Works by Littman, Dan R.

Results: 75

Natural resistance to HIV?

Published in:

Nature, 1996, v. 382, n. 6593, p. 668, doi. 10.1038/382668a0

By:

Hill, C. Mark;
Littman, Dan R.

Publication type:

Article

Helper T-cell development in the absence of CD4-p56lck association.

Published in:

Nature, 1993, v. 364, n. 6439, p. 729, doi. 10.1038/364729a0

By:

Killeen, Nigel;
Littman, Dan R.

Publication type:

Article

Nramp1 expression by dendritic cells modulates inflammatory responses during Salmonella Typhimurium infection.

Published in:

Cellular Microbiology, 2008, v. 10, n. 8, p. 1646, doi. 10.1111/j.1462-5822.2008.01155.x

By:

Valdez, Yanet;
Diehl, Gretchen E.;
Vallance, Bruce A.;
Grassl, Guntram A.;
Guttman, Julian A.;
Brown, Nat F.;
Rosenberger, Carrie M.;
Littman, Dan R.;
Gros, Philippe;
Finlay, B. Brett

Publication type:

Article

Inhibition of thymocyte negative selection by T cell receptor antagonist peptides.

Published in:

European Journal of Immunology, 1996, v. 26, n. 3, p. 532, doi. 10.1002/eji.1830260305

By:

Williams, Owen;
Tanaka, Yujiro;
Bix, Mark;
Murdjeva, Marianna;
Littman, Dan R.;
Kioussis, Dimitris

Publication type:

Article

Disruption of CD8-dependent negative and positive selection of thymocytes is correlated with a decreased association between CD8 and the protein tyrosine kinase, p56 lck.

Published in:

European Journal of Immunology, 1992, v. 22, n. 3, p. 735, doi. 10.1002/eji.1830220317

By:

van Oers, Nicolai S. C.;
Garvin, Alex M.;
Davis, Craig B.;
Forbush, Katherine A.;
Carlow, Douglas A.;
Littman, Dan R.;
Perlmutter, Roger M.;
Teh, Hung-Sia

Publication type:

Article

A rare intestinal infection with systemic effects.

Published in:

2012

By:

Longman, Randy S;
Moreira, Roger K;
Littman, Dan R;
Green, Peter HR;
Sethi, Amrita

Publication type:

Journal Article

A Rare Intestinal Infection with Systemic Effects.

Published in:

2012

By:

Longman, Randy S.;
Moreira, Roger K.;
Littman, Dan R.;
R. Green, Peter H.;
Sethi, Amrita

Publication type:

Case Study

Lung eosinophils elicited during allergic and acute aspergillosis express RORɣt and IL-23R but do not require IL-23 for IL-17 production.

Published in:

PLoS Pathogens, 2021, v. 17, n. 8, p. 1, doi. 10.1371/journal.ppat.1009891

By:

Yadav, Bhawna;
Specht, Charles A.;
Lee, Chrono K.;
Pokrovskii, Maria;
Huh, Jun R.;
Littman, Dan R.;
Levitz, Stuart M.

Publication type:

Article

After Hrs with HIV.

Published in:

Journal of Cell Biology, 2003, v. 162, n. 3, p. 371, doi. 10.1083/jcb.200307062

By:

Amara, Ali;
Littman, Dan R.

Publication type:

Article

Stage-specific epigenetic regulation of CD4 expression by coordinated enhancer elements during T cell development.

Published in:

Nature Communications, 2018, p. 1, doi. 10.1038/s41467-018-05834-w

By:

Issuree, Priya D.;
Day, Kenneth;
Au, Christy;
Ramya Raviram;
Zappile, Paul;
Skok, Jane A.;
Hai-Hui Xue;
Myers, Richard M.;
Littman, Dan R.

Publication type:

Article

The Chemokine Stromal Cell-Derived Factor-1 Promotes the Survival of Embryonic Retinal Ganglion Cells.

Published in:

Journal of Neuroscience, 2003, v. 23, n. 11, p. 4601, doi. 10.1523/JNEUROSCI.23-11-04601.2003

By:

Chalasani, Sreekanth H.;
Baribaud, Frederic;
Coughlan, Christine M.;
Sunshine, Mary J.;
Lee, Virginia M. Y.;
Doms, Robert W.;
Littman, Dan R.;
Raper, Jonathan A.

Publication type:

Article

Deciphering the regulatory landscape of fetal and adult γδ T‐cell development at single‐cell resolution.

Published in:

EMBO Journal, 2020, v. 39, n. 13, p. 1, doi. 10.15252/embj.2019104159

By:

Sagar;
Pokrovskii, Maria;
Herman, Josip S;
Naik, Shruti;
Sock, Elisabeth;
Zeis, Patrice;
Lausch, Ute;
Wegner, Michael;
Tanriver, Yakup;
Littman, Dan R;
Grün, Dominic

Publication type:

Article

The neuronal chemokine CX3CL1/fractalkine selectively recruits NK cells that modify experimental autoimmune encephalomyelitis within the central nervous system.

Published in:

FASEB Journal, 2006, v. 20, n. 7, p. 896, doi. 10.1096/fj.05-5465com

By:

DeRen Huang;
Fu-Dong Shi;
Jung, Steffen;
Pien, Gary C.;
Jintang Wang;
Salazar-Mather, Thais P.;
He, Toby T.;
Weaver, Jennifer T.;
Ljunggren, Hans-Gustaf;
Biron, Christine A.;
Littman, Dan R.;
Ransohoff, Richard M.

Publication type:

Article

Sparse and Compositionally Robust Inference of Microbial Ecological Networks.

Published in:

PLoS Computational Biology, 2015, v. 11, n. 5, p. 1, doi. 10.1371/journal.pcbi.1004226

By:

Kurtz, Zachary D.;
Müller, Christian L.;
Miraldi, Emily R.;
Littman, Dan R.;
Blaser, Martin J.;
Bonneau, Richard A.

Publication type:

Article

Microbiota restricts trafficking of bacteria to mesenteric lymph nodes by CX3CR1hi cells.

Published in:

Nature, 2013, v. 494, n. 7435, p. 116, doi. 10.1038/nature11809

By:

Diehl, Gretchen E.;
Longman, Randy S.;
Zhang, Jing-Xin;
Breart, Beatrice;
Galan, Carolina;
Cuesta, Adolfo;
Schwab, Susan R.;
Littman, Dan R.

Publication type:

Article

Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity.

Published in:

Nature, 2011, v. 472, n. 7344, p. 486, doi. 10.1038/nature09978

By:

Huh, Jun R.;
Leung, Monica W. L.;
Pengxiang Huang;
Ryan, Daniel A.;
Krout, Michael R.;
Malapaka, Raghu R. V.;
Chow, Jonathan;
Manel, Nicolas;
Ciofani, Maria;
Kim, Sangwon V.;
Cuesta, Adolfo;
Santori, Fabio R.;
Lafaille, Juan J.;
Xu, H. Eric;
Gin, David Y.;
Rastinejad, Fraydoon;
Littman, Dan R.

Publication type:

Article

A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells.

Published in:

2011

By:

Manel, Nicolas;
Hogstad, Brandon;
Wang, Yaming;
Levy, David E.;
Unutmaz, Derya;
Littman, Dan R.

Publication type:

Correction Notice

A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells.

Published in:

Nature, 2010, v. 467, n. 7312, p. 214, doi. 10.1038/nature09337

By:

Manel, Nicolas;
Hogstad, Brandon;
Wang, Yaming;
Levy, David E.;
Unutmaz, Derya;
Littman, Dan R.

Publication type:

Article

Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology.

Published in:

Nature, 2010, v. 464, n. 7293, p. 1371, doi. 10.1038/nature08949

By:

Buonocore, Sofia;
Ahern, Philip P.;
Uhlig, Holm H.;
Ivanov, Ivaylo I.;
Littman, Dan R.;
Malo, Kevin J.;
Powrie, Fiona

Publication type:

Article

The SDF-1/CXCR4 pathway and the development of the cerebellar system.

Published in:

European Journal of Neuroscience, 2005, v. 22, n. 8, p. 1831, doi. 10.1111/j.1460-9568.2005.04378.x

By:

Vilz, Tim O.;
Moepps, Barbara;
Engele, Jürgen;
Molly, Sabine;
Littman, Dan R.;
Schilling, Karl

Publication type:

Article

Epigenetic silencing of CD4 in T cells committed to the cytotoxic lineage.

Published in:

Nature Genetics, 2001, v. 29, n. 3, p. 332, doi. 10.1038/ng750

By:

Zou, Yong-Rui;
Sunshine, Mary-Jean;
Taniuchi, Ichiro;
Hatam, Farah;
Killeen, Nigel;
Littman, Dan R.

Publication type:

Article

Harnessing CD4+ T cell responses in HIV vaccine development.

Published in:

Nature Medicine, 2013, v. 19, n. 2, p. 143, doi. 10.1038/nm.3054

By:

Streeck, Hendrik;
D'Souza, M Patricia;
Littman, Dan R;
Crotty, Shane

Publication type:

Article

Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E.

Published in:

Nature Medicine, 2003, v. 9, n. 1, p. 61, doi. 10.1038/nm810

By:

Huo, Yuqing;
Schober, Andreas;
Forlow, S. Bradley;
Smith, David F.;
Hyman, Matthew Craig;
Jung, Steffen;
Littman, Dan R.;
Weber, Christian;
Ley, Klaus

Publication type:

Article

Intravascular Immune Surveillance by CXCR6+ NKT Cells Patrolling Liver Sinusoids.

Published in:

PLoS Biology, 2005, v. 3, n. 4, p. 1, doi. 10.1371/journal.pbio.0030113

By:

Geissmann, Frederic;
Cameron, Thomas O;
Sidobre, Stephane;
Manlongat, Natasha;
Kronenberg, Mitchell;
Briskin, Michael J;
Dustin, Michael L;
Littman, Dan R

Publication type:

Article

Intravascular Immune Surveillance by CXCR6+ NKT Cells Patrolling Liver Sinusoids.

Published in:

PLoS Biology, 2005, v. 3, n. 4, p. 650, doi. 10.1371/journal.pbio.0030113

By:

Geissmann, Frederic;
Cameron, Thomas O.;
Sidobre, Stephane;
Manlongat, Natasha;
Kronenberg, Mitchell;
Briskin, Michael J.;
Dustin, Michael L.;
Littman, Dan R.

Publication type:

Article

Focused specificity of intestinal TH17 cells towards commensal bacterial antigens.

Published in:

Nature, 2014, v. 510, n. 7503, p. 152, doi. 10.1038/nature13279

By:

Yang, Yi;
Torchinsky, Miriam B.;
Gobert, Michael;
Xiong, Huizhong;
Xu, Mo;
Linehan, Jonathan L.;
Alonzo, Francis;
Ng, Charles;
Chen, Alessandra;
Lin, Xiyao;
Sczesnak, Andrew;
Liao, Jia-Jun;
Torres, Victor J.;
Jenkins, Marc K.;
Lafaille, Juan J.;
Littman, Dan R.

Publication type:

Article

Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity.

Published in:

Nature, 2014, v. 508, n. 7494, p. 123, doi. 10.1038/nature13158

By:

van de Pavert, Serge A.;
Ferreira, Manuela;
Domingues, Rita G.;
Ribeiro, Hélder;
Molenaar, Rosalie;
Moreira-Santos, Lara;
Almeida, Francisca F.;
Ibiza, Sales;
Barbosa, Inês;
Goverse, Gera;
Labão-Almeida, Carlos;
Godinho-Silva, Cristina;
Konijn, Tanja;
Schooneman, Dennis;
O'Toole, Tom;
Mizee, Mark R.;
Habani, Yasmin;
Haak, Esther;
Santori, Fabio R.;
Littman, Dan R.

Publication type:

Article

Provocateurs of autoimmunity within the gut microbiota.

Published in:

Science Translational Medicine, 2022, v. 14, n. 668, p. 1, doi. 10.1126/scitranslmed.add3901

By:

Upadhyay, Rabi;
Littman, Dan R.

Publication type:

Article

The Kinase-dependent Function of Lck in T-Cell Activation Requires an Intact Site for Tyrosine Autophosphorylationa.

Published in:

Annals of the New York Academy of Sciences, 1995, v. 766, n. 1, p. 99, doi. 10.1111/j.1749-6632.1995.tb26655.x

By:

XU, HUA;
LITTMAN, DAN R.

Publication type:

Article

Short- and long-term effects of oral vancomycin on the human intestinal microbiota.

Published in:

2017

By:

Isaac, Sandrine;
Scher, Jose U.;
Djukovic, Ana;
Jiménez, Nuria;
Littman, Dan R.;
Abramson, Steven B.;
Pamer, Eric G.;
Ubeda, Carles

Publication type:

journal article

Transmembrane domain–driven PD-1 dimers mediate T cell inhibition.

Published in:

Science Immunology, 2024, v. 9, n. 93, p. 1, doi. 10.1126/sciimmunol.ade6256

By:

Philips, Elliot A.;
Liu, Jia;
Kvalvaag, Audun;
Mørch, Alexander M.;
Tocheva, Anna S.;
Ng, Charles;
Liang, Hong;
Ahearn, Ian M.;
Pan, Ruimin;
Luo, Christina C.;
Leithner, Alexander;
Qin, Zhihua;
Zhou, Yong;
Garcia-España, Antonio;
Mor, Adam;
Littman, Dan R.;
Dustin, Michael L.;
Wang, Jun;
Kong, Xiang-Peng

Publication type:

Article

c-MAF–dependent perivascular macrophages regulate diet-induced metabolic syndrome.

Published in:

Science Immunology, 2021, v. 6, n. 64, p. 1, doi. 10.1126/sciimmunol.abg7506

By:

Moura Silva, Hernandez;
Kitoko, Jamil Zola;
Queiroz, Camila Pereira;
Kroehling, Lina;
Matheis, Fanny;
Yang, Katharine Lu;
Reis, Bernardo S.;
Ren-Fielding, Christine;
Littman, Dan R.;
Bozza, Marcelo Torres;
Mucida, Daniel;
Lafaille, Juan J.

Publication type:

Article

ATP mediates rapid microglial response to local brain injury in vivo.

Published in:

Nature Neuroscience, 2005, v. 8, n. 6, p. 752, doi. 10.1038/nn1472

By:

Davalos, Dimitrios;
Grutzendler, Jaime;
Guang Yang;
Kim, Jiyun V.;
Yi Zuo;
Jung, Steffen;
Littman, Dan R.;
Dustin, Michael L.;
Gan, Wen-Biao

Publication type:

Article

Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes.

Published in:

Nature, 2002, v. 418, n. 6894, p. 195, doi. 10.1038/nature00876

By:

Chi, Tian H.;
Mimi Wan;
Keji Zhao;
Taniuchi, Ichiro;
Lei Chen;
Littman, Dan R.;
Crabtree, Gerald R.

Publication type:

Article

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development.

Published in:

Nature, 1998, v. 393, n. 6685, p. 595, doi. 10.1038/31269

By:

Zou, Yong-Rui;
Kottmann, Andreas H.;
Kuroda, Masahiko;
Taniuchi, Ichiro;
Littman, Dan R.

Publication type:

Article

The Function of the CD4 Coreceptor in the Development of T Cells.

Published in:

International Reviews of Immunology, 1995, v. 13, n. 1, p. 15, doi. 10.3109/08830189509061735

By:

Killeen, Nigel;
Littman, Dan R.

Publication type:

Article

Heritable Gene Regulation in the CD4:CD8 T Cell Lineage Choice.

Published in:

Frontiers in Immunology, 2017, v. 8, p. 1, doi. 10.3389/fimmu.2017.00291

By:

Issuree, Priya D. A.;
Ng, Charles P.;
Littman, Dan R.

Publication type:

Article

Drosha regulates neurogenesis by controlling Neurogenin 2 expression independent of microRNAs.

Published in:

Nature Neuroscience, 2012, v. 15, n. 7, p. 962, doi. 10.1038/nn.3139

By:

Knuckles, Philip;
Vogt, Miriam A;
Lugert, Sebastian;
Milo, Marta;
Chong, Mark M W;
Hautbergue, Guillaume M;
Wilson, Stuart A;
Littman, Dan R;
Taylor, Verdon

Publication type:

Article

Control of microglial neurotoxicity by the fractalkine receptor.

Published in:

Nature Neuroscience, 2006, v. 9, n. 7, p. 917, doi. 10.1038/nn1715

By:

Cardona, Astrid E.;
Pioro, Erik P.;
Sasse, Margaret E.;
Kostenko, Volodymyr;
Cardona, Sandra M.;
Dijkstra, Ineke M.;
Huang, DeRen;
Kidd, Grahame;
Dombrowski, Stephen;
Dutta, RanJan;
Lee, Jar-Chi;
Cook, Donald N.;
Jung, Steffen;
Lira, Sergio A.;
Littman, Dan R.;
Ransohoff, Richard M.

Publication type:

Article

Myd88 Is Required for an Antibody Response to Retroviral Infection.

Published in:

PLoS Pathogens, 2009, v. 5, n. 2, p. 1, doi. 10.1371/journal.ppat.1000298

By:

Browne, Edward P.;
Littman, Dan R.

Publication type:

Article

Arrangements and Rearrangements of the Human T-cell Receptor Gamma Genea.

Published in:

Annals of the New York Academy of Sciences, 1987, v. 511, n. 1, p. 232, doi. 10.1111/j.1749-6632.1987.tb36251.x

By:

PELICCI, PIER GIUSEPPE;
NERI, ANTONINO;
KNOWLES, DANIEL M.;
LITTMAN, DAN R.;
DALLA-FAVERA, RICCARDO;
SUBAR, MILAYNA

Publication type:

Article

TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function.

Published in:

Nature, 2008, v. 453, n. 7192, p. 236, doi. 10.1038/nature06878

By:

Liang Zhou;
Lopes, Jared E.;
Chong, Mark M. W.;
Ivanov, Ivaylo I.;
Min, Roy;
Victora, Gabriel D.;
Yuelei Shen;
Du, Jianguang;
Rubtsov, Yuri P.;
Rudensky, Alexander Y.;
Ziegler, Steven F.;
Littman, Dan R.

Publication type:

Article

Disrupting Hepatocyte Cyp51 from Cholesterol Synthesis Leads to Progressive Liver Injury in the Developing Mouse and Decreases RORC Signalling.

Published in:

Scientific Reports, 2017, p. 40775, doi. 10.1038/srep40775

By:

Urlep, Žiga;
Lorbek, Gregor;
Perše, Martina;
Jeruc, Jera;
Juvan, Peter;
Matz-Soja, Madlen;
Gebhardt, Rolf;
Björkhem, Ingemar;
Hall, Jason A.;
Bonneau, Richard;
Littman, Dan R.;
Rozman, Damjana

Publication type:

Article

Mice Transgenic for CD4-Specific Human CD4, CCR5 and Cyclin T1 Expression: A New Model for Investigating HIV-1 Transmission and Treatment Efficacy

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063537

By:

Seay, Kieran;
Qi, Xiaohua;
Zheng, Jian Hua;
Zhang, Cong;
Chen, Ken;
Dutta, Monica;
Deneroff, Kathryn;
Ochsenbauer, Christina;
Kappes, John C.;
Littman, Dan R.;
Goldstein, Harris

Publication type:

Article

Impact of the TCR Signal on Regulatory T Cell Homeostasis, Function, and Trafficking.

Published in:

PLoS ONE, 2009, v. 4, n. 8, p. 1, doi. 10.1371/journal.pone.0006580

By:

Joong Kyu Kim;
Klinger, Mark;
Benjamin, Jonathan;
Yuanyuan Xiao;
Erle, David J.;
Littman, Dan R.;
Killeen, Nigel

Publication type:

Article

Relief of Preintegration Inhibition and Characterization of Additional Blocks for HIV Replication in Primary Mouse T Cells.

Published in:

PLoS ONE, 2008, v. 3, n. 4, p. 1, doi. 10.1371/journal.pone.0002035

By:

Jing-xin Zhang;
Diehl, Gretchen E.;
Littman, Dan R.

Publication type:

Article

Lineage Diversion of T Cell Receptor Transgenic Thymocytes Revealed by Lineage Fate Mapping.

Published in:

PLoS ONE, 2008, v. 3, n. 1, p. 1, doi. 10.1371/journal.pone.0001512

By:

Egawa, Takeshi;
Kreslavsky, Taras;
Littman, Dan R.;
von Boehmer, Harald

Publication type:

Article

The inducible deletion of Drosha and microRNAs in mature podocytes results in a collapsing glomerulopathy.

Published in:

Kidney International, 2011, v. 80, n. 7, p. 719, doi. 10.1038/ki.2011.122

By:

Zhdanova, Olga;
Srivastava, Shekhar;
Di, Lie;
Li, Zhai;
Tchelebi, Leila;
Dworkin, Sara;
Johnstone, Duncan B;
Zavadil, Jiri;
Chong, Mark M;
Littman, Dan R;
Holzman, Lawrence B;
Barisoni, Laura;
Skolnik, Edward Y

Publication type:

Article

RUNX proteins in transcription factor networks that regulate T-cell lineage choice.

Published in:

2009

By:

Collins, Amélie;
Littman, Dan R.;
Taniuchi, Ichiro;
Collins, Amélie

Publication type:

journal article

The role of the nuclear hormone receptor RORγt in the development of lymph nodes and Peyer's patches.

Published in:

Immunological Reviews, 2003, v. 195, n. 1, p. 81, doi. 10.1034/j.1600-065X.2003.00074.x

By:

Eberl, Gerard;
Littman, Dan R.

Publication type:

Article