    Nature, 2014, v. 505, n. 7484, p. 502, doi. 10.1038/nature12893
    By:
    • Roederer, Mario;
    • Keele, Brandon F.;
    • Schmidt, Stephen D.;
    • Mason, Rosemarie D.;
    • Welles, Hugh C.;
    • Fischer, Will;
    • Labranche, Celia;
    • Foulds, Kathryn E.;
    • Louder, Mark K.;
    • Yang, Zhi-Yong;
    • Todd, John-Paul M.;
    • Buzby, Adam P.;
    • Mach, Linh V.;
    • Shen, Ling;
    • Seaton, Kelly E.;
    • Ward, Brandy M.;
    • Bailer, Robert T.;
    • Gottardo, Raphael;
    • Gu, Wenjuan;
    • Ferrari, Guido
    Publication type:
    Article

  • Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16.

    Published in:
    Nature Structural & Molecular Biology, 2013, v. 20, n. 7, p. 804, doi. 10.1038/nsmb.2600
    By:
    • Pancera, Marie;
    • Shahzad-ul-Hussan, Syed;
    • Doria-Rose, Nicole A;
    • McLellan, Jason S;
    • Bailer, Robert T;
    • Dai, Kaifan;
    • Loesgen, Sandra;
    • Louder, Mark K;
    • Staupe, Ryan P;
    • Yang, Yongping;
    • Zhang, Baoshan;
    • Parks, Robert;
    • Eudailey, Joshua;
    • Lloyd, Krissey E;
    • Blinn, Julie;
    • Alam, S Munir;
    • Haynes, Barton F;
    • Amin, Mohammed N;
    • Wang, Lai-Xi;
    • Burton, Dennis R
    Publication type:
    Article

  • N332-Directed Broadly Neutralizing Antibodies Use Diverse Modes of HIV-1 Recognition: Inferences from Heavy-Light Chain Complementation of Function.

    Published in:
    PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0055701
    By:
    • Pancera, Marie;
    • Yang, Yongping;
    • Louder, Mark K.;
    • Gorman, Jason;
    • Lu, Gabriel;
    • McLellan, Jason S.;
    • Stuckey, Jonathan;
    • Zhu, Jiang;
    • Burton, Dennis R.;
    • Koff, Wayne C.;
    • Mascola, John R.;
    • Kwong, Peter D.
    Publication type:
    Article

  • Broad and potent neutralization of HIV-1 by a gp41-specific human antibody.

    Published in:
    Nature, 2012, v. 491, n. 7424, p. 406, doi. 10.1038/nature11544
    By:
    • Huang, Jinghe;
    • Ofek, Gilad;
    • Laub, Leo;
    • Louder, Mark K.;
    • Doria-Rose, Nicole A.;
    • Longo, Nancy S.;
    • Imamichi, Hiromi;
    • Bailer, Robert T.;
    • Chakrabarti, Bimal;
    • Sharma, Shailendra K.;
    • Alam, S. Munir;
    • Wang, Tao;
    • Yang, Yongping;
    • Zhang, Baoshan;
    • Migueles, Stephen A.;
    • Wyatt, Richard;
    • Haynes, Barton F.;
    • Kwong, Peter D.;
    • Mascola, John R.;
    • Connors, Mark
    Publication type:
    Article

  • Broad HIV-1 neutralization mediated by CD4-binding site antibodies.

    Published in:
    Nature Medicine, 2007, v. 13, n. 9, p. 1032, doi. 10.1038/nm1624
    By:
    • Yuxing Li;
    • Migueles, Stephen A.;
    • Welcher, Brent;
    • Svehla, Krisha;
    • Phogat, Adhuna;
    • Louder, Mark K.;
    • Xueling Wu;
    • Shaw, George M.;
    • Connors, Mark;
    • Wyatt, Richard T.;
    • Mascola, John R.
    Publication type:
    Article

  • The gene product Murr1 restricts HIV-1 replication in resting CD4<sup>+</sup> lymphocytes.

    Published in:
    Nature, 2003, v. 426, n. 6968, p. 853, doi. 10.1038/nature02171
    By:
    • Ganesh, Lakshmanan;
    • Burstein, Ezra;
    • Guha-Niyogi, Anuradha;
    • Louder, Mark K.;
    • Mascola, John R.;
    • Klomp, Leo W.J.;
    • Wijmenga, Cisca;
    • Duckett, Colin S.;
    • Nabel, Gary J.
    Publication type:
    Article

  • Preparation of Clinical-Grade Recombinant Canarypox--Human Immunodeficiency Virus Vaccine--Loaded Human Dendritic Cells.

    Published in:
    Journal of Infectious Diseases, 2002, v. 186, n. 9, p. 1242, doi. 10.1086/344302
    By:
    • Marovich, Mary A.;
    • Mascola, John R.;
    • Eller, Michael A.;
    • Louder, Mark K.;
    • Caudrelier, Pierre A.;
    • El-Habib, Raphaelle;
    • Ratto-Kim, Silvia;
    • Cox, Josephine H.;
    • Currier, Jeffrey R.;
    • Levine, Bruce L.;
    • June, Carl H.;
    • Bernstein, Wendy B.;
    • Robb, Merlin L.;
    • Schuler-Thurner, Beatrice;
    • Steinman, Ralph M.;
    • Birx, Deborah L.;
    • Schlesinger-Frankel, Sarah
    Publication type:
    Article

  • Human skin Langerhans cells are targets of dengue virus infection.

    Published in:
    Nature Medicine, 2000, v. 6, n. 7, p. 816, doi. 10.1038/77553
    By:
    • Wu, Shuenn-Jue L.;
    • Grouard-Vogel, Geraldine;
    • Sun, Wellington;
    • Mascola, John R.;
    • Brachtel, Elena;
    • Putvatana, Ravithat;
    • Louder, Mark K.;
    • Filgueira, Luis;
    • Marovich, Mary A.;
    • Wong, Henry K.;
    • Blauvelt, Andrew;
    • Murphy, Gerald S.;
    • Robb, Merlin L.;
    • Innes, Bruce L.;
    • Birx, Deborah L.;
    • Hayes, Curtis G.;
    • Frankel, Sarah Schlesinger
    Publication type:
    Article