Works by Lorkiewicz, Pawel

Results: 28

Role in Tumor Growth of a Glycogen Debranching Enzyme Lost in Glycogen Storage Disease.
Published in:
JNCI: Journal of the National Cancer Institute, 2014, v. 106, n. 5, p. 1, doi. 10.1093/jnci/dju062
By:
- Guin, Sunny;
- Pollard, Courtney;
- Yuanbin Ru;
- Lew, Carolyn Ritterson;
- Duex, Jason E.;
- Dancik, Garrett;
- Owens, Charles;
- Spencer, Andrea;
- Knight, Scott;
- Holemon, Heather;
- Gupta, Sounak;
- Hansel, Donna;
- Hellerstein, Marc;
- Lorkiewicz, Pawel;
- Lane, Andrew N.;
- Fan, Teresa W.-M.;
- Theodorescu, Dan
Publication type:
Article
Formaldehyde and the transient receptor potential ankyrin-1 contribute to electronic cigarette aerosol-induced endothelial dysfunction in mice.
Published in:
Toxicological Sciences, 2024, v. 201, n. 2, p. 331, doi. 10.1093/toxsci/kfae096
By:
- Jin, Lexiao;
- Richardson, Andre;
- Lynch, Jordan;
- Lorkiewicz, Pawel;
- Srivastava, Shweta;
- Fryar, Laura;
- Miller, Alexis;
- Theis, Whitney;
- Shirk, Gregg;
- Bhatnagar, Aruni;
- Srivastava, Sanjay;
- Riggs, Daniel W;
- Conklin, Daniel J
Publication type:
Article
Biomarkers of Chronic Acrolein Inhalation Exposure in Mice: Implications for Tobacco Product-Induced Toxicity.
Published in:
Toxicological Sciences, 2017, v. 158, n. 2, p. 263, doi. 10.1093/toxsci/kfx095
By:
- Conklin, Daniel J.;
- Malovichko, Marina V.;
- Zeller, Iris;
- Das, Trinath P.;
- Krivokhizhina, Tatiana V.;
- Lynch, Blake H.;
- Lorkiewicz, Pawel;
- Agarwal, Abhinav;
- Wickramasinghe, Nalinie;
- Haberzettl, Petra;
- Sithu, Srinivas D.;
- Shah, Jasmit;
- O'Toole, Timothy E.;
- Rai, Shesh N.;
- Bhatnagar, Aruni;
- Srivastava, Sanjay
Publication type:
Article
Integration of flux measurements and pharmacological controls to optimize stable isotope-resolved metabolomics workflows and interpretation.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-50183-3
By:
- Lorkiewicz, Pawel K.;
- Gibb, Andrew A.;
- Rood, Benjamin R.;
- He, Liqing;
- Zheng, Yuting;
- Clem, Brian F.;
- Zhang, Xiang;
- Hill, Bradford G.
Publication type:
Article
Urinary levels of the acrolein conjugates of carnosine are associated with inhaled toxicants.
Published in:
Inhalation Toxicology, 2020, v. 32, n. 13/14, p. 468, doi. 10.1080/08958378.2020.1845257
By:
- O'Toole, Timothy E.;
- Li, Xiaohong;
- Riggs, Daniel W.;
- Hoetker, David J.;
- Yeager, Ray;
- Lorkiewicz, Pawel;
- Baba, Shahid P.;
- Cooper, Nigel G. F.;
- Bhatnagar, Aruni
Publication type:
Article
Characterization of Volatile Organic Compound Metabolites in Cigarette Smokers, Electronic Nicotine Device Users, Dual Users, and Nonusers of Tobacco.
Published in:
2020
By:
- Keith, Rachel J;
- Fetterman, Jessica L;
- Orimoloye, Olusola A;
- Dardari, Zeina;
- Lorkiewicz, Pawel K;
- Hamburg, Naomi M;
- DeFilippis, Andrew P;
- Blaha, Michael J;
- Bhatnagar, Aruni
Publication type:
journal article
Comparison of Urinary Biomarkers of Exposure in Humans Using Electronic Cigarettes, Combustible Cigarettes, and Smokeless Tobacco.
Published in:
2019
By:
- Lorkiewicz, Pawel;
- Riggs, Daniel W;
- Keith, Rachel J;
- Conklin, Daniel J;
- Xie, Zhengzhi;
- Sutaria, Saurin;
- Lynch, Blake;
- Srivastava, Sanjay;
- Bhatnagar, Aruni
Publication type:
journal article
Nicotine Metabolism in Adults With Type 2 Diabetes.
Published in:
2019
By:
- Keith, Rachel J;
- Riggs, Daniel W;
- Conklin, Daniel J;
- Lorkiewicz, Pawel;
- Srivastava, Sanjay;
- Bhatnagar, Aruni;
- DeFilippis, Andrew P
Publication type:
journal article
Systemic Toxicity of Smokeless Tobacco Products in Mice.
Published in:
2019
By:
- Malovichko, Marina V;
- Zeller, Iris;
- Krivokhizhina, Tatiana V;
- Xie, Zhengzhi;
- Lorkiewicz, Pawel;
- Agarwal, Abhinav;
- Wickramasinghe, Nalinie;
- Sithu, Srinivas D;
- Shah, Jasmit;
- O'Toole, Timothy;
- Rai, Shesh N;
- Bhatnagar, Aruni;
- Conklin, Daniel J;
- Srivastava, Sanjay
Publication type:
journal article
Chemoselective detection and discrimination of carbonyl-containing compounds in metabolite mixtures by <sup>1</sup>H-detected <sup>15</sup>N nuclear magnetic resonance.
Published in:
Magnetic Resonance in Chemistry, 2015, v. 53, n. 5, p. 337, doi. 10.1002/mrc.4199
By:
- Lane, Andrew N.;
- Arumugam, Sengodagounder;
- Lorkiewicz, Pawel K.;
- Higashi, Richard M.;
- Laulhé, Sébastien;
- Nantz, Michael H.;
- Moseley, Hunter N.B.;
- Fan, Teresa W.‐M.
Publication type:
Article
Comparative evaluation of different modalities for measuring in vivo carnosine levels.
Published in:
PLoS ONE, 2024, v. 19, n. 3, p. 1, doi. 10.1371/journal.pone.0299872
By:
- Amraotkar, Alok R.;
- Hoetker, David;
- Negahdar, Mohammad J.;
- Ng, Chin K.;
- Lorkiewicz, Pawel;
- Owolabi, Ugochukwu S.;
- Baba, Shahid P.;
- Bhatnagar, Aruni;
- O'Toole, Timothy E.
Publication type:
Article
Palbociclib treatment alters nucleotide biosynthesis and glutamine dependency in A549 cells.
Published in:
Cancer Cell International, 2020, v. 20, n. 1, p. 1, doi. 10.1186/s12935-020-01357-x
By:
- Conroy, Lindsey R.;
- Lorkiewicz, Pawel;
- He, Liqing;
- Yin, Xinmin;
- Zhang, Xiang;
- Rai, Shesh N.;
- Clem, Brian F.
Publication type:
Article
Cardiac mesenchymal cells from diabetic mice are ineffective for cell therapy-mediated myocardial repair.
Published in:
Basic Research in Cardiology, 2018, v. 113, n. 6, p. 1, doi. 10.1007/s00395-018-0703-0
By:
- Mehra, Parul;
- Guo, Yiru;
- Nong, Yibing;
- Lorkiewicz, Pawel;
- Nasr, Marjan;
- Li, Qianhong;
- Muthusamy, Senthilkumar;
- Bradley, James A.;
- Bhatnagar, Aruni;
- Wysoczynski, Marcin;
- Bolli, Roberto;
- Hill, Bradford G.
Publication type:
Article
Integration of flux measurements to resolve changes in anabolic and catabolic metabolism in cardiac myocytes.
Published in:
Biochemical Journal, 2017, v. 474, n. 16, p. 2785, doi. 10.1042/BCJ20170474
By:
- Gibb, Andrew A.;
- Lorkiewicz, Pawel K.;
- Yu-Ting Zheng;
- Xiang Zhang;
- Bhatnagar, Aruni;
- Jones, Steven P.;
- Hill, Bradford G.
Publication type:
Article
Knockdown of Malic Enzyme 2 Suppresses Lung Tumor Growth, Induces Differentiation and Impacts PI3K/AKT Signaling.
Published in:
Scientific Reports, 2014, p. 1, doi. 10.1038/srep05414
By:
- Jian-Guo Ren;
- Seth, Pankaj;
- Clish, Clary B.;
- Lorkiewicz, Pawel K.;
- Higashi, Richard M.;
- Lane, Andrew N.;
- Fan, Teresa W.-M.;
- Sukhatme, Vikas P.
Publication type:
Article
Metabolic pathways for removing reactive aldehydes are diminished in the skeletal muscle during heart failure.
Published in:
Skeletal Muscle, 2024, v. 14, n. 1, p. 1, doi. 10.1186/s13395-024-00354-2
By:
- Chaudhari, Mamata;
- Zelko, Igor;
- Lorkiewicz, Pawel;
- Hoetker, David;
- Nong, Yibing;
- Doelling, Benjamin;
- Brittian, Kenneth;
- Bhatnagar, Aruni;
- Srivastava, Sanjay;
- Baba, Shahid P.
Publication type:
Article
High information throughput analysis of nucleotides and their isotopically enriched isotopologues by direct-infusion FTICR-MS.
Published in:
Metabolomics, 2012, v. 8, n. 5, p. 930, doi. 10.1007/s11306-011-0388-y
By:
- Lorkiewicz, Pawel;
- Higashi, Richard;
- Lane, Andrew;
- Fan, Teresa
Publication type:
Article
Association Between Residential Greenness and Cardiovascular Disease Risk.
Published in:
2018
By:
- Yeager, Ray;
- Riggs, Daniel W.;
- DeJarnett, Natasha;
- Tollerud, David J.;
- Wilson, Jeffrey;
- Conklin, Daniel J.;
- O'Toole, Timothy E.;
- McCracken, James;
- Lorkiewicz, Pawel;
- Zhengzhi Xie;
- Zafar, Nagma;
- Krishnasamy, Sathya S.;
- Srivastava, Sanjay;
- Finch, Jordan;
- Keith, Rachel J.;
- DeFilippis, Andrew;
- Rai, Shesh N.;
- Liu, Gilbert;
- Bhatnagar, Aruni;
- Xie, Zhengzhi
Publication type:
journal article
Smoking Accelerates Atrioventricular Conduction in Humans Concordant with Increased Dopamine Release.
Published in:
Cardiovascular Toxicology, 2021, v. 21, n. 2, p. 169, doi. 10.1007/s12012-020-09610-5
By:
- Irfan, Affan B.;
- Arab, Claudia;
- DeFilippis, Andrew P.;
- Lorkiewicz, Pawel;
- Keith, Rachel J.;
- Xie, Zhengzhi;
- Bhatnagar, Aruni;
- Carll, Alex P.
Publication type:
Article
Glutamine Regulates Cardiac Progenitor Cell Metabolism and Proliferation.
Published in:
Stem Cells, 2015, v. 33, n. 8, p. 2613, doi. 10.1002/stem.2047
By:
- Hill, Bradford G.;
- Hong, Kyung U.;
- Lorkiewicz, Pawel K.;
- Li, Qianhong;
- Salabei, Joshua K.;
- Holden, Candice R.;
- Bolli, Roberto;
- Bhatnagar, Aruni
Publication type:
Article
Profiling thiol metabolites and quantification of cellular glutathione using FT-ICR-MS spectrometry.
Published in:
Analytical & Bioanalytical Chemistry, 2014, v. 406, n. 18, p. 4371, doi. 10.1007/s00216-014-7810-z
By:
- Gori, Sadakatali;
- Lorkiewicz, Pawel;
- Ehringer, Daniel;
- Belshoff, Alex;
- Higashi, Richard;
- Fan, Teresa;
- Nantz, Michael
Publication type:
Article
Mitochondrial calcium exchange links metabolism with the epigenome to control cellular differentiation.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12103-x
By:
- Lombardi, Alyssa A.;
- Gibb, Andrew A.;
- Arif, Ehtesham;
- Kolmetzky, Devin W.;
- Tomar, Dhanendra;
- Luongo, Timothy S.;
- Jadiya, Pooja;
- Murray, Emma K.;
- Lorkiewicz, Pawel K.;
- Hajnóczky, György;
- Murphy, Elizabeth;
- Arany, Zoltan P.;
- Kelly, Daniel P.;
- Margulies, Kenneth B.;
- Hill, Bradford G.;
- Elrod, John W.
Publication type:
Article
Loss of Rb1 Enhances Glycolytic Metabolism in Kras-Driven Lung Tumors In Vivo.
Published in:
Cancers, 2020, v. 12, n. 1, p. 237, doi. 10.3390/cancers12010237
By:
- Conroy, Lindsey R.;
- Dougherty, Susan;
- Kruer, Traci;
- Metcalf, Stephanie;
- Lorkiewicz, Pawel;
- He, Liqing;
- Yin, Xinmin;
- Zhang, Xiang;
- Arumugam, Sengodagounder;
- Young, Lyndsay E.A.;
- Sun, Ramon C.;
- Clem, Brian F.
Publication type:
Article
Integrated Multilayer Omics Reveals the Genomic, Proteomic, and Metabolic Influences of Histidyl Dipeptides on the Heart.
Published in:
2022
By:
- Keqiang Yan;
- Zhanlong Mei;
- Jingjing Zhao;
- Islam Prodhan, Md Aminul;
- Detlef Obal;
- Katragadda, Kartik;
- Doelling, Benjamin;
- Hoetker, David;
- Posa, Dheeraj Kumar;
- Liqing He;
- Xinmin Yin;
- Shah, Jasmit;
- Jianmin Pan;
- Rai, Shesh;
- Lorkiewicz, Pawel Konrad;
- Xiang Zhang;
- Siqi Liu;
- Bhatnagar, Aruni;
- Baba, Shahid P.;
- Yan, Keqiang
Publication type:
journal article
Stable isotope-resolved metabolomics analyses of metabolic phenotypes reveal variable glutamine metabolism in different patient-derived models of non-small cell lung cancer from a single patient.
Published in:
Metabolomics, 2024, v. 20, n. 4, p. 1, doi. 10.1007/s11306-024-02126-x
By:
- Kinslow, Connor J.;
- ll, Michael Bousamra;
- Cai, Yihua;
- Yan, Jun;
- Lorkiewicz, Pawel K.;
- Al-Attar, Ahmad;
- Tan, Jinlian;
- Higashi, Richard M.;
- Lane, Andrew N.;
- Fan, Teresa W-M.
Publication type:
Article
Differential Inhibition of Anaplerotic Pyruvate Carboxylation and Glutaminolysis-Fueled Anabolism Underlies Distinct Toxicity of Selenium Agents in Human Lung Cancer.
Published in:
Metabolites (2218-1989), 2023, v. 13, n. 7, p. 774, doi. 10.3390/metabo13070774
By:
- Fan, Teresa W.-M.;
- Winnike, Jason;
- Al-Attar, Ahmad;
- Belshoff, Alexander C.;
- Lorkiewicz, Pawel K.;
- Tan, Jin Lian;
- Wu, Min;
- Higashi, Richard M.;
- Lane, Andrew N.
Publication type:
Article
In Vivo Estimation of Ketogenesis Using Metabolic Flux Analysis—Technical Aspects and Model Interpretation.
Published in:
Metabolites (2218-1989), 2021, v. 11, n. 5, p. 279, doi. 10.3390/metabo11050279
By:
- Deja, Stanislaw;
- Kucejova, Blanka;
- Fu, Xiaorong;
- Browning, Jeffrey D.;
- Young, Jamey D.;
- Burgess, Shawn;
- Lorkiewicz, Pawel
Publication type:
Article
Inhalation of printer-emitted particles impairs cardiac conduction, hemodynamics, and autonomic regulation and induces arrhythmia and electrical remodeling in rats.
Published in:
Particle & Fibre Toxicology, 2020, v. 17, n. 1, p. 1, doi. 10.1186/s12989-019-0335-z
By:
- Carll, Alex P.;
- Salatini, Renata;
- Pirela, Sandra V.;
- Wang, Yun;
- Xie, Zhengzhi;
- Lorkiewicz, Pawel;
- Naeem, Nazratan;
- Qian, Yong;
- Castranova, Vincent;
- Godleski, John J.;
- Demokritou, Philip
Publication type:
Article