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LGR5 is expressed by Ewing sarcoma and potentiates Wnt/β-catenin signaling.
Published in:
Frontiers in Oncology, 2013, p. 1, doi. 10.3389/fonc.2013.00081
By:
- Scannell, Christopher A.;
- Pedersen, Elisabeth A.;
- Mosher, Jack T.;
- Krook, Melanie Anne;
- Nicholls, Lauren A.;
- Wilky, Breelyn A.;
- Loeb, David M.;
- Lawlor, Elizabeth R.
Publication type:
Article
LGR5 is expressed by Ewing sarcoma and potentiates Wnt/β-catenin signaling.
Published in:
Frontiers in Oncology, 2013, v. 3, p. 1, doi. 10.3389/fonc.2013.00081
By:
- Scannell, Christopher A.;
- Pedersen, Elisabeth A.;
- Mosher, Jack T.;
- Krook, Melanie Ann;
- Nicholls, Lauren A.;
- Wilky, Breelyn A.;
- Loeb, David M.;
- Lawlor, Elizabeth R.
Publication type:
Article
The role of WT1 in oncogenesis: tumor suppressor or oncogene?
Published in:
2002
By:
- Loeb, David M;
- Sukumar, Saraswati
Publication type:
journal article
A clinically and genomically annotated nerve sheath tumor biospecimen repository.
Published in:
Scientific Data, 2020, v. 7, n. 1, p. 1, doi. 10.1038/s41597-020-0508-5
By:
- Pollard, Kai;
- Banerjee, Jineta;
- Doan, Xengie;
- Wang, Jiawan;
- Guo, Xindi;
- Allaway, Robert;
- Langmead, Shannon;
- Slobogean, Bronwyn;
- Meyer, Christian F.;
- Loeb, David M.;
- Morris, Carol D.;
- Belzberg, Allan J.;
- Blakeley, Jaishri O.;
- Rodriguez, Fausto J.;
- Guinney, Justin;
- Gosline, Sara J. C.;
- Pratilas, Christine A.
Publication type:
Article
IGF1R- and ROR1-Specific CAR T Cells as a Potential Therapy for High Risk Sarcomas.
Published in:
PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0133152
By:
- Huang, Xin;
- Park, Haein;
- Greene, Joseph;
- Pao, James;
- Mulvey, Erin;
- Zhou, Sophia X.;
- Albert, Catherine M.;
- Moy, Fred;
- Sachdev, Deepali;
- Yee, Douglas;
- Rader, Christoph;
- Hamby, Carl V.;
- Loeb, David M.;
- Cairo, Mitchell S.;
- Zhou, Xianzheng
Publication type:
Article
Hypoxia-Sensitive Epigenetic Regulation of an Antisense-Oriented lncRNA Controls WT1 Expression in Myeloid Leukemia Cells.
Published in:
PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0119837
By:
- McCarty, Gregory;
- Loeb, David M.
Publication type:
Article
A Novel Chordoma Xenograft Allows In Vivo Drug Testing and Reveals the Importance of NF-κB Signaling in Chordoma Biology.
Published in:
PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0079950
By:
- Trucco, Matteo M.;
- Awad, Ola;
- Wilky, Breelyn A.;
- Goldstein, Seth D.;
- Huang, Ruili;
- Walker, Robert L.;
- Shah, Preeti;
- Katuri, Varalakshmi;
- Gul, Naheed;
- Zhu, Yuelin J.;
- McCarthy, Edward F.;
- Paz-Priel, Ido;
- Meltzer, Paul S.;
- Austin, Christopher P.;
- Xia, Menghang;
- Loeb, David M.
Publication type:
Article
High ALDH Activity Identifies Chemotherapy-Resistant Ewing's Sarcoma Stem Cells That Retain Sensitivity to EWS-FLI1 Inhibition.
Published in:
PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0013943
By:
- Awad, Ola;
- Yustein, Jason T.;
- Shah, Preeti;
- Gul, Naheed;
- Katuri, Varalakshmi;
- O'Neill, Alison;
- Kong, Yali;
- Brown, Milton L.;
- Toretsky, Jeffrey A.;
- Loeb, David M.
Publication type:
Article
Avelumab in paediatric patients with refractory or relapsed solid tumours: dose-escalation results from an open-label, single-arm, phase 1/2 trial.
Published in:
Cancer Immunology, Immunotherapy, 2022, v. 71, n. 10, p. 2485, doi. 10.1007/s00262-022-03159-8
By:
- Loeb, David M.;
- Lee, Ji Won;
- Morgenstern, Daniel A.;
- Samson, Yvan;
- Uyttebroeck, Anne;
- Lyu, Chuhl Joo;
- Van Damme, An;
- Nysom, Karsten;
- Macy, Margaret E.;
- Zorzi, Alexandra P.;
- Xiong, Julia;
- Pollert, Petra;
- Joerg, Ingrid;
- Vugmeyster, Yulia;
- Ruisi, Mary;
- Kang, Hyoung Jin
Publication type:
Article
Remission of severe autoimmune enteropathy after treatment with high-dose cyclophosphamide.
Published in:
2003
By:
- Oliva-Hemker, Maria M;
- Loeb, David M;
- Abraham, Susan C;
- Lederman, Howard M
Publication type:
journal article
Targeted therapy for soft tissue sarcomas in adolescents and young adults.
Published in:
Adolescent Health, Medicine & Therapeutics, 2017, v. 8, p. 41, doi. 10.2147/AHMT.S70377
By:
- Steppan, Diana A.;
- Pratilas, Christine A.;
- Loeb, David M.
Publication type:
Article
Delayed Solid Tumor Presentations in Adolescent and Young Adults Patients in the Bronx.
Published in:
Journal of Adolescent & Young Adult Oncology, 2024, v. 13, n. 2, p. 361, doi. 10.1089/jayao.2023.0078
By:
- Offenbacher, Rachel;
- Norris, Sarah;
- Loeb, David M.;
- Levy, Adam
Publication type:
Article
VISTA Emerges as a Promising Target against Immune Evasion Mechanisms in Medulloblastoma.
Published in:
Cancers, 2024, v. 16, n. 15, p. 2629, doi. 10.3390/cancers16152629
By:
- Muñoz Perez, Natalia;
- Pensabene, Juliana M.;
- Galbo Jr., Phillip M.;
- Sadeghipour, Negar;
- Xiu, Joanne;
- Moziak, Kirsten;
- Yazejian, Rita M.;
- Welch, Rachel L.;
- Bell, W. Robert;
- Sengupta, Soma;
- Aulakh, Sonikpreet;
- Eberhart, Charles G.;
- Loeb, David M.;
- Eskandar, Emad;
- Zheng, Deyou;
- Zang, Xingxing;
- Martin, Allison M.
Publication type:
Article
Results of a Randomized, Double-Blinded, Placebo-Controlled, Phase 2.5 Study of Saracatinib (AZD0530), in Patients with Recurrent Osteosarcoma Localized to the Lung.
Published in:
Sarcoma, 2020, p. 1, doi. 10.1155/2020/7935475
By:
- Baird, Kristin;
- Glod, John;
- Steinberg, Seth M.;
- Reinke, Denise;
- Pressey, Joseph G.;
- Mascarenhas, Leo;
- Federman, Noah;
- Marina, Neyssa;
- Chawla, Sant;
- Lagmay, Joanne P.;
- Goldberg, John;
- Milhem, Mohammed;
- Loeb, David M.;
- Butrynski, James E.;
- Turpin, Brian;
- Staddon, Arthur;
- Spunt, Sheri L.;
- Jones, Robin L.;
- Rodler, Eve T.;
- Schuetze, Scott M.
Publication type:
Article
Nerve growth factor induced stimulation of Ras requires Trk interaction with Shc but does not involve phosphoinositide 3-OH kinase.
Published in:
Oncogene, 1998, v. 17, n. 6, p. 691, doi. 10.1038/sj.onc.1201980
By:
- Hallberg, Bengt;
- Ashcroft, Margaret;
- Loeb, David M;
- Kaplan, David R;
- Downward, Julian
Publication type:
Article
Caspase-8 expression is predictive of tumour response to death receptor 5 agonist antibody in Ewing's sarcoma.
Published in:
2015
By:
- Kang, Zhigang;
- Goldstein, Seth D;
- Yu, Yunkai;
- Meltzer, Paul S;
- Loeb, David M;
- Cao, Liang
Publication type:
journal article
Tumor Dosimetry and Response for 153Sm-Ethylenediamine Tetramethylene Phosphonic Acid Therapy of High-Risk Osteosarcoma.
Published in:
Journal of Nuclear Medicine, 2012, v. 53, n. 2, p. 215, doi. 10.2967/jnumed.111.096677
By:
- Senthamizhchelvan, Srinivasan;
- Hobbs, Robert F.;
- Hong Song;
- Frey, Eric C.;
- Zhe Zhang;
- Armour, Elwood;
- Wahl, Richard L.;
- Loeb, David M.;
- Sgouros, George
Publication type:
Article
A phase II trial evaluating the feasibility of adding bevacizumab to standard osteosarcoma therapy.
Published in:
International Journal of Cancer, 2017, v. 141, n. 7, p. 1469, doi. 10.1002/ijc.30841
By:
- Navid, Fariba;
- Santana, Victor M.;
- Neel, Michael;
- McCarville, M. Beth;
- Shulkin, Barry L.;
- Wu, Jianrong;
- Billups, Catherine A.;
- Mao, Shenghua;
- Daryani, Vinay M.;
- Stewart, Clinton F.;
- Kunkel, Michelle;
- Smith, Wendene;
- Ward, Deborah;
- Pappo, Alberto S.;
- Bahrami, Armita;
- Loeb, David M.;
- Reikes Willert, Jennifer;
- Rao, Bhaskar N.;
- Daw, Najat C.
Publication type:
Article
Three-dimensional in vitro modeling of malignant bone disease recapitulates experimentally accessible mechanisms of osteoinhibition.
Published in:
Cell Death & Disease, 2018, v. 9, n. 12, p. 1, doi. 10.1038/s41419-018-1203-8
By:
- McNeill, Eoin P.;
- Reese, Robert W.;
- Tondon, Abishek;
- Clough, Bret H.;
- Pan, Simin;
- Froese, Jeremiah;
- Palmer, Daniel;
- Krause, Ulf;
- Loeb, David M.;
- Kaunas, Roland;
- Gregory, Carl A.
Publication type:
Article
A multicenter report on the safety and efficacy of plerixafor based stem cell mobilization in children with malignant disorders.
Published in:
Transfusion, 2021, v. 61, n. 3, p. 894, doi. 10.1111/trf.16260
By:
- Bhunia, Nabanita;
- Abu‐Arja, Rolla;
- Stanek, Joseph R.;
- Mehyar, Lubna S.;
- Shaw, Peter J.;
- Kang, Hyoung Jin;
- Stein, Jerry;
- O'Brien, Tracey A.;
- Roberts, Catherine H.;
- Lee, Anselm Chi‐wai;
- Loeb, David M.;
- Ozkaynak, Mehmet F.;
- Dalal, Jignesh D.;
- Strahlendorf, Caron;
- Goyal, Rakesh K.;
- Shenoy, Shalini S.;
- Rangarajan, Hemalatha G.
Publication type:
Article
Atypical hemolytic uremic syndrome during induction chemotherapy in neuroblastoma, a rare phenomenon or common congenital predisposition?
Published in:
Pediatric Blood & Cancer, 2024, v. 71, n. 9, p. 1, doi. 10.1002/pbc.31175
By:
- Davitt, Meghan;
- Offenbacher, Rachel;
- Lee, Michelle A.;
- Loeb, David M.;
- Manwani, Deepa;
- Mitchell, William;
- Weiser, Daniel A.
Publication type:
Article
Pembrolizumab as maintenance therapy for malignant rhabdoid tumor.
Published in:
Pediatric Blood & Cancer, 2022, v. 69, n. 10, p. 1, doi. 10.1002/pbc.29660
By:
- Offenbacher, Rachel;
- Fabish, Lara;
- Oliver‐Krasinski, Jennifer;
- Loeb, David M.;
- Baker, Alissa
Publication type:
Article
SARS‐CoV‐2 as a mimicker of pulmonary metastasis in osteosarcoma.
Published in:
Pediatric Blood & Cancer, 2022, v. 69, n. 6, p. 1, doi. 10.1002/pbc.29435
By:
- Offenbacher, Rachel;
- Fabish, Lara;
- Baker, Alissa;
- Loeb, David M.
Publication type:
Article
Delayed presentations of pediatric solid tumors at a tertiary care hospital in the Bronx due to COVID‐19.
Published in:
Pediatric Blood & Cancer, 2021, v. 68, n. 2, p. 1, doi. 10.1002/pbc.28615
By:
- Offenbacher, Rachel;
- Knoll, Miriam A.;
- Loeb, David M.
Publication type:
Article
Phase II trial of gemcitabine and nab-paclitaxel in patients with recurrent Ewing sarcoma: A report from the National Pediatric Cancer Foundation.
Published in:
2020
By:
- Oesterheld, Javier E.;
- Reed, Damon R.;
- Setty, Bhuvana A.;
- Isakoff, Michael S.;
- Thompson, Patrick;
- Yin, Hong;
- Hayashi, Masanori;
- Loeb, David M.;
- Smith, Tiffany;
- Makanji, Rikesh;
- Fridley, Brooke L.;
- Wagner, Lars M.
Publication type:
journal article
Consensus and controversies regarding the treatment of rhabdomyosarcoma.
Published in:
2018
By:
- Borinstein, Scott C.;
- Steppan, Diana;
- Hayashi, Masanori;
- Loeb, David M.;
- Isakoff, Michael S.;
- Binitie, Odion;
- Brohl, Andrew S.;
- Bridge, Julia A.;
- Stavas, Mark;
- Shinohara, Eric T.;
- Meyer, William H.;
- Reed, Damon R.;
- Wagner, Lars M.
Publication type:
journal article
Targeted Treatment in Sarcoma Patients.
Published in:
Clinical Advances in Hematology & Oncology, 2011, v. 9, n. 12, p. 934
By:
- Loeb, David M.
Publication type:
Article
Treatment pathway of bone sarcoma in children, adolescents, and young adults.
Published in:
2017
By:
- Reed, Damon R.;
- Hayashi, Masanori;
- Wagner, Lars;
- Binitie, Odion;
- Steppan, Diana A.;
- Brohl, Andrew S.;
- Shinohara, Eric T.;
- Bridge, Julia A.;
- Loeb, David M.;
- Borinstein, Scott C.;
- Isakoff, Michael S.
Publication type:
journal article
Phase 2 study of dasatinib in patients with alveolar soft part sarcoma, chondrosarcoma, chordoma, epithelioid sarcoma, or solitary fibrous tumor.
Published in:
2017
By:
- Schuetze, Scott M.;
- Bolejack, Vanessa;
- Choy, Edwin;
- Ganjoo, Kristen N.;
- Staddon, Arthur P.;
- Chow, Warren A.;
- Tawbi, Hussein A.;
- Samuels, Brian L.;
- Patel, Shreyaskumar R.;
- Mehren, Margaret;
- D'Amato, Gina;
- Leu, Kirsten M.;
- Loeb, David M.;
- Forscher, Charles A.;
- Milhem, Mohammed M.;
- Rushing, Daniel A.;
- Lucas, David R.;
- Chugh, Rashmi;
- Reinke, Denise K.;
- Baker, Laurence H.
Publication type:
journal article
Highly personalized detection of minimal Ewing sarcoma disease burden from plasma tumor DNA.
Published in:
2016
By:
- Hayashi, Masanori;
- Chu, David;
- Meyer, Christian F.;
- Llosa, Nicolas J.;
- McCarty, Gregory;
- Morris, Carol D.;
- Levin, Adam S.;
- Wolinsky, Jean‐Paul;
- Albert, Catherine M.;
- Steppan, Diana A.;
- Park, Ben Ho;
- Loeb, David M.;
- Wolinsky, Jean-Paul
Publication type:
journal article
SARC009: Phase 2 study of dasatinib in patients with previously treated, high-grade, advanced sarcoma.
Published in:
2016
By:
- Schuetze, Scott M.;
- Wathen, J. Kyle;
- Lucas, David R.;
- Choy, Edwin;
- Samuels, Brian L.;
- Staddon, Arthur P.;
- Ganjoo, Kristen N.;
- von Mehren, Margaret;
- Chow, Warren A.;
- Loeb, David M.;
- Tawbi, Hussein A.;
- Rushing, Daniel A.;
- Patel, Shreyaskumar R.;
- Thomas, Dafydd G.;
- Chugh, Rashmi;
- Reinke, Denise K.;
- Baker, Laurence H.
Publication type:
journal article
Tandem Dosing of Samarium-153 Ethylenediamine Tetramethylene Phosphoric Acid With Stem Cell Support for Patients With High-Risk Osteosarcoma.
Published in:
Cancer (0008543X), 2010, v. 116, n. 23, p. 5470, doi. 10.1002/cncr.25518
By:
- Loeb, David M.;
- Hobbs, Robert F.;
- Okoli, Amarachukwu;
- Chen, Allen R.;
- Cho, Steve;
- Srinivasan, Senthamizhchelvan;
- Sgouros, George;
- Shokek, Ori;
- Wharam Jr, Moody D.;
- Scott, Tammy;
- Schwartz, Cindy L.
Publication type:
Article
Dose-finding study of 153Sm-EDTMP in patients with poor-prognosis osteosarcoma.
Published in:
2009
By:
- Loeb DM;
- Garrett-Mayer E;
- Hobbs RF;
- Prideaux AR;
- Sgouros G;
- Shokek O;
- Wharam MD Jr;
- Scott T;
- Schwartz CL;
- Loeb, David M;
- Garrett-Mayer, Elizabeth;
- Hobbs, Robert F;
- Prideaux, Andrew R;
- Sgouros, George;
- Shokek, Ori;
- Wharam, Moody D Jr;
- Scott, Tammy;
- Schwartz, Cindy L
Publication type:
journal article
Dose-finding Study of 153Sm-EDTMP in Patients With Poor-prognosis Osteosarcoma.
Published in:
Cancer (0008543X), 2009, v. 115, n. 11, p. 2514, doi. 10.1002/cncr.24286
By:
- Loeb, David M.;
- ElizabethvGarrett-Mayer;
- Hobbs, Robert F.;
- Prideaux, Andrew P.;
- Sgouros, George;
- Shokek, Ori;
- Wharam Jr., Moody D.;
- Scott, Tammy;
- Schwartz, Cindy L.
Publication type:
Article
Cardiac metastasis and hypertrophic osteoarthropathy in recurrent infantile fibrosarcoma.
Published in:
Pediatric Blood & Cancer, 2012, v. 59, n. 1, p. 179, doi. 10.1002/pbc.23321
By:
- Shah, Nirali N.;
- Price, Mitchell R.;
- Loeb, David M.
Publication type:
Article
WT1 expression at diagnosis does not predict survival in pediatric aml: A report from the Children's Oncology Group.
Published in:
Pediatric Blood & Cancer, 2009, v. 53, n. 6, p. 1136, doi. 10.1002/pbc.22142
By:
- Noronha, Suzie A.;
- Farrar, Jason E.;
- Alonzo, Todd A.;
- Gerbing, Robert B.;
- Lacayo, Norman J.;
- Dahl, Gary V.;
- Ravindranath, Yaddanapudi;
- Arceci, Robert J.;
- Loeb, David M.
Publication type:
Article
Intravenous pentamidine is effective as second line Pneumocystis pneumonia prophylaxis in pediatric oncology patients.
Published in:
Pediatric Blood & Cancer, 2008, v. 50, n. 4, p. 779, doi. 10.1002/pbc.21287
By:
- Kim, Su Young;
- Dabb, Alix A.;
- Glenn, Donald J.;
- Snyder, Kristen M.;
- Chuk, Meredith K.;
- Loeb, David M.
Publication type:
Article
Treatment of hepatitis-associated aplastic anemia with high-dose cyclophosphamide.
Published in:
Pediatric Blood & Cancer, 2007, v. 49, n. 7, p. 947, doi. 10.1002/pbc.21143
By:
- Savage, William J.;
- DeRusso, Patricia A.;
- Resar, Linda M.;
- Chen, Allen R.;
- Higman, Meghan A.;
- Loeb, David M.;
- Jones, Richard J.;
- Brodsky, Robert A.
Publication type:
Article
Significant responses to platinum-based chemotherapy in renal medullary carcinoma.
Published in:
Pediatric Blood & Cancer, 2005, v. 44, n. 4, p. 407, doi. 10.1002/pbc.20292
By:
- Strouse, John J.;
- Spevak, Melissa;
- Mack, A. Kyle;
- Arceci, Robert J.;
- Small, Donald;
- Loeb, David M.
Publication type:
Article
A Purine Analog-Sensitive Protein Kinase Activity Associates with Trk Nerve Growth Factor Receptors.
Published in:
Journal of Neurochemistry, 1993, v. 61, n. 2, p. 664, doi. 10.1111/j.1471-4159.1993.tb02171.x
By:
- Volonté, Cinzia;
- Loeb, David M.;
- Greene, Lloyd A.
Publication type:
Article
Cell-Cycle Dependent Expression of a Translocation-Mediated Fusion Oncogene Mediates Checkpoint Adaptation in Rhabdomyosarcoma.
Published in:
PLoS Genetics, 2014, v. 10, n. 1, p. 1, doi. 10.1371/journal.pgen.1004107
By:
- Kikuchi, Ken;
- Hettmer, Simone;
- Aslam, M. Imran;
- Michalek, Joel E.;
- Laub, Wolfram;
- Wilky, Breelyn A.;
- Loeb, David M.;
- Rubin, Brian P.;
- Wagers, Amy J.;
- Keller, Charles
Publication type:
Article
An evolutionary framework for treating pediatric sarcomas.
Published in:
2020
By:
- Reed, Damon R.;
- Metts, Jonathan;
- Pressley, Mariyah;
- Fridley, Brooke L.;
- Hayashi, Masanori;
- Isakoff, Michael S.;
- Loeb, David M.;
- Makanji, Rikesh;
- Roberts, Ryan D.;
- Trucco, Matteo;
- Wagner, Lars M.;
- Alexandrow, Mark G.;
- Gatenby, Robert A.;
- Brown, Joel S.
Publication type:
journal article
Generation of chordoma cell line JHC7 and the identification of Brachyury as a novel molecular target.
Published in:
Journal of Neurosurgery, 2011, v. 115, n. 4, p. 760, doi. 10.3171/2011.5.JNS11185
By:
- HSU, WESLEY;
- MOHYELDIN, AHMED;
- SHAH, SAGAR R.;
- AP RHYS, COLETTE M.;
- JOHNSON, LAKESHA F.;
- SEDORA-ROMAN, NEDA I.;
- KOSZTOWSKI, THOMAS A.;
- AWAD, OLA A.;
- MCCARTHY, EDWARD F.;
- LOEB, DAVID M.;
- WOLINSKY, JEAN-PAUL;
- GOKASLAN, ZIYA L.;
- QUIÑONES-HINOJOSA, ALFREDO
Publication type:
Article

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