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Interleukin-1 Receptor-Associated Kinase 1 in Cancer Metastasis and Therapeutic Resistance: Mechanistic Insights and Translational Advances.
Published in:
Cells (2073-4409), 2024, v. 13, n. 20, p. 1690, doi. 10.3390/cells13201690
By:
- Najjar, Mariana K.;
- Khan, Munazza S.;
- Zhuang, Chuling;
- Chandra, Ankush;
- Lo, Hui-Wen
Publication type:
Article
Bazedoxifene as a Potential Cancer Therapeutic Agent Targeting IL-6/GP130 Signaling.
Published in:
Current Oncology, 2024, v. 31, n. 10, p. 5737, doi. 10.3390/curroncol31100426
By:
- Shi, Changyou;
- Bopp, Taylor;
- Lo, Hui-Wen;
- Tkaczuk, Katherine;
- Lin, Jiayuh
Publication type:
Article
Characterization and Proteomic Analysis of Endometrial Stromal Cell–Derived Small Extracellular Vesicles.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2021, v. 106, n. 5, p. 1516, doi. 10.1210/clinem/dgab045
By:
- Hsu, Chia-Yi;
- Hsieh, Tsung-Hua;
- Lin, Hsiao-Yun;
- Lu, Chi-Yu;
- Lo, Hui-Wen;
- Tsai, Ching-Chou;
- Tsai, Eing-Mei
Publication type:
Article
LLY17, a novel small molecule STAT3 inhibitor induces apoptosis and suppresses cell migration and tumor growth in triple-negative breast cancer.
Published in:
Breast Cancer Research & Treatment, 2020, v. 181, n. 1, p. 31, doi. 10.1007/s10549-020-05613-6
By:
- Pan, Li;
- Chen, Xiang;
- Fu, Shengling;
- Yu, Wenying;
- Li, Chenglong;
- Wang, Tiffany;
- Lo, Hui-Wen;
- Lin, Jiayuh
Publication type:
Article
Bazedoxifene is a novel IL-6/GP130 inhibitor for treating triple-negative breast cancer.
Published in:
Breast Cancer Research & Treatment, 2019, v. 175, n. 3, p. 553, doi. 10.1007/s10549-019-05183-2
By:
- Tian, Jilai;
- Chen, Xiang;
- Fu, Shengling;
- Zhang, Ruijie;
- Pan, Li;
- Cao, Yang;
- Wu, Xiaojuan;
- Xiao, Hui;
- Lin, Huey-Jen;
- Lo, Hui-Wen;
- Zhang, Ying;
- Lin, Jiayuh
Publication type:
Article
Glioblastoma radiomics: can genomic and molecular characteristics correlate with imaging response patterns?
Published in:
Neuroradiology, 2018, v. 60, n. 10, p. 1043, doi. 10.1007/s00234-018-2060-y
By:
- Soike, Michael H.;
- McTyre, Emory R.;
- Shah, Nameeta;
- Puchalski, Ralph B.;
- Holmes, Jordan A.;
- Paulsson, Anna K.;
- Miller, Lance D.;
- Cramer, Christina K.;
- Lesser, Glenn J.;
- Strowd, Roy E.;
- Hinson, William H.;
- Mott, Ryan T.;
- Johnson, Annette J.;
- Lo, Hui-Wen;
- Laxton, Adrian W.;
- Tatter, Stephen B.;
- Debinski, Waldemar;
- Chan, Michael D.
Publication type:
Article
Five-year survivors from brain metastases treated with stereotactic radiosurgery: Biology, improving treatments, or just plain luck?
Published in:
Neuro-Oncology Practice, 2023, v. 10, n. 2, p. 195, doi. 10.1093/nop/npac095
By:
- Pearce, Jane B;
- Hsu, Fang-Chi;
- Lanier, Claire M;
- Cramer, Christina K;
- Ruiz, Jimmy;
- Lo, Hui-Wen;
- Xing, Fei;
- Smith, Margaret;
- Li, Wencheng;
- Whitlow, Christopher;
- White, Jaclyn J;
- Tatter, Stephen B;
- Laxton, Adrian W;
- Chan, Michael D
Publication type:
Article
Clinical outcomes of dose-escalated re-irradiation in patients with recurrent high-grade glioma.
Published in:
Neuro-Oncology Practice, 2022, v. 9, n. 5, p. 390, doi. 10.1093/nop/npac032
By:
- Helis, Corbin A;
- Prim, Shih-Ni;
- Cramer, Christina K;
- Strowd, Roy;
- Lesser, Glenn J;
- White, Jaclyn J;
- Tatter, Stephen B;
- Laxton, Adrian W;
- Whitlow, Christopher;
- Lo, Hui-Wen;
- Debinski, Waldemar;
- Ververs, James D;
- Black, Paul J;
- Chan, Michael D
Publication type:
Article
HER2 Phosphorylates and Destabilizes Pro-Apoptotic PUMA, Leading to Antagonized Apoptosis in Cancer Cells.
Published in:
PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0078836
By:
- Carpenter, Richard L.;
- Han, Woody;
- Paw, Ivy;
- Lo, Hui-Wen
Publication type:
Article
Cyclic AMP mediated GSTP1 gene activation in tumor cells involves the interaction of activated CREB-1 with the GSTP1 CRE: A novel mechanism of cellular GSTP1 gene regulation.
Published in:
Journal of Cellular Biochemistry, 2002, v. 87, n. 1, p. 103, doi. 10.1002/jcb.10275
By:
- Lo, Hui-Wen;
- Ali-Osman, Francis
Publication type:
Article
TGFBR1*6A as a modifier of breast cancer risk and progression: advances and future prospects.
Published in:
NPJ Breast Cancer, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41523-022-00446-6
By:
- Agyemang, Kojo;
- Johansen, Allan M.;
- Barker, Grayson W.;
- Pennison, Michael J.;
- Sheffield, Kimberly;
- Jimenez, Hugo;
- Blackman, Carl;
- Sharma, Sambad;
- Fordjour, Patrick A.;
- Singh, Ravi;
- Cook, Katherine L.;
- Lin, Hui-Kuan;
- Zhang, Wei;
- Lo, Hui-Wen;
- Watabe, Kounosuke;
- Sun, Peiqing;
- Langefeld, Carl D.;
- Pasche, Boris
Publication type:
Article
Correction: Regua et al. TrkA Interacts with and Phosphorylates STAT3 to Enhance Gene Transcription and Promote Breast Cancer Stem Cells in Triple-Negative and HER2-Enriched Breast Cancers. Cancers 2021, 13 , 2340.
Published in:
2024
By:
- Regua, Angelina T.;
- Aguayo, Noah R.;
- Jalboush, Sara Abu;
- Doheny, Daniel L.;
- Manore, Sara G.;
- Zhu, Dongqin;
- Wong, Grace L.;
- Arrigo, Austin;
- Wagner, Calvin J.;
- Yu, Yang;
- Thomas, Alexandra;
- Chan, Michael D.;
- Ruiz, Jimmy;
- Jin, Guangxu;
- Strowd, Roy;
- Sun, Peiqing;
- Lin, Jiayuh;
- Lo, Hui-Wen
Publication type:
Correction Notice
Tumor Suppressor Candidate 2 (TUSC2): Discovery, Functions, and Cancer Therapy.
Published in:
Cancers, 2023, v. 15, n. 9, p. 2455, doi. 10.3390/cancers15092455
By:
- Arrigo, Austin;
- Regua, Angelina T.;
- Najjar, Mariana K.;
- Lo, Hui-Wen
Publication type:
Article
An FDA-Approved Antifungal, Ketoconazole, and Its Novel Derivative Suppress tGLI1-Mediated Breast Cancer Brain Metastasis by Inhibiting the DNA-Binding Activity of Brain Metastasis-Promoting Transcription Factor tGLI1.
Published in:
Cancers, 2022, v. 14, n. 17, p. 4256, doi. 10.3390/cancers14174256
By:
- Doheny, Daniel;
- Manore, Sara;
- Sirkisoon, Sherona R.;
- Zhu, Dongqin;
- Aguayo, Noah R.;
- Harrison, Alexandria;
- Najjar, Mariana;
- Anguelov, Marlyn;
- Cox, Anderson O'Brien;
- Furdui, Cristina M.;
- Watabe, Kounosuke;
- Hollis, Thomas;
- Thomas, Alexandra;
- Strowd, Roy;
- Lo, Hui-Wen
Publication type:
Article
TrkA Interacts with and Phosphorylates STAT3 to Enhance Gene Transcription and Promote Breast Cancer Stem Cells in Triple-Negative and HER2-Enriched Breast Cancers.
Published in:
Cancers, 2021, v. 13, n. 10, p. 2340, doi. 10.3390/cancers13102340
By:
- Regua, Angelina T.;
- Aguayo, Noah R.;
- Jalboush, Sara Abu;
- Doheny, Daniel L.;
- Manore, Sara G.;
- Zhu, Dongqin;
- Wong, Grace L.;
- Arrigo, Austin;
- Wagner, Calvin J.;
- Yu, Yang;
- Thomas, Alexandra;
- Chan, Michael D.;
- Ruiz, Jimmy;
- Jin, Guangxu;
- Strowd, Roy;
- Sun, Peiqing;
- Lin, Jiayuh;
- Lo, Hui-Wen
Publication type:
Article
Exosomal MicroRNAs and Organotropism in Breast Cancer Metastasis.
Published in:
Cancers, 2020, v. 12, n. 7, p. 1827, doi. 10.3390/cancers12071827
By:
- Wong, Grace L.;
- Abu Jalboush, Sara;
- Lo, Hui-Wen
Publication type:
Article
Inhibiting TRK Proteins in Clinical Cancer Therapy.
Published in:
Cancers, 2018, v. 10, n. 4, p. 105, doi. 10.3390/cancers10040105
By:
- Lange, Allison M.;
- Lo, Hui-Wen
Publication type:
Article
CD138 plasma cells may predict brain metastasis recurrence following resection and stereotactic radiosurgery.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-50298-7
By:
- Soike, Michael H.;
- Logue, Jennifer;
- Qasem, Shadi;
- Hughes, Ryan T.;
- McTyre, Emory;
- Su, Jing;
- Triozzi, Pierre;
- Bendandi, Maurizio;
- Lo, Hui-Wen;
- Ahmed, Tamjeed;
- O'Neill, Stacey S.;
- Debinski, Waldemar;
- Pasche, Boris;
- Watabe, Kounosuke;
- Miller, Lance D.;
- Chan, Michael D.;
- Ruiz, Jimmy
Publication type:
Article
Multi-Omics Analysis of Brain Metastasis Outcomes Following Craniotomy.
Published in:
Frontiers in Oncology, 2021, v. 11, p. N.PAG, doi. 10.3389/fonc.2020.615472
By:
- Su, Jing;
- Song, Qianqian;
- Qasem, Shadi;
- O'Neill, Stacey;
- Lee, Jingyun;
- Furdui, Cristina M.;
- Pasche, Boris;
- Metheny-Barlow, Linda;
- Masters, Adrianna H.;
- Lo, Hui-Wen;
- Xing, Fei;
- Watabe, Kounosuke;
- Miller, Lance D.;
- Tatter, Stephen B.;
- Laxton, Adrian W.;
- Whitlow, Christopher T.;
- Chan, Michael D.;
- Soike, Michael H.;
- Ruiz, Jimmy
Publication type:
Article
hDirect-MAP: projection-free single-cell modeling of response to checkpoint immunotherapy.
Published in:
Briefings in Bioinformatics, 2022, v. 23, n. 2, p. 1, doi. 10.1093/bib/bbab575
By:
- Lu, Yong;
- Xue, Gang;
- Zheng, Ningbo;
- Han, Kun;
- Yang, Wenzhong;
- Wang, Rui-Sheng;
- Wu, Lingyun;
- Miller, Lance D;
- Pardee, Timothy;
- Triozzi, Pierre L;
- Lo, Hui-Wen;
- Watabe, Kounosuke;
- Wong, Stephen T C;
- Pasche, Boris C;
- Zhang, Wei;
- Jin, Guangxu
Publication type:
Article
STAT1 gene expression is enhanced by nuclear EGFR and HER2 via cooperation With STAT3.
Published in:
Molecular Carcinogenesis, 2013, v. 52, n. 12, p. 959, doi. 10.1002/mc.21936
By:
- Han, Woody;
- Carpenter, Richard L.;
- Cao, Xinyu;
- Lo, Hui‐Wen
Publication type:
Article
Identification of CD37, cystatin A, and IL-23A gene expression in association with brain metastasis: analysis of a prospective trial.
Published in:
International Journal of Biological Markers, 2019, v. 34, n. 1, p. 90, doi. 10.1177/1724600818803104
By:
- Dohm, Ammoren;
- Su, Jing;
- McTyre, Emory R.;
- Taylor, James M.;
- Miller, Lance D.;
- Petty, W. Jeffrey;
- Xing, Fei;
- Lo, Hui-Wen;
- Metheny-Barlow, Linda J.;
- O'Neill, Stacey;
- Bellinger, Christina;
- Dotson, Travis;
- Pasche, Boris;
- Watabe, Kounosuke;
- Chan, Michael D.;
- Ruiz, Jimmy
Publication type:
Article
Hedgehog Signaling and Truncated GLI1 in Cancer.
Published in:
Cells (2073-4409), 2020, v. 9, n. 9, p. 2114, doi. 10.3390/cells9092114
By:
- Doheny, Daniel;
- Manore, Sara G.;
- Wong, Grace L.;
- Lo, Hui-Wen
Publication type:
Article
Long term survivors of stereotactic radiosurgery for brain metastases: do distant brain failures reach a plateau and what factors are associated with a brain metastasis velocity of zero?
Published in:
Journal of Neuro-Oncology, 2022, v. 160, n. 3, p. 643, doi. 10.1007/s11060-022-04183-5
By:
- Lanier, Claire M.;
- Pearce, Jane;
- Isom, Scott;
- Xing, Fei;
- Lo, Hui-Wen;
- Whitlow, Christopher T.;
- Ruiz, Jimmy;
- White, Jaclyn J.;
- Laxton, Adrian W.;
- Tatter, Stephen B.;
- Cramer, Christina K.;
- Chan, Michael D.
Publication type:
Article
Local control outcomes for combination of stereotactic radiosurgery and immunotherapy for non-small cell lung cancer brain metastases.
Published in:
Journal of Neuro-Oncology, 2022, v. 157, n. 1, p. 101, doi. 10.1007/s11060-022-03951-7
By:
- Abdulhaleem, Mohammed;
- Johnston, Hannah;
- D'Agostino Jr., Ralph;
- Lanier, Claire;
- LeCompte, Michael;
- Cramer, Christina K.;
- Ruiz, Jimmy;
- Lycan, Thomas;
- Lo, Hui-Wen;
- Watabe, Kuonosuke;
- O'Neill, Stacey;
- Whitlow, Christopher;
- White, Jaclyn J.;
- Tatter, Stephen B.;
- Laxton, Adrian W.;
- Su, Jing;
- Chan, Michael D.
Publication type:
Article
Single-cell sequencing reveals the landscape of the human brain metastatic microenvironment.
Published in:
Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-05124-2
By:
- Song, Qianqian;
- Ruiz, Jimmy;
- Xing, Fei;
- Lo, Hui-Wen;
- Craddock, Lou;
- Pullikuth, Ashok K.;
- Miller, Lance D.;
- Soike, Michael H.;
- O'Neill, Stacey S.;
- Watabe, Kounosuke;
- Chan, Michael D.;
- Su, Jing
Publication type:
Article
IL-6/JAK/STAT3 Signaling in Breast Cancer Metastasis: Biology and Treatment.
Published in:
Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.866014
By:
- Manore, Sara G.;
- Doheny, Daniel L.;
- Wong, Grace L.;
- Lo, Hui-Wen
Publication type:
Article

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