Works matching AU Littman, Dan R

Results: 75

Unusual intron in the immunoglobulin domain of the newly isolated murine CD4 (L3T4) gene.

Published in:

Nature, 1987, v. 325, n. 6103, p. 453, doi. 10.1038/325453a0

By:

Littman, Dan R.;
Gettner, Sonya N.

Publication type:

Article

RUNX proteins in transcription factor networks that regulate T-cell lineage choice.

Published in:

2009

By:

Collins, Amélie;
Littman, Dan R.;
Taniuchi, Ichiro;
Collins, Amélie

Publication type:

journal article

Harnessing CD4+ T cell responses in HIV vaccine development.

Published in:

Nature Medicine, 2013, v. 19, n. 2, p. 143, doi. 10.1038/nm.3054

By:

Streeck, Hendrik;
D'Souza, M Patricia;
Littman, Dan R;
Crotty, Shane

Publication type:

Article

Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E.

Published in:

Nature Medicine, 2003, v. 9, n. 1, p. 61, doi. 10.1038/nm810

By:

Huo, Yuqing;
Schober, Andreas;
Forlow, S. Bradley;
Smith, David F.;
Hyman, Matthew Craig;
Jung, Steffen;
Littman, Dan R.;
Weber, Christian;
Ley, Klaus

Publication type:

Article

Epigenetic silencing of CD4 in T cells committed to the cytotoxic lineage.

Published in:

Nature Genetics, 2001, v. 29, n. 3, p. 332, doi. 10.1038/ng750

By:

Zou, Yong-Rui;
Sunshine, Mary-Jean;
Taniuchi, Ichiro;
Hatam, Farah;
Killeen, Nigel;
Littman, Dan R.

Publication type:

Article

Myd88 Is Required for an Antibody Response to Retroviral Infection.

Published in:

PLoS Pathogens, 2009, v. 5, n. 2, p. 1, doi. 10.1371/journal.ppat.1000298

By:

Browne, Edward P.;
Littman, Dan R.

Publication type:

Article

Short- and long-term effects of oral vancomycin on the human intestinal microbiota.

Published in:

2017

By:

Isaac, Sandrine;
Scher, Jose U.;
Djukovic, Ana;
Jiménez, Nuria;
Littman, Dan R.;
Abramson, Steven B.;
Pamer, Eric G.;
Ubeda, Carles

Publication type:

journal article

CXCR4 acts as a costimulator during thymic β-selection.

Published in:

Nature Immunology, 2010, v. 11, n. 2, p. 162, doi. 10.1038/ni.1830

By:

Trampont, Paul C.;
Tosello-Trampont, Annie-Carole;
Shen, Yuelei;
Duley, Amanda K.;
Sutherland, Ann E.;
Bender, Timothy P.;
Littman, Dan R.;
Ravichandran, Kodi S.

Publication type:

Article

Runx-CBFβ complexes control expression of the transcription factor Foxp3 in regulatory T cells.

Published in:

Nature Immunology, 2009, v. 10, n. 11, p. 1170, doi. 10.1038/ni.1795

By:

Rudra, Dipayan;
Egawa, Takeshi;
Chong, Mark M. W.;
Treuting, Piper;
Littman, Dan R.;
Rudensky, Alexander Y.

Publication type:

Article

Influence of the transcription factor RORγt on the development of NKp46+ cell populations in gut and skin.

Published in:

Nature Immunology, 2009, v. 10, n. 1, p. 75, doi. 10.1038/ni.1681

By:

Luci, Carmelo;
Reynders, Ana;
Ivanov, Ivaylo I;
Cognet, Celine;
Chiche, Laurent;
Chasson, Lionel;
Hardwigsen, Jean;
Anguiano, Esperanza;
Banchereau, Jacques;
Chaussabel, Damien;
Dalod, Marc;
Littman, Dan R;
Vivier, Eric;
Tomasello, Elena

Publication type:

Article

ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage.

Published in:

Nature Immunology, 2008, v. 9, n. 10, p. 1131, doi. 10.1038/ni.1652

By:

Egawa, Takeshi;
Littman, Dan R

Publication type:

Article

Restoration of lymphoid organ integrity through the interaction of lymphoid tissue–inducer cells with stroma of the T cell zone.

Published in:

Nature Immunology, 2008, v. 9, n. 6, p. 667, doi. 10.1038/ni.1605

By:

Scandella, Elke;
Bolinger, Beatrice;
Lattmann, Evelyn;
Miller, Simone;
Favre, Stéphanie;
Littman, Dan R;
Finke, Daniela;
Luther, Sanjiv A;
Junt, Tobias;
Ludewig, Burkhard

Publication type:

Article

The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt.

Published in:

Nature Immunology, 2008, v. 9, n. 6, p. 641, doi. 10.1038/ni.1610

By:

Manel, Nicolas;
Unutmaz, Derya;
Littman, Dan R

Publication type:

Article

IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways.

Published in:

Nature Immunology, 2007, v. 8, n. 9, p. 967, doi. 10.1038/ni1488

By:

Zhou, Liang;
Ivanov, Ivaylo I;
Spolski, Rosanne;
Min, Roy;
Shenderov, Kevin;
Egawa, Takeshi;
Levy, David E;
Leonard, Warren J;
Littman, Dan R

Publication type:

Article

An essential function for the nuclear receptor ROR?t in the generation of fetal lymphoid tissue inducer cells.

Published in:

Nature Immunology, 2004, v. 5, n. 1, p. 64, doi. 10.1038/ni1022

By:

Eberl, Gérard;
Marmon, Shana;
Sunshine, Mary-Jean;
Rennert, Paul D.;
Yongwon Choi;
Littman, Dan R.

Publication type:

Article

Regulation of the TCRa repertoire by the survival window of CD4+CD8+ thymocytes.

Published in:

Nature Immunology, 2002, v. 3, n. 5, p. 469, doi. 10.1038/ni791

By:

Guo, Jian;
Hawwari, Abbas;
Li, Hong;
Sun, Zuoming;
Mahanta, Sanjeev K.;
Littman, Dan R.;
Krangel, Michael S.;
He, You-Wen

Publication type:

Article

Inactivation of Notch1 in immature thymocytes does not perturb CD4 or CD8 T cell development.

Published in:

Nature Immunology, 2001, v. 2, n. 3, p. 235, doi. 10.1038/85294

By:

Wolfer, Anita;
Bakker, Talitha;
Wilson, Anne;
Nicolas, Michael;
Ioannidis, Vassilios;
Littman, Dan R.;
Wilson, Christopher B.;
Held, Werner;
MacDonald, H. Robson;
Radtke, Freddy

Publication type:

Article

Review: Microbiome in Inflammatory Arthritis and Human Rheumatic Diseases.

Published in:

Arthritis & Rheumatology, 2016, v. 68, n. 1, p. 35, doi. 10.1002/art.39259

By:

Scher, Jose U.;
Littman, Dan R.;
Abramson, Steven B.

Publication type:

Article

Decreased Bacterial Diversity Characterizes the Altered Gut Microbiota in Patients With Psoriatic Arthritis, Resembling Dysbiosis in Inflammatory Bowel Disease.

Published in:

Arthritis & Rheumatology, 2015, v. 67, n. 1, p. 128, doi. 10.1002/art.38892

By:

Scher, Jose U.;
Ubeda, Carles;
Artacho, Alejandro;
Attur, Mukundan;
Isaac, Sandrine;
Reddy, Soumya M.;
Marmon, Shoshana;
Neimann, Andrea;
Brusca, Samuel;
Patel, Tejas;
Manasson, Julia;
Pamer, Eric G.;
Littman, Dan R.;
Abramson, Steven B.

Publication type:

Article

Nramp1 expression by dendritic cells modulates inflammatory responses during Salmonella Typhimurium infection.

Published in:

Cellular Microbiology, 2008, v. 10, n. 8, p. 1646, doi. 10.1111/j.1462-5822.2008.01155.x

By:

Valdez, Yanet;
Diehl, Gretchen E.;
Vallance, Bruce A.;
Grassl, Guntram A.;
Guttman, Julian A.;
Brown, Nat F.;
Rosenberger, Carrie M.;
Littman, Dan R.;
Gros, Philippe;
Finlay, B. Brett

Publication type:

Article

CD4 expression in effector T cells depends on DNA demethylation over a developmentally established stimulus-responsive element.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28914-4

By:

Teghanemt, Athmane;
Pulipati, Priyanjali;
Misel-Wuchter, Kara;
Day, Kenneth;
Yorek, Matthew S.;
Yi, Ren;
Keen, Henry L.;
Au, Christy;
Maretzky, Thorsten;
Gurung, Prajwal;
Littman, Dan R.;
Issuree, Priya D.

Publication type:

Article

Mice Transgenic for CD4-Specific Human CD4, CCR5 and Cyclin T1 Expression: A New Model for Investigating HIV-1 Transmission and Treatment Efficacy

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063537

By:

Seay, Kieran;
Qi, Xiaohua;
Zheng, Jian Hua;
Zhang, Cong;
Chen, Ken;
Dutta, Monica;
Deneroff, Kathryn;
Ochsenbauer, Christina;
Kappes, John C.;
Littman, Dan R.;
Goldstein, Harris

Publication type:

Article

Impact of the TCR Signal on Regulatory T Cell Homeostasis, Function, and Trafficking.

Published in:

PLoS ONE, 2009, v. 4, n. 8, p. 1, doi. 10.1371/journal.pone.0006580

By:

Joong Kyu Kim;
Klinger, Mark;
Benjamin, Jonathan;
Yuanyuan Xiao;
Erle, David J.;
Littman, Dan R.;
Killeen, Nigel

Publication type:

Article

Relief of Preintegration Inhibition and Characterization of Additional Blocks for HIV Replication in Primary Mouse T Cells.

Published in:

PLoS ONE, 2008, v. 3, n. 4, p. 1, doi. 10.1371/journal.pone.0002035

By:

Jing-xin Zhang;
Diehl, Gretchen E.;
Littman, Dan R.

Publication type:

Article

Lineage Diversion of T Cell Receptor Transgenic Thymocytes Revealed by Lineage Fate Mapping.

Published in:

PLoS ONE, 2008, v. 3, n. 1, p. 1, doi. 10.1371/journal.pone.0001512

By:

Egawa, Takeshi;
Kreslavsky, Taras;
Littman, Dan R.;
von Boehmer, Harald

Publication type:

Article

The Chemokine Stromal Cell-Derived Factor-1 Promotes the Survival of Embryonic Retinal Ganglion Cells.

Published in:

Journal of Neuroscience, 2003, v. 23, n. 11, p. 4601, doi. 10.1523/JNEUROSCI.23-11-04601.2003

By:

Chalasani, Sreekanth H.;
Baribaud, Frederic;
Coughlan, Christine M.;
Sunshine, Mary J.;
Lee, Virginia M. Y.;
Doms, Robert W.;
Littman, Dan R.;
Raper, Jonathan A.

Publication type:

Article

Deciphering the regulatory landscape of fetal and adult γδ T‐cell development at single‐cell resolution.

Published in:

EMBO Journal, 2020, v. 39, n. 13, p. 1, doi. 10.15252/embj.2019104159

By:

Sagar;
Pokrovskii, Maria;
Herman, Josip S;
Naik, Shruti;
Sock, Elisabeth;
Zeis, Patrice;
Lausch, Ute;
Wegner, Michael;
Tanriver, Yakup;
Littman, Dan R;
Grün, Dominic

Publication type:

Article

The neuronal chemokine CX3CL1/fractalkine selectively recruits NK cells that modify experimental autoimmune encephalomyelitis within the central nervous system.

Published in:

FASEB Journal, 2006, v. 20, n. 7, p. 896, doi. 10.1096/fj.05-5465com

By:

DeRen Huang;
Fu-Dong Shi;
Jung, Steffen;
Pien, Gary C.;
Jintang Wang;
Salazar-Mather, Thais P.;
He, Toby T.;
Weaver, Jennifer T.;
Ljunggren, Hans-Gustaf;
Biron, Christine A.;
Littman, Dan R.;
Ransohoff, Richard M.

Publication type:

Article

Lung eosinophils elicited during allergic and acute aspergillosis express RORɣt and IL-23R but do not require IL-23 for IL-17 production.

Published in:

PLoS Pathogens, 2021, v. 17, n. 8, p. 1, doi. 10.1371/journal.ppat.1009891

By:

Yadav, Bhawna;
Specht, Charles A.;
Lee, Chrono K.;
Pokrovskii, Maria;
Huh, Jun R.;
Littman, Dan R.;
Levitz, Stuart M.

Publication type:

Article

Small molecule inhibitors of RORγt: Targeting Th17 cells and other applications.

Published in:

European Journal of Immunology, 2012, v. 42, n. 9, p. 2232, doi. 10.1002/eji.201242740

By:

Huh, Jun R.;
Littman, Dan R.

Publication type:

Article

Provocateurs of autoimmunity within the gut microbiota.

Published in:

Science Translational Medicine, 2022, v. 14, n. 668, p. 1, doi. 10.1126/scitranslmed.add3901

By:

Upadhyay, Rabi;
Littman, Dan R.

Publication type:

Article

PKC-ϑ knockout mice are protected from fat-induced insulin resistance.

Published in:

Journal of Clinical Investigation, 2004, v. 114, n. 6, p. 823, doi. 10.1172/JCI200422230

By:

Kim, Jason K.;
Fillmore, Jonathan J.;
Sunshine, Mary Jean;
Albrecht, Bjoern;
Higashimori, Takamasa;
Kim, Dong-wook;
Liu, Zhen-xiang;
Soos, Timothy J.;
Cline, Gary W.;
O'brien, William R.;
Littman, Dan R.;
Shulman, Gerald I.

Publication type:

Article

PKC-theta knockout mice are protected from fat-induced insulin resistance.

Published in:

2004

By:

Kim, Jason K;
Fillmore, Jonathan J;
Sunshine, Mary Jean;
Albrecht, Bjoern;
Higashimori, Takamasa;
Kim, Dong-Wook;
Liu, Zhen-Xiang;
Soos, Timothy J;
Cline, Gary W;
O'Brien, William R;
Littman, Dan R;
Shulman, Gerald I

Publication type:

journal article

Cell-cell adhesion mediated by CD8 and MHC class I molecules.

Published in:

Nature, 1988, v. 336, n. 6194, p. 79, doi. 10.1038/336079a0

By:

Norment, Anne M.;
Salter, Russell D.;
Parham, Peter;
Engelhard, Victor H.;
Littman, Dan R.

Publication type:

Article

The envelope glycoprotein of the human immunodeficiency virus binds to the immunoglobulin-like domain of CD4.

Published in:

Nature, 1988, v. 334, n. 6178, p. 159, doi. 10.1038/334159a0

By:

Landau, Nathaniel R.;
Warton, Maria;
Littman, Dan R.

Publication type:

Article

Internalization of the human immunodeficiency virus does not require the cytoplasmic domain of CD4.

Published in:

Nature, 1988, v. 334, n. 6178, p. 162, doi. 10.1038/334162a0

By:

Bedinger, Patricia;
Moriarty, Ann;
von Borstel, Robert C.;
Donovan, Nancy J.;
Steimer, Kathelyn S.;
Littman, Dan R.

Publication type:

Article

Identification and sequence of a fourth human T cell antigen receptor chain.

Published in:

Nature, 1987, v. 330, n. 6148, p. 569, doi. 10.1038/330569a0

By:

Loh, Elwyn Y.;
Lanier, Lewis L.;
Turck, Christoph W.;
Littman, Dan R.;
Davis, Mark M.;
Chien, Yueh-Hsiu;
Weiss, Arthur

Publication type:

Article

Disrupting Hepatocyte Cyp51 from Cholesterol Synthesis Leads to Progressive Liver Injury in the Developing Mouse and Decreases RORC Signalling.

Published in:

Scientific Reports, 2017, p. 40775, doi. 10.1038/srep40775

By:

Urlep, Žiga;
Lorbek, Gregor;
Perše, Martina;
Jeruc, Jera;
Juvan, Peter;
Matz-Soja, Madlen;
Gebhardt, Rolf;
Björkhem, Ingemar;
Hall, Jason A.;
Bonneau, Richard;
Littman, Dan R.;
Rozman, Damjana

Publication type:

Article

Drosha regulates neurogenesis by controlling Neurogenin 2 expression independent of microRNAs.

Published in:

Nature Neuroscience, 2012, v. 15, n. 7, p. 962, doi. 10.1038/nn.3139

By:

Knuckles, Philip;
Vogt, Miriam A;
Lugert, Sebastian;
Milo, Marta;
Chong, Mark M W;
Hautbergue, Guillaume M;
Wilson, Stuart A;
Littman, Dan R;
Taylor, Verdon

Publication type:

Article

Control of microglial neurotoxicity by the fractalkine receptor.

Published in:

Nature Neuroscience, 2006, v. 9, n. 7, p. 917, doi. 10.1038/nn1715

By:

Cardona, Astrid E.;
Pioro, Erik P.;
Sasse, Margaret E.;
Kostenko, Volodymyr;
Cardona, Sandra M.;
Dijkstra, Ineke M.;
Huang, DeRen;
Kidd, Grahame;
Dombrowski, Stephen;
Dutta, RanJan;
Lee, Jar-Chi;
Cook, Donald N.;
Jung, Steffen;
Lira, Sergio A.;
Littman, Dan R.;
Ransohoff, Richard M.

Publication type:

Article

ATP mediates rapid microglial response to local brain injury in vivo.

Published in:

Nature Neuroscience, 2005, v. 8, n. 6, p. 752, doi. 10.1038/nn1472

By:

Davalos, Dimitrios;
Grutzendler, Jaime;
Guang Yang;
Kim, Jiyun V.;
Yi Zuo;
Jung, Steffen;
Littman, Dan R.;
Dustin, Michael L.;
Gan, Wen-Biao

Publication type:

Article

A Huntington's disease CAG expansion at the murine Hdh locus is unstable and associated with behavioural abnormalities in mice.

Published in:

Human Molecular Genetics, 1999, v. 8, n. 5, p. 763, doi. 10.1093/hmg/8.5.763

By:

Shelbourne, Peggy F.;
Killeen, Nigel;
Hevner, Robert F.;
Johnston, Heather M.;
Tecott, Laurence;
Lewandoski, Mark;
Ennis, Margaret;
Ramirez, Lucia;
Li, Zhen;
Iannicola, Carlo;
Littman, Dan R.;
Myers, Richard M.

Publication type:

Article

Stage-specific epigenetic regulation of CD4 expression by coordinated enhancer elements during T cell development.

Published in:

Nature Communications, 2018, p. 1, doi. 10.1038/s41467-018-05834-w

By:

Issuree, Priya D.;
Day, Kenneth;
Au, Christy;
Ramya Raviram;
Zappile, Paul;
Skok, Jane A.;
Hai-Hui Xue;
Myers, Richard M.;
Littman, Dan R.

Publication type:

Article

Intravascular Immune Surveillance by CXCR6+ NKT Cells Patrolling Liver Sinusoids.

Published in:

PLoS Biology, 2005, v. 3, n. 4, p. 1, doi. 10.1371/journal.pbio.0030113

By:

Geissmann, Frederic;
Cameron, Thomas O;
Sidobre, Stephane;
Manlongat, Natasha;
Kronenberg, Mitchell;
Briskin, Michael J;
Dustin, Michael L;
Littman, Dan R

Publication type:

Article

Intravascular Immune Surveillance by CXCR6+ NKT Cells Patrolling Liver Sinusoids.

Published in:

PLoS Biology, 2005, v. 3, n. 4, p. 650, doi. 10.1371/journal.pbio.0030113

By:

Geissmann, Frederic;
Cameron, Thomas O.;
Sidobre, Stephane;
Manlongat, Natasha;
Kronenberg, Mitchell;
Briskin, Michael J.;
Dustin, Michael L.;
Littman, Dan R.

Publication type:

Article

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development.

Published in:

Nature, 1998, v. 393, n. 6685, p. 595, doi. 10.1038/31269

By:

Zou, Yong-Rui;
Kottmann, Andreas H.;
Kuroda, Masahiko;
Taniuchi, Ichiro;
Littman, Dan R.

Publication type:

Article

Natural resistance to HIV?

Published in:

Nature, 1996, v. 382, n. 6593, p. 668, doi. 10.1038/382668a0

By:

Hill, C. Mark;
Littman, Dan R.

Publication type:

Article

Helper T-cell development in the absence of CD4-p56lck association.

Published in:

Nature, 1993, v. 364, n. 6439, p. 729, doi. 10.1038/364729a0

By:

Killeen, Nigel;
Littman, Dan R.

Publication type:

Article

Sparse and Compositionally Robust Inference of Microbial Ecological Networks.

Published in:

PLoS Computational Biology, 2015, v. 11, n. 5, p. 1, doi. 10.1371/journal.pcbi.1004226

By:

Kurtz, Zachary D.;
Müller, Christian L.;
Miraldi, Emily R.;
Littman, Dan R.;
Blaser, Martin J.;
Bonneau, Richard A.

Publication type:

Article

The role of the nuclear hormone receptor RORγt in the development of lymph nodes and Peyer's patches.

Published in:

Immunological Reviews, 2003, v. 195, n. 1, p. 81, doi. 10.1034/j.1600-065X.2003.00074.x

By:

Eberl, Gerard;
Littman, Dan R.

Publication type:

Article