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Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs.
- Published in:
- Nature Structural & Molecular Biology, 2014, v. 21, n. 9, p. 803, doi. 10.1038/nsmb.2874
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- Article
Lenalidomide downregulates the cell survival factor, interferon regulatory factor-4, providing a potential mechanistic link for predicting response.
- Published in:
- British Journal of Haematology, 2011, v. 154, n. 3, p. 325, doi. 10.1111/j.1365-2141.2011.08689.x
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- Article
Pomalidomide in combination with dexamethasone results in synergistic anti-tumour responses in pre-clinical models of lenalidomide-resistant multiple myeloma.
- Published in:
- British Journal of Haematology, 2016, v. 172, n. 6, p. 889, doi. 10.1111/bjh.13905
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- Article
Measuring cereblon as a biomarker of response or resistance to lenalidomide and pomalidomide requires use of standardized reagents and understanding of gene complexity.
- Published in:
- British Journal of Haematology, 2014, v. 164, n. 2, p. 233, doi. 10.1111/bjh.12622
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- Article
The surfaceome of multiple myeloma cells suggests potential immunotherapeutic strategies and protein markers of drug resistance.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31810-6
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- Article
Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein.
- Published in:
- Nature, 1999, v. 397, n. 6715, p. 172, doi. 10.1038/16488
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- Article