Works by Longley, Matthew J.

Results: 10

Human DNA polymerase θ possesses 5′-dRP lyase activity and functions in single-nucleotide base excision repair in vitro.

Published in:

Nucleic Acids Research, 2009, v. 37, n. 6, p. 1868, doi. 10.1093/nar/gkp035

By:

Prasad, Rajendra;
Longley, Matthew J.;
Sharief, Farida S.;
Hou, Esther W.;
Copeland, William C.;
Wilson, Samuel H.

Publication type:

Article

Structure-function defects of human mitochondrial DNA polymerase in autosomal dominant progressive external ophthalmoplegia.

Published in:

Nature Structural & Molecular Biology, 2004, v. 11, n. 8, p. 770, doi. 10.1038/nsmb805

By:

Graziewicz, Maria A.;
Longley, Matthew J.;
Bienstock, Rachelle J.;
Zeviani, Massimo;
Copeland, William C.

Publication type:

Article

Characterization of the human homozygous R182W POLG2 mutation in mitochondrial DNA depletion syndrome.

Published in:

PLoS ONE, 2018, v. 13, n. 8, p. 1, doi. 10.1371/journal.pone.0203198

By:

Hoff, Kirsten E.;
DeBalsi, Karen L.;
Sanchez-Quintero, Maria J.;
Longley, Matthew J.;
Hirano, Michio;
Naini, Ali B.;
Copeland, William C.

Publication type:

Article

Single-molecule DREEM imaging reveals DNA wrapping around human mitochondrial single-stranded DNA binding protein.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 21, p. 11287, doi. 10.1093/nar/gky875

By:

Kaur, Parminder;
Longley, Matthew J;
Pan, Hai;
Wang, Hong;
Copeland, William C

Publication type:

Article

Complementation of aprataxin deficiency by base excision repair enzymes in mitochondrial extracts.

Published in:

Nucleic Acids Research, 2017, v. 45, n. 17, p. 10079, doi. 10.1093/nar/gkx654

By:

Çaglayan, Melike;
Prasad, Rajendra;
Krasich, Rachel;
Longley, Matthew J.;
Kei Kadoda;
Masataka Tsuda;
Hiroyuki Sasanuma;
Shunichi Takeda;
Keizo Tano;
Copeland, William C.;
Wilson, Samuel H.

Publication type:

Article

Biochemical analysis of human POLG2 variants associated with mitochondrial disease.

Published in:

Human Molecular Genetics, 2011, v. 20, n. 15, p. 3052, doi. 10.1093/hmg/ddr209

By:

Young, Matthew J.;
Longley, Matthew J.;
Li, Fang-Yuan;
Kasiviswanathan, Rajesh;
Wong, Lee-Jun;
Copeland, William C.

Publication type:

Article

Modulation of the W748S mutation in DNA polymerase γ by the E1143G polymorphismin mitochondrial disorders.

Published in:

Human Molecular Genetics, 2006, v. 15, n. 23, p. 3473, doi. 10.1093/hmg/ddl424

By:

Chan, Sherine S.L.;
Longley, Matthew J.;
Copeland, William C.

Publication type:

Article

Ultrasensitive deletion detection links mitochondrial DNA replication, disease, and aging.

Published in:

Genome Biology, 2020, v. 21, n. 1, p. N.PAG, doi. 10.1186/s13059-020-02138-5

By:

Lujan, Scott A.;
Longley, Matthew J.;
Humble, Margaret H.;
Lavender, Christopher A.;
Burkholder, Adam;
Blakely, Emma L.;
Alston, Charlotte L.;
Gorman, Grainne S.;
Turnbull, Doug M.;
McFarland, Robert;
Taylor, Robert W.;
Kunkel, Thomas A.;
Copeland, William C.

Publication type:

Article

Structure-specific roles for PolG2–DNA complexes in maintenance and replication of mitochondrial DNA.

Published in:

Nucleic Acids Research, 2023, v. 51, n. 18, p. 9716, doi. 10.1093/nar/gkad679

By:

Wojtaszek, Jessica L;
Hoff, Kirsten E;
Longley, Matthew J;
Kaur, Parminder;
Andres, Sara N;
Wang, Hong;
Williams, R Scott;
Copeland, William C

Publication type:

Article

Mitochondrial single-stranded DNA binding protein novel de novo SSBP1 mutation in a child with single large-scale mtDNA deletion (SLSMD) clinically manifesting as Pearson, Kearns-Sayre, and Leigh syndromes.

Published in:

PLoS ONE, 2019, v. 14, n. 9, p. 1, doi. 10.1371/journal.pone.0221829

By:

Gustafson, Margaret A.;
McCormick, Elizabeth M.;
Perera, Lalith;
Longley, Matthew J.;
Bai, Renkui;
Kong, Jianping;
Dulik, Matthew;
Shen, Lishuang;
Goldstein, Amy C.;
McCormack, Shana E.;
Laskin, Benjamin L.;
Leroy, Bart P.;
Ortiz-Gonzalez, Xilma R.;
Ellington, Meredith G.;
Copeland, William C.;
Falk, Marni J.

Publication type:

Article