Works matching AU Liu, Longbin

Results: 39
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    In Vivo Cerebral Imaging of Mutant Huntingtin Aggregates Using <sup>11</sup>C-CHDI-180R PET in a Nonhuman Primate Model of Huntington Disease.

    Published in:
    Journal of Nuclear Medicine, 2023, v. 64, n. 10, p. 1581, doi. 10.2967/jnumed.123.265569
    By:
    • Bertoglio, Daniele;
    • Weiss, Alison R.;
    • Liguore, William;
    • Martin, Lauren Drew;
    • Hobbs, Theodore;
    • Templon, John;
    • Srinivasan, Sathya;
    • Dominguez, Celia;
    • Munoz-Sanjuan, Ignacio;
    • Khetarpal, Vinod;
    • Verhaeghe, Jeroen;
    • Staelens, Steven;
    • Link, Jeanne;
    • Liu, Longbin;
    • Bard, Jonathan A.;
    • McBride, Jodi L.
    Publication type:
    Article
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    Validation and noninvasive kinetic modeling of [ 11 C]UCB-J PET imaging in mice.

    Published in:
    Journal of Cerebral Blood Flow & Metabolism, 2020, v. 40, n. 6, p. 1351, doi. 10.1177/0271678X19864081
    By:
    • Bertoglio, Daniele;
    • Verhaeghe, Jeroen;
    • Miranda, Alan;
    • Kertesz, Istvan;
    • Cybulska, Klaudia;
    • Korat, Špela;
    • Wyffels, Leonie;
    • Stroobants, Sigrid;
    • Mrzljak, Ladislav;
    • Dominguez, Celia;
    • Liu, Longbin;
    • Skinbjerg, Mette;
    • Munoz-Sanjuan, Ignacio;
    • Staelens, Steven
    Publication type:
    Article
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    Preclinical evaluation of the novel [<sup>18</sup>F]CHDI-650 PET ligand for non-invasive quantification of mutant huntingtin aggregates in Huntington's disease.

    Published in:
    European Journal of Nuclear Medicine & Molecular Imaging, 2024, v. 52, n. 1, p. 122, doi. 10.1007/s00259-024-06880-x
    By:
    • Zajicek, Franziska;
    • Verhaeghe, Jeroen;
    • De Lombaerde, Stef;
    • Van Eetveldt, Annemie;
    • Miranda, Alan;
    • Munoz-Sanjuan, Ignacio;
    • Dominguez, Celia;
    • Khetarpal, Vinod;
    • Bard, Jonathan;
    • Liu, Longbin;
    • Staelens, Steven;
    • Bertoglio, Daniele
    Publication type:
    Article
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    Biodistribution and dosimetry in human healthy volunteers of the PET radioligands [<sup>11</sup>C]CHDI-00485180-R and [<sup>11</sup>C]CHDI-00485626, designed for quantification of cerebral aggregated mutant huntingtin.

    Published in:
    European Journal of Nuclear Medicine & Molecular Imaging, 2022, v. 50, n. 1, p. 48, doi. 10.1007/s00259-022-05945-z
    By:
    • Delva, Aline;
    • Koole, Michel;
    • Serdons, Kim;
    • Bormans, Guy;
    • Liu, Longbin;
    • Bard, Jonathan;
    • Khetarpal, Vinod;
    • Dominguez, Celia;
    • Munoz-Sanjuan, Ignacio;
    • Wood, Andrew;
    • Skinbjerg, Mette;
    • Wang, Yuchuan;
    • Vandenberghe, Wim;
    • Van Laere, Koen
    Publication type:
    Article
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    Longitudinal preclinical evaluation of the novel radioligand [11C]CHDI-626 for PET imaging of mutant huntingtin aggregates in Huntington's disease.

    Published in:
    European Journal of Nuclear Medicine & Molecular Imaging, 2022, v. 49, n. 4, p. 1166, doi. 10.1007/s00259-021-05578-8
    By:
    • Bertoglio, Daniele;
    • Verhaeghe, Jeroen;
    • Miranda, Alan;
    • Wyffels, Leonie;
    • Stroobants, Sigrid;
    • Mrzljak, Ladislav;
    • Khetarpal, Vinod;
    • Skinbjerg, Mette;
    • Liu, Longbin;
    • Dominguez, Celia;
    • Munoz-Sanjuan, Ignacio;
    • Bard, Jonathan;
    • Staelens, Steven
    Publication type:
    Article
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    A Diels-Alder Route to [5]- and [6]-Helicenes.

    Published in:
    Angewandte Chemie International Edition, 1992, v. 31, n. 8, p. 1093, doi. 10.1002/anie.199210931
    By:
    • Willmore, Nikolaos D.;
    • Liu, Longbin;
    • Katz, Thomas J.
    Publication type:
    Article
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    Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors.

    Published in:
    Nature, 2013, v. 504, n. 7480, p. 437, doi. 10.1038/nature12724
    By:
    • Lloyd, David J.;
    • St Jean, David J.;
    • Kurzeja, Robert J. M.;
    • Wahl, Robert C.;
    • Michelsen, Klaus;
    • Cupples, Rod;
    • Chen, Michelle;
    • Wu, John;
    • Sivits, Glenn;
    • Helmering, Joan;
    • Komorowski, Renée;
    • Ashton, Kate S.;
    • Pennington, Lewis D.;
    • Fotsch, Christopher;
    • Vazir, Mukta;
    • Chen, Kui;
    • Chmait, Samer;
    • Zhang, Jiandong;
    • Liu, Longbin;
    • Norman, Mark H.
    Publication type:
    Article
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    Drug Repurposing: The Anthelmintics Niclosamide and Nitazoxanide Are Potent TMEM16A Antagonists That Fully Bronchodilate Airways.

    Published in:
    Frontiers in Pharmacology, 2019, p. N.PAG, doi. 10.3389/fphar.2019.00051
    By:
    • Miner, Kent;
    • Labitzke, Katja;
    • Liu, Benxian;
    • Wang, Paul;
    • Henckels, Kathryn;
    • Gaida, Kevin;
    • Elliott, Robin;
    • Chen, Jian Jeffrey;
    • Liu, Longbin;
    • Leith, Anh;
    • Trueblood, Esther;
    • Hensley, Kelly;
    • Xia, Xing-Zhong;
    • Homann, Oliver;
    • Bennett, Brian;
    • Fiorino, Mike;
    • Whoriskey, John;
    • Yu, Gang;
    • Escobar, Sabine;
    • Wong, Min
    Publication type:
    Article
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    Development of a ligand for in vivo imaging of mutant huntingtin in Huntington's disease.

    Published in:
    Science Translational Medicine, 2022, v. 14, n. 630, p. 1, doi. 10.1126/scitranslmed.abm3682
    By:
    • Bertoglio, Daniele;
    • Bard, Jonathan;
    • Hessmann, Manuela;
    • Liu, Longbin;
    • Gärtner, Annette;
    • De Lombaerde, Stef;
    • Huscher, Britta;
    • Zajicek, Franziska;
    • Miranda, Alan;
    • Peters, Finn;
    • Herrmann, Frank;
    • Schaertl, Sabine;
    • Vasilkovska, Tamara;
    • Brown, Christopher J.;
    • Johnson, Peter D.;
    • Prime, Michael E.;
    • Mills, Matthew R.;
    • Van der Linden, Annemie;
    • Mrzljak, Ladislav;
    • Khetarpal, Vinod
    Publication type:
    Article
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