Works by Long, Yuqing
Results: 18
Exploring the Relationship between Urbanization and Ikization.
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- Sustainability (2071-1050), 2023, v. 15, n. 12, p. 9622, doi. 10.3390/su15129622
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- Article
A Spatially Explicit Optimization Model for Agricultural Straw-Based Power Plant Site Selection: A Case Study in Hubei Province, China.
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- Sustainability (2071-1050), 2017, v. 9, n. 5, p. 832, doi. 10.3390/su9050832
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- Article
HigB of Pseudomon asaeruginosa Enhances Killing of Phagocytes by Up-Regulating the TypeIII Secretion Systemin Ciprofloxacin Induced Persister Cells.
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- Frontiers in Cellular & Infection Microbiology, 2016, v. 6, p. 1, doi. 10.3389/fcimb.2016.00125
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- Article
Unveiling IL6R and MYC as Targeting Biomarkers in Imatinib-Resistant Chronic Myeloid Leukemia through Advanced Non-Invasive Apoptosis Detection Sensor Version 2 Detection.
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- Cells (2073-4409), 2024, v. 13, n. 7, p. 616, doi. 10.3390/cells13070616
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- Article
Development and evaluation of novel recombinant adenovirus-based vaccine candidates for infectious bronchitis virus and Mycoplasma gallisepticum in chickens.
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- Avian Pathology, 2018, v. 47, n. 2, p. 213, doi. 10.1080/03079457.2017.1403009
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- Article
Combination of Azithromycin and Gentamicin for Efficient Treatment of Pseudomonas aeruginosa Infections.
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- 2019
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- journal article
Extracellular Membrane Vesicles of Escherichia coli Induce Apoptosis of CT26 Colon Carcinoma Cells.
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- Microorganisms, 2024, v. 12, n. 7, p. 1446, doi. 10.3390/microorganisms12071446
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- Article
HigB Reciprocally Controls Biofilm Formation and the Expression of Type III Secretion System Genes through Influencing the Intracellular c-di-GMP Level in Pseudomonas aeruginosa.
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- Toxins, 2018, v. 10, n. 11, p. 424, doi. 10.3390/toxins10110424
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- Article
Multifractal scaling analyses of the spatial diffusion pattern of COVID-19 pandemic in Chinese mainland.
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- Humanities & Social Sciences Communications, 2023, v. 10, n. 1, p. 1, doi. 10.1057/s41599-023-02130-x
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- Article
Multifractal scaling analyses of the spatial diffusion pattern of COVID-19 pandemic in Chinese mainland.
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- Humanities & Social Sciences Communications, 2023, v. 10, n. 1, p. 1, doi. 10.1057/s41599-023-02130-x
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- Publication type:
- Article
Colorectal Cancer Cell-Derived Extracellular Vesicles Promote Angiogenesis Through JAK/STAT3/VEGFA Signaling Background: Angiogenesis plays a crucial role in the growth of colorectal cancer (CRC). Recent studies have identified extracellular vesicles (EVs) in the tumor microenvironment as important mediators of cell-to-cell communication. However, the specific role and mechanisms of CRC-derived EVs in regulating tumor angiogenesis remain to be further investigated. Methods: EVs were isolated from the conditioned medium of the CRC cells using ultracentrifugation. We investigated the effects of HT-29-derived EVs on tumor growth and angiogenesis in a subcutaneous HT-29 CRC tumor model in mice. Additionally, we evaluated the impact of HT-29-derived EVs on the proliferation, migration, and tube formation of human umbilical vein endothelial cells (HUVECs). Subsequently, bioinformatics analysis was performed to identify relevant signaling pathways, and pathway inhibitors were used to block the activation of these pathways, aiming to elucidate their roles in angiogenesis. Results: We found that HT-29-derived EVs can promote tumor growth and angiogenesis in vivo, as well as significantly enhance the proliferation, migration, and tube formation of HUVECs. Bioinformatics analysis revealed that HT-29-derived EVs may regulate angiogenesis through the JAK/STAT3 signaling pathway. Specifically, we observed that CRC-derived EVs promoted the phosphorylation of STAT3 (p-STAT3) and the expression of VEGFA in the nucleus of HUVECs. Treatment with the STAT3 inhibitor Stattic reduced the nuclear expression of p-STAT3, which impaired its function as a transcription factor, thereby inhibiting VEGFA expression and the pro-angiogenic effects of CRC-derived EVs. Conclusions: EVs derived from CRC cells promote CRC tumor angiogenesis by regulating VEGFA through the JAK/STAT3 pathway in endothelial cells.
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- Biology (2079-7737), 2024, v. 13, n. 11, p. 873, doi. 10.3390/biology13110873
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- Article
Gravitational scaling analysis on spatial diffusion of COVID-19 in Hubei Province, China.
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- PLoS ONE, 2021, v. 16, n. 6, p. 1, doi. 10.1371/journal.pone.0252889
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- Article
Multifractal scaling analyses of urban street network structure: The cases of twelve megacities in China.
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- PLoS ONE, 2021, v. 16, n. 2, p. 1, doi. 10.1371/journal.pone.0246925
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- Article
Identification of novel genes that promote persister formation by repressing transcription and cell division in Pseudomonas aeruginosa.
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- 2019
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- journal article
Swin Unet3D: a three-dimensional medical image segmentation network combining vision transformer and convolution.
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- BMC Medical Informatics & Decision Making, 2023, v. 23, n. 1, p. 1, doi. 10.1186/s12911-023-02129-z
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- Article
Spatial Signal Analysis Based on Wave-Spectral Fractal Scaling: A Case of Urban Street Networks.
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- Applied Sciences (2076-3417), 2021, v. 11, n. 1, p. 87, doi. 10.3390/app11010087
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- Article
G-cleave LC3B biosensor: monitoring autophagy and assessing resveratrol's synergistic impact on doxorubicin-induced apoptosis in breast cancer cells.
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- Breast Cancer Research, 2024, v. 26, n. 1, p. 1, doi. 10.1186/s13058-024-01951-1
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- Article
Adenovirus-mediated co-expression of the TRAIL and HN genes inhibits growth and induces apoptosis in Marek's disease tumor cell line MSB-1.
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- Cancer Cell International, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12935-015-0172-6
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- Publication type:
- Article