Works by Lok, Chun‐Nam

Results: 32

Deubiquitinases as Anticancer Targets of Gold Complexes.

Published in:

Israel Journal of Chemistry, 2016, v. 56, n. 9/10, p. 825, doi. 10.1002/ijch.201600044

By:

Zou, Taotao;
Zhang, Jing‐Jing;
Cao, Bei;
Tong, Ka‐Chung;
Lok, Chun‐Nam;
Che, Chi‐Ming

Publication type:

Article

An Antitumor Bis(N‐Heterocyclic Carbene)Platinum(II) Complex That Engages Asparagine Synthetase as an Anticancer Target.

Published in:

Angewandte Chemie International Edition, 2019, v. 58, n. 32, p. 10914, doi. 10.1002/anie.201904131

By:

Hu, Di;
Yang, Chen;
Lok, Chun‐Nam;
Xing, Fangrong;
Lee, Pui‐Yan;
Fung, Yi Man Eva;
Jiang, Haibo;
Che, Chi‐Ming

Publication type:

Article

Cyclometalated Gold(III) Complexes Containing N-Heterocyclic Carbene Ligands Engage Multiple Anti-Cancer Molecular Targets.

Published in:

Angewandte Chemie International Edition, 2017, v. 56, n. 14, p. 3892, doi. 10.1002/anie.201612583

By:

Fung, Sin Ki;
Zou, Taotao;
Cao, Bei;
Lee, Pui-Yan;
Fung, Yi Man Eva;
Hu, Di;
Lok, Chun-Nam;
Che, Chi-Ming

Publication type:

Article

A Macrocyclic Ruthenium(III) Complex Inhibits Angiogenesis with Down-Regulation of Vascular Endothelial Growth Factor Receptor-2 and Suppresses Tumor Growth In Vivo.

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 43, p. 13524, doi. 10.1002/anie.201608094

By:

Kwong, Wai‐Lun;
Lam, Kar‐Yee;
Lok, Chun‐Nam;
Lai, Yau‐Tsz;
Lee, Pui‐Yan;
Che, Chi‐Ming

Publication type:

Article

Cyclometalated Palladium(II) N-Heterocyclic Carbene Complexes: Anticancer Agents for Potent In Vitro Cytotoxicity and In Vivo Tumor Growth Suppression.

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 39, p. 11935, doi. 10.1002/anie.201602814

By:

Fong, Tommy Tsz-Him;
Lok, Chun-Nam;
Chung, Clive Yik-Sham;
Fung, Yi-Man Eva;
Chow, Pui-Keong;
Wan, Pui-Ki;
Che, Chi-Ming

Publication type:

Article

Anticancer Gold(III) Porphyrins Target Mitochondrial Chaperone Hsp60.

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 4, p. 1387, doi. 10.1002/anie.201509612

By:

Hu, Di;
Liu, Yungen;
Lai, Yau-Tsz;
Tong, Ka-Chung;
Fung, Yi-Man;
Lok, Chun-Nam;
Che, Chi-Ming

Publication type:

Article

Luminescent Cyclometalated Platinum(II) Complex Forms Emissive Intercalating Adducts with Double-Stranded DNA and RNA: Differential Emissions and Anticancer Activities.

Published in:

Angewandte Chemie International Edition, 2014, v. 53, n. 38, p. 10119, doi. 10.1002/anie.201405384

By:

Zou, Taotao;
Liu, Jia;
Lum, Ching Tung;
Ma, Chensheng;
Chan, Ruth Chau-Ting;
Lok, Chun-Nam;
Kwok, Wai-Ming;
Che, Chi-Ming

Publication type:

Article

A Binuclear Gold(I) Complex with Mixed Bridging Diphosphine and Bis(N-Heterocyclic Carbene) Ligands Shows Favorable Thiol Reactivity and Inhibits Tumor Growth and Angiogenesis In Vivo.

Published in:

Angewandte Chemie International Edition, 2014, v. 53, n. 23, p. 5810, doi. 10.1002/anie.201400142

By:

Zou, Taotao;
Lum, Ching Tung;
Lok, Chun‐Nam;
To, Wai‐Pong;
Low, Kam‐Hung;
Che, Chi‐Ming

Publication type:

Article

Efficient Singlet Oxygen Generation by Luminescent 2-(2′-Thienyl)Pyridyl Cyclometalated Platinum(II) Complexes and Their Calixarene Derivatives.

Published in:

Photochemistry & Photobiology, 2010, v. 86, n. 6, p. 1414, doi. 10.1111/j.1751-1097.2010.00809.x

By:

Lai, Siu-Wai;
Liu, Ying;
Zhang, Dong;
Wang, Bin;
Lok, Chun-Nam;
Che, Chi-Ming;
Selke, Matthias

Publication type:

Article

Activity‐based Fluorescent Imaging of Alcohol Dehydrogenase Activity in Living Cells.

Published in:

Analysis & Sensing, 2023, v. 3, n. 6, p. 1, doi. 10.1002/anse.202300012

By:

Yau, Wai Yin;
Lai, Samuel Kin‐Man;
Blasco, Pilar;
Li, Xuechen;
Ng, Kwan Ming;
Lok, Chun Nam;
Au‐Yeung, Ho Yu

Publication type:

Article

Topical Delivery of Silver Nanoparticles Promotes Wound Healing.

Published in:

ChemMedChem, 2007, v. 2, n. 1, p. 129, doi. 10.1002/cmdc.200600171

By:

Tian, Jun;
Wong, Kenneth K. Y.;
Ho, Chi-Ming;
Lok, Chun-Nam;
Yu, Wing-Yiu;
Che, Chi-Ming;
Chiu, Jen-Fu;
Tam, Paul K. H.

Publication type:

Article

An Antitumor Bis(N‐Heterocyclic Carbene)Platinum(II) Complex That Engages Asparagine Synthetase as an Anticancer Target.

Published in:

Angewandte Chemie, 2019, v. 131, n. 32, p. 11030, doi. 10.1002/ange.201904131

By:

Hu, Di;
Yang, Chen;
Lok, Chun‐Nam;
Xing, Fangrong;
Lee, Pui‐Yan;
Fung, Yi Man Eva;
Jiang, Haibo;
Che, Chi‐Ming

Publication type:

Article

Cyclometalated Gold(III) Complexes Containing N-Heterocyclic Carbene Ligands Engage Multiple Anti-Cancer Molecular Targets.

Published in:

Angewandte Chemie, 2017, v. 129, n. 14, p. 3950, doi. 10.1002/ange.201612583

By:

Fung, Sin Ki;
Zou, Taotao;
Cao, Bei;
Lee, Pui ‐ Yan;
Fung, Yi Man Eva;
Hu, Di;
Lok, Chun ‐ Nam;
Che, Chi ‐ Ming

Publication type:

Article

A Macrocyclic Ruthenium(III) Complex Inhibits Angiogenesis with Down-Regulation of Vascular Endothelial Growth Factor Receptor-2 and Suppresses Tumor Growth In Vivo.

Published in:

Angewandte Chemie, 2016, v. 128, n. 43, p. 13722, doi. 10.1002/ange.201608094

By:

Kwong, Wai‐Lun;
Lam, Kar‐Yee;
Lok, Chun‐Nam;
Lai, Yau‐Tsz;
Lee, Pui‐Yan;
Che, Chi‐Ming

Publication type:

Article

Cyclometalated Palladium(II) N-Heterocyclic Carbene Complexes: Anticancer Agents for Potent In Vitro Cytotoxicity and In Vivo Tumor Growth Suppression.

Published in:

Angewandte Chemie, 2016, v. 128, n. 39, p. 12114, doi. 10.1002/ange.201602814

By:

Fong, Tommy Tsz ‐ Him;
Lok, Chun ‐ Nam;
Chung, Clive Yik ‐ Sham;
Fung, Yi ‐ Man Eva;
Chow, Pui ‐ Keong;
Wan, Pui ‐ Ki;
Che, Chi ‐ Ming

Publication type:

Article

Anticancer Gold(III) Porphyrins Target Mitochondrial Chaperone Hsp60.

Published in:

Angewandte Chemie, 2016, v. 128, n. 4, p. 1409, doi. 10.1002/ange.201509612

By:

Hu, Di;
Liu, Yungen;
Lai, Yau‐Tsz;
Tong, Ka‐Chung;
Fung, Yi‐Man;
Lok, Chun‐Nam;
Che, Chi‐Ming

Publication type:

Article

Luminescent Cyclometalated Platinum(II) Complex Forms Emissive Intercalating Adducts with Double-Stranded DNA and RNA: Differential Emissions and Anticancer Activities.

Published in:

Angewandte Chemie, 2014, v. 126, n. 38, p. 10283, doi. 10.1002/ange.201405384

By:

Zou, Taotao;
Liu, Jia;
Lum, Ching Tung;
Ma, Chensheng;
Chan, Ruth Chau-Ting;
Lok, Chun-Nam;
Kwok, Wai-Ming;
Che, Chi-Ming

Publication type:

Article

A Binuclear Gold(I) Complex with Mixed Bridging Diphosphine and Bis(N-Heterocyclic Carbene) Ligands Shows Favorable Thiol Reactivity and Inhibits Tumor Growth and Angiogenesis In Vivo.

Published in:

Angewandte Chemie, 2014, v. 126, n. 23, p. 5920, doi. 10.1002/ange.201400142

By:

Zou, Taotao;
Lum, Ching Tung;
Lok, Chun ‐ Nam;
To, Wai ‐ Pong;
Low, Kam ‐ Hung;
Che, Chi ‐ Ming

Publication type:

Article

Delayed application of silver nanoparticles reveals the role of early inflammation in burn wound healing.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-63464-z

By:

Zhang, Kangjun;
Lui, Vincent C. H.;
Chen, Yan;
Lok, Chun Nam;
Wong, Kenneth K. Y.

Publication type:

Article

Anticancer auranofin engages 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) as a target.

Published in:

Metallomics, 2019, v. 11, n. 11, p. 1925, doi. 10.1039/c9mt00185a

By:

Tian, Songhai;
Siu, Fung-Ming;
Lok, Chun-Nam;
Fung, Yi Man Eva;
Che, Chi-Ming

Publication type:

Article

Multifunctional Microparticles Incorporating Gold Compound Inhibit Human Lung Cancer Xenograft.

Published in:

Pharmaceutical Research, 2020, v. 37, n. 11, p. 1, doi. 10.1007/s11095-020-02931-8

By:

Lee, Pui -Yan;
Lok, Chun-Nam;
Che, Chi-Ming;
Kao, Weiyuan John

Publication type:

Article

A Multifunctional Hydrogel Delivers Gold Compound and Inhibits Human Lung Cancer Xenograft.

Published in:

Pharmaceutical Research, 2019, v. 36, n. 4, p. N.PAG, doi. 10.1007/s11095-019-2581-z

By:

Lee, Puiyan;
Lok, Chun-Nam;
Che, Chi-Ming;
Kao, Weiyuan John

Publication type:

Article

Proteomic and transcriptomic study on the action of a cytotoxic saponin (Polyphyllin D): Induction of endoplasmic reticulum stress and mitochondria-mediated apoptotic pathways.

Published in:

Proteomics, 2008, v. 8, n. 15, p. 3105, doi. 10.1002/pmic.200700829

By:

Siu, Fung-Ming;
Ma, Dik-Lung;
Cheung, Yee-Wai;
Lok, Chun-Nam;
Yan, Kun;
Yang, Zhiqi;
Yang, Mengsu;
Xu, SongXiao;
Ko, Ben Chi-Bun;
He, Qing-Yu;
Che, Chi-Ming

Publication type:

Article

Stable Anticancer Gold(III)-Porphyrin Complexes: Effects of Porphyrin Structure.

Published in:

Chemistry - A European Journal, 2010, v. 16, n. 10, p. 3097, doi. 10.1002/chem.200902741

By:

Sun, Raymond Wai-Yin;
Li, Carrie Ka-Lei;
Ma, Dik-Lung;
Yan, Jessie Jing;
Lok, Chun-Nam;
Leung, Chung-Hang;
Zhu, Nianyong;
Che, Chi-Ming

Publication type:

Article

Cover Picture: Stable Anticancer Gold(III)-Porphyrin Complexes: Effects of Porphyrin Structure (Chem. Eur. J. 10/2010).

Published in:

Chemistry - A European Journal, 2010, v. 16, n. 10, p. 2951, doi. 10.1002/chem.201090039

By:

Sun, Raymond Wai-Yin;
Li, Carrie Ka-Lei;
Ma, Dik-Lung;
Yan, Jessie Jing;
Lok, Chun-Nam;
Leung, Chung-Hang;
Zhu, Nianyong;
Che, Chi-Ming

Publication type:

Article

Luminescent platinum(II) complexes with functionalized N-heterocyclic carbene or diphosphine selectively probe mismatched and abasic DNA.

Published in:

Nature Communications, 2016, v. 7, n. 2, p. 10655, doi. 10.1038/ncomms10655

By:

Fung, Sin Ki;
Zou, Taotao;
Cao, Bei;
Chen, Tianfeng;
To, Wai-Pong;
Yang, Chen;
Lok, Chun-Nam;
Che, Chi-Ming

Publication type:

Article

Anti-Cancer Iron(II) Complexes of Pentadentate N-Donor Ligands: Cytotoxicity, Transcriptomics Analyses, and Mechanisms of Action.

Published in:

Chemistry - A European Journal, 2015, v. 21, n. 7, p. 3062, doi. 10.1002/chem.201404749

By:

Kwong, Wai ‐ Lun;
Lok, Chun ‐ Nam;
Tse, Chun ‐ Wai;
Wong, Ella Lai ‐ Ming;
Che, Chi ‐ Ming

Publication type:

Article

Controlled-Release Systems for Metal-Based Nanomedicine: Encapsulated/Self-Assembled Nanoparticles of Anticancer Gold(III)/Platinum(II) Complexes and Antimicrobial Silver Nanoparticles.

Published in:

Advanced Materials, 2014, v. 26, n. 31, p. 5550, doi. 10.1002/adma.201305617

By:

Lok, Chun-Nam;
Zou, Taotao;
Zhang, Jing-Jing;
Lin, Iris Wing-Shan;
Che, Chi-Ming

Publication type:

Article

Oligodeoxynucleotide decoy therapy blocks type 1 procollagen transcription and the prolyl hydroxylase β subunit translation.

Published in:

Journal of Cellular Biochemistry, 2008, v. 103, n. 4, p. 1066, doi. 10.1002/jcb.21477

By:

Lok, Chun-Nam;
Ehrlich, H. Paul;
White, Sheryl L.;
Buttolph, Thomas R.;
Cutroneo, Kenneth R.;
Chiu, Jen-Fu

Publication type:

Article

Oxidative Dissolution of Silver Nanoparticles by Dioxygen: A Kinetic and Mechanistic Study.

Published in:

Chemistry - An Asian Journal, 2011, v. 6, n. 9, p. 2506, doi. 10.1002/asia.201100034

By:

Ho, Chi-Ming;
Wong, Chi-Kit;
Yau, Sammi King-Woon;
Lok, Chun-Nam;
Che, Chi-Ming

Publication type:

Article

Ruthenium(III) Complexes of Macrocyclic Tertiary Amines Mediated NO Release from S-Nitrosothiols under in vitro and in vivo Conditions.

Published in:

Chemistry - An Asian Journal, 2010, v. 5, n. 9, p. 1965, doi. 10.1002/asia.201000368

By:

Ho, Chi-Ming;
Leung, Hiu-Chi;
Lok, Chun-Nam;
Che, Chi-Ming

Publication type:

Article

Oxidative Dissolution of Silver Nanoparticles by Biologically Relevant Oxidants: A Kinetic and Mechanistic Study.

Published in:

Chemistry - An Asian Journal, 2010, v. 5, n. 2, p. 285, doi. 10.1002/asia.200900387

By:

Ho, Chi-Ming;
Yau, Sammi King-Woon;
Lok, Chun-Nam;
So, Man-Ho;
Che, Chi-Ming

Publication type:

Article