Found: 37
Select item for more details and to access through your institution.
Interconnected lineage trajectories link conventional and natural killer (NK)-like exhausted CD8<sup>+</sup> T cells beneficial in type 1 diabetes.
- Published in:
- Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06456-3
- By:
- Publication type:
- Article
A phase 2 randomized trial with autologous polyclonal expanded regulatory T cells in children with new-onset type 1 diabetes.
- Published in:
- Science Translational Medicine, 2024, v. 16, n. 746, p. 1, doi. 10.1126/scitranslmed.adn2404
- By:
- Publication type:
- Article
A first-in-human, open-label Phase 1b and a randomised, double-blind Phase 2a clinical trial in recent-onset type 1 diabetes with AG019 as monotherapy and in combination with teplizumab.
- Published in:
- Diabetologia, 2024, v. 67, n. 1, p. 27, doi. 10.1007/s00125-023-06014-2
- By:
- Publication type:
- Article
High proinsulin:C-peptide ratio identifies individuals with stage 2 type 1 diabetes at high risk for progression to clinical diagnosis and responses to teplizumab treatment.
- Published in:
- Diabetologia, 2023, v. 66, n. 12, p. 2283, doi. 10.1007/s00125-023-06003-5
- By:
- Publication type:
- Article
Shifts in isoform usage underlie transcriptional differences in regulatory T cells in type 1 diabetes.
- Published in:
- Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-05327-7
- By:
- Publication type:
- Article
Abatacept for Delay of Type 1 Diabetes Progression in Stage 1 Relatives at Risk: A Randomized, Double-Masked, Controlled Trial.
- Published in:
- Diabetes Care, 2023, v. 46, n. 5, p. 1005, doi. 10.2337/dc22-2200
- By:
- Publication type:
- Article
Inflammatory bone marrow signaling in pediatric acute myeloid leukemia distinguishes patients with poor outcomes.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34965-4
- By:
- Publication type:
- Article
Clinical and experimental treatment of type 1 diabetes: Perspectives on immunopathology and Clinical and experimental treatment of type 1 diabetes.
- Published in:
- Clinical & Experimental Immunology, 2022, v. 210, n. 2, p. 105, doi. 10.1093/cei/uxac077
- By:
- Publication type:
- Article
A simple strategy for sample annotation error detection in cytometry datasets.
- Published in:
- Cytometry. Part A, 2022, v. 101, n. 4, p. 351, doi. 10.1002/cyto.a.24525
- By:
- Publication type:
- Article
Guidelines for standardizing T‐cell cytometry assays to link biomarkers, mechanisms, and disease outcomes in type 1 diabetes.
- Published in:
- European Journal of Immunology, 2022, v. 52, n. 3, p. 372, doi. 10.1002/eji.202049067
- By:
- Publication type:
- Article
Deep immune phenotyping reveals similarities between aging, Down syndrome, and autoimmunity.
- Published in:
- Science Translational Medicine, 2022, v. 14, n. 627, p. 1, doi. 10.1126/scitranslmed.abi4888
- By:
- Publication type:
- Article
12-OR: Metabolic Effects of Two Oral Insulin Dosing Regimens in Individuals at High Risk for Type 1 Diabetes (T1D).
- Published in:
- Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-12-OR
- By:
- Publication type:
- Article
Teplizumab improves and stabilizes beta cell function in antibody-positive high-risk individuals.
- Published in:
- Science Translational Medicine, 2021, v. 13, n. 583, p. 1, doi. 10.1126/scitranslmed.abc8980
- By:
- Publication type:
- Article
The COVID-19 immune landscape is dynamically and reversibly correlated with disease severity.
- Published in:
- Journal of Clinical Investigation, 2021, v. 131, n. 3, p. 1, doi. 10.1172/JCI143648
- By:
- Publication type:
- Article
Weekly injection of IL-2 using an injectable hydrogel reduces autoimmune diabetes incidence in NOD mice.
- Published in:
- Diabetologia, 2021, v. 64, n. 1, p. 152, doi. 10.1007/s00125-020-05314-1
- By:
- Publication type:
- Article
A distinct GM-CSF<sup>+</sup> T helper cell subset requires T-bet to adopt a T<sub>H</sub>1 phenotype and promote neuroinflammation.
- Published in:
- Science Immunology, 2020, v. 5, n. 52, p. 1, doi. 10.1126/sciimmunol.aba9953
- By:
- Publication type:
- Article
250-OR: Hypoproliferative CD8 Effector Memory (EM) Subsets Are Linked to Preservation of C-Peptide in Alefacept-Treated Recent-Onset Type 1 Diabetes (T1D) Subjects.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-250-OR
- By:
- Publication type:
- Article
Autoreactive CD8+ T cell exhaustion distinguishes subjects with slow type 1 diabetes progression.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes.
- Published in:
- Diabetes Care, 2020, v. 43, n. 1, p. 5, doi. 10.2337/dc19-0880
- By:
- Publication type:
- Article
Autoreactive CD8<sup>+</sup> T cell exhaustion distinguishes subjects with slow type 1 diabetes progression.
- Published in:
- Journal of Clinical Investigation, 2020, v. 130, n. 1, p. 480, doi. 10.1172/JCI126595
- By:
- Publication type:
- Article
Standardizing T-Cell Biomarkers in Type 1 Diabetes: Challenges and Recent Advances.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Human CD4<sup>+</sup>CD103<sup>+</sup> cutaneous resident memory T cells are found in the circulation of healthy individuals.
- Published in:
- Science Immunology, 2019, v. 4, n. 37, p. 1, doi. 10.1126/sciimmunol.aav8995
- By:
- Publication type:
- Article
1746-P: Differential Depletion and Expansion of Autoreactive CD8+ T Cell Subsets after Alefacept Treatment in Type 1 Diabetes (T1D).
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-1746-P
- By:
- Publication type:
- Article
Dynamic Immune Phenotypes of B and T Helper Cells Mark Distinct Stages of T1D Progression.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Low-Dose Anti-Thymocyte Globulin Preserves C-Peptide, Reduces HbA<sub>1c</sub>, and Increases Regulatory to Conventional T-Cell Ratios in New-Onset Type 1 Diabetes: Two-Year Clinical Trial Data.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Treatment of type 1 diabetes with teplizumab: clinical and immunological follow-up after 7 years from diagnosis.
- Published in:
- Diabetologia, 2019, v. 62, n. 4, p. 655, doi. 10.1007/s00125-018-4786-9
- By:
- Publication type:
- Article
Partial exhaustion of CD8 T cells and clinical response to teplizumab in new-onset type 1 diabetes.
- Published in:
- Science Immunology, 2016, v. 1, n. 5, p. 1, doi. 10.1126/sciimmunol.aai7793
- By:
- Publication type:
- Article
Enhanced T cell responses to IL-6 in type 1 diabetes are associated with early clinical disease and increased IL-6 receptor expression.
- Published in:
- Science Translational Medicine, 2016, v. 8, n. 356, p. 1, doi. 10.1126/scitranslmed.aad9943
- By:
- Publication type:
- Article
Type 1 diabetes immunotherapy using polyclonal regulatory T cells.
- Published in:
- Science Translational Medicine, 2015, v. 7, n. 315, p. 1, doi. 10.1126/scitranslmed.aad4134
- By:
- Publication type:
- Article
Regulatory T Cells Resist Cyclosporine-Induced Cell Death via CD44-Mediated Signaling Pathways.
- Published in:
- International Journal of Cell Biology, 2015, v. 2015, p. 1, doi. 10.1155/2015/614297
- By:
- Publication type:
- Article
Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients.
- Published in:
- Journal of Clinical Investigation, 2015, v. 125, n. 8, p. 3285, doi. 10.1172/JCI81722
- By:
- Publication type:
- Article
Multiple Autoimmune-Associated Variants Confer Decreased IL-2R Signaling in CD4<sup>+</sup>CD25<sup>hi</sup> T Cells of Type 1 Diabetic and Multiple Sclerosis Patients.
- Published in:
- PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0083811
- By:
- Publication type:
- Article
Rapamycin/IL-2 combination therapy in patients with type 1 diabetes augments Tregs yet transiently impairs β-cell function.
- Published in:
- 2012
- By:
- Publication type:
- journal article
Rapamycin/IL-2 Combination Therapy in Patients With Type 1 Diabetes Augments Tregs yet Transiently Impairs β-Cell Function.
- Published in:
- Diabetes, 2012, v. 61, n. 9, p. 2340, doi. 10.2337/db12-0049
- By:
- Publication type:
- Article
Defects in IL-2R signaling contribute to diminished maintenance of FOXP3 expression in CD4(+)CD25(+) regulatory T-cells of type 1 diabetic subjects.
- Published in:
- 2010
- By:
- Publication type:
- journal article
Defects in IL-2R Signaling Contribute to Diminished Maintenance of FOXP3 Expression in CD4<sup>+</sup>CD25<sup>+</sup> Regulatory T-Cells of Type 1 Diabetic Subjects.
- Published in:
- Diabetes, 2010, v. 59, n. 2, p. 407, doi. 10.2337/db09-0694
- By:
- Publication type:
- Article
Functional islet-specific Treg can be generated from CD4.
- Published in:
- European Journal of Immunology, 2009, v. 39, n. 2, p. 612, doi. 10.1002/eji.200838819
- By:
- Publication type:
- Article