Works matching AU Loewe, Axel

Results: 74

Global Sensitivity Analysis and Uncertainty Quantification for Simulated Atrial Electrocardiograms.

Published in:

Metrology, 2023, v. 3, n. 1, p. 1, doi. 10.3390/metrology3010001

By:

Winkler, Benjamin;
Nagel, Claudia;
Farchmin, Nando;
Heidenreich, Sebastian;
Loewe, Axel;
Dössel, Olaf;
Bär, Markus

Publication type:

Article

Non-Invasive and Quantitative Estimation of Left Atrial Fibrosis Based on P Waves of the 12-Lead ECG—A Large-Scale Computational Study Covering Anatomical Variability.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 8, p. 1797, doi. 10.3390/jcm10081797

By:

Nagel, Claudia;
Luongo, Giorgio;
Azzolin, Luca;
Schuler, Steffen;
Dössel, Olaf;
Loewe, Axel

Publication type:

Article

Electro-Mechanical Whole-Heart Digital Twins: A Fully Coupled Multi-Physics Approach.

Published in:

Mathematics (2227-7390), 2021, v. 9, n. 11, p. 1247, doi. 10.3390/math9111247

By:

Gerach, Tobias;
Schuler, Steffen;
Fröhlich, Jonathan;
Lindner, Laura;
Kovacheva, Ekaterina;
Moss, Robin;
Wülfers, Eike Moritz;
Seemann, Gunnar;
Wieners, Christian;
Loewe, Axel

Publication type:

Article

A Review of Healthy and Fibrotic Myocardium Microstructure Modeling and Corresponding Intracardiac Electrograms.

Published in:

Frontiers in Physiology, 2024, p. 1, doi. 10.3389/fphys.2022.908069

By:

Sánchez, Jorge;
Loewe, Axel

Publication type:

Article

Efficient time splitting schemes for the monodomain equation in cardiac electrophysiology.

Published in:

International Journal for Numerical Methods in Biomedical Engineering, 2023, v. 39, n. 2, p. 1, doi. 10.1002/cnm.3666

By:

Lindner, Laura P.;
Gerach, Tobias;
Jahnke, Tobias;
Loewe, Axel;
Weiss, Daniel;
Wieners, Christian

Publication type:

Article

Monitoring the dynamics of acute radiofrequency ablation lesion formation in thin-walled atria – a simultaneous optical and electrical mapping study.

Published in:

Biomedical Engineering / Biomedizinische Technik, 2020, v. 65, n. 3, p. 327, doi. 10.1515/bmt-2019-0013

By:

Pollnow, Stefan;
Schwaderlapp, Gerald;
Loewe, Axel;
Dössel, Olaf

Publication type:

Article

Fibrotic Remodeling during Persistent Atrial Fibrillation: In Silico Investigation of the Role of Calcium for Human Atrial Myofibroblast Electrophysiology.

Published in:

Cells (2073-4409), 2021, v. 10, n. 11, p. 2852, doi. 10.3390/cells10112852

By:

Sánchez, Jorge;
Trenor, Beatriz;
Saiz, Javier;
Dössel, Olaf;
Loewe, Axel

Publication type:

Article

A Review of Healthy and Fibrotic Myocardium Microstructure Modeling and Corresponding Intracardiac Electrograms.

Published in:

Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.908069

By:

Sánchez, Jorge;
Loewe, Axel

Publication type:

Article

Dyssynchronous Left Ventricular Activation is Insufficient for the Breakdown of Wringing Rotation.

Published in:

Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.838038

By:

Gerach, Tobias;
Appel, Stephanie;
Wilczek, Jacek;
Golba, Krzysztof S.;
Jadczyk, Tomasz;
Loewe, Axel

Publication type:

Article

Editorial: Atrial Fibrillation: Technology for Diagnosis, Monitoring, and Treatment.

Published in:

2022

By:

Berenfeld, Omer;
Corino, Valentina D. A.;
Loewe, Axel;
Martínez, Juan Pablo;
Rodriguez Matas, Jose F.

Publication type:

Editorial

A Fully-Coupled Electro-Mechanical Whole-Heart Computational Model: Influence of Cardiac Contraction on the ECG.

Published in:

Frontiers in Physiology, 2021, v. 12, p. 1, doi. 10.3389/fphys.2021.778872

By:

Moss, Robin;
Wülfers, Eike Moritz;
Schuler, Steffen;
Loewe, Axel;
Seemann, Gunnar

Publication type:

Article

Causes of altered ventricular mechanics in hypertrophic cardiomyopathy: an in-silico study.

Published in:

2021

By:

Kovacheva, Ekaterina;
Gerach, Tobias;
Schuler, Steffen;
Ochs, Marco;
Dössel, Olaf;
Loewe, Axel

Publication type:

journal article

Pharmacologic TWIK-Related Acid-Sensitive K+ Channel (TASK-1) Potassium Channel Inhibitor A293 Facilitates Acute Cardioversion of Paroxysmal Atrial Fibrillation in a Porcine Large Animal Model.

Published in:

2020

By:

Wiedmann, Felix;
Beyersdorf, Christoph;
Xiaobo Zhou;
Büscher, Antonius;
Kraft, Manuel;
Nietfeld, Jendrik;
Teo Puig Walz;
Unger, Laura A.;
Loewe, Axel;
Schmack, Bastian;
Ruhparwar, Arjang;
Karck, Matthias;
Thomas, Dierk;
Borggrefe, Martin;
Seemann, Gunnar;
Katus, Hugo A.;
Schmidt, Constanze;
Zhou, Xiaobo;
Walz, Teo Puig

Publication type:

journal article

The reverse mode of the Na+/Ca2+ exchanger contributes to the pacemaker mechanism in rabbit sinus node cells.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-25574-8

By:

Tóth, Noémi;
Loewe, Axel;
Szlovák, Jozefina;
Kohajda, Zsófia;
Bitay, Gergő;
Levijoki, Jouko;
Papp, Julius Gy.;
Varró, András;
Nagy, Norbert

Publication type:

Article

Functional Characterization of a Spectrum of Novel Romano-Ward Syndrome KCNQ1 Variants.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 2, p. 1350, doi. 10.3390/ijms24021350

By:

Rinné, Susanne;
Oertli, Annemarie;
Nagel, Claudia;
Tomsits, Philipp;
Jenewein, Tina;
Kääb, Stefan;
Kauferstein, Silke;
Loewe, Axel;
Beckmann, Britt Maria;
Decher, Niels

Publication type:

Article

Comparison of LGE-MRI and Local Impedance Data Recorded in Human Left Atria.

Published in:

Current Directions in Biomedical Engineering, 2024, v. 10, n. 4, p. 623, doi. 10.1515/cdbme-2024-2153

By:

Stolte, Franziska Sophia;
Martínez Antón, Carmen;
Invers Rubio, Eric;
Guasch, Eduard;
Mont, Lluís;
Dössel, Olaf;
Loewe, Axel

Publication type:

Article

Modeling Human Ventricular Cardiomyocyte Force-Frequency Relationship.

Published in:

Current Directions in Biomedical Engineering, 2024, v. 10, n. 4, p. 212, doi. 10.1515/cdbme-2024-2051

By:

Duhme, Jan-Erik;
Krauß, Jonathan;
Loewe, Axel

Publication type:

Article

Discrepancy Between LGE-MRI and Electro-Anatomical Mapping for Regional Detection of Pathological Atrial Substrate.

Published in:

Current Directions in Biomedical Engineering, 2023, v. 9, n. 1, p. 483, doi. 10.1515/cdbme-2023-1121

By:

Goetz, Christian;
Martínez Díaz, Patricia;
Dössel, Olaf;
Loewe, Axel;
Sánchez, Jorge;
Jadidi, Amir;
Eichenlaub, Martin

Publication type:

Article

Impact of the Right Atrium on Arrhythmia Vulnerability.

Published in:

Current Directions in Biomedical Engineering, 2023, v. 9, n. 1, p. 142, doi. 10.1515/cdbme-2023-1036

By:

Loewe, Axel;
Fitzen, Nikola André;
Martínez Díaz, Patricia;
Dössel, Olaf

Publication type:

Article

Refining the Eikonal Model to Reproduce the Influence of Atrial Tissue Geometry on Conduction Velocity.

Published in:

Current Directions in Biomedical Engineering, 2022, v. 8, n. 2, p. 133, doi. 10.1515/cdbme-2022-1035

By:

Skupien, Nils;
Barrios Espinosa, Cristian;
Dössel, Olaf;
Loewe, Axel

Publication type:

Article

A Large-scale Virtual Patient Cohort to Study ECG Features of Interatrial Conduction Block.

Published in:

Current Directions in Biomedical Engineering, 2022, v. 8, n. 2, p. 97, doi. 10.1515/cdbme-2022-1026

By:

Bender, Jule;
Nagel, Claudia;
Fröhlich, Jonathan;
Wieners, Christian;
Dössel, Olaf;
Loewe, Axel

Publication type:

Article

Classification of Bundle Branch Blocks with QRS Templates Extracted from 12-lead ECGs.

Published in:

Current Directions in Biomedical Engineering, 2021, v. 7, n. 2, p. 582, doi. 10.1515/cdbme-2021-2148

By:

Welle, Hannes;
Nagel, Claudia;
Loewe, Axel;
Mikut, Ralf;
Dössel, Olaf

Publication type:

Article

Sensitivity and Generalization of a Neural Network for Estimating Left Atrial Fibrotic Volume Fractions from the 12-lead ECG.

Published in:

Current Directions in Biomedical Engineering, 2021, v. 7, n. 2, p. 307, doi. 10.1515/cdbme-2021-2078

By:

Nagel, Claudia;
Dössel, Olaf;
Loewe, Axel

Publication type:

Article

Adaptation of the Calcium-dependent Tension Development in Ventricular Cardiomyocytes.

Published in:

Current Directions in Biomedical Engineering, 2021, v. 7, n. 2, p. 251, doi. 10.1515/cdbme-2021-2064

By:

Appel, Stephanie;
Gerach, Tobias;
Dössel, Olaf;
Loewe, Axel

Publication type:

Article

Fluid dynamics in the human heart: Altered vortex formation and wash-out in mitral regurgitation simulations.

Published in:

Current Directions in Biomedical Engineering, 2021, v. 7, n. 2, p. 199, doi. 10.1515/cdbme-2021-2051

By:

Brenneisen, Jochen;
Wentzel, Carlo;
Karwan, Farokh;
Dössel, Olaf;
Loewe, Axel

Publication type:

Article

Separating atrial near fields and atrial far fields in simulated intra-atrial electrograms.

Published in:

Current Directions in Biomedical Engineering, 2021, v. 7, n. 2, p. 175, doi. 10.1515/cdbme-2021-2045

By:

Schicketanz, Leonie;
Unger, Laura Anna;
Sánchez, Jorge;
Dössel, Olaf;
Loewe, Axel

Publication type:

Article

An automate pipeline for generating fiber orientation and region annotation in patient specific atrial models.

Published in:

Current Directions in Biomedical Engineering, 2021, v. 7, n. 2, p. 136, doi. 10.1515/cdbme-2021-2035

By:

Zheng, Tianbao;
Azzolin, Luca;
Sánchez, Jorge;
Dössel, Olaf;
Loewe, Axel

Publication type:

Article

Validating a Numerical Simulation of Human Heart Motion Using Clinical Data.

Published in:

Current Directions in Biomedical Engineering, 2020, v. 6, n. 3, p. 547, doi. 10.1515/cdbme-2020-3140

By:

Müller, Armin;
Kovacheva, Ekaterina;
Fritz, Marc Alexander;
Dössel, Olaf;
Loewe, Axel

Publication type:

Article

Quantification of Interpatient 12-lead ECG Variabilities within a Healthy Cohort.

Published in:

Current Directions in Biomedical Engineering, 2020, v. 6, n. 3, p. 493, doi. 10.1515/cdbme-2020-3127

By:

Nagel, Claudia;
Pilia, Nicolas;
Loewe, Axel;
Dössel, Olaf

Publication type:

Article

Optimization Framework to Identify Constitutive Law Parameters of the Human Heart.

Published in:

Current Directions in Biomedical Engineering, 2020, v. 6, n. 3, p. 95, doi. 10.1515/cdbme-2020-3025

By:

Kovacheva, Ekaterina;
Baron, Lukas;
Schuler, Steffen;
Gerach, Tobias;
Dössel, Olaf;
Loewe, Axel

Publication type:

Article

Modeling of the Human Cerebral Collateral Circulation: Evaluation of the Impact on the Cerebral Perfusion in Case of Ischemic Stroke.

Published in:

Current Directions in Biomedical Engineering, 2019, v. 5, n. 1, p. 533, doi. 10.1515/cdbme-2019-0134

By:

Krames, Lorena;
Daschner, Rosa;
Lutz, Yannick;
Loewe, Axel;
Cattaneo, Giorgio;
Dössel, Olaf

Publication type:

Article

Generation of a Simplified Brain Geometry for the Calculation of Local Cerebral Temperature using a 1D Hemodynamic Model.

Published in:

Current Directions in Biomedical Engineering, 2019, v. 5, n. 1, p. 529, doi. 10.1515/cdbme-2019-0133

By:

Daschner, Rosa;
Krames, Lorena;
Lutz, Yannick;
Loewe, Axel;
Dössel, Olaf;
Cattaneo, Giorgio

Publication type:

Article

Influence of ECG Lead Reduction Techniques for Extracellular Potassium and Calcium Concentration Estimation.

Published in:

Current Directions in Biomedical Engineering, 2019, v. 5, n. 1, p. 69, doi. 10.1515/cdbme-2019-0018

By:

Mesa, María Hernández;
Pilia, Nicolas;
Dössel, Olaf;
Loewe, Axel

Publication type:

Article

Effects of Serum Calcium Changes on the Cardiac Action Potential and the ECG in a Computational Model.

Published in:

Current Directions in Biomedical Engineering, 2018, v. 4, n. 1, p. 251, doi. 10.1515/cdbme-2018-0061

By:

Mesa, María Hernández;
Pilia, Nicolas;
Dössel, Olaf;
Severi, Stefano;
Loewe, Axel

Publication type:

Article

Estimating refractory periods during atrial fibrillation based on electrogram cycle lengths in a heterogeneous simulation setup.

Published in:

Current Directions in Biomedical Engineering, 2017, v. 3, n. 2, p. 317, doi. 10.1515/cdbme-2017-0181

By:

Unger, Laura;
Oesterlein, Tobias;
Seemann, Gunnar;
Dössel, Olaf;
Spector, Peter;
Loewe, Axel

Publication type:

Article

Modelling of patient-specific Purkinje activation based on measured ECGs.

Published in:

Current Directions in Biomedical Engineering, 2017, v. 3, n. 2, p. 171, doi. 10.1515/cdbme-2017-0177

By:

Kahlmann, Willi;
Poremba, Emanuel;
Potyagaylo, Danila;
Dössel, Olaf;
Loewe, Axel

Publication type:

Article

Consensus statement on the credibility assessment of machine learning predictors.

Published in:

Briefings in Bioinformatics, 2025, v. 26, n. 2, p. 1, doi. 10.1093/bib/bbaf100

By:

Aldieri, Alessandra;
Gamage, Thiranja Prasad Babarenda;
Mattina, Antonino Amedeo La;
Loewe, Axel;
Pappalardo, Francesco;
Viceconti, Marco

Publication type:

Article

The Cardiac Pacemaker Story—Fundamental Role of the Na+/Ca2+ Exchanger in Spontaneous Automaticity.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00516

By:

Kohajda, Zsófia;
Loewe, Axel;
Tóth, Noémi;
Varró, András;
Nagy, Norbert

Publication type:

Article

Novel Na+/Ca2+ Exchanger Inhibitor ORM-10962 Supports Coupled Function of Funny-Current and Na+/Ca2+ Exchanger in Pacemaking of Rabbit Sinus Node Tissue.

Published in:

Frontiers in Pharmacology, 2020, p. 1, doi. 10.3389/fphar.2019.01632

By:

Kohajda, Zsófia;
Tóth, Noémi;
Szlovák, Jozefina;
Loewe, Axel;
Bitay, Gergő;
Gazdag, Péter;
Prorok, János;
Jost, Norbert;
Levijoki, Jouko;
Pollesello, Piero;
Papp, Julius Gy.;
Varró, András;
Nagy, Norbert

Publication type:

Article

Impact of effective refractory period personalization on arrhythmia vulnerability in patient-specific atrial computer models.

Published in:

EP: Europace, 2024, v. 26, n. 10, p. 1, doi. 10.1093/europace/euae215

By:

Díaz, Patricia Martínez;
Dasí, Albert;
Goetz, Christian;
Unger, Laura A;
Haas, Annika;
Luik, Armin;
Rodríguez, Blanca;
Dössel, Olaf;
Loewe, Axel

Publication type:

Article

In Silico TRials guide optimal stratification of ATrIal FIbrillation patients to Catheter Ablation and pharmacological medicaTION: the i-STRATIFICATION study.

Published in:

EP: Europace, 2024, v. 26, n. 6, p. 1, doi. 10.1093/europace/euae150

By:

Dasí, Albert;
Nagel, Claudia;
Pope, Michael T B;
Wijesurendra, Rohan S;
Betts, Timothy R;
Sachetto, Rafael;
Loewe, Axel;
Bueno-Orovio, Alfonso;
Rodriguez, Blanca

Publication type:

Article

Differences in atrial substrate localization using late gadolinium enhancement-magnetic resonance imaging, electrogram voltage, and conduction velocity: a cohort study using a consistent anatomical reference frame in patients with persistent atrial fibrillation

Published in:

EP: Europace, 2023, v. 25, n. 9, p. 1, doi. 10.1093/europace/euad278

By:

Nairn, Deborah;
Eichenlaub, Martin;
Müller-Edenborn, Björn;
Huang, Taiyuan;
Lehrmann, Heiko;
Nagel, Claudia;
Azzolin, Luca;
Luongo, Giorgio;
Ventura, Rosa M Figueras;
Forcada, Barbara Rubio;
Colomer, Anna Vallès;
Westermann, Dirk;
Arentz, Thomas;
Dössel, Olaf;
Loewe, Axel;
Jadidi, Amir

Publication type:

Article

Personalized ablation vs. conventional ablation strategies to terminate atrial fibrillation and prevent recurrence.

Published in:

EP: Europace, 2023, v. 25, n. 1, p. 211, doi. 10.1093/europace/euac116

By:

Azzolin, Luca;
Eichenlaub, Martin;
Nagel, Claudia;
Nairn, Deborah;
Sanchez, Jorge;
Unger, Laura;
Dössel, Olaf;
Jadidi, Amir;
Loewe, Axel

Publication type:

Article

Hybrid machine learning to localize atrial flutter substrates using the surface 12-lead electrocardiogram.

Published in:

2022

By:

Luongo, Giorgio;
Vacanti, Gaetano;
Nitzke, Vincent;
Nairn, Deborah;
Nagel, Claudia;
Kabiri, Diba;
Almeida, Tiago P;
Soriano, Diogo C;
Rivolta, Massimo W;
Ng, Ghulam André;
Dössel, Olaf;
Luik, Armin;
Sassi, Roberto;
Schmitt, Claus;
Loewe, Axel

Publication type:

journal article

Cycle length statistics during human atrial fibrillation reveal refractory properties of the underlying substrate: a combined in silico and clinical test of concept study.

Published in:

2021

By:

Unger, Laura A;
Azzolin, Luca;
Nothstein, Mark;
Sánchez, Jorge;
Luik, Armin;
Seemann, Gunnar;
Yeshwant, Srinath;
Oesterlein, Tobias;
Dössel, Olaf;
Schmitt, Claus;
Spector, Peter;
Loewe, Axel

Publication type:

journal article

Influence of left atrial size on P-wave morphology: differential effects of dilation and hypertrophy.

Published in:

2018

By:

Andlauer, Robin;
Seemann, Gunnar;
Baron, Lukas;
Dössel, Olaf;
Kohl, Peter;
Platonov, Pyotr;
Loewe, Axel

Publication type:

journal article

Influence of the earliest right atrial activation site and its proximity to interatrial connections on P-wave morphology.

Published in:

2016

By:

Loewe, Axel;
Krueger, Martin W.;
Holmqvist, Fredrik;
Dössel, Olaf;
Seemann, Gunnar;
Platonov, Pyotr G.

Publication type:

journal article

In-silico assessment of the dynamic effects of amiodarone and dronedarone on human atrial patho-electrophysiology.

Published in:

EP: Europace, 2014, v. 16, p. iv30, doi. 10.1093/europace/euu230

By:

Loewe, Axel;
Lutz, Yannick;
Wilhelms, Mathias;
Sinnecker, Daniel;
Barthel, Petra;
Scholz, Eberhard P.;
Dössel, Olaf;
Schmidt, Georg;
Seemann, Gunnar

Publication type:

Article

Arrhythmic potency of human ether-a-go-go-related gene mutations L532P and N588K in a computational model of human atrial myocytes.

Published in:

2014

By:

Loewe, Axel;
Wilhelms, Mathias;
Fischer, Fathima;
Scholz, Eberhard P;
Dössel, Olaf;
Seemann, Gunnar

Publication type:

journal article

Arrhythmic potency of human ether-à-go-go-related gene mutations L532P and N588K in a computational model of human atrial myocytes.

Published in:

EP: Europace, 2014, v. 16, n. 3, p. 435, doi. 10.1093/europace/eut375

By:

Loewe, Axel;
Wilhelms, Mathias;
Fischer, Fathima;
Scholz, Eberhard P.;
Dössel, Olaf;
Seemann, Gunnar

Publication type:

Article