Works by Littman, Dan R.

Results: 75

Intravascular Immune Surveillance by CXCR6+ NKT Cells Patrolling Liver Sinusoids.

Published in:

PLoS Biology, 2005, v. 3, n. 4, p. 1, doi. 10.1371/journal.pbio.0030113

By:

Geissmann, Frederic;
Cameron, Thomas O;
Sidobre, Stephane;
Manlongat, Natasha;
Kronenberg, Mitchell;
Briskin, Michael J;
Dustin, Michael L;
Littman, Dan R

Publication type:

Article

Intravascular Immune Surveillance by CXCR6+ NKT Cells Patrolling Liver Sinusoids.

Published in:

PLoS Biology, 2005, v. 3, n. 4, p. 650, doi. 10.1371/journal.pbio.0030113

By:

Geissmann, Frederic;
Cameron, Thomas O.;
Sidobre, Stephane;
Manlongat, Natasha;
Kronenberg, Mitchell;
Briskin, Michael J.;
Dustin, Michael L.;
Littman, Dan R.

Publication type:

Article

CXCR4 acts as a costimulator during thymic β-selection.

Published in:

Nature Immunology, 2010, v. 11, n. 2, p. 162, doi. 10.1038/ni.1830

By:

Trampont, Paul C.;
Tosello-Trampont, Annie-Carole;
Shen, Yuelei;
Duley, Amanda K.;
Sutherland, Ann E.;
Bender, Timothy P.;
Littman, Dan R.;
Ravichandran, Kodi S.

Publication type:

Article

Runx-CBFβ complexes control expression of the transcription factor Foxp3 in regulatory T cells.

Published in:

Nature Immunology, 2009, v. 10, n. 11, p. 1170, doi. 10.1038/ni.1795

By:

Rudra, Dipayan;
Egawa, Takeshi;
Chong, Mark M. W.;
Treuting, Piper;
Littman, Dan R.;
Rudensky, Alexander Y.

Publication type:

Article

Influence of the transcription factor RORγt on the development of NKp46+ cell populations in gut and skin.

Published in:

Nature Immunology, 2009, v. 10, n. 1, p. 75, doi. 10.1038/ni.1681

By:

Luci, Carmelo;
Reynders, Ana;
Ivanov, Ivaylo I;
Cognet, Celine;
Chiche, Laurent;
Chasson, Lionel;
Hardwigsen, Jean;
Anguiano, Esperanza;
Banchereau, Jacques;
Chaussabel, Damien;
Dalod, Marc;
Littman, Dan R;
Vivier, Eric;
Tomasello, Elena

Publication type:

Article

ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage.

Published in:

Nature Immunology, 2008, v. 9, n. 10, p. 1131, doi. 10.1038/ni.1652

By:

Egawa, Takeshi;
Littman, Dan R

Publication type:

Article

Restoration of lymphoid organ integrity through the interaction of lymphoid tissue–inducer cells with stroma of the T cell zone.

Published in:

Nature Immunology, 2008, v. 9, n. 6, p. 667, doi. 10.1038/ni.1605

By:

Scandella, Elke;
Bolinger, Beatrice;
Lattmann, Evelyn;
Miller, Simone;
Favre, Stéphanie;
Littman, Dan R;
Finke, Daniela;
Luther, Sanjiv A;
Junt, Tobias;
Ludewig, Burkhard

Publication type:

Article

The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt.

Published in:

Nature Immunology, 2008, v. 9, n. 6, p. 641, doi. 10.1038/ni.1610

By:

Manel, Nicolas;
Unutmaz, Derya;
Littman, Dan R

Publication type:

Article

IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways.

Published in:

Nature Immunology, 2007, v. 8, n. 9, p. 967, doi. 10.1038/ni1488

By:

Zhou, Liang;
Ivanov, Ivaylo I;
Spolski, Rosanne;
Min, Roy;
Shenderov, Kevin;
Egawa, Takeshi;
Levy, David E;
Leonard, Warren J;
Littman, Dan R

Publication type:

Article

An essential function for the nuclear receptor ROR?t in the generation of fetal lymphoid tissue inducer cells.

Published in:

Nature Immunology, 2004, v. 5, n. 1, p. 64, doi. 10.1038/ni1022

By:

Eberl, Gérard;
Marmon, Shana;
Sunshine, Mary-Jean;
Rennert, Paul D.;
Yongwon Choi;
Littman, Dan R.

Publication type:

Article

Regulation of the TCRa repertoire by the survival window of CD4+CD8+ thymocytes.

Published in:

Nature Immunology, 2002, v. 3, n. 5, p. 469, doi. 10.1038/ni791

By:

Guo, Jian;
Hawwari, Abbas;
Li, Hong;
Sun, Zuoming;
Mahanta, Sanjeev K.;
Littman, Dan R.;
Krangel, Michael S.;
He, You-Wen

Publication type:

Article

Inactivation of Notch1 in immature thymocytes does not perturb CD4 or CD8 T cell development.

Published in:

Nature Immunology, 2001, v. 2, n. 3, p. 235, doi. 10.1038/85294

By:

Wolfer, Anita;
Bakker, Talitha;
Wilson, Anne;
Nicolas, Michael;
Ioannidis, Vassilios;
Littman, Dan R.;
Wilson, Christopher B.;
Held, Werner;
MacDonald, H. Robson;
Radtke, Freddy

Publication type:

Article

The Function of the CD4 Coreceptor in the Development of T Cells.

Published in:

International Reviews of Immunology, 1995, v. 13, n. 1, p. 15, doi. 10.3109/08830189509061735

By:

Killeen, Nigel;
Littman, Dan R.

Publication type:

Article

TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function.

Published in:

Nature, 2008, v. 453, n. 7192, p. 236, doi. 10.1038/nature06878

By:

Liang Zhou;
Lopes, Jared E.;
Chong, Mark M. W.;
Ivanov, Ivaylo I.;
Min, Roy;
Victora, Gabriel D.;
Yuelei Shen;
Du, Jianguang;
Rubtsov, Yuri P.;
Rudensky, Alexander Y.;
Ziegler, Steven F.;
Littman, Dan R.

Publication type:

Article

CD4 expression in effector T cells depends on DNA demethylation over a developmentally established stimulus-responsive element.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28914-4

By:

Teghanemt, Athmane;
Pulipati, Priyanjali;
Misel-Wuchter, Kara;
Day, Kenneth;
Yorek, Matthew S.;
Yi, Ren;
Keen, Henry L.;
Au, Christy;
Maretzky, Thorsten;
Gurung, Prajwal;
Littman, Dan R.;
Issuree, Priya D.

Publication type:

Article

The Chemokine Stromal Cell-Derived Factor-1 Promotes the Survival of Embryonic Retinal Ganglion Cells.

Published in:

Journal of Neuroscience, 2003, v. 23, n. 11, p. 4601, doi. 10.1523/JNEUROSCI.23-11-04601.2003

By:

Chalasani, Sreekanth H.;
Baribaud, Frederic;
Coughlan, Christine M.;
Sunshine, Mary J.;
Lee, Virginia M. Y.;
Doms, Robert W.;
Littman, Dan R.;
Raper, Jonathan A.

Publication type:

Article

Epigenetic silencing of CD4 in T cells committed to the cytotoxic lineage.

Published in:

Nature Genetics, 2001, v. 29, n. 3, p. 332, doi. 10.1038/ng750

By:

Zou, Yong-Rui;
Sunshine, Mary-Jean;
Taniuchi, Ichiro;
Hatam, Farah;
Killeen, Nigel;
Littman, Dan R.

Publication type:

Article

PKC-ϑ knockout mice are protected from fat-induced insulin resistance.

Published in:

Journal of Clinical Investigation, 2004, v. 114, n. 6, p. 823, doi. 10.1172/JCI200422230

By:

Kim, Jason K.;
Fillmore, Jonathan J.;
Sunshine, Mary Jean;
Albrecht, Bjoern;
Higashimori, Takamasa;
Kim, Dong-wook;
Liu, Zhen-xiang;
Soos, Timothy J.;
Cline, Gary W.;
O'brien, William R.;
Littman, Dan R.;
Shulman, Gerald I.

Publication type:

Article

PKC-theta knockout mice are protected from fat-induced insulin resistance.

Published in:

2004

By:

Kim, Jason K;
Fillmore, Jonathan J;
Sunshine, Mary Jean;
Albrecht, Bjoern;
Higashimori, Takamasa;
Kim, Dong-Wook;
Liu, Zhen-Xiang;
Soos, Timothy J;
Cline, Gary W;
O'Brien, William R;
Littman, Dan R;
Shulman, Gerald I

Publication type:

journal article

Small molecule inhibitors of RORγt: Targeting Th17 cells and other applications.

Published in:

European Journal of Immunology, 2012, v. 42, n. 9, p. 2232, doi. 10.1002/eji.201242740

By:

Huh, Jun R.;
Littman, Dan R.

Publication type:

Article

A rare intestinal infection with systemic effects.

Published in:

2012

By:

Longman, Randy S;
Moreira, Roger K;
Littman, Dan R;
Green, Peter HR;
Sethi, Amrita

Publication type:

Journal Article

A Rare Intestinal Infection with Systemic Effects.

Published in:

2012

By:

Longman, Randy S.;
Moreira, Roger K.;
Littman, Dan R.;
R. Green, Peter H.;
Sethi, Amrita

Publication type:

Case Study

Arrangements and Rearrangements of the Human T-cell Receptor Gamma Genea.

Published in:

Annals of the New York Academy of Sciences, 1987, v. 511, n. 1, p. 232, doi. 10.1111/j.1749-6632.1987.tb36251.x

By:

PELICCI, PIER GIUSEPPE;
NERI, ANTONINO;
KNOWLES, DANIEL M.;
LITTMAN, DAN R.;
DALLA-FAVERA, RICCARDO;
SUBAR, MILAYNA

Publication type:

Article

Cell-cell adhesion mediated by CD8 and MHC class I molecules.

Published in:

Nature, 1988, v. 336, n. 6194, p. 79, doi. 10.1038/336079a0

By:

Norment, Anne M.;
Salter, Russell D.;
Parham, Peter;
Engelhard, Victor H.;
Littman, Dan R.

Publication type:

Article

The envelope glycoprotein of the human immunodeficiency virus binds to the immunoglobulin-like domain of CD4.

Published in:

Nature, 1988, v. 334, n. 6178, p. 159, doi. 10.1038/334159a0

By:

Landau, Nathaniel R.;
Warton, Maria;
Littman, Dan R.

Publication type:

Article

Internalization of the human immunodeficiency virus does not require the cytoplasmic domain of CD4.

Published in:

Nature, 1988, v. 334, n. 6178, p. 162, doi. 10.1038/334162a0

By:

Bedinger, Patricia;
Moriarty, Ann;
von Borstel, Robert C.;
Donovan, Nancy J.;
Steimer, Kathelyn S.;
Littman, Dan R.

Publication type:

Article

Identification and sequence of a fourth human T cell antigen receptor chain.

Published in:

Nature, 1987, v. 330, n. 6148, p. 569, doi. 10.1038/330569a0

By:

Loh, Elwyn Y.;
Lanier, Lewis L.;
Turck, Christoph W.;
Littman, Dan R.;
Davis, Mark M.;
Chien, Yueh-Hsiu;
Weiss, Arthur

Publication type:

Article

Unusual intron in the immunoglobulin domain of the newly isolated murine CD4 (L3T4) gene.

Published in:

Nature, 1987, v. 325, n. 6103, p. 453, doi. 10.1038/325453a0

By:

Littman, Dan R.;
Gettner, Sonya N.

Publication type:

Article

RUNX proteins in transcription factor networks that regulate T-cell lineage choice.

Published in:

2009

By:

Collins, Amélie;
Littman, Dan R.;
Taniuchi, Ichiro;
Collins, Amélie

Publication type:

journal article

After Hrs with HIV.

Published in:

Journal of Cell Biology, 2003, v. 162, n. 3, p. 371, doi. 10.1083/jcb.200307062

By:

Amara, Ali;
Littman, Dan R.

Publication type:

Article

Review: Microbiome in Inflammatory Arthritis and Human Rheumatic Diseases.

Published in:

Arthritis & Rheumatology, 2016, v. 68, n. 1, p. 35, doi. 10.1002/art.39259

By:

Scher, Jose U.;
Littman, Dan R.;
Abramson, Steven B.

Publication type:

Article

Decreased Bacterial Diversity Characterizes the Altered Gut Microbiota in Patients With Psoriatic Arthritis, Resembling Dysbiosis in Inflammatory Bowel Disease.

Published in:

Arthritis & Rheumatology, 2015, v. 67, n. 1, p. 128, doi. 10.1002/art.38892

By:

Scher, Jose U.;
Ubeda, Carles;
Artacho, Alejandro;
Attur, Mukundan;
Isaac, Sandrine;
Reddy, Soumya M.;
Marmon, Shoshana;
Neimann, Andrea;
Brusca, Samuel;
Patel, Tejas;
Manasson, Julia;
Pamer, Eric G.;
Littman, Dan R.;
Abramson, Steven B.

Publication type:

Article

A Huntington's disease CAG expansion at the murine Hdh locus is unstable and associated with behavioural abnormalities in mice.

Published in:

Human Molecular Genetics, 1999, v. 8, n. 5, p. 763, doi. 10.1093/hmg/8.5.763

By:

Shelbourne, Peggy F.;
Killeen, Nigel;
Hevner, Robert F.;
Johnston, Heather M.;
Tecott, Laurence;
Lewandoski, Mark;
Ennis, Margaret;
Ramirez, Lucia;
Li, Zhen;
Iannicola, Carlo;
Littman, Dan R.;
Myers, Richard M.

Publication type:

Article

Deciphering the regulatory landscape of fetal and adult γδ T‐cell development at single‐cell resolution.

Published in:

EMBO Journal, 2020, v. 39, n. 13, p. 1, doi. 10.15252/embj.2019104159

By:

Sagar;
Pokrovskii, Maria;
Herman, Josip S;
Naik, Shruti;
Sock, Elisabeth;
Zeis, Patrice;
Lausch, Ute;
Wegner, Michael;
Tanriver, Yakup;
Littman, Dan R;
Grün, Dominic

Publication type:

Article

The role of the nuclear hormone receptor RORγt in the development of lymph nodes and Peyer's patches.

Published in:

Immunological Reviews, 2003, v. 195, n. 1, p. 81, doi. 10.1034/j.1600-065X.2003.00074.x

By:

Eberl, Gerard;
Littman, Dan R.

Publication type:

Article

Drosha regulates neurogenesis by controlling Neurogenin 2 expression independent of microRNAs.

Published in:

Nature Neuroscience, 2012, v. 15, n. 7, p. 962, doi. 10.1038/nn.3139

By:

Knuckles, Philip;
Vogt, Miriam A;
Lugert, Sebastian;
Milo, Marta;
Chong, Mark M W;
Hautbergue, Guillaume M;
Wilson, Stuart A;
Littman, Dan R;
Taylor, Verdon

Publication type:

Article

Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E.

Published in:

Nature Medicine, 2003, v. 9, n. 1, p. 61, doi. 10.1038/nm810

By:

Huo, Yuqing;
Schober, Andreas;
Forlow, S. Bradley;
Smith, David F.;
Hyman, Matthew Craig;
Jung, Steffen;
Littman, Dan R.;
Weber, Christian;
Ley, Klaus

Publication type:

Article

Myd88 Is Required for an Antibody Response to Retroviral Infection.

Published in:

PLoS Pathogens, 2009, v. 5, n. 2, p. 1, doi. 10.1371/journal.ppat.1000298

By:

Browne, Edward P.;
Littman, Dan R.

Publication type:

Article

Natural resistance to HIV?

Published in:

Nature, 1996, v. 382, n. 6593, p. 668, doi. 10.1038/382668a0

By:

Hill, C. Mark;
Littman, Dan R.

Publication type:

Article

Helper T-cell development in the absence of CD4-p56lck association.

Published in:

Nature, 1993, v. 364, n. 6439, p. 729, doi. 10.1038/364729a0

By:

Killeen, Nigel;
Littman, Dan R.

Publication type:

Article

Regulation of DNA methylation dictates Cd4 expression during the development of helper and cytotoxic T cell lineages.

Published in:

Nature Immunology, 2015, v. 16, n. 7, p. 746, doi. 10.1038/ni.3198

By:

Sellars, MacLean;
Huh, Jun R;
Day, Kenneth;
Issuree, Priya D;
Galan, Carolina;
Gobeil, Stephane;
Absher, Devin;
Green, Michael R;
Littman, Dan R

Publication type:

Article

Sparse and Compositionally Robust Inference of Microbial Ecological Networks.

Published in:

PLoS Computational Biology, 2015, v. 11, n. 5, p. 1, doi. 10.1371/journal.pcbi.1004226

By:

Kurtz, Zachary D.;
Müller, Christian L.;
Miraldi, Emily R.;
Littman, Dan R.;
Blaser, Martin J.;
Bonneau, Richard A.

Publication type:

Article

Nramp1 expression by dendritic cells modulates inflammatory responses during Salmonella Typhimurium infection.

Published in:

Cellular Microbiology, 2008, v. 10, n. 8, p. 1646, doi. 10.1111/j.1462-5822.2008.01155.x

By:

Valdez, Yanet;
Diehl, Gretchen E.;
Vallance, Bruce A.;
Grassl, Guntram A.;
Guttman, Julian A.;
Brown, Nat F.;
Rosenberger, Carrie M.;
Littman, Dan R.;
Gros, Philippe;
Finlay, B. Brett

Publication type:

Article

Stage-specific epigenetic regulation of CD4 expression by coordinated enhancer elements during T cell development.

Published in:

Nature Communications, 2018, p. 1, doi. 10.1038/s41467-018-05834-w

By:

Issuree, Priya D.;
Day, Kenneth;
Au, Christy;
Ramya Raviram;
Zappile, Paul;
Skok, Jane A.;
Hai-Hui Xue;
Myers, Richard M.;
Littman, Dan R.

Publication type:

Article

Harnessing CD4+ T cell responses in HIV vaccine development.

Published in:

Nature Medicine, 2013, v. 19, n. 2, p. 143, doi. 10.1038/nm.3054

By:

Streeck, Hendrik;
D'Souza, M Patricia;
Littman, Dan R;
Crotty, Shane

Publication type:

Article

The neuronal chemokine CX3CL1/fractalkine selectively recruits NK cells that modify experimental autoimmune encephalomyelitis within the central nervous system.

Published in:

FASEB Journal, 2006, v. 20, n. 7, p. 896, doi. 10.1096/fj.05-5465com

By:

DeRen Huang;
Fu-Dong Shi;
Jung, Steffen;
Pien, Gary C.;
Jintang Wang;
Salazar-Mather, Thais P.;
He, Toby T.;
Weaver, Jennifer T.;
Ljunggren, Hans-Gustaf;
Biron, Christine A.;
Littman, Dan R.;
Ransohoff, Richard M.

Publication type:

Article

Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes.

Published in:

Nature, 2002, v. 418, n. 6894, p. 195, doi. 10.1038/nature00876

By:

Chi, Tian H.;
Mimi Wan;
Keji Zhao;
Taniuchi, Ichiro;
Lei Chen;
Littman, Dan R.;
Crabtree, Gerald R.

Publication type:

Article

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development.

Published in:

Nature, 1998, v. 393, n. 6685, p. 595, doi. 10.1038/31269

By:

Zou, Yong-Rui;
Kottmann, Andreas H.;
Kuroda, Masahiko;
Taniuchi, Ichiro;
Littman, Dan R.

Publication type:

Article

Transmembrane domain–driven PD-1 dimers mediate T cell inhibition.

Published in:

Science Immunology, 2024, v. 9, n. 93, p. 1, doi. 10.1126/sciimmunol.ade6256

By:

Philips, Elliot A.;
Liu, Jia;
Kvalvaag, Audun;
Mørch, Alexander M.;
Tocheva, Anna S.;
Ng, Charles;
Liang, Hong;
Ahearn, Ian M.;
Pan, Ruimin;
Luo, Christina C.;
Leithner, Alexander;
Qin, Zhihua;
Zhou, Yong;
Garcia-España, Antonio;
Mor, Adam;
Littman, Dan R.;
Dustin, Michael L.;
Wang, Jun;
Kong, Xiang-Peng

Publication type:

Article

c-MAF–dependent perivascular macrophages regulate diet-induced metabolic syndrome.

Published in:

Science Immunology, 2021, v. 6, n. 64, p. 1, doi. 10.1126/sciimmunol.abg7506

By:

Moura Silva, Hernandez;
Kitoko, Jamil Zola;
Queiroz, Camila Pereira;
Kroehling, Lina;
Matheis, Fanny;
Yang, Katharine Lu;
Reis, Bernardo S.;
Ren-Fielding, Christine;
Littman, Dan R.;
Bozza, Marcelo Torres;
Mucida, Daniel;
Lafaille, Juan J.

Publication type:

Article