Works by Lo, Donald C.

Results: 33

Cover Feature: High‐Throughput Platform for Novel Reaction Discovery (Chem. Eur. J. 50/2022).

Published in:

2022

By:

Lu, Xiao;
Luo, Zhiji;
Huang, Ruili;
Lo, Donald C.;
Huang, Wenwei

Publication type:

Abstract

High‐Throughput Platform for Novel Reaction Discovery.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 50, p. 1, doi. 10.1002/chem.202201421

By:

Lu, Xiao;
Luo, Zhiji;
Huang, Ruili;
Lo, Donald C.;
Huang, Wenwei

Publication type:

Article

Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.592737

By:

Chen, Catherine Z.;
Shinn, Paul;
Itkin, Zina;
Eastman, Richard T.;
Bostwick, Robert;
Rasmussen, Lynn;
Huang, Ruili;
Shen, Min;
Hu, Xin;
Wilson, Kelli M.;
Brooks, Brianna M.;
Guo, Hui;
Zhao, Tongan;
Klump-Thomas, Carleen;
Simeonov, Anton;
Michael, Samuel G.;
Lo, Donald C.;
Hall, Matthew D.;
Zheng, Wei

Publication type:

Article

Preclinical target validation for non-addictive therapeutics development for pain.

Published in:

Expert Opinion on Therapeutic Targets, 2022, v. 26, n. 9, p. 811, doi. 10.1080/14728222.2022.2147063

By:

Hargreaves, Richard;
Akinsanya, Karen;
Ajit, Seena K.;
Dhruv, Neel T.;
Driscoll, Jamie;
Farina, Peter;
Gavva, Narender;
Gill, Marie;
Houghton, Andrea;
Iyengar, Smriti;
Jones, Carrie;
Kavelaars, Annemieke;
Kaykas, Ajamete;
Koroshetz, Walter J.;
Laeng, Pascal;
Laird, Jennifer M.;
Lo, Donald C.;
Luthman, Johan;
Munro, Gordon;
Oshinsky, Michael L.

Publication type:

Article

Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models.

Published in:

Nature Medicine, 2013, v. 19, n. 8, p. 1030, doi. 10.1038/nm.3246

By:

Marco, Sonia;
Giralt, Albert;
Petrovic, Milos M;
Pouladi, Mahmoud A;
Martínez-Turrillas, Rebeca;
Martínez-Hernández, José;
Kaltenbach, Linda S;
Torres-Peraza, Jesús;
Graham, Rona K;
Watanabe, Masahiko;
Luján, Rafael;
Nakanishi, Nobuki;
Lipton, Stuart A;
Lo, Donald C;
Hayden, Michael R;
Alberch, Jordi;
Wesseling, John F;
Pérez-Otaño, Isabel

Publication type:

Article

Challenges for neuroscience in a post-genome world.

Published in:

Nature Neuroscience, 2001, v. 4, n. 11, p. 1153, doi. 10.1038/nn1101-1153

By:

Lo, Donald C.

Publication type:

Article

CNTF II, I presume?

Published in:

Nature Neuroscience, 2000, v. 3, n. 9, p. 851, doi. 10.1038/78738

By:

Lesser, Steven S.;
Lo, Donald C.

Publication type:

Article

Truncated and full-length TrkB receptors regulate distinct modes of dendritic growth.

Published in:

Nature Neuroscience, 2000, v. 3, n. 4, p. 342, doi. 10.1038/73911

By:

Yacoubian, Talene A.;
Lo, Donald C.

Publication type:

Article

Perturbation with Intrabodies Reveals That Calpain Cleavage Is Required for Degradation of Huntingtin Exon 1.

Published in:

PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0016676

By:

Southwell, Amber L.;
Bugg, Charles W.;
Kaltenbach, Linda S.;
Dunn, Denise;
Butland, Stefanie;
Weiss, Andreas;
Paganetti, Paolo;
Lo, Donald C.;
Patterson, Paul H.

Publication type:

Article

Neuroprotective Effects of Annexin A1 Tripeptide after Deep Hypothermic Circulatory Arrest in Rats.

Published in:

Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01050

By:

Zhiquan Zhang;
Qing Ma;
Shah, Bijal;
Mackensen, G. Burkhard;
Lo, Donald C.;
Mathew, Joseph P.;
Podgoreanu, Mihai V.;
Terrando, Niccolò

Publication type:

Article

IKKβ and mutant huntingtin interactions regulate the expression of IL-34: implications for microglialmediated neurodegeneration in HD.

Published in:

Human Molecular Genetics, 2017, v. 26, n. 21, p. 4267, doi. 10.1093/hmg/ddx315

By:

Khoshnan, Ali;
Sabbaugh, Adam;
Calamini, Barbara;
Marinero, Steven A.;
Dunn, Denise E.;
Jung Hyun Yoo;
Jan Ko;
Lo, Donald C.;
Patterson, Paul H.

Publication type:

Article

BDNF Mediates Neuroprotection against Oxygen-Glucose Deprivation by the Cardiac Glycoside Oleandrin.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 3, p. 963, doi. 10.1523/JNEUROSCI.2700-13.2014

By:

Van Kanegan, Michael J.;
Dong Ning He;
Dunn, Denise E.;
Peiying Yang;
Newman, Robert A.;
West, Anne E.;
Lo, Donald C.

Publication type:

Article

The quest for the cure.

Published in:

2011

By:

Stockwell, Brent R.;
Lo, Donald C.

Publication type:

Book Review

Dual activities of the anti-cancer drug candidate PBI-05204 provide neuroprotection in brain slice models for neurodegenerative diseases and stroke.

Published in:

Scientific Reports, 2016, p. 25626, doi. 10.1038/srep25626

By:

Van Kanegan, Michael J.;
Dunn, Denise E.;
Kaltenbach, Linda S.;
Shah, Bijal;
He, Dong Ning;
McCoy, Daniel D.;
Yang, Peiying;
Peng, Jiangnan;
Shen, Li;
Du, Lin;
Cichewicz, Robert H.;
Newman, Robert A.;
Lo, Donald C.

Publication type:

Article

Endocytosis and synaptic removal of NR3A-containing NMDA receptors by PACSIN1/syndapin1.

Published in:

Nature Neuroscience, 2006, v. 9, n. 5, p. 611, doi. 10.1038/nn1680

By:

Pérez-Otaño, Isabel;
Luján, Rafael;
Tavalin, Steven J.;
Plomann, Markus;
Modregger, Jan;
Xiao-Bo Liu;
Jones, Edward G.;
Heinemann, Stephen F.;
Lo, Donald C.;
Ehlers, Michael D.

Publication type:

Article

P1-146: Novel brain-slice model for APP/Aβ-induced neurodegeneration for drug discovery in Alzheimer's disease

Published in:

2008

By:

He, Dong Ning;
Schmid, Ralf;
Cho, Seongeun;
Essrich, Christian;
Dunn, Denise;
Robichaud, A.;
Malamas, M.;
Harrison, B.;
Kreft, A.;
Cole, D.;
Wood, Andrew;
Pangalos, Menelas;
Reinhart, Peter;
Lo, Donald C.

Publication type:

Abstract

Neuronal IL‐4Rα modulates neuronal apoptosis and cell viability during the acute phases of cerebral ischemia.

Published in:

FEBS Journal, 2018, v. 285, n. 15, p. 2785, doi. 10.1111/febs.14498

By:

Lee, Han Kyu;
Koh, Sehwon;
Lo, Donald C.;
Marchuk, Douglas A.

Publication type:

Article

NT-4-mediated rescue of lateral geniculate neurons from effects of monocular deprivation.

Published in:

Nature, 1995, v. 378, n. 6553, p. 189, doi. 10.1038/378189a0

By:

Riddle, David R.;
Lo, Donald C.

Publication type:

Article

CalDAG-GEFI down-regulation in the striatum as a neuroprotective change in Huntington's disease.

Published in:

Human Molecular Genetics, 2010, v. 19, n. 9, p. 1756, doi. 10.1093/hmg/ddq055

By:

Crittenden, Jill R.;
Dunn, Denise E.;
Merali, Farhan I.;
Woodman, Ben;
Yim, Michael;
Borkowska, Anna E.;
Frosch, Matthew P.;
Bates, Gillian P.;
Housman, David E.;
Lo, Donald C.;
Graybiel, Ann M.

Publication type:

Article

The Role of Neurotrophins and Activity in Regulating Cortical Dendritic Growth.

Published in:

Developmental Neuropsychology, 1999, v. 16, n. 3, p. 335, doi. 10.1207/S15326942DN1603_9

By:

McAllister, A. Kimberley;
Lo, Donald C.;
Katz, Lawrence C.

Publication type:

Article

Natural allelic variation of the IL-21 receptor modulates ischemic stroke infarct volume.

Published in:

2016

By:

Han Kyu Lee;
Sehoon Keum;
Huaxin Sheng;
Warner, David S.;
Lo, Donald C.;
Marchuk, Douglas A.;
Lee, Han Kyu;
Keum, Sehoon;
Sheng, Huaxin

Publication type:

journal article

In vitro and in vivo neuroprotective activity of the cardiac glycoside oleandrin from Nerium oleander in brain slice-based stroke models.

Published in:

Journal of Neurochemistry, 2011, v. 119, n. 4, p. 805, doi. 10.1111/j.1471-4159.2011.07439.x

By:

Dunn, Denise E.;
He, Dong Ning;
Yang, Peiying;
Johansen, Mary;
Newman, Robert A.;
Lo, Donald C.

Publication type:

Article

Identifying therapeutic targets by combining transcriptional data with ordinal clinical measurements.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00353-6

By:

Pirhaji, Leila;
Milani, Pamela;
Dalin, Simona;
Wassie, Brook T.;
Dunn, Denise E.;
Fenster, Robert J.;
Avila-Pacheco, Julian;
Greengard, Paul;
Clish, Clary B.;
Heiman, Myriam;
Lo, Donald C.;
Fraenkel, Ernest

Publication type:

Article

Abnormal degradation of the neuronal stress-protective transcription factor HSF1 in Huntington's disease.

Published in:

Nature Communications, 2017, v. 8, n. 2, p. 14405, doi. 10.1038/ncomms14405

By:

Gomez-Pastor, Rocio;
Burchfiel, Eileen T.;
Neef, Daniel W.;
Jaeger, Alex M.;
Cabiscol, Elisa;
McKinstry, Spencer U.;
Doss, Argenia;
Aballay, Alejandro;
Lo, Donald C.;
Akimov, Sergey S.;
Ross, Christopher A.;
Eroglu, Cagla;
Thiele, Dennis J.

Publication type:

Article

PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality control homeostasis.

Published in:

Science Translational Medicine, 2017, v. 9, n. 419, p. 1, doi. 10.1126/scitranslmed.aal2332

By:

Dickey, Audrey S.;
Sanchez, Dafne N.;
Arreola, Martin;
Sampat, Kunal R.;
Weiwei Fan;
Arbez, Nicolas;
Akimov, Sergey;
Van Kanegan, Michael J.;
Ohnishi, Kohta;
Gilmore-Hall, Stephen K.;
Flores, April L.;
Nguyen, Janice M.;
Lomas, Nicole;
Hsu, Cynthia L.;
Lo, Donald C.;
Ross, Christopher A.;
Masliah, Eliezer;
Evans, Ronald M.;
La Spada, Albert R.

Publication type:

Article

Inhibitors of protein disulfide isomerase suppress apoptosis induced by misfolded proteins.

Published in:

Nature Chemical Biology, 2010, v. 6, n. 12, p. 900, doi. 10.1038/nchembio.467

By:

Hoffstrom, Benjamin G.;
Kaplan, Anna;
Letso, Reka;
Schmid, Ralf S.;
Turmel, Gregory J.;
Lo, Donald C.;
Stockwell, Brent R.

Publication type:

Article

Selective inhibitors of death in mutant huntingtin cells.

Published in:

Nature Chemical Biology, 2007, v. 3, n. 2, p. 99, doi. 10.1038/nchembio852

By:

Varma, Hemant;
Voisine, Cindy;
DeMarco, C. Todd;
Cattaneo, Elena;
Lo, Donald C.;
Hart, Anne C.;
Stockwell, Brent R.

Publication type:

Article

Reduction of facial wrinkles by hydrolyzed water-soluble egg membrane associated with reduction of free radical stress and support of matrix production by dermal fibroblasts.

Published in:

Clinical, Cosmetic & Investigational Dermatology, 2016, v. 9, p. 357, doi. 10.2147/CCID.S111999

By:

Jensen, Gitte S.;
Shah, Bijal;
Holtz, Robert;
Patel, Ashok;
Lo, Donald C.

Publication type:

Article

Control of the structural landscape and neuronal proteotoxicity of mutant Huntingtin by domains flanking the polyQ tract.

Published in:

eLife, 2016, p. 1, doi. 10.7554/eLife.18065

By:

Koning Shen;
Calamini, Barbara;
Fauerbach, Jonathan A.;
Boxue Ma;
Shahmoradian, Sarah H.;
Lachapel, Ivana L. Serrano;
Wah Chiu;
Lo, Donald C.;
Frydman, Judith

Publication type:

Article

Tumoricidal stem cell therapy enables killing in novel hybrid models of heterogeneous glioblastoma.

Published in:

Neuro-Oncology, 2019, v. 21, n. 12, p. 1552, doi. 10.1093/neuonc/noz138

By:

Satterlee, Andrew B;
Dunn, Denise E;
Lo, Donald C;
Khagi, Simon;
Hingtgen, Shawn

Publication type:

Article

A New Kinetic Framework for Synaptic Vesicle Trafficking Tested in Synapsin Knock-Outs.

Published in:

Journal of Neuroscience, 2011, v. 31, n. 32, p. 11563, doi. 10.1523/JNEUROSCI.1447-11.2011

By:

Gabriel, Thomas;
García-Pérez, Elizabeth;
Mahfooz, Kashif;
Goñi, Joaquín;
Martínez-Turrillas, Rebeca;
Pérez-Otaño, Isabel;
Lo, Donald C.;
Wesseling, John F.

Publication type:

Article

Intrabodies Binding the Proline-Rich Domains of Mutant Huntingtin Increase Its Turnover and Reduce Neurotoxicity.

Published in:

Journal of Neuroscience, 2008, v. 28, n. 36, p. 9013, doi. 10.1523/JNEUROSCI.2747-08.2008

By:

Southwell, Amber L.;
Khoshnan, Ali;
Dunn, Denise E.;
Bugg, Charles W.;
Lo, Donald C.;
Patterson, Paul H.

Publication type:

Article

Natural Genetic Variation of Integrin Alpha L (<i>Itgal</i>) Modulates Ischemic Brain Injury in Stroke.

Published in:

PLoS Genetics, 2013, v. 9, n. 10, p. 1, doi. 10.1371/journal.pgen.1003807

By:

Keum, Sehoon;
Lee, Han Kyu;
Chu, Pei-Lun;
Kan, Matthew J.;
Huang, Min-Nung;
Gallione, Carol J.;
Gunn, Michael D.;
Lo, Donald C.;
Marchuk, Douglas A.

Publication type:

Article