Works matching AU LoRusso, Patricia

Results: 136

A pharmacodynamically guided dose selection of PF-00337210 in a phase I study in patients with advanced solid tumors.

Published in:

2016

By:

Bruce, Justine;
LoRusso, Patricia;
Goncalves, Priscila;
Heath, Elisabeth;
Sadowski, Elizabeth;
Shalinsky, David;
Zhang, Yanwei;
Traynor, Anne;
Breazna, Aurora;
Ricart, Alejandro;
Tortorici, Michael;
Liu, Glenn;
Bruce, Justine Yang;
LoRusso, Patricia M;
Goncalves, Priscila H;
Heath, Elisabeth I;
Shalinsky, David R;
Traynor, Anne M;
Ricart, Alejandro D

Publication type:

journal article

Bioavailability and pharmacokinetics of the investigational anticancer agent XK469 (NSC 698215) in rats following oral and intravenous administration.

Published in:

2005

By:

Boinpally, Ramesh;
Sen-Lin Zhou;
LoRusso, Patricia;
Parchment, Ralph;
Boinpally, Ramesh R;
Zhou, Sen-Lin;
LoRusso, Patricia M;
Parchment, Ralph E

Publication type:

journal article

Toward Evidence-Based Management of the Dermatologic Effects of EGFR Inhibitors.

Published in:

Oncology (08909091), 2009, v. 23, n. 2, p. 186

By:

Lorusso, Patricia

Publication type:

Article

Quantifying the impact of the COVID-19 pandemic on cancer center clinical trial operations.

Published in:

JNCI Cancer Spectrum, 2023, v. 7, n. 4, p. 1, doi. 10.1093/jncics/pkad048

By:

George, Thomas J;
Lin, Tara L;
Bentz, Tricia Adrales;
Grant, Stefan;
Houston, Collette M;
Nashawati, Melissa A;
Pappu, Bhanu;
Peck, Helen;
Zafirovski, Alex;
Kerstann, Kimberly;
LoRusso, Patricia;
Schnatterly, Anne;
Hofacker, Janie;
Cameron, Kendra;
Honeycutt, Hailey;
Werner, Theresa L

Publication type:

Article

Analysis of Lung Cancer Patients Enrolled in CTEP (Cancer Therapy Evaluation Program)-Sponsored Phase I Trials.

Published in:

Clinical Lung Cancer, 2011, v. 12, n. 4, p. 218, doi. 10.1016/j.cllc.2011.03.022

By:

Gadgeel, Shirish M.;
Ivy, Percy;
Chen, Wei;
Mauer, Joan;
Smith, Daryn;
LoRusso, Patricia

Publication type:

Article

A First-in-Human Phase 1 Study of a Novel Selective Androgen Receptor Modulator (SARM), RAD140, in ER+/HER2- Metastatic Breast Cancer.

Published in:

2022

By:

LoRusso, Patricia;
Hamilton, Erika;
Ma, Cynthia;
Vidula, Neelima;
Bagley, Rebecca G.;
Troy, Steven;
Annett, Miriam;
Ziyang Yu;
Conlan, Maureen G.;
Weise, Amy;
Yu, Ziyang

Publication type:

journal article

Efficacy and Safety of the MDM2–p53 Antagonist Brigimadlin (BI 907828) in Patients with Advanced Biliary Tract Cancer: A Case Series.

Published in:

OncoTargets & Therapy, 2024, v. 17, p. 267, doi. 10.2147/OTT.S440979

By:

Yamamoto, Noboru;
Tolcher, Anthony;
Hafez, Navid;
Lugowska, Iwona;
Ramlau, Rodryg;
Macarulla, Teresa;
Geng, Junxian;
Li, Jian;
Teufel, Michael;
Märten, Angela;
LoRusso, Patricia

Publication type:

Article

Combination of triapine, olaparib, and cediranib suppresses progression of BRCA-wild type and PARP inhibitor-resistant epithelial ovarian cancer.

Published in:

PLoS ONE, 2018, v. 13, n. 11, p. 1, doi. 10.1371/journal.pone.0207399

By:

Lin, Z. Ping;
Zhu, Yong-Lian;
Lo, Ying-Chun;
Moscarelli, Jake;
Xiong, Amy;
Korayem, Yasmin;
Huang, Pamela H.;
Giri, Smith;
LoRusso, Patricia;
Ratner, Elena S.

Publication type:

Article

Pharmacokinetics (PK) of Tiragolumab in First‐in‐Human Study in Patients with Mixed Solid Tumors (GO30103).

Published in:

Journal of Clinical Pharmacology, 2024, v. 64, n. 5, p. 544, doi. 10.1002/jcph.2397

By:

Garralda, Elena;
Oh, Do Youn;
Italiano, Antoine;
Bedard, Philippe L.;
Delord, Jean‐Pierre;
Calvo, Emiliano;
LoRusso, Patricia;
Wainberg, Zev;
Cervantes, Andres;
Rodriguez‐Vida, Alejo;
Shemesh, Colby S.;
Sane, Rucha;
Mendus, Diana;
Ding, Hao;
Hendricks, Robert;
Meng, Ray;
Cho, Byoung Chul;
Kim, Tae Won;
Wu, Benjamin

Publication type:

Article

Pharmacometabolomics Reveals Irinotecan Mechanism of Action in Cancer Patients.

Published in:

Journal of Clinical Pharmacology, 2019, v. 59, n. 1, p. 20, doi. 10.1002/jcph.1275

By:

Bao, Xun;
Wu, Jianmei;
Kim, Seongho;
Li, Jing;
LoRusso, Patricia

Publication type:

Article

Carlumab, an anti-C-C chemokine ligand 2 monoclonal antibody, in combination with four chemotherapy regimens for the treatment of patients with solid tumors: an open-label, multicenter phase 1b study.

Published in:

Targeted Oncology, 2015, v. 10, n. 1, p. 111, doi. 10.1007/s11523-014-0320-2

By:

Brana, Irene;
Calles, Antonio;
LoRusso, Patricia;
Yee, Lorrin;
Puchalski, Thomas;
Seetharam, Shobha;
Zhong, Bob;
Boer, Carla;
Tabernero, Josep;
Calvo, Emiliano

Publication type:

Article

Targeting phosphatidylinositol 3 kinase (PI3K)-Akt beyond rapalogs.

Published in:

2011

By:

Ogita, Shin;
LoRusso, Patricia

Publication type:

journal article

Randomized clinical trial of a brief and extensive dyadic intervention for advanced cancer patients and their family caregivers.

Published in:

Psycho-Oncology, 2013, v. 22, n. 3, p. 555, doi. 10.1002/pon.3036

By:

Northouse, Laurel L.;
Mood, Darlene W.;
Schafenacker, Ann;
Kalemkerian, Gregory;
Zalupski, Mark;
LoRusso, Patricia;
Hayes, Daniel F.;
Hussain, Maha;
Ruckdeschel, John;
Fendrick, A. Mark;
Trask, Peter C.;
Ronis, David L.;
Kershaw, Trace

Publication type:

Article

First-in-human study of oleclumab, a potent, selective anti-CD73 monoclonal antibody, alone or in combination with durvalumab in patients with advanced solid tumors.

Published in:

Cancer Immunology, Immunotherapy, 2023, v. 72, n. 7, p. 2443, doi. 10.1007/s00262-023-03430-6

By:

Bendell, Johanna;
LoRusso, Patricia;
Overman, Michael;
Noonan, Anne M.;
Kim, Dong-Wan;
Strickler, John H.;
Kim, Sang-We;
Clarke, Stephen;
George, Thomas J.;
Grimison, Peter S.;
Barve, Minal;
Amin, Manik;
Desai, Jayesh;
Wise-Draper, Trisha;
Eck, Steven;
Jiang, Yu;
Khan, Anis A.;
Wu, Yuling;
Martin, Philip;
Cooper, Zachary A.

Publication type:

Article

Pharmacokinetic Study of Rucaparib in Patients With Advanced Solid Tumors.

Published in:

Clinical Pharmacology in Drug Development, 2019, v. 8, n. 1, p. 107, doi. 10.1002/cpdd.575

By:

Shapiro, Geoffrey I.;
Kristeleit, Rebecca S.;
Burris, Howard A.;
LoRusso, Patricia;
Patel, Manish R.;
Drew, Yvette;
Giordano, Heidi;
Maloney, Lara;
Watkins, Simon;
Goble, Sandra;
Jaw‐Tsai, Sarah;
Xiao, Jim J.

Publication type:

Article

Protein Expression of DNA Damage Repair Proteins Dictates Response to Topoisomerase and PARP Inhibitors in Triple-Negative Breast Cancer.

Published in:

PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0119614

By:

Boerner, Julie L.;
Nechiporchik, Nicole;
Mueller, Kelly L.;
Polin, Lisa;
Heilbrun, Lance;
Boerner, Scott A.;
Zoratti, Gina L.;
Stark, Karri;
LoRusso, Patricia M.;
Burger, Angelika

Publication type:

Article

Targeted Morphoproteomic Profiling of Ewing's Sarcoma Treated with Insulin-Like Growth Factor 1 Receptor (IGF1R) Inhibitors: Response/Resistance Signatures.

Published in:

PLoS ONE, 2011, v. 6, n. 4, p. 1, doi. 10.1371/journal.pone.0018424

By:

Subbiah, Vivek;
Naing, Aung;
Brown, Robert E.;
Chen, Helen;
Doyle, Laurence;
LoRusso, Patricia;
Benjamin, Robert;
Anderson, Pete;
Kurzrock, Razelle

Publication type:

Article

Clinical responses to selumetinib (AZD6244; ARRY-142886)-based combination therapy stratified by gene mutations in patients with metastatic melanoma.

Published in:

Cancer (0008543X), 2013, v. 119, n. 4, p. 799, doi. 10.1002/cncr.27790

By:

Patel, Sapna P.;
Lazar, Alexander J.;
Papadopoulos, Nicholas E.;
Liu, Ping;
Infante, Jeffrey R.;
Glass, Michelle R.;
Vaughn, Carol S.;
LoRusso, Patricia M.;
Cohen, Roger B.;
Davies, Michael A.;
Kim, Kevin B.

Publication type:

Article

Mammalian Target of Rapamycin as a Rational Therapeutic Target for Breast Cancer Treatment.

Published in:

Oncology, 2012, v. 84, n. 1, p. 43, doi. 10.1159/000343063

By:

LoRusso, Patricia Mucci

Publication type:

Article

Improving Precision Oncology through Better Designs and Reporting of Biomarker-Driven Randomized Clinical Trials.

Published in:

JNCI: Journal of the National Cancer Institute, 2023, v. 115, n. 2, p. 122, doi. 10.1093/jnci/djac212

By:

LoRusso, Patricia M;
Freidlin, Boris

Publication type:

Article

Response.

Published in:

2013

By:

Hunsberger, Sally;
Rubinstein, Larry;
Boerner, Scott A;
Lorusso, Patricia

Publication type:

Letter

RE: Meta-analysis of the Relationship Between Dose and Benefit in Phase I Targeted Agent Trials.

Published in:

2013

By:

JOFFE, STEVEN;
HUNSBERGER, SALLY;
RUBINSTEIN, LARRY;
BOERNER, SCOTT A.;
LORUSSO, PATRICIA

Publication type:

Letter

Meta-analysis of the Relationship Between Dose and Benefit in Phase I Targeted Agent Trials.

Published in:

JNCI: Journal of the National Cancer Institute, 2012, v. 104, n. 24, p. 1860, doi. 10.1093/jnci/djs439

By:

Gupta, Sachin;
Hunsberger, Sally;
Boerner, Scott A.;
Rubinstein, Larry;
Royds, Robert;
Ivy, Percy;
LoRusso, Patricia

Publication type:

Article

The Role of Phosphoinositide 3-Kinase in Breast Cancer: An Overview.

Published in:

Clinical Breast Cancer, 2010, v. 10, p. S56, doi. 10.3816/CBC.2010.s.012

By:

LoRusso, Patricia M.;
Boerner, Scott A.

Publication type:

Article

First-in-human phase 1 dose-escalation results with livmoniplimab, an antibody targeting the GARP:TGF-ß1 complex, as monotherapy and in combination with the anti–PD-1 antibody budigalimab in patients with advanced solid tumors.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2024.1376551

By:

Shimizu, Toshio;
Powderly, John;
Abdul Razak, Albiruni;
LoRusso, Patricia;
Miller, Kathy D.;
Kao, Steven;
Kongpachith, Sarah;
Tribouley, Catherine;
Graham, Michelle;
Stoll, Brian;
Patel, Maulik;
Sahtout, Mohammad;
Blaney, Martha;
Leibman, Rachel;
Golan, Talia;
Tolcher, Anthony

Publication type:

Article

Corrigendum: First-in-human phase 1 dose-escalation results with livmoniplimab, an antibody targeting the GARP: TGF-ß1 complex, as monotherapy and in combination with the anti–PD-1 antibody budigalimab in patients with advanced solid tumors.

Published in:

2025

By:

Shimizu, Toshio;
Powderly, John;
Abdul Razak, Albiruni;
LoRusso, Patricia;
Miller, Kathy D.;
Kao, Steven;
Kongpachith, Sarah;
Tribouley, Catherine;
Graham, Michelle;
Stoll, Brian;
Patel, Maulik;
Sahtout, Mohammad;
Blaney, Martha;
Leibman, Rachel;
Golan, Talia;
Tolcher, Anthony

Publication type:

Correction Notice

First-in-human phase 1 dose-escalation results with livmoniplimab, an antibody targeting the GARP:TGF-ß1 complex, as monotherapy and in combination with the anti–PD-1 antibody budigalimab in patients with advanced solid tumors.

Published in:

Frontiers in Oncology, 2024, p. 1, doi. 10.3389/fonc.2024.1376551

By:

Shimizu, Toshio;
Powderly, John;
Abdul Razak, Albiruni;
LoRusso, Patricia;
Miller, Kathy D.;
Kao, Steven;
Kongpachith, Sarah;
Tribouley, Catherine;
Graham, Michelle;
Stoll, Brian;
Patel, Maulik;
Sahtout, Mohammad;
Blaney, Martha;
Leibman, Rachel;
Golan, Talia;
Tolcher, Anthony

Publication type:

Article

Genome-wide analysis of aberrant position and sequence of plasma DNA fragment ends in patients with cancer.

Published in:

Science Translational Medicine, 2023, v. 15, n. 678, p. 1, doi. 10.1126/scitranslmed.abm6863

By:

Budhraja, Karan K.;
McDonald, Bradon R.;
Stephens, Michelle D.;
Contente-Cuomo, Tania;
Markus, Havell;
Farooq, Maria;
Favaro, Patricia F.;
Connor, Sydney;
Byron, Sara A.;
Egan, Jan B.;
Ernst, Brenda;
McDaniel, Timothy K.;
Sekulic, Aleksandar;
Tran, Nhan L.;
Prados, Michael D.;
Borad, Mitesh J.;
Berens, Michael E.;
Pockaj, Barbara A.;
LoRusso, Patricia M.;
Bryce, Alan

Publication type:

Article

Review: Targeting the Hedgehog pathway in cancer.

Published in:

Therapeutic Advances in Medical Oncology, 2010, v. 2, n. 4, p. 237, doi. 10.1177/1758834010366430

By:

Gupta, Sachin;
Takebe, Naoko;
LoRusso, Patricia

Publication type:

Article

A phase II study of bortezomib in the treatment of metastatic malignant melanoma.

Published in:

Cancer (0008543X), 2005, v. 103, n. 12, p. 2584

By:

Svetomir N. Markovic;
Susan M. Geyer;
Fitzroy Dawkins;
William Sharfman;
Mark Albertini;
William Maples;
Paula M. Fracasso;
Tom Fitch;
Patricia LoRusso;
Alex A. Adjei;
Charles Erlichman

Publication type:

Article

Preclinical and first-in-human phase I studies of KW-2450, an oral tyrosine kinase inhibitor with insulin-like growth factor receptor-1/insulin receptor selectivity.

Published in:

Cancer Science, 2016, v. 107, n. 4, p. 499, doi. 10.1111/cas.12906

By:

Schwartz, Gary K.;
Dickson, Mark A.;
LoRusso, Patricia M.;
Sausville, Edward A.;
Maekawa, Yoshimi;
Watanabe, Yasuo;
Kashima, Naomi;
Nakashima, Daisuke;
Akinaga, Shiro

Publication type:

Article

Assessment of effects of repeated oral doses of fedratinib on inhibition of cytochrome P450 activities in patients with solid tumors using a cocktail approach.

Published in:

Cancer Chemotherapy & Pharmacology, 2020, v. 86, n. 1, p. 87, doi. 10.1007/s00280-020-04102-3

By:

Ogasawara, Ken;
LoRusso, Patricia M.;
Olszanski, Anthony J.;
Rixe, Olivier;
Xu, Christine;
Yin, Jian;
Palmisano, Maria;
Krishna, Gopal

Publication type:

Article

Pharmacokinetics and safety of vismodegib in patients with advanced solid malignancies and hepatic impairment.

Published in:

2017

By:

Abou-Alfa, Ghassan;
Lewis, Lionel;
LoRusso, Patricia;
Maitland, Michael;
Chandra, Priya;
Cheeti, Sravanthi;
Colburn, Dawn;
Williams, Sarah;
Simmons, Brian;
Graham, Richard;
Abou-Alfa, Ghassan K;
Lewis, Lionel D;
Graham, Richard A

Publication type:

journal article

Lack of pharmacokinetic drug-drug interaction between ramucirumab and irinotecan in patients with advanced solid tumors.

Published in:

2016

By:

Wang, Ding;
Braiteh, Fadi;
Lee, James;
Denlinger, Crystal;
Shepard, Dale;
Chaudhary, Archana;
Lin, Yong;
Gao, Ling;
Asakiewicz, Christopher;
Nasroulah, Federico;
LoRusso, Patricia;
Lee, James J;
Denlinger, Crystal S;
Shepard, Dale R

Publication type:

journal article

Evaluation of the effect of necitumumab on the corrected QT interval in patients with advanced solid tumors.

Published in:

2016

By:

Smith, David;
Powderly, John;
Lee, James;
Shepard, Dale;
Wallin, Johan;
Chaudhary, Archana;
Chao, Grace;
Ng, Wee;
Mitchell, Malcolm;
Grau, Gerrit;
Kurek, Raffael;
LoRusso, Patricia;
Smith, David C;
Lee, James J;
Shepard, Dale R;
Chao, Grace Yi;
Ng, Wee Teck;
Mitchell, Malcolm I

Publication type:

journal article

ASP9853, an inhibitor of inducible nitric oxide synthase dimerization, in combination with docetaxel: preclinical investigation and a Phase I study in advanced solid tumors.

Published in:

2016

By:

Luke, Jason;
LoRusso, Patricia;
Shapiro, Geoffrey;
Krivoshik, Andrew;
Schuster, Robin;
Yamazaki, Takao;
Arai, Yukinori;
Fakhoury, Allam;
Dmuchowski, Carl;
Infante, Jeffrey;
Luke, Jason J;
Shapiro, Geoffrey I;
Infante, Jeffrey R

Publication type:

journal article

Safety, efficacy, and pharmacokinetics of navitoclax (ABT-263) in combination with irinotecan: results of an open-label, phase 1 study.

Published in:

2015

By:

Tolcher, Anthony;
LoRusso, Patricia;
Arzt, Jennifer;
Busman, Todd;
Lian, Guinan;
Rudersdorf, Niki;
Vanderwal, Carol;
Waring, Jeffrey;
Yang, Jianning;
Holen, Kyle;
Rosen, Lee;
Tolcher, Anthony W;
Busman, Todd A;
Rudersdorf, Niki S;
Vanderwal, Carol Ann;
Waring, Jeffrey F;
Holen, Kyle D;
Rosen, Lee S

Publication type:

journal article

Safety, efficacy, and pharmacokinetics of navitoclax (ABT-263) in combination with erlotinib in patients with advanced solid tumors.

Published in:

2015

By:

Tolcher, Anthony;
LoRusso, Patricia;
Arzt, Jennifer;
Busman, Todd;
Lian, Guinan;
Rudersdorf, Niki;
Vanderwal, Carol;
Kirschbrown, Whitney;
Holen, Kyle;
Rosen, Lee;
Tolcher, Anthony W;
Busman, Todd A;
Rudersdorf, Niki S;
Vanderwal, Carol Ann;
Holen, Kyle D;
Rosen, Lee S

Publication type:

journal article

Results of a phase 1, randomized study evaluating the effects of food and diurnal variation on the pharmacokinetics of linifanib.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 1, p. 55, doi. 10.1007/s00280-014-2475-z

By:

Xiong, Hao;
Chiu, Yi-Lin;
Ricker, Justin;
LoRusso, Patricia

Publication type:

Article

A phase I study of oral ixabepilone in patients with advanced solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 73, n. 5, p. 1071, doi. 10.1007/s00280-014-2443-7

By:

Deeken, John;
Marshall, John;
Pishvaian, Michael;
Hwang, Jimmy;
Ahlers, Christoph;
Clemens, Pamela;
Parker, Susan;
Iacono, Lisa;
LoRusso, Patricia

Publication type:

Article

A Phase Ib study evaluating MNRP1685A, a fully human anti-NRP1 monoclonal antibody, in combination with bevacizumab and paclitaxel in patients with advanced solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 73, n. 5, p. 951, doi. 10.1007/s00280-014-2426-8

By:

Patnaik, Amita;
LoRusso, Patricia;
Messersmith, Wells;
Papadopoulos, Kyriakos;
Gore, Lia;
Beeram, Muralidhar;
Ramakrishnan, Vanitha;
Kim, Amy;
Beyer, Joseph;
Mason Shih, L.;
Darbonne, Walter;
Xin, Yan;
Yu, Ron;
Xiang, Hong;
Brachmann, Rainer;
Weekes, Colin

Publication type:

Article

Phase I dose-escalation study of AZD7762, a checkpoint kinase inhibitor, in combination with gemcitabine in US patients with advanced solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 73, n. 3, p. 539, doi. 10.1007/s00280-014-2380-5

By:

Sausville, Edward;
LoRusso, Patricia;
Carducci, Michael;
Carter, Judith;
Quinn, Mary;
Malburg, Lisa;
Azad, Nilofer;
Cosgrove, David;
Knight, Richard;
Barker, Peter;
Zabludoff, Sonya;
Agbo, Felix;
Oakes, Patricia;
Senderowicz, Adrian

Publication type:

Article

Results of a phase I, open-label, randomized, crossover study evaluating the effects of linifanib on QTc intervals in patients with solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 73, n. 1, p. 213, doi. 10.1007/s00280-013-2351-2

By:

Chiu, Yi-Lin;
LoRusso, Patricia;
Hosmane, Balakrishna;
Ricker, Justin;
Awni, Walid;
Carlson, Dawn

Publication type:

Article

Phase I study evaluating the combination of lapatinib (a Her2/Neu and EGFR inhibitor) and everolimus (an mTOR inhibitor) in patients with advanced cancers: South West Oncology Group (SWOG) Study S0528.

Published in:

Cancer Chemotherapy & Pharmacology, 2013, v. 72, n. 5, p. 1089, doi. 10.1007/s00280-013-2297-4

By:

Gadgeel, Shirish;
Lew, Danika;
Synold, Timothy;
LoRusso, Patricia;
Chung, Vincent;
Christensen, Scott;
Smith, David;
Kingsbury, Laura;
Hoering, Antje;
Kurzrock, Razelle

Publication type:

Article

A randomized, double-blind, placebo-controlled study to evaluate the effect of repeated oral doses of pazopanib on cardiac conduction in patients with solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2013, v. 71, n. 3, p. 565, doi. 10.1007/s00280-012-2030-8

By:

Heath, Elisabeth;
Infante, Jeffrey;
Lewis, Lionel;
Luu, Thehang;
Stephenson, Joe;
Tan, Antoinette;
Kasubhai, Saifuddin;
LoRusso, Patricia;
Ma, Bo;
Suttle, A.;
Kleha, Joseph;
Ball, Howard;
Dar, Mohammed

Publication type:

Article

Co-administration of vismodegib with rosiglitazone or combined oral contraceptive in patients with locally advanced or metastatic solid tumors: a pharmacokinetic assessment of drug-drug interaction potential.

Published in:

Cancer Chemotherapy & Pharmacology, 2013, v. 71, n. 1, p. 193, doi. 10.1007/s00280-012-1996-6

By:

LoRusso, Patricia;
Piha-Paul, Sarina;
Mita, Monica;
Colevas, A.;
Malhi, Vikram;
Colburn, Dawn;
Yin, Ming;
Low, Jennifer;
Graham, Richard

Publication type:

Article

A phase I study of tasisulam sodium (LY573636 sodium), a novel anticancer compound, administered as a 24-h continuous infusion in patients with advanced solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2013, v. 71, n. 1, p. 21, doi. 10.1007/s00280-012-1917-8

By:

Gordon, Michael;
Ilaria, Robert;
Alwis, Dinesh;
Mendelson, David;
McKane, Scott;
Wagner, Margaret;
Look, Katherine;
LoRusso, Patricia

Publication type:

Article

Clinical pharmacology of trastuzumab emtansine (T-DM1): an antibody-drug conjugate in development for the treatment of HER2-positive cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 5, p. 1229, doi. 10.1007/s00280-011-1817-3

By:

Girish, Sandhya;
Gupta, Manish;
Wang, Bei;
Lu, Dan;
Krop, Ian;
Vogel, Charles;
Burris III, Howard;
LoRusso, Patricia;
Yi, Joo-Hee;
Saad, Ola;
Tong, Barbara;
Chu, Yu-Waye;
Holden, Scott;
Joshi, Amita

Publication type:

Article

Lack of food effect on single-dose pharmacokinetics of brivanib, and safety and efficacy following multiple doses in subjects with advanced or metastatic solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1377, doi. 10.1007/s00280-011-1603-2

By:

LoRusso, Patricia;
Shapiro, Geoffrey;
Hurwitz, Herbert;
Pilat, Mary;
Chemidlin, Janice;
Kollia, Georgia;
Syed, Shariq;
Fischer, Bruce;
Masson, Eric

Publication type:

Article

Dose-escalating and pharmacological study of bortezomib in adult cancer patients with impaired renal function: a National Cancer Institute Organ Dysfunction Working Group Study.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1439, doi. 10.1007/s00280-011-1637-5

By:

Leal, Ticiana;
Remick, Scot;
Takimoto, Chris;
Ramanathan, Ramesh;
Davies, Angela;
Egorin, Merrill;
Hamilton, Anne;
LoRusso, Patricia;
Shibata, Stephen;
Lenz, Heinz-Josef;
Mier, James;
Sarantopoulos, John;
Mani, Sridhar;
Wright, John;
Ivy, S.;
Neuwirth, Rachel;
Moltke, Lisa;
Venkatakrishnan, Karthik;
Mulkerin, Daniel

Publication type:

Article