Works matching AU Lorkiewicz, Pawel

Results: 32

Knockdown of Malic Enzyme 2 Suppresses Lung Tumor Growth, Induces Differentiation and Impacts PI3K/AKT Signaling.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep05414

By:

Jian-Guo Ren;
Seth, Pankaj;
Clish, Clary B.;
Lorkiewicz, Pawel K.;
Higashi, Richard M.;
Lane, Andrew N.;
Fan, Teresa W.-M.;
Sukhatme, Vikas P.

Publication type:

Article

Metabolic pathways for removing reactive aldehydes are diminished in the skeletal muscle during heart failure.

Published in:

Skeletal Muscle, 2024, v. 14, n. 1, p. 1, doi. 10.1186/s13395-024-00354-2

By:

Chaudhari, Mamata;
Zelko, Igor;
Lorkiewicz, Pawel;
Hoetker, David;
Nong, Yibing;
Doelling, Benjamin;
Brittian, Kenneth;
Bhatnagar, Aruni;
Srivastava, Sanjay;
Baba, Shahid P.

Publication type:

Article

Urinary levels of the acrolein conjugates of carnosine are associated with inhaled toxicants.

Published in:

Inhalation Toxicology, 2020, v. 32, n. 13/14, p. 468, doi. 10.1080/08958378.2020.1845257

By:

O'Toole, Timothy E.;
Li, Xiaohong;
Riggs, Daniel W.;
Hoetker, David J.;
Yeager, Ray;
Lorkiewicz, Pawel;
Baba, Shahid P.;
Cooper, Nigel G. F.;
Bhatnagar, Aruni

Publication type:

Article

Characterization of Volatile Organic Compound Metabolites in Cigarette Smokers, Electronic Nicotine Device Users, Dual Users, and Nonusers of Tobacco.

Published in:

2020

By:

Keith, Rachel J;
Fetterman, Jessica L;
Orimoloye, Olusola A;
Dardari, Zeina;
Lorkiewicz, Pawel K;
Hamburg, Naomi M;
DeFilippis, Andrew P;
Blaha, Michael J;
Bhatnagar, Aruni

Publication type:

journal article

Comparison of Urinary Biomarkers of Exposure in Humans Using Electronic Cigarettes, Combustible Cigarettes, and Smokeless Tobacco.

Published in:

2019

By:

Lorkiewicz, Pawel;
Riggs, Daniel W;
Keith, Rachel J;
Conklin, Daniel J;
Xie, Zhengzhi;
Sutaria, Saurin;
Lynch, Blake;
Srivastava, Sanjay;
Bhatnagar, Aruni

Publication type:

journal article

Nicotine Metabolism in Adults With Type 2 Diabetes.

Published in:

2019

By:

Keith, Rachel J;
Riggs, Daniel W;
Conklin, Daniel J;
Lorkiewicz, Pawel;
Srivastava, Sanjay;
Bhatnagar, Aruni;
DeFilippis, Andrew P

Publication type:

journal article

Systemic Toxicity of Smokeless Tobacco Products in Mice.

Published in:

2019

By:

Malovichko, Marina V;
Zeller, Iris;
Krivokhizhina, Tatiana V;
Xie, Zhengzhi;
Lorkiewicz, Pawel;
Agarwal, Abhinav;
Wickramasinghe, Nalinie;
Sithu, Srinivas D;
Shah, Jasmit;
O'Toole, Timothy;
Rai, Shesh N;
Bhatnagar, Aruni;
Conklin, Daniel J;
Srivastava, Sanjay

Publication type:

journal article

Glutamine Regulates Cardiac Progenitor Cell Metabolism and Proliferation.

Published in:

Stem Cells, 2015, v. 33, n. 8, p. 2613, doi. 10.1002/stem.2047

By:

Hill, Bradford G.;
Hong, Kyung U.;
Lorkiewicz, Pawel K.;
Li, Qianhong;
Salabei, Joshua K.;
Holden, Candice R.;
Bolli, Roberto;
Bhatnagar, Aruni

Publication type:

Article

Role of the Transient Receptor Potential Ankyrin-1 in the Pulmonary, Vascular, and Systemic Effects of Short-Term Acrolein Inhalation in Mice: Implications for the Toxicity of Electronic Nicotine Delivery Systems.

Published in:

Cardiovascular Toxicology, 2025, v. 25, n. 4, p. 523, doi. 10.1007/s12012-025-09978-2

By:

Jin, Lexiao;
Richardson, Andre;
Lynch, Jordan;
Miller, Alexis;
Sithu, Israel;
Lorkiewicz, Pawel;
Srivastava, Shweta;
Gao, Hong;
Riggs, Daniel W.;
Srivastava, Sanjay;
Conklin, Daniel J.

Publication type:

Article

Smoking Accelerates Atrioventricular Conduction in Humans Concordant with Increased Dopamine Release.

Published in:

Cardiovascular Toxicology, 2021, v. 21, n. 2, p. 169, doi. 10.1007/s12012-020-09610-5

By:

Irfan, Affan B.;
Arab, Claudia;
DeFilippis, Andrew P.;
Lorkiewicz, Pawel;
Keith, Rachel J.;
Xie, Zhengzhi;
Bhatnagar, Aruni;
Carll, Alex P.

Publication type:

Article

Association Between Residential Greenness and Cardiovascular Disease Risk.

Published in:

2018

By:

Yeager, Ray;
Riggs, Daniel W.;
DeJarnett, Natasha;
Tollerud, David J.;
Wilson, Jeffrey;
Conklin, Daniel J.;
O'Toole, Timothy E.;
McCracken, James;
Lorkiewicz, Pawel;
Zhengzhi Xie;
Zafar, Nagma;
Krishnasamy, Sathya S.;
Srivastava, Sanjay;
Finch, Jordan;
Keith, Rachel J.;
DeFilippis, Andrew;
Rai, Shesh N.;
Liu, Gilbert;
Bhatnagar, Aruni;
Xie, Zhengzhi

Publication type:

journal article

Differential Inhibition of Anaplerotic Pyruvate Carboxylation and Glutaminolysis-Fueled Anabolism Underlies Distinct Toxicity of Selenium Agents in Human Lung Cancer.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 7, p. 774, doi. 10.3390/metabo13070774

By:

Fan, Teresa W.-M.;
Winnike, Jason;
Al-Attar, Ahmad;
Belshoff, Alexander C.;
Lorkiewicz, Pawel K.;
Tan, Jin Lian;
Wu, Min;
Higashi, Richard M.;
Lane, Andrew N.

Publication type:

Article

In Vivo Estimation of Ketogenesis Using Metabolic Flux Analysis—Technical Aspects and Model Interpretation.

Published in:

Metabolites (2218-1989), 2021, v. 11, n. 5, p. 279, doi. 10.3390/metabo11050279

By:

Deja, Stanislaw;
Kucejova, Blanka;
Fu, Xiaorong;
Browning, Jeffrey D.;
Young, Jamey D.;
Burgess, Shawn;
Lorkiewicz, Pawel

Publication type:

Article

Chemoselective detection and discrimination of carbonyl-containing compounds in metabolite mixtures by <sup>1</sup>H-detected <sup>15</sup>N nuclear magnetic resonance.

Published in:

Magnetic Resonance in Chemistry, 2015, v. 53, n. 5, p. 337, doi. 10.1002/mrc.4199

By:

Lane, Andrew N.;
Arumugam, Sengodagounder;
Lorkiewicz, Pawel K.;
Higashi, Richard M.;
Laulhé, Sébastien;
Nantz, Michael H.;
Moseley, Hunter N.B.;
Fan, Teresa W.‐M.

Publication type:

Article

Electronic cigarette-generated aldehydes: The contribution of e-liquid components to their formation and the use of urinary aldehyde metabolites as biomarkers of exposure.

Published in:

Aerosol Science & Technology, 2018, v. 52, n. 11, p. 1219, doi. 10.1080/02786826.2018.1500013

By:

Conklin, Daniel J.;
Ogunwale, Mumiye A.;
Chen, Yizheng;
Theis, Whitney S.;
Nantz, Michael H.;
Fu, Xiao-An;
Chen, Lung-Chi;
Riggs, Daniel W.;
Lorkiewicz, Pawel;
Bhatnagar, Aruni;
Srivastava, Sanjay

Publication type:

Article

Stable isotope-resolved metabolomics analyses of metabolic phenotypes reveal variable glutamine metabolism in different patient-derived models of non-small cell lung cancer from a single patient.

Published in:

Metabolomics, 2024, v. 20, n. 4, p. 1, doi. 10.1007/s11306-024-02126-x

By:

Kinslow, Connor J.;
ll, Michael Bousamra;
Cai, Yihua;
Yan, Jun;
Lorkiewicz, Pawel K.;
Al-Attar, Ahmad;
Tan, Jinlian;
Higashi, Richard M.;
Lane, Andrew N.;
Fan, Teresa W-M.

Publication type:

Article

High information throughput analysis of nucleotides and their isotopically enriched isotopologues by direct-infusion FTICR-MS.

Published in:

Metabolomics, 2012, v. 8, n. 5, p. 930, doi. 10.1007/s11306-011-0388-y

By:

Lorkiewicz, Pawel;
Higashi, Richard;
Lane, Andrew;
Fan, Teresa

Publication type:

Article

Inhalation of printer-emitted particles impairs cardiac conduction, hemodynamics, and autonomic regulation and induces arrhythmia and electrical remodeling in rats.

Published in:

Particle & Fibre Toxicology, 2020, v. 17, n. 1, p. 1, doi. 10.1186/s12989-019-0335-z

By:

Carll, Alex P.;
Salatini, Renata;
Pirela, Sandra V.;
Wang, Yun;
Xie, Zhengzhi;
Lorkiewicz, Pawel;
Naeem, Nazratan;
Qian, Yong;
Castranova, Vincent;
Godleski, John J.;
Demokritou, Philip

Publication type:

Article

Acute and Persistent Cardiovascular Effects of Menthol E-Cigarettes in Mice.

Published in:

Journal of the American Heart Association, 2025, v. 14, n. 9, p. 1, doi. 10.1161/JAHA.124.037420

By:

Ramalingam, Anand R.;
Kucera, Cory;
Srivastava, Shweta;
Paily, Romith;
Stephens, Dawson;
Lorkiewicz, Pawel;
Wilkey, Daniel W.;
Merchant, Michael;
Bhatnagar, Aruni;
Carll, Alex P.

Publication type:

Article

Integrated Multilayer Omics Reveals the Genomic, Proteomic, and Metabolic Influences of Histidyl Dipeptides on the Heart.

Published in:

2022

By:

Keqiang Yan;
Zhanlong Mei;
Jingjing Zhao;
Islam Prodhan, Md Aminul;
Detlef Obal;
Katragadda, Kartik;
Doelling, Benjamin;
Hoetker, David;
Posa, Dheeraj Kumar;
Liqing He;
Xinmin Yin;
Shah, Jasmit;
Jianmin Pan;
Rai, Shesh;
Lorkiewicz, Pawel Konrad;
Xiang Zhang;
Siqi Liu;
Bhatnagar, Aruni;
Baba, Shahid P.;
Yan, Keqiang

Publication type:

journal article

Integration of flux measurements and pharmacological controls to optimize stable isotope-resolved metabolomics workflows and interpretation.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-50183-3

By:

Lorkiewicz, Pawel K.;
Gibb, Andrew A.;
Rood, Benjamin R.;
He, Liqing;
Zheng, Yuting;
Clem, Brian F.;
Zhang, Xiang;
Hill, Bradford G.

Publication type:

Article

Loss of Rb1 Enhances Glycolytic Metabolism in Kras-Driven Lung Tumors In Vivo.

Published in:

Cancers, 2020, v. 12, n. 1, p. 237, doi. 10.3390/cancers12010237

By:

Conroy, Lindsey R.;
Dougherty, Susan;
Kruer, Traci;
Metcalf, Stephanie;
Lorkiewicz, Pawel;
He, Liqing;
Yin, Xinmin;
Zhang, Xiang;
Arumugam, Sengodagounder;
Young, Lyndsay E.A.;
Sun, Ramon C.;
Clem, Brian F.

Publication type:

Article

Biomarkers of Chronic Acrolein Inhalation Exposure in Mice: Implications for Tobacco Product-Induced Toxicity.

Published in:

Toxicological Sciences, 2017, v. 158, n. 2, p. 263, doi. 10.1093/toxsci/kfx095

By:

Conklin, Daniel J.;
Malovichko, Marina V.;
Zeller, Iris;
Das, Trinath P.;
Krivokhizhina, Tatiana V.;
Lynch, Blake H.;
Lorkiewicz, Pawel;
Agarwal, Abhinav;
Wickramasinghe, Nalinie;
Haberzettl, Petra;
Sithu, Srinivas D.;
Shah, Jasmit;
O'Toole, Timothy E.;
Rai, Shesh N.;
Bhatnagar, Aruni;
Srivastava, Sanjay

Publication type:

Article

Cardiac mesenchymal cells from diabetic mice are ineffective for cell therapy-mediated myocardial repair.

Published in:

Basic Research in Cardiology, 2018, v. 113, n. 6, p. 1, doi. 10.1007/s00395-018-0703-0

By:

Mehra, Parul;
Guo, Yiru;
Nong, Yibing;
Lorkiewicz, Pawel;
Nasr, Marjan;
Li, Qianhong;
Muthusamy, Senthilkumar;
Bradley, James A.;
Bhatnagar, Aruni;
Wysoczynski, Marcin;
Bolli, Roberto;
Hill, Bradford G.

Publication type:

Article

Formaldehyde and the transient receptor potential ankyrin-1 contribute to electronic cigarette aerosol-induced endothelial dysfunction in mice.

Published in:

Toxicological Sciences, 2024, v. 201, n. 2, p. 331, doi. 10.1093/toxsci/kfae096

By:

Jin, Lexiao;
Richardson, Andre;
Lynch, Jordan;
Lorkiewicz, Pawel;
Srivastava, Shweta;
Fryar, Laura;
Miller, Alexis;
Theis, Whitney;
Shirk, Gregg;
Bhatnagar, Aruni;
Srivastava, Sanjay;
Riggs, Daniel W;
Conklin, Daniel J

Publication type:

Article

Comparative evaluation of different modalities for measuring in vivo carnosine levels.

Published in:

PLoS ONE, 2024, v. 19, n. 3, p. 1, doi. 10.1371/journal.pone.0299872

By:

Amraotkar, Alok R.;
Hoetker, David;
Negahdar, Mohammad J.;
Ng, Chin K.;
Lorkiewicz, Pawel;
Owolabi, Ugochukwu S.;
Baba, Shahid P.;
Bhatnagar, Aruni;
O'Toole, Timothy E.

Publication type:

Article

Integration of flux measurements to resolve changes in anabolic and catabolic metabolism in cardiac myocytes.

Published in:

Biochemical Journal, 2017, v. 474, n. 16, p. 2785, doi. 10.1042/BCJ20170474

By:

Gibb, Andrew A.;
Lorkiewicz, Pawel K.;
Yu-Ting Zheng;
Xiang Zhang;
Bhatnagar, Aruni;
Jones, Steven P.;
Hill, Bradford G.

Publication type:

Article

Role in Tumor Growth of a Glycogen Debranching Enzyme Lost in Glycogen Storage Disease.

Published in:

JNCI: Journal of the National Cancer Institute, 2014, v. 106, n. 5, p. 1, doi. 10.1093/jnci/dju062

By:

Guin, Sunny;
Pollard, Courtney;
Yuanbin Ru;
Lew, Carolyn Ritterson;
Duex, Jason E.;
Dancik, Garrett;
Owens, Charles;
Spencer, Andrea;
Knight, Scott;
Holemon, Heather;
Gupta, Sounak;
Hansel, Donna;
Hellerstein, Marc;
Lorkiewicz, Pawel;
Lane, Andrew N.;
Fan, Teresa W.-M.;
Theodorescu, Dan

Publication type:

Article

Palbociclib treatment alters nucleotide biosynthesis and glutamine dependency in A549 cells.

Published in:

Cancer Cell International, 2020, v. 20, n. 1, p. 1, doi. 10.1186/s12935-020-01357-x

By:

Conroy, Lindsey R.;
Lorkiewicz, Pawel;
He, Liqing;
Yin, Xinmin;
Zhang, Xiang;
Rai, Shesh N.;
Clem, Brian F.

Publication type:

Article

Profiling thiol metabolites and quantification of cellular glutathione using FT-ICR-MS spectrometry.

Published in:

Analytical & Bioanalytical Chemistry, 2014, v. 406, n. 18, p. 4371, doi. 10.1007/s00216-014-7810-z

By:

Gori, Sadakatali;
Lorkiewicz, Pawel;
Ehringer, Daniel;
Belshoff, Alex;
Higashi, Richard;
Fan, Teresa;
Nantz, Michael

Publication type:

Article

Mitochondrial calcium exchange links metabolism with the epigenome to control cellular differentiation.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12103-x

By:

Lombardi, Alyssa A.;
Gibb, Andrew A.;
Arif, Ehtesham;
Kolmetzky, Devin W.;
Tomar, Dhanendra;
Luongo, Timothy S.;
Jadiya, Pooja;
Murray, Emma K.;
Lorkiewicz, Pawel K.;
Hajnóczky, György;
Murphy, Elizabeth;
Arany, Zoltan P.;
Kelly, Daniel P.;
Margulies, Kenneth B.;
Hill, Bradford G.;
Elrod, John W.

Publication type:

Article

Clustering analysis of volatile organic compound biomarkers with tobacco exposure and the association with cardiovascular health outcomes in an observation study cohort.

Published in:

Tobacco Induced Diseases, 2025, v. 23, p. 1, doi. 10.18332/tid/200649

By:

Zhao, Juan;
Hong, Haoyun;
Zhai, Joseph;
Poudel, Remy;
Srivastava, Sanjay;
Stokes, Andrew C.;
Lorkiewicz, Pawel K.;
Jiang, Tian;
Robertson, Rose Marie;
Bhatnagar, Aruni;
Hall, Jennifer L.;
Hamburg, Naomi M.;
Keith, Rachel J.

Publication type:

Article