Works by LoRusso, Patricia

Results: 136

Bioavailability and pharmacokinetics of the investigational anticancer agent XK469 (NSC 698215) in rats following oral and intravenous administration.

Published in:

2005

By:

Boinpally, Ramesh;
Sen-Lin Zhou;
LoRusso, Patricia;
Parchment, Ralph;
Boinpally, Ramesh R;
Zhou, Sen-Lin;
LoRusso, Patricia M;
Parchment, Ralph E

Publication type:

journal article

A pharmacodynamically guided dose selection of PF-00337210 in a phase I study in patients with advanced solid tumors.

Published in:

2016

By:

Bruce, Justine;
LoRusso, Patricia;
Goncalves, Priscila;
Heath, Elisabeth;
Sadowski, Elizabeth;
Shalinsky, David;
Zhang, Yanwei;
Traynor, Anne;
Breazna, Aurora;
Ricart, Alejandro;
Tortorici, Michael;
Liu, Glenn;
Bruce, Justine Yang;
LoRusso, Patricia M;
Goncalves, Priscila H;
Heath, Elisabeth I;
Shalinsky, David R;
Traynor, Anne M;
Ricart, Alejandro D

Publication type:

journal article

Lack of food effect on single-dose pharmacokinetics of brivanib, and safety and efficacy following multiple doses in subjects with advanced or metastatic solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1377, doi. 10.1007/s00280-011-1603-2

By:

LoRusso, Patricia;
Shapiro, Geoffrey;
Hurwitz, Herbert;
Pilat, Mary;
Chemidlin, Janice;
Kollia, Georgia;
Syed, Shariq;
Fischer, Bruce;
Masson, Eric

Publication type:

Article

Dose-escalating and pharmacological study of bortezomib in adult cancer patients with impaired renal function: a National Cancer Institute Organ Dysfunction Working Group Study.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1439, doi. 10.1007/s00280-011-1637-5

By:

Leal, Ticiana;
Remick, Scot;
Takimoto, Chris;
Ramanathan, Ramesh;
Davies, Angela;
Egorin, Merrill;
Hamilton, Anne;
LoRusso, Patricia;
Shibata, Stephen;
Lenz, Heinz-Josef;
Mier, James;
Sarantopoulos, John;
Mani, Sridhar;
Wright, John;
Ivy, S.;
Neuwirth, Rachel;
Moltke, Lisa;
Venkatakrishnan, Karthik;
Mulkerin, Daniel

Publication type:

Article

Sunitinib in combination with paclitaxel plus carboplatin in patients with advanced solid tumors: phase I study results.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 3, p. 703, doi. 10.1007/s00280-010-1536-1

By:

Heath, Elisabeth;
Blumenschein, George;
Cohen, Roger;
LoRusso, Patricia;
LoConte, Noelle;
Kim, Sindy;
Ruiz-Garcia, Ana;
Chao, Richard;
Wilding, George

Publication type:

Article

4,4′-Dihydroxybenzophenone-2,4-dinitrophenylhydrazone (A-007): a topical treatment for cutaneous metastases from malignant cancers.

Published in:

2006

By:

Eilender, David;
LoRusso, Patricia;
Thomas, Leonard;
McCormick, Catherine;
Rodgers, Andrew H.;
Hooper, Catherine L.;
Tornyos, Karl;
Krementz, Edward T.;
Parker, Steven;
Morgan, Lee Roy

Publication type:

Editorial

Metabolic profile of XK469 (2( R)-[4-(7-chloro-2-quinoxalinyl)oxyphenoxy]-propionic acid; NSC698215) in patients and in vitro: low potential for active or toxic metabolites or for drug–drug interactions.

Published in:

Cancer Chemotherapy & Pharmacology, 2005, v. 56, n. 4, p. 351, doi. 10.1007/s00280-004-0962-3

By:

Anderson, Lawrence W.;
Collins, Jerry M.;
Klecker, Raymond W.;
Katki, Aspandiar G.;
Parchment, Ralph E.;
Boinpally, Ramesh R.;
LoRusso, Patricia M.;
Ivy, S. Percy

Publication type:

Article

In vitro and in vivo effects of acetyldinaline on murine megakaryocytopoiesis.

Published in:

2004

By:

Volpe, Donna A.;
LoRusso, Patricia M.;
Foster, Brenda J.;
Parchment, Ralph E.

Publication type:

journal article

Quantifying the impact of the COVID-19 pandemic on cancer center clinical trial operations.

Published in:

JNCI Cancer Spectrum, 2023, v. 7, n. 4, p. 1, doi. 10.1093/jncics/pkad048

By:

George, Thomas J;
Lin, Tara L;
Bentz, Tricia Adrales;
Grant, Stefan;
Houston, Collette M;
Nashawati, Melissa A;
Pappu, Bhanu;
Peck, Helen;
Zafirovski, Alex;
Kerstann, Kimberly;
LoRusso, Patricia;
Schnatterly, Anne;
Hofacker, Janie;
Cameron, Kendra;
Honeycutt, Hailey;
Werner, Theresa L

Publication type:

Article

An International Phase 2 Study of Pazopanib in Progressive and Metastatic Thyroglobulin Antibody Negative Radioactive Iodine Refractory Differentiated Thyroid Cancer.

Published in:

Thyroid, 2020, v. 30, n. 9, p. 1254, doi. 10.1089/thy.2019.0269

By:

Bible, Keith C.;
Menefee, Michael E.;
Lin, Chia-Chi (Josh);
Millward, Michael J.;
Maples, William J.;
Goh, Boon Cher;
Karlin, Nina J.;
Kane, Madeleine A.;
Adkins, Douglas R.;
Molina, Julian R.;
Donehower, Ross C.;
Lim, Wan-Teck;
Flynn, Patrick J.;
Richardson, Ronald L.;
Traynor, Anne M.;
Rubin, Joseph;
LoRusso, Patricia M.;
Smallridge, Robert C.;
Burton, Jill K.;
Suman, Vera J.

Publication type:

Article

Pre-clinical animal models are poor predictors of human toxicities in phase 1 oncology clinical trials.

Published in:

2020

By:

Atkins, Johnique T.;
George, Goldy C.;
Hess, Kenneth;
Marcelo-Lewis, Kathrina L.;
Yuan, Ying;
Borthakur, Gautam;
Khozin, Sean;
LoRusso, Patricia;
Hong, David S.

Publication type:

journal article

Safety and pharmacokinetics of MM-302, a HER2-targeted antibody-liposomal doxorubicin conjugate, in patients with advanced HER2-positive breast cancer: a phase 1 dose-escalation study.

Published in:

British Journal of Cancer, 2018, v. 119, n. 9, p. 1086, doi. 10.1038/s41416-018-0235-2

By:

Munster, Pamela;
Krop, Ian E.;
LoRusso, Patricia;
Ma, Cynthia;
Siegel, Barry A.;
Shields, Anthony F.;
Molnár, István;
Wickham, Thomas J.;
Reynolds, Joseph;
Campbell, Karen;
Hendriks, Bart S.;
Adiwijaya, Bambang S.;
Geretti, Elena;
Moyo, Victor;
Miller, Kathy D.

Publication type:

Article

Safety and pharmacokinetics of MM-302, a HER2-targeted antibody-liposomal doxorubicin conjugate, in patients with advanced HER2-positive breast cancer: a phase 1 dose-escalation study.

Published in:

2018

By:

Munster, Pamela;
Krop, Ian E;
LoRusso, Patricia;
Ma, Cynthia;
Siegel, Barry A;
Shields, Anthony F;
Molnár, István;
Wickham, Thomas J;
Reynolds, Joseph;
Campbell, Karen;
Hendriks, Bart S;
Adiwijaya, Bambang S;
Geretti, Elena;
Moyo, Victor;
Miller, Kathy D

Publication type:

journal article

Impact of race on dose selection of molecular-targeted agents in early-phase oncology trials.

Published in:

2018

By:

Yokota, Tomoya;
Bendell, Johanna;
LoRusso, Patricia;
Tsushima, Takahiro;
Desai, Ved;
Kenmotsu, Hirotsugu;
Watanabe, Junichiro;
Ono, Akira;
Murugesan, Bhavani;
Silva, Joseph;
Naito, Tateaki;
Greenberg, Jonathan;
Kumar, Prasanna;
Wang, Yibin;
Jikoh, Takahiro;
Shiga, Ryota;
Hyman, David M.;
Ho, Alan Loh;
Spriggs, David R.;
Schwartz, Gary K.

Publication type:

journal article

Phase 1 trials of PEGylated recombinant human hyaluronidase PH20 in patients with advanced solid tumours.

Published in:

British Journal of Cancer, 2018, v. 118, n. 2, p. 153, doi. 10.1038/bjc.2017.327

By:

Infante, Jeffrey R;
Korn, Ronald L;
Rosen, Lee S;
LoRusso, Patricia;
Dychter, Samuel S;
Zhu, Joy;
Maneval, Daniel C;
Jiang, Ping;
Shepard, H Michael;
Frost, Gregory;
Von Hoff, Daniel D;
Borad, Mitesh J;
Ramanathan, Ramesh K

Publication type:

Article

Phase 1 trials of PEGylated recombinant human hyaluronidase PH20 in patients with advanced solid tumours.

Published in:

2018

By:

Infante, Jeffrey R;
Korn, Ronald L;
Rosen, Lee S;
LoRusso, Patricia;
Dychter, Samuel S;
Zhu, Joy;
Maneval, Daniel C;
Jiang, Ping;
Shepard, H Michael;
Frost, Gregory;
Von Hoff, Daniel D;
Borad, Mitesh J;
Ramanathan, Ramesh K

Publication type:

corrected article

Phase 1 trials of PEGylated recombinant human hyaluronidase PH20 in patients with advanced solid tumours.

Published in:

2017

By:

Infante, Jeffrey R;
Korn, Ronald L;
Rosen, Lee S;
LoRusso, Patricia;
Dychter, Samuel S;
Zhu, Joy;
Maneval, Daniel C;
Jiang, Ping;
Shepard, H Michael;
Frost, Gregory;
Von Hoff, Daniel D;
Borad, Mitesh J;
Ramanathan, Ramesh K

Publication type:

journal article

Erlotinib therapy for central nervous system hemangioblastomatosis associated with von Hippel-Lindau disease: a case report.

Published in:

2011

By:

Rogers, Lisa;
LoRusso, Patricia;
Nadler, Paul;
Malik, Ghaus;
Shields, Anthony;
Kaelin, William

Publication type:

Report

Icrucumab, a fully human monoclonal antibody against the vascular endothelial growth factor receptor-1, in the treatment of patients with advanced solid malignancies: a Phase 1 study.

Published in:

Investigational New Drugs, 2014, v. 32, n. 2, p. 303, doi. 10.1007/s10637-013-9998-8

By:

LoRusso, Patricia;
Krishnamurthi, Smitha;
Youssoufian, Hagop;
Hall, Nancy;
Fox, Floyd;
Dontabhaktuni, Aruna;
Grebennik, Dmitri;
Remick, Scot

Publication type:

Article

Phase 1 dose-escalation, pharmacokinetic, and cerebrospinal fluid distribution study of TAK-285, an investigational inhibitor of EGFR and HER2.

Published in:

Investigational New Drugs, 2014, v. 32, n. 1, p. 160, doi. 10.1007/s10637-013-9988-x

By:

LoRusso, Patricia;
Venkatakrishnan, Karthik;
Chiorean, E.;
Noe, Dennis;
Wu, Jing-Tao;
Sankoh, Serap;
Corvez, Maria;
Sausville, Edward

Publication type:

Article

A Phase 1 dose-escalation study of the safety and pharmacokinetics of once-daily oral foretinib, a multi-kinase inhibitor, in patients with solid tumors.

Published in:

Investigational New Drugs, 2013, v. 31, n. 3, p. 742, doi. 10.1007/s10637-012-9881-z

By:

Shapiro, Geoffrey;
McCallum, Stewart;
Adams, Laurel;
Sherman, Laurie;
Weller, Steve;
Swann, Suzanne;
Keer, Harold;
Miles, Dale;
Müller, Thomas;
LoRusso, Patricia

Publication type:

Article

Phase 1, open-label study of MEDI-547 in patients with relapsed or refractory solid tumors.

Published in:

Investigational New Drugs, 2013, v. 31, n. 1, p. 77, doi. 10.1007/s10637-012-9801-2

By:

Annunziata, Christina M.;
Kohn, Elise C.;
LoRusso, Patricia;
Houston, Nicole D.;
Coleman, Robert L.;
Buzoianu, Manuela;
Robbie, Gabriel;
Lechleider, Robert

Publication type:

Article

A phase I pharmacokinetic and safety evaluation of oral pazopanib dosing administered as crushed tablet or oral suspension in patients with advanced solid tumors.

Published in:

Investigational New Drugs, 2012, v. 30, n. 4, p. 1566, doi. 10.1007/s10637-011-9725-2

By:

Heath, Elisabeth;
Forman, Karen;
Malburg, Lisa;
Gainer, Shelby;
Suttle, A.;
Adams, Laurel;
Ball, Howard;
LoRusso, Patricia

Publication type:

Article

A Comparison of the pharmacokinetics of the anticancer MET inhibitor foretinib free base tablet formulation to bisphosphate salt capsule formulation in patients with solid tumors.

Published in:

Investigational New Drugs, 2012, v. 30, n. 1, p. 327, doi. 10.1007/s10637-010-9536-x

By:

Naing, Aung;
Kurzrock, Razelle;
Adams, Laurel;
Kleha, Joseph;
Laubscher, Kevin;
Bonate, Peter;
Weller, Steven;
Fitzgerald, Colleen;
Xu, Yanmei;
LoRusso, Patricia

Publication type:

Article

Phase I study of oral irinotecan as a single-agent and given sequentially with capecitabine.

Published in:

Investigational New Drugs, 2012, v. 30, n. 1, p. 290, doi. 10.1007/s10637-010-9528-x

By:

Goff, Laura;
Benson, Al;
LoRusso, Patricia;
Tan, Antoinette;
Berlin, Jordan;
Denis, Louis;
Benner, Rebecca;
Yin, Donghua;
Rothenberg, Mace

Publication type:

Article

Cediranib in combination with various anticancer regimens: results of a phase I multi-cohort study.

Published in:

Investigational New Drugs, 2011, v. 29, n. 6, p. 1395, doi. 10.1007/s10637-010-9484-5

By:

LoRusso, Patricia;
Shields, Anthony;
Gadgeel, Shirish;
Vaishampayan, Ulka;
Guthrie, Tina;
Puchalski, Thomas;
Xu, John;
Liu, Qi

Publication type:

Article

A phase 1 study of BMS-275183, a novel oral analogue of paclitaxel given on a daily schedule to patients with advanced malignancies.

Published in:

Investigational New Drugs, 2011, v. 29, n. 6, p. 1426, doi. 10.1007/s10637-010-9498-z

By:

Heath, Elisabeth;
LoRusso, Patricia;
Ramalingam, Suresh;
Awada, Ahmad;
Egorin, Merrill;
Besse-Hamer, Tatiana;
Cardoso, Fatima;
Valdivieso, Manuel;
Has, Teresa;
Alland, Leila;
Zhou, Xiaofei;
Belani, Chandra

Publication type:

Article

A phase I study of ispinesib, a kinesin spindle protein inhibitor, administered weekly for three consecutive weeks of a 28-day cycle in patients with solid tumors.

Published in:

Investigational New Drugs, 2011, v. 29, n. 3, p. 467, doi. 10.1007/s10637-009-9374-x

By:

Burris, Howard;
Jones, Suzanne;
Williams, Daphne;
Kathman, Steven;
Hodge, Jeffrey;
Pandite, Lini;
Ho, Peter;
Boerner, Scott;
LoRusso, Patricia

Publication type:

Article

Phase I dose-escalation study of the thioxanthone SR271425 administered intravenously once every 3 weeks in patients with advanced malignancies.

Published in:

Investigational New Drugs, 2008, v. 26, n. 4, p. 347, doi. 10.1007/s10637-008-9135-2

By:

Priscila Goncalves;
Francine High;
Paul Juniewicz;
Gareth Shackleton;
Jing Li;
Scott Boerner;
Patricia LoRusso

Publication type:

Article

Effect of coadministration of ketoconazole, a strong CYP3A4 inhibitor, on pharmacokinetics and tolerability of motesanib diphosphate (AMG 706) in patients with advanced solid tumors.

Published in:

Investigational New Drugs, 2008, v. 26, n. 5, p. 455, doi. 10.1007/s10637-008-9144-1

By:

Patricia LoRusso;
Elisabeth Heath;
Jesse McGreivy;
Yu-Nien Sun;
Rebeca Melara;
Lucy Yan;
Lisa Malburg;
Megan Ingram;
Jeffrey Wiezorek;
Li Chen;
Mary Pilat

Publication type:

Article

Phase I clinical evaluation of ZD6126, a novel vascular-targeting agent, in patients with solid tumors.

Published in:

Investigational New Drugs, 2008, v. 26, n. 2, p. 159, doi. 10.1007/s10637-008-9112-9

By:

Patricia LoRusso;
Shirish Gadgeel;
Antoinette Wozniak;
Alan Barge;
Helen Jones;
Zachary DelProposto;
Pamela DeLuca;
Jeffrey Evelhoch;
Scott Boerner;
Catherine Wheeler

Publication type:

Article

A phase 1 study of SNS-032 (formerly BMS-387032), a potent inhibitor of cyclin-dependent kinases 2, 7 and 9 administered as a single oral dose and weekly infusion in patients with metastatic refractory solid tumors.

Published in:

Investigational New Drugs, 2008, v. 26, n. 1, p. 59, doi. 10.1007/s10637-007-9090-3

By:

Elisabeth Heath;
Keith Bible;
Robert Martell;
Daniel Adelman;
Patricia LoRusso

Publication type:

Article

A phase 1 trial of XK469: Toxicity profile of a selective topoisomerase IIβ inhibitor.

Published in:

Investigational New Drugs, 2007, v. 25, n. 2, p. 147, doi. 10.1007/s10637-006-9024-5

By:

Amin Alousi;
Ramesh Boinpally;
Richard Wiegand;
Ralph Parchment;
Shirish Gadgeel;
Lance Heilbrun;
Antionette Wozniak;
Pamela DeLuca;
Patricia LoRusso

Publication type:

Article

A phase I study of flavopiridol and docetaxel.

Published in:

Investigational New Drugs, 2006, v. 24, n. 4, p. 305, doi. 10.1007/s10637-005-4343-5

By:

Basil El-Rayes;
Shirish Gadgeel;
Ralph Parchment;
Patricia Lorusso;
Philip Philip

Publication type:

Article

Phase II trial of fenretinide in advanced renal carcinoma.

Published in:

Investigational New Drugs, 2005, v. 23, n. 2, p. 179, doi. 10.1007/s10637-005-5864-7

By:

Ulka Vaishampayan;
Lance K. Heilbrun;
Ralph E. Parchment;
Vikash Jain;
James Zwiebel;
Ramesh R. Boinpally;
Patricia LoRusso;
Maha Hussain

Publication type:

Article

Phase I study of liposomal doxorubicin (Doxil) and cyclophosphamide in solid tumors.

Published in:

Investigational New Drugs, 2005, v. 23, n. 1, p. 57, doi. 10.1023/B:DRUG.0000047106.20104.a7

By:

Basil F. El-Rayes;
Dina Ibrahim;
Anthony F. Shields;
Patricia M. LoRusso;
Mark M. Zalupski;
Philip A. Philip

Publication type:

Article

Improved methods for RNAseq-based alternative splicing analysis.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-89938-2

By:

Halperin, Rebecca F.;
Hegde, Apurva;
Lang, Jessica D.;
Raupach, Elizabeth A.;
C4RCD Research Group;
Narayanan, Vinodh;
Huentelman, Matt;
Belnap, Newell;
Aziz, Anne-Marie;
Ramsey, Keri;
Legendre, Christophe;
Liang, Winnie S.;
LoRusso, Patricia M.;
Sekulic, Aleksandar;
Sosman, Jeffrey A.;
Trent, Jeffrey M.;
Rangasamy, Sampathkumar;
Pirrotte, Patrick;
Schork, Nicholas J.

Publication type:

Article

Review: Targeting the Hedgehog pathway in cancer.

Published in:

Therapeutic Advances in Medical Oncology, 2010, v. 2, n. 4, p. 237, doi. 10.1177/1758834010366430

By:

Gupta, Sachin;
Takebe, Naoko;
LoRusso, Patricia

Publication type:

Article

A first in man, dose-finding study of the mTORC1/mTORC2 inhibitor OSI-027 in patients with advanced solid malignancies.

Published in:

2016

By:

Mateo, Joaquin;
Olmos, David;
Dumez, Herlinde;
Poondru, Srinivasu;
Samberg, Nancy L;
Barr, Sharon;
Van Tornout, Jan M;
Jie, Fei;
Sandhu, Shahneen;
Tan, Daniel S;
Moreno, Victor;
LoRusso, Patricia M;
Kaye, Stan B;
Schöffski, Patrick;
Schöffski, Patrick

Publication type:

journal article

A phase I dose-escalation study of selumetinib in combination with docetaxel or dacarbazine in patients with advanced solid tumors.

Published in:

2017

By:

LoRusso, Patricia M.;
Infante, Jeffrey R.;
Kim, Kevin B.;
Burris, Howard A.;
Curt, Gregory;
Ugochi Emeribe;
Clemett, Delyth;
Tomkinson, Helen K.;
Cohen, Roger B.;
Burris, Howard A 3rd;
Emeribe, Ugochi

Publication type:

journal article

Pharmacokinetics (PK) of Tiragolumab in First‐in‐Human Study in Patients with Mixed Solid Tumors (GO30103).

Published in:

Journal of Clinical Pharmacology, 2024, v. 64, n. 5, p. 544, doi. 10.1002/jcph.2397

By:

Garralda, Elena;
Oh, Do Youn;
Italiano, Antoine;
Bedard, Philippe L.;
Delord, Jean‐Pierre;
Calvo, Emiliano;
LoRusso, Patricia;
Wainberg, Zev;
Cervantes, Andres;
Rodriguez‐Vida, Alejo;
Shemesh, Colby S.;
Sane, Rucha;
Mendus, Diana;
Ding, Hao;
Hendricks, Robert;
Meng, Ray;
Cho, Byoung Chul;
Kim, Tae Won;
Wu, Benjamin

Publication type:

Article

Pharmacometabolomics Reveals Irinotecan Mechanism of Action in Cancer Patients.

Published in:

Journal of Clinical Pharmacology, 2019, v. 59, n. 1, p. 20, doi. 10.1002/jcph.1275

By:

Bao, Xun;
Wu, Jianmei;
Kim, Seongho;
Li, Jing;
LoRusso, Patricia

Publication type:

Article

Integrating Dynamic Positron Emission Tomography and Conventional Pharmacokinetic Studies to Delineate Plasma and Tumor Pharmacokinetics of FAU, a Prodrug Bioactivated by Thymidylate Synthase.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 11, p. 1433, doi. 10.1002/jcph.751

By:

Li, Jing;
Kim, Seongho;
Shields, Anthony F.;
Douglas, Kirk A.;
McHugh, Christopher I.;
Lawhorn‐Crews, Jawana M.;
Wu, Jianmei;
Mangner, Thomas J.;
LoRusso, Patricia M.

Publication type:

Article

Assessment of the drug interaction potential and single- and repeat-dose pharmacokinetics of the BRAF inhibitor dabrafenib.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 4, p. 392, doi. 10.1002/jcph.437

By:

Suttle, A. Benjamin;
Grossmann, Kenneth F.;
Ouellet, Daniele;
Richards‐Peterson, Lauren E.;
Aktan, Gursel;
Gordon, Michael S.;
LoRusso, Patricia M.;
Infante, Jeffrey R.;
Sharma, Sunil;
Kendra, Kari;
Patel, Manish;
Pant, Shubham;
Arkenau, Hendrik‐Tobias;
Middleton, Mark R.;
Blackman, Samuel C.;
Botbyl, Jeff;
Carson, Stanley W.

Publication type:

Article

Evaluation of the Effects of Food on the Single-Dose Pharmacokinetics of Trametinib, a First-in-Class MEK Inhibitor, in Patients with Cancer.

Published in:

Journal of Clinical Pharmacology, 2013, v. 53, n. 9, p. 946, doi. 10.1002/jcph.115

By:

Cox, Donna S.;
Papadopoulos, Kyri;
Fang, Lei;
Bauman, John;
LoRusso, Patricia;
Tolcher, Anthony;
Patnaik, Amita;
Pendry, Carolyn;
Orford, Keith;
Ouellet, Daniele

Publication type:

Article

Clinical Implications of Pathophysiological and Demographic Covariates on the Population Pharmacokinetics of Trastuzumab Emtansine, a HER2-Targeted Antibody-Drug Conjugate, in Patients With HER2-Positive Metastatic Breast Cancer.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 5, p. 691, doi. 10.1177/0091270011403742

By:

Gupta, Manish;
LoRusso, Patricia M.;
Wang, Bei;
Yi, Joo-Hee;
Burris, Howard A.;
Beeram, Muralidhar;
Modi, Shanu;
Chu, Yu-Waye;
Agresta, Samuel;
Klencke, Barbara;
Joshi, Amita;
Girish, Sandhya

Publication type:

Article

Clinical Pharmacokinetics and Exposure- Toxicity Relationship of a Folate-Vinca Alkaloid Conjugate EC145 in Cancer Patients.

Published in:

Journal of Clinical Pharmacology, 2009, v. 49, n. 12, p. 1467, doi. 10.1177/0091270009339740

By:

Jing Li;
Sausville, Edward A.;
Klein, Patrick J.;
Morgenstern, David;
Leamon, Christopher P.;
Messmann, Richard A.;
LoRusso, Patricia

Publication type:

Article

Pharmacokinetics and Pharmacodynamics of Zoledronic Acid in Cancer Patients with Bone Metastases.

Published in:

Journal of Clinical Pharmacology, 2002, v. 42, n. 11, p. 1228, doi. 10.1177/0091270002238765

By:

Chen, Tianling;
Berenson, James;
Vescio, Robert;
Swift, Regina;
Gilchick, Alicia;
Goodin, Susan;
LoRusso, Patricia;
Ma, Peiming;
Ravera, Christina;
Deckert, Fabienne;
Schran, Horst;
Seaman, John;
Skerjanec, Andrej

Publication type:

Article

Levels of 5-hydroxymethyl-2′-deoxyuridine in DNA from blood as a marker of breast cancer.

Published in:

Cancer (0008543X), 1996, v. 77, n. 4, p. 691, doi. 10.1002/(SICI)1097-0142(19960215)77:4<691::AID-CNCR15>3.0.CO;2-W

By:

Djuric, Zora;
Heilbrun, Lance K.;
Simon, Michael S.;
Smith, Daryn;
Luongo, Domenico A.;
LoRusso, Patricia M.;
Martino, Silvana

Publication type:

Article

Response.

Published in:

2013

By:

Hunsberger, Sally;
Rubinstein, Larry;
Boerner, Scott A;
Lorusso, Patricia

Publication type:

Letter