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Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-09825-2
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- Article
Corrigendum: Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2<sup>*</sup>R47H.
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- 2022
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- Publication type:
- Correction Notice
Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2*R47H.
- Published in:
- Frontiers in Aging Neuroscience, 2021, v. 13, p. 1, doi. 10.3389/fnagi.2021.735524
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- Article
Comprehensive Evaluation of the 5XFAD Mouse Model for Preclinical Testing Applications: A MODEL-AD Study.
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- Frontiers in Aging Neuroscience, 2021, v. 13, p. 1, doi. 10.3389/fnagi.2021.713726
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- Article
Transcriptomic profiling of myeloid cells in Alzheimer's Disease brain illustrates heterogeneity of microglia endolysosomal subtypes.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.062391
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- Article
Integrating multimodal data to support Alzheimer's disease target prioritization.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.052334
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- Article
Microglia across the spectrum from homeostatic to disease phenotypes display enhanced inflammatory responses in human postmortem AD brain.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.057792
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- Article
Microglia subtype transcriptomes differ between Alzheimer Disease and control human postmortem brain samples.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.058474
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- Article
N‐of‐1‐pathways transcriptomic analysis reveals distinct subtypes of Alzheimer's disease: Development of new models and analysis methods/novel assays and technologies.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.046575
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- Article
Leveraging predicted gene expression data for recapitulation of gene coexpression network analysis associations with AD pathology and cognitive decline: Genetics/omics and systems biology.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.046394
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- Article
Agora: An open platform for exploration of Alzheimer's disease evidence: Genetics/omics and systems biology.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.046129
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- Publication type:
- Article
Single nuclei RNA‐seq data analysis identifies glial cell lineages associated with Alzheimer's disease severity: Genetics: Genetics and omics of AD I.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.046122
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- Article
Brain transcriptome wide association study (TWAS) implicates 8 genes across 6 loci in Alzheimer's disease: Genetics: Genetics and omics of AD I.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.044839
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- Article
Integrating human brain proteomes and genome‐wide association results implicates new genes in Alzheimer's disease: Functionalizing genetic variants in Alzheimer's disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043865
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- Article
P4‐479: METHODS TO ASSESS CELL‐TYPE‐SPECIFIC, BIOLOGICAL NETWORKS OF ALZHEIMER'S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1496, doi. 10.1016/j.jalz.2019.08.025
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- Article
P4‐098: TRANSCRIPTOMIC ALTERATIONS DRIVEN BY THE TREM2*R47H ALLELE VARY ACROSS DIFFERENT TRANSGENIC MOUSE MODELS.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1312, doi. 10.1016/j.jalz.2019.06.3758
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- Article
P4‐120: COMMUNITY‐POWERED, RADICALLY OPEN TECHNOLOGIES TO ACCELERATE ALZHEIMER'S DISEASE THERAPEUTIC DISCOVERY.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1322, doi. 10.1016/j.jalz.2019.06.3781
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- Article
P4‐119: MOLECULAR ESTIMATION OF ALZHEIMER'S DISEASE PROGRESSION.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1321, doi. 10.1016/j.jalz.2019.06.3780
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- Article
P4‐113: AGORA: A PLATFORM FOR THE DEMOCRATIZATION OF ALZHEIMER'S DISEASE TARGET EVIDENCE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1319, doi. 10.1016/j.jalz.2019.06.3774
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- Article
O4‐10‐04: LARGE‐SCALE PROTEOMIC ANALYSIS OF HUMAN PREFRONTAL CORTEX IDENTIFIES PROTEINS ASSOCIATED WITH COGNITIVE TRAJECTORY IN ADVANCED AGE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1260, doi. 10.1016/j.jalz.2019.06.4797
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- Article
O4‐10‐03: FUNCTIONAL DISSECTION OF ALZHEIMER'S DISEASE BRAIN GENE EXPRESSION SIGNATURES IN HUMANS AND MOUSE MODELS.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1260, doi. 10.1016/j.jalz.2019.06.4796
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- Article
P3‐151: BRAIN MICRORNAS ASSOCIATED WITH LATE‐LIFE DEPRESSION ARE ALSO LINKED TO COGNITIVE TRAJECTORY AND DEMENTIA.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P990, doi. 10.1016/j.jalz.2019.06.3180
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- Article
P3‐142: STRATIFICATION OF ALZHEIMER'S PATIENTS USING POSTMORTEM BRAIN CO‐EXPRESSION DATA REVEALS NOVEL GENETIC MODIFIERS MEDIATING INFLAMMATORY AGING.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P986, doi. 10.1016/j.jalz.2019.06.3170
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- Article
P2‐133: INITIAL CHARACTERIZATION OF NOVEL MOUSE MODELS OF LATE ONSET ALZHEIMER'S DISEASE BASED ON HUMAN GENETIC ASSOCIATIONS.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P623, doi. 10.1016/j.jalz.2019.06.2540
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- Article
P2‐105: A NOVEL SYSTEMS BIOLOGY APPROACH TO EVALUATE MOUSE MODELS OF LATE ONSET ALZHEIMER'S DISEASE: NCOUNTER MOUSE AD PANEL.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P612, doi. 10.1016/j.jalz.2019.06.2512
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- Article
P4‐230: A GENOMIC AND CELL FUNCTION APPROACH TO IDENTIFYING CELL‐TYPE‐SPECIFIC BIOLOGICAL NETWORKS IN ALZHEIMER'S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1530, doi. 10.1016/j.jalz.2018.07.051
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- Article
O3‐03‐02: SYSTEMS BIOLOGY RANKING OF CANDIDATE ALZHEIMER'S DRIVER GENES IDENTIFIES NEW GENETIC DRIVERS OF ALZHEIMER'S DISEASE ETIOLOGY.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1015, doi. 10.1016/j.jalz.2018.06.2783
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- Article
Quantitative Trait Loci for the Circadian Clock in Neurospora crassa.
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- Genetics, 2007, v. 177, n. 4, p. 2335, doi. 10.1534/genetics.107.077958
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- Article
Sparse expression bases in cancer reveal tumor drivers.
- Published in:
- Nucleic Acids Research, 2015, v. 43, n. 3, p. 1332, doi. 10.1093/nar/gku1290
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- Article
Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27204-9
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- Publication type:
- Article
Multi-tissue neocortical transcriptome-wide association study implicates 8 genes across 6 genomic loci in Alzheimer's disease.
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- Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00890-2
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- Article
UNDERSTANDING THE MOLECULAR ETIOLOGY OF ALZHEIMER'S DISEASE ACROSS SEVEN DIFFERENT BRAIN REGIONS.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1491, doi. 10.1016/j.jalz.2017.07.577
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- Article
CROSS STUDY INTEGRATIVE NETWORK ANALYSIS IDENTIFICATION OF AD DISEASE ETIOLOGY.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P645, doi. 10.1016/j.jalz.2017.06.750
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- Publication type:
- Article
INTEGRATIVE NETWORK ANALYSIS OF MULTIPLE ALZHEIMER'S DISEASE RNASEQ STUDIES FROM THE ACCELERATING MEDICINE PARTNERSHIP-ALZHEIMER'S DISEASE CONSORTIUM.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P1026, doi. 10.1016/j.jalz.2016.06.2120
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- Publication type:
- Article
SPINE: SParse eIgengene NEtwork Linking Gene Expression Clusters in Dehalococcoides mccartyi to Perturbations in Experimental Conditions.
- Published in:
- PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0118404
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- Publication type:
- Article
Transcriptomic stratification of late-onset Alzheimer's cases reveals novel genetic modifiers of disease pathology.
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- PLoS Genetics, 2020, v. 16, n. 6, p. 1, doi. 10.1371/journal.pgen.1008775
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- Publication type:
- Article
Brain microRNAs associated with late-life depressive symptoms are also associated with cognitive trajectory and dementia.
- Published in:
- NPJ Genomic Medicine, 2020, v. 5, n. 1, p. 1, doi. 10.1038/s41525-019-0113-8
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- Publication type:
- Article
Large-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09613-z
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- Publication type:
- Article
A variational Bayes algorithm for fast and accurate multiple locus genome-wide association analysis.
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- BMC Bioinformatics, 2010, v. 11, p. 1, doi. 10.1186/1471-2105-11-58
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- Publication type:
- Article
Rare Variation Facilitates Inferences of Fine-Scale Population Structure in Humans.
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- Molecular Biology & Evolution, 2015, v. 32, n. 3, p. 653, doi. 10.1093/molbev/msu326
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- Article
Simultaneously Testing for Marginal Genetic Association and Gene-Environment Interaction.
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- American Journal of Epidemiology, 2012, v. 176, n. 2, p. 164, doi. 10.1093/aje/kwr521
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- Publication type:
- Article
PUMA: A Unified Framework for Penalized Multiple Regression Analysis of GWAS Data.
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- PLoS Computational Biology, 2013, v. 9, n. 6, p. 1, doi. 10.1371/journal.pcbi.1003101
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- Publication type:
- Article
Improving Breast Cancer Survival Analysis through Competition-Based Multidimensional Modeling
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- PLoS Computational Biology, 2013, v. 9, n. 5, p. 1, doi. 10.1371/journal.pcbi.1003047
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- Article
Gene Expression Network Reconstruction by Convex Feature Selection when Incorporating Genetic Perturbations.
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- PLoS Computational Biology, 2010, v. 6, n. 12, p. 1, doi. 10.1371/journal.pcbi.1001014
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- Article
Identifying Network Perturbation in Cancer.
- Published in:
- PLoS Computational Biology, 2016, v. 12, n. 5, p. 1, doi. 10.1371/journal.pcbi.1004888
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- Article
Genetic and multi‐omic risk assessment of Alzheimer's disease implicates core associated biological domains.
- Published in:
- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2024, v. 10, n. 2, p. 1, doi. 10.1002/trc2.12461
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- Publication type:
- Article
Model organism development and evaluation for late‐onset Alzheimer's disease: MODEL‐AD.
- Published in:
- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2020, v. 6, n. 1, p. 1, doi. 10.1002/trc2.12110
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- Publication type:
- Article
Transfer learning‐trained convolutional neural networks identify novel MRI biomarkers of Alzheimer's disease progression.
- Published in:
- Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2021, v. 13, n. 1, p. 1, doi. 10.1002/dad2.12140
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- Article
A machine learning approach to integrate big data for precision medicine in acute myeloid leukemia.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02465-5
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- Publication type:
- Article
A Meta-Analysis and Genome-Wide Association Study of Platelet Count and Mean Platelet Volume in African Americans.
- Published in:
- PLoS Genetics, 2012, v. 8, n. 3, p. 1, doi. 10.1371/journal.pgen.1002491
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- Publication type:
- Article