Works matching AU Loiselle, Alayna E.

Results: 37

Epitenon-derived progenitors drive fibrosis and regeneration after flexor tendon injury in a spatially-dependent manner.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60704-6

By:

Nichols, Anne E. C.;
Benoodt, Lauren;
Adjei-Sowah, Emmanuella;
Jerreld, Kyle;
Kollar, Alexander;
Ketonis, Constantinos;
Loiselle, Alayna E.

Publication type:

Article

Depletion of Scleraxis-lineage cells during tendon healing transiently impairs multi-scale restoration of tendon structure during early healing.

Published in:

PLoS ONE, 2022, v. 17, n. 10, p. 1, doi. 10.1371/journal.pone.0274227

By:

Korcari, Antonion;
Muscat, Samantha;
McGinn, Elizabeth;
Buckley, Mark R.;
Loiselle, Alayna E.

Publication type:

Article

Pharmacological antagonism of Ccr2+ cell recruitment to facilitate regenerative tendon healing.

Published in:

Journal of Orthopaedic Research, 2025, v. 43, n. 2, p. 243, doi. 10.1002/jor.25986

By:

Smolyak, Gilbert;
Rodenhouse, Andrew;
Nichols, Anne E. C.;
Ketonis, Constantinos;
Loiselle, Alayna E.

Publication type:

Article

Effects of tamoxifen on tendon homeostasis and healing: Considerations for the use of tamoxifen‐inducible mouse models.

Published in:

Journal of Orthopaedic Research, 2021, v. 39, n. 7, p. 1572, doi. 10.1002/jor.24767

By:

Best, Katherine T.;
Studentsova, Valentina;
Ackerman, Jessica E.;
Nichols, Anne E. C.;
Myers, Marlin;
Cobb, Justin;
Knapp, Emma;
Awad, Hani A.;
Loiselle, Alayna E.

Publication type:

Article

Effects of Type II Diabetes Mellitus on Tendon Homeostasis and Healing.

Published in:

Journal of Orthopaedic Research, 2020, v. 38, n. 1, p. 13, doi. 10.1002/jor.24388

By:

Nichols, Anne E. C.;
Oh, Irvin;
Loiselle, Alayna E.

Publication type:

Article

Non‐Invasive Ultrasound Quantification of Scar Tissue Volume Identifies Early Functional Changes During Tendon Healing.

Published in:

Journal of Orthopaedic Research, 2019, v. 37, n. 11, p. 2476, doi. 10.1002/jor.24397

By:

Ackerman, Jessica E.;
Studentsova, Valentina;
Myers, Marlin;
Buckley, Mark R.;
Richards, Michael S.;
Loiselle, Alayna E.

Publication type:

Article

Aging does not alter tendon mechanical properties during homeostasis, but does impair flexor tendon healing.

Published in:

Journal of Orthopaedic Research, 2017, v. 35, n. 12, p. 2716, doi. 10.1002/jor.23580

By:

Ackerman, Jessica E.;
Bah, Ibrahima;
Jonason, Jennifer H.;
Buckley, Mark R.;
Loiselle, Alayna E.

Publication type:

Article

Development of antisense oligonucleotide (ASO) technology against Tgf-β signaling to prevent scarring during flexor tendon repair.

Published in:

Journal of Orthopaedic Research, 2015, v. 33, n. 6, p. 859, doi. 10.1002/jor.22890

By:

Loiselle, Alayna E.;
Yukata, Kiminori;
Geary, Michael B.;
Kondabolu, Sirish;
Shi, Shanshan;
Jonason, Jennifer H.;
Awad, Hani A.;
O'Keefe, Regis J.

Publication type:

Article

Parathyroid hormone 1-34 enhances extracellular matrix deposition and organization during flexor tendon repair.

Published in:

Journal of Orthopaedic Research, 2015, v. 33, n. 1, p. 17, doi. 10.1002/jor.22735

By:

Lee, Daniel J.;
Southgate, Richard D.;
Farhat, Youssef M.;
Loiselle, Alayna E.;
Hammert, Warren C.;
Awad, Hani A.;
O'Keefe, Regis J.

Publication type:

Article

Osteoblast and osteocyte-specific loss of Connexin43 results in delayed bone formation and healing during murine fracture healing.

Published in:

Journal of Orthopaedic Research, 2013, v. 31, n. 1, p. 147, doi. 10.1002/jor.22178

By:

Loiselle, Alayna E.;
Paul, Emmanuel M.;
Lewis, Gregory S.;
Donahue, Henry J.

Publication type:

Article

Optimizing the osteogenic potential of adult stem cells for skeletal regeneration.

Published in:

Journal of Orthopaedic Research, 2011, v. 29, n. 11, p. 1627, doi. 10.1002/jor.21441

By:

Lim, Jung Yul;
Loiselle, Alayna E.;
Lee, Jeong Soon;
Zhang, Yue;
Salvi, Joshua D.;
Donahue, Henry J.

Publication type:

Article

Impact of Smad3 loss of function on scarring and adhesion formation during tendon healing.

Published in:

Journal of Orthopaedic Research, 2011, v. 29, n. 5, p. 684, doi. 10.1002/jor.21235

By:

Katzel, Evan B.;
Wolenski, Matthew;
Loiselle, Alayna E.;
Basile, Patrick;
Flick, Lisa M.;
Langstein, Howard N.;
Hilton, Matthew J.;
Awad, Hani A.;
Hammert, Warren C.;
O'Keefe, Regis J.

Publication type:

Article

Increased Ca<sup>2+</sup> signaling through Ca<sub>V</sub>1.2 induces tendon hypertrophy with increased collagen fibrillogenesis and biomechanical properties.

Published in:

FASEB Journal, 2023, v. 37, n. 7, p. 1, doi. 10.1096/fj.202300607R

By:

Li, Haiyin;
Korcari, Antonion;
Ciufo, David;
Mendias, Christopher L.;
Rodeo, Scott A.;
Buckley, Mark R.;
Loiselle, Alayna E.;
Pitt, Geoffrey S.;
Cao, Chike

Publication type:

Article

CCR2 is expressed by tendon resident macrophage and T cells, while CCR2 deficiency impairs tendon healing via blunted involvement of tendon‐resident and circulating monocytes/macrophages.

Published in:

FASEB Journal, 2022, v. 36, n. 11, p. 1, doi. 10.1096/fj.202201162R

By:

Muscat, Samantha;
Nichols, Anne E. C.;
Gira, Emma;
Loiselle, Alayna E.

Publication type:

Article

Impact of isolation method on cellular activation and presence of specific tendon cell subpopulations during in vitro culture.

Published in:

FASEB Journal, 2021, v. 35, n. 7, p. 1, doi. 10.1096/fj.202100405R

By:

Nichols, Anne E. C.;
Muscat, Samantha N.;
Miller, Sarah E.;
Green, Luke J.;
Richards, Michael S.;
Loiselle, Alayna E.

Publication type:

Article

Current cutting-edge omics techniques on musculoskeletal tissues and diseases.

Published in:

Bone Research, 2025, v. 13, n. 1, p. 1, doi. 10.1038/s41413-025-00442-z

By:

Li, Xiaofei;
Fang, Liang;
Zhou, Renpeng;
Yao, Lutian;
Clayton, Sade W.;
Muscat, Samantha;
Kamm, Dakota R.;
Wang, Cuicui;
Liu, Chuan-Ju;
Qin, Ling;
Tower, Robert J.;
Karner, Courtney M.;
Guilak, Farshid;
Tang, Simon Y.;
Loiselle, Alayna E.;
Meyer, Gretchen A.;
Shen, Jie

Publication type:

Article

Impact of aging on tendon homeostasis, tendinopathy development, and impaired healing.

Published in:

Connective Tissue Research, 2023, v. 64, n. 1, p. 1, doi. 10.1080/03008207.2022.2102004

By:

Korcari, Antonion;
Przybelski, Samantha J.;
Gingery, Anne;
Loiselle, Alayna E.

Publication type:

Article

Scleraxis-lineage cell depletion improves tendon healing and disrupts adult tendon homeostasis.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.62203

By:

Best, Katherine T.;
Korcari, Antonion;
Mora, Keshia E.;
Nichols, Anne E. C.;
Muscat, Samantha N.;
Knapp, Emma;
Buckley, Mark R.;
Loiselle, Alayna E.

Publication type:

Article

Obesity/Type II diabetes alters macrophage polarization resulting in a fibrotic tendon healing response.

Published in:

PLoS ONE, 2017, v. 12, n. 7, p. 1, doi. 10.1371/journal.pone.0181127

By:

Ackerman, Jessica E.;
Geary, Michael B.;
Orner, Caitlin A.;
Bawany, Fatima;
Loiselle, Alayna E.

Publication type:

Article

Metabolic Regulation of Tendon Inflammation and Healing Following Injury.

Published in:

Current Rheumatology Reports, 2021, v. 23, n. 3, p. 1, doi. 10.1007/s11926-021-00981-4

By:

Ackerman, Jessica E.;
Best, Katherine T.;
Muscat, Samantha N.;
Loiselle, Alayna E.

Publication type:

Article

Deletion of NFKB1 enhances canonical NF-κB signaling and increases macrophage and myofibroblast content during tendon healing.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-47461-5

By:

Best, Katherine T.;
Lee, Fredella K.;
Knapp, Emma;
Awad, Hani A.;
Loiselle, Alayna E.

Publication type:

Article

Remodeling of murine intrasynovial tendon adhesions following injury: MMP and neotendon gene expression.

Published in:

Journal of Orthopaedic Research, 2009, v. 27, n. 6, p. 833, doi. 10.1002/jor.20769

By:

Loiselle, Alayna E.;
Bragdon, Gwynne A.;
Jacobson, Justin A.;
Hasslund, Sys;
Cortes, Zenia E.;
Schwarz, Edward M.;
Mitten, David J.;
Awad, Hani A.;
O'Keefe, Regis J.

Publication type:

Article

Single-cell transcriptomics of popliteal lymphatic vessels and peripheral veins reveals altered lymphatic muscle and immune cell populations in the TNF-Tg arthritis model.

Published in:

Arthritis Research & Therapy, 2022, v. 24, n. 1, p. 1, doi. 10.1186/s13075-022-02730-z

By:

Kenney, H. Mark;
Wu, Chia-Lung;
Loiselle, Alayna E.;
Xing, Lianping;
Ritchlin, Christopher T.;
Schwarz, Edward M.

Publication type:

Article

Shifting Paradigms on the Role of Connexin43 in the Skeletal Response to Mechanical Load.

Published in:

Journal of Bone & Mineral Research, 2014, v. 29, n. 2, p. 275, doi. 10.1002/jbmr.2165

By:

Lloyd, Shane A;
Loiselle, Alayna E;
Zhang, Yue;
Donahue, Henry J

Publication type:

Article

TAK1 Regulates Cartilage and Joint Development via the MAPK and BMP Signaling Pathways.

Published in:

Journal of Bone & Mineral Research, 2010, v. 25, n. 8, p. 1784, doi. 10.1002/jbmr.79

By:

Gunnell, Lea M.;
Jonason, Jennifer H.;
Loiselle, Alayna E.;
Kohn, Anat;
Schwarz, Edward M.;
Hilton, Matthew J.;
O'Keefe, Regis J.

Publication type:

Article

Scleraxis lineage cells contribute to organized bridging tissue during tendon healing and identify a subpopulation of resident tendon cells.

Published in:

FASEB Journal, 2019, v. 33, n. 7, p. 8578, doi. 10.1096/fj.201900130RR

By:

Best, Katherine T.;
Loiselle, Alayna E.

Publication type:

Article

Evidence for the role of connexin 43-mediated intercellular communication in the process of intracortical bone resorption via osteocytic osteolysis.

Published in:

BMC Musculoskeletal Disorders, 2014, v. 15, n. 1, p. 1, doi. 10.1186/1471-2474-15-122

By:

Lloyd, Shane A.;
Loiselle, Alayna E.;
Yue Zhang;
Donahue, Henry J.

Publication type:

Article

Evidence for the role of connexin 43-mediated intercellular communication in the process of intracortical bone resorption via osteocytic osteolysis.

Published in:

2014

By:

Lloyd, Shane A;
Loiselle, Alayna E;
Zhang, Yue;
Donahue, Henry J

Publication type:

journal article

Inhibition of the Prostaglandin EP-1 Receptor in Periosteum Progenitor Cells Enhances Osteoblast Differentiation and Fracture Repair.

Published in:

Annals of Biomedical Engineering, 2020, v. 48, n. 3, p. 927, doi. 10.1007/s10439-019-02264-7

By:

Feigenson, Marina;
Jonason, Jennifer H.;
Shen, Jie;
Loiselle, Alayna E.;
Awad, Hani A.;
O'Keefe, Regis J.

Publication type:

Article

Ogerin induced activation of Gpr68 alters tendon healing.

Published in:

FASEB Bioadvances, 2025, v. 7, n. 5, p. 1, doi. 10.1096/fba.2024-00236

By:

Rodenhouse, Andrew;
Smolyak, Gilbert;
Adjei‐Sowah, Emmanuela;
Adhikari, Neeta;
Muscat, Samantha;
Okutani, Takuma;
Ketonis, Constantinos;
Nichols, Anne E. C.;
Kottmann, Robert M.;
Loiselle, Alayna E.

Publication type:

Article

Scleraxis-lineage cells are required for tendon homeostasis and their depletion induces an accelerated extracellular matrix aging phenotype.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.84194

By:

Korcari, Antonion;
Nichols, Anne E. C.;
Buckley, Mark R.;
Loiselle, Alayna E.

Publication type:

Article

NF-κB activation persists into the remodeling phase of tendon healing and promotes myofibroblast survival.

Published in:

Science Signaling, 2020, v. 13, n. 658, p. 1, doi. 10.1126/scisignal.abb7209

By:

Best, Katherine T.;
Nichols, Anne E. C.;
Knapp, Emma;
Hammert, Warren C.;
Ketonis, Constantinos;
Jonason, Jennifer H.;
Awad, Hani A.;
Loiselle, Alayna E.

Publication type:

Article

Systemic EP4 Inhibition Increases Adhesion Formation in a Murine Model of Flexor Tendon Repair.

Published in:

PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0136351

By:

Geary, Michael B.;
Orner, Caitlin A.;
Bawany, Fatima;
Awad, Hani A.;
Hammert, Warren C.;
O’Keefe, Regis J.;
Loiselle, Alayna E.

Publication type:

Article

Inhibition of GSK-3β Rescues the Impairments in Bone Formation and Mechanical Properties Associated with Fracture Healing in Osteoblast Selective Connexin 43 Deficient Mice.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0081399

By:

Loiselle, Alayna E.;
Lloyd, Shane A. J.;
Paul, Emmanuel M.;
Lewis, Gregory S.;
Donahue, Henry J.

Publication type:

Article

Bone Marrow-Derived Matrix Metalloproteinase-9 Is Associated with Fibrous Adhesion Formation after Murine Flexor Tendon Injury.

Published in:

PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0040602

By:

Loiselle, Alayna E.;
Frisch, Benjamin J.;
Wolenski, Matthew;
Jacobson, Justin A.;
Calvi, Laura M.;
Schwarz, Edward M.;
Awad, Hani A.;
O'Keefe, Regis J.

Publication type:

Article

The surgical destabilization of the abductor muscle leads to development of instability-associated hip osteoarthritis in mice.

Published in:

Journal of Hip Preservation Surgery, 2023, v. 10, n. 3/4, p. 158, doi. 10.1093/jhps/hnad015

By:

Geary, Michael B;
Orner, Caitlin A;
Shammas, Helen;
Reuter, John M;
Loiselle, Alayna E;
Giordano, Brian D;
Wu, Chia-Lung

Publication type:

Article

The Micromechanical Environment of the Impinged Achilles Tendon.

Published in:

Small, 2024, v. 20, n. 44, p. 1, doi. 10.1002/smll.202401015

By:

Mora, Keshia E.;
Mlawer, Samuel J.;
Loiselle, Alayna E.;
Buckley, Mark R.

Publication type:

Article