Works by Littlechild, Jennifer A.

Results: 46

Anion Binding Tripodal Receptors as Structural Models for the Active Site of Vanadium Haloperoxidases and Acid Phosphatases.

Published in:

Supramolecular Chemistry, 2006, v. 18, n. 1, p. 55, doi. 10.1080/10610270500368840

By:

Tapper, Sophia;
Littlechild, Jennifer A.;
Molard, Yann;
Prokes, Ivan;
Tucker, James H. R.

Publication type:

Article

Thermophilic enzymes and their applications in biocatalysis: a robust aldo-keto reductase.

Published in:

Environmental Technology, 2010, v. 31, n. 10, p. 1159, doi. 10.1080/09593330.2010.490857

By:

Willies, Simon;
Isupov, Misha;
Littlechild, Jennifer

Publication type:

Article

The crystal structure of Arabidopsis BON1 provides insights into the copine protein family.

Published in:

Plant Journal, 2020, v. 103, n. 3, p. 1215, doi. 10.1111/tpj.14797

By:

Wang, Qianchao;
Jiang, Meiqin;
Isupov, Michail N.;
Chen, Yayu;
Littlechild, Jennifer A.;
Sun, Lifang;
Wu, Xiuling;
Wang, Qin;
Yang, Wendi;
Chen, Lifei;
Li, Qi;
Wu, Yunkun

Publication type:

Article

Structural and functional comparisons between vanadium haloperoxidase and acid phosphatase enzymes.

Published in:

Journal of Molecular Recognition, 2002, v. 15, n. 5, p. 291, doi. 10.1002/jmr.590

By:

Littlechild, Jennifer;
Garcia-Rodriguez, Esther;
Dalby, Andrew;
Isupov, Misha

Publication type:

Article

Cloning and expression of cytosolic phosphoglycerate kinase from pea (Pisum sativum L.).

Published in:

Journal of Experimental Botany, 2004, v. 55, n. 398, p. 955, doi. 10.1093/jxb/erh096

By:

Brice, David C.;
Bryant, John A.;
Dambrauskas, Gerardas;
Drury, Suzanne C.;
Littlechild, Jennifer A.

Publication type:

Article

Biochemical and structural studies of a l-haloacid dehalogenase from the thermophilic archaeon Sulfolobus tokodaii.

Published in:

Extremophiles, 2009, v. 13, n. 1, p. 179, doi. 10.1007/s00792-008-0208-0

By:

Rye, Carrie A.;
Isupov, Michail N.;
Lebedev, Andrey A.;
Littlechild, Jennifer A.

Publication type:

Article

A thermostable L-aminoacylase from Thermococcus litoralis: cloning, overexpression, characterization, and applications in biotransformations.

Published in:

Extremophiles, 2002, v. 6, n. 2, p. 111, doi. 10.1007/s007920100230

By:

Toogood, Helen S.;
Hollingsworth, Edward J.;
Brown, Rob C.;
Taylor, Ian N.;
Taylor, Stephen J.;
McCague, Ray;
Littlechild, Jennifer A.

Publication type:

Article

Stabilization of a Lipolytic Enzyme for Commercial Application.

Published in:

Catalysts (2073-4344), 2017, v. 7, n. 3, p. 91, doi. 10.3390/catal7030091

By:

De Rose, Simone Antonio;
Novak, Halina;
Dowd, Andrew;
Singh, Sukriti;
Lang, Dietmar Andreas;
Littlechild, Jennifer

Publication type:

Article

A 'Split-Gene' Transketolase From the Hyper-Thermophilic Bacterium Carboxydothermus hydrogenoformans : Structure and Biochemical Characterization.

Published in:

Frontiers in Microbiology, 2020, v. 11, p. N.PAG, doi. 10.3389/fmicb.2020.592353

By:

James, Paul;
Isupov, Michail N.;
De Rose, Simone Antonio;
Sayer, Christopher;
Cole, Isobel S.;
Littlechild, Jennifer A.

Publication type:

Article

Biochemical and structural characterisation of a haloalkane dehalogenase from a marine Rhodobacteraceae.

Published in:

FEBS Letters, 2014, v. 588, n. 9, p. 1616, doi. 10.1016/j.febslet.2014.02.056

By:

Novak, Halina R.;
Sayer, Christopher;
Isupov, Michail N.;
Gotz, Dorothee;
Spragg, Andrew Mearns;
Littlechild, Jennifer A.

Publication type:

Article

The structure of a thermally stable 3-phosphoglycerate kinase and a comparison with its mesophilic equivalent.

Published in:

Proteins, 1993, v. 15, n. 3, p. 283, doi. 10.1002/prot.340150306

By:

Davies, Gideon J.;
Gamblin, Steven J.;
Littlechild, Jennifer A.;
Watson, Herman C.

Publication type:

Article

Marine Rhodobacteraceae l-haloacid dehalogenase contains a novel His/ Glu dyad that could activate the catalytic water.

Published in:

FEBS Journal, 2013, v. 280, n. 7, p. 1664, doi. 10.1111/febs.12177

By:

Novak, Halina R.;
Sayer, Christopher;
Isupov, Michail N.;
Paszkiewicz, Konrad;
Gotz, Dorothee;
Mearns Spragg, Andrew;
Littlechild, Jennifer A.

Publication type:

Article

Biosensors and Diagnostics for Fungal Detection.

Published in:

Journal of Fungi, 2020, v. 6, n. 4, p. 1, doi. 10.3390/jof6040349

By:

Hussain, Khalil K.;
Malavia, Dhara;
Johnson, Elizabeth M.;
Littlechild, Jennifer;
Winlove, C. Peter;
Vollmer, Frank;
Gow, Neil A. R.

Publication type:

Article

Immobilisation of the Thermostable l -aminoacylase from Thermococcus litoralis to Generate a Reusable Industrial Biocatalyst.

Published in:

Biocatalysis & Biotransformation, 2002, v. 20, n. 4, p. 241, doi. 10.1080/10242420290029472

By:

Toogood, Helen S.;
Taylor, Ian N.;
Brown, Rob C.;
Taylor, Stephen J.C.;
Mccague, Ray;
Littlechild, Jennifer A.

Publication type:

Article

Discovery and Characterization of a Thermostable and Highly Halotolerant GH5 Cellulase from an Icelandic Hot Spring Isolate.

Published in:

PLoS ONE, 2016, v. 11, n. 1, p. 1, doi. 10.1371/journal.pone.0146454

By:

Zarafeta, Dimitra;
Kissas, Dimitrios;
Sayer, Christopher;
Gudbergsdottir, Sóley R.;
Ladoukakis, Efthymios;
Isupov, Michail N.;
Chatziioannou, Aristotelis;
Peng, Xu;
Littlechild, Jennifer A.;
Skretas, Georgios;
Kolisis, Fragiskos N.

Publication type:

Article

Structural characterization of a novel cyclic 2,3-diphosphoglycerate synthetase involved in extremolyte production in the archaeon Methanothermus fervidus.

Published in:

Frontiers in Microbiology, 2023, p. 1, doi. 10.3389/fmicb.2023.1267570

By:

De Rose, Simone A.;
Isupov, Michail N.;
Worthy, Harley L.;
Stracke, Christina;
Harmer, Nicholas J.;
Siebers, Bettina;
Littlechild, Jennifer A.

Publication type:

Article

Enantioselectivity of recombinant Rhizomucor miehei lipase in the ring opening of oxazolin-5(4H)-ones.

Published in:

Protein Engineering, 2001, v. 14, n. 4, p. 269, doi. 10.1093/protein/14.4.269

By:

Turner, Nigel A.;
Gaskin, Duncan J. H.;
Yagnik, Asutosh T.;
Littlechild, Jennifer A.;
Vulfson, Evgeny N.

Publication type:

Article

Modification of halogen specificity of a vanadium-dependent bromoperoxidase.

Published in:

Protein Science: A Publication of the Protein Society, 2004, v. 13, n. 6, p. 1566, doi. 10.1110/ps.03496004

By:

Ohshiro, Takashi;
Littlechild, Jennifer;
Garcia-Rodriguez, Esther;
Isupov, Michail N.;
Iida, Yasuaki;
Kobayashi, Takushi;
Izumi, Yoshikazu

Publication type:

Article

The Structure of a Novel Thermophilic Esterase from the Planctomycetes Species, Thermogutta terrifontis Reveals an Open Active Site Due to a Minimal 'Cap' Domain.

Published in:

Frontiers in Microbiology, 2015, v. 6, p. 1, doi. 10.3389/fmicb.2015.01294

By:

Sayer, Christopher;
Szabo, Zalan;
Isupov, Michail N.;
Ingham, Colin;
Littlechild, Jennifer A.;
Shawn Chen;
Kovacic, Filip

Publication type:

Article

Functional and structural characterisation of a viral cytochrome b5.

Published in:

FEBS Letters, 2013, v. 587, n. 22, p. 3633, doi. 10.1016/j.febslet.2013.09.035

By:

Reid, Emma L.;
Weynberg, Karen D.;
Love, John;
Isupov, Michail N.;
Littlechild, Jennifer A.;
Wilson, William H.;
Kelly, Steven L.;
Lamb, David C.;
Allen, Michael J.

Publication type:

Article

Crystal structure of human muscle aldolase complexed with fructose 1,6-bisphosphate: Mechanistic implications.

Published in:

Protein Science: A Publication of the Protein Society, 1999, v. 8, n. 2, p. 291

By:

DALBY, ANDREW;
DAUTER, ZBIGNIEV;
LITTLECHILD, JENNIFER A.

Publication type:

Article

X-ray structure of Fasciola hepatica Sigma class glutathione transferase 1 reveals a disulfide bond to support stability in gastro-intestinal environment.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-37531-5

By:

Line, Kirsty;
Isupov, Michail N.;
LaCourse, E. James;
Cutress, David J.;
Morphew, Russell M.;
Brophy, Peter M.;
Littlechild, Jennifer A.

Publication type:

Article

Biocatalysis as Key to Sustainable Industrial Chemistry.

Published in:

ChemSusChem, 2022, v. 15, n. 9, p. 1, doi. 10.1002/cssc.202102709

By:

Alcántara, Andrés R.;
Domínguez de María, Pablo;
Littlechild, Jennifer A.;
Schürmann, Martin;
Sheldon, Roger A.;
Wohlgemuth, Roland

Publication type:

Article

Front Cover: Biocatalysis as Key to Sustainable Industrial Chemistry (ChemSusChem 9/2022).

Published in:

ChemSusChem, 2022, v. 15, n. 9, p. 1, doi. 10.1002/cssc.202200707

By:

Alcántara, Andrés R.;
Domínguez de María, Pablo;
Littlechild, Jennifer A.;
Schürmann, Martin;
Sheldon, Roger A.;
Wohlgemuth, Roland

Publication type:

Article

Preface to Special Issue on Biocatalysis as Key to Sustainable Industrial Chemistry.

Published in:

ChemSusChem, 2022, v. 15, n. 9, p. 1, doi. 10.1002/cssc.202200640

By:

Alcántara, Andrés R.;
Domínguez de María, Pablo;
Littlechild, Jennifer A.;
Schürmann, Martin;
Sheldon, Roger A.;
Wohlgemuth, Roland

Publication type:

Article

Biocatalysis as Key to Sustainable Industrial Chemistry.

Published in:

ChemSusChem, 2022, v. 15, n. 9, p. 1, doi. 10.1002/cssc.202102709

By:

Alcántara, Andrés R.;
Domínguez de María, Pablo;
Littlechild, Jennifer A.;
Schürmann, Martin;
Sheldon, Roger A.;
Wohlgemuth, Roland

Publication type:

Article

Amino acid properties may be useful in predicting clinical outcome in patients with Kir6.2 neonatal diabetes.

Published in:

European Journal of Endocrinology, 2012, v. 167, n. 3, p. 417, doi. 10.1530/EJE-12-0227

By:

Fraser, Clementine S.;
Rubio-Cabezas, Oscar;
Littlechild, Jennifer A.;
Ellard, Sian;
Hattersley, Andrew T.;
Flanagan, Sarah E.

Publication type:

Article

Structural characterization of geranylgeranyl pyrophosphate synthase GACE1337 from the hyperthermophilic archaeon Geoglobus acetivorans.

Published in:

Extremophiles, 2018, v. 22, n. 6, p. 877, doi. 10.1007/s00792-018-1044-5

By:

Petrova, Tatiana E.;
Boyko, Konstantin M.;
Nikolaeva, Alena Yu.;
Stekhanova, Tatiana N.;
Gruzdev, Eugeny V.;
Mardanov, Andrey V.;
Stroilov, Viktor S.;
Littlechild, Jennifer A.;
Popov, Vladimir O.;
Bezsudnova, Ekaterina Yu.

Publication type:

Article

Diversity of bacteria and archaea from two shallow marine hydrothermal vents from Vulcano Island.

Published in:

Extremophiles, 2017, v. 21, n. 4, p. 733, doi. 10.1007/s00792-017-0938-y

By:

Antranikian, Garabed;
Suleiman, Marcel;
Schäfers, Christian;
Adams, Michael;
Bartolucci, Simonetta;
Blamey, Jenny;
Birkeland, Nils-Kåre;
Bonch-Osmolovskaya, Elizaveta;
Costa, Milton;
Cowan, Don;
Danson, Michael;
Forterre, Patrick;
Kelly, Robert;
Ishino, Yoshizumi;
Littlechild, Jennifer;
Moracci, Marco;
Noll, Kenneth;
Oshima, Tairo;
Robb, Frank;
Rossi, Mosè

Publication type:

Article

Establishment of an efficient one-step enzymatic synthesis of cyclic-2,3-diphosphoglycerate.

Published in:

Frontiers in Microbiology, 2025, p. 1, doi. 10.3389/fmicb.2025.1601972

By:

Stracke, Christina;
Meyer, Benjamin H.;
De Rose, Simone A.;
Ferrandi, Erica Elisa;
Kublanov, Ilya V.;
Isupov, Michail N.;
Harmer, Nicholas J.;
Monti, Daniela;
Littlechild, Jennifer;
Müller, Felix;
Snoep, Jacky L.;
Bräsen, Christopher;
Siebers, Bettina

Publication type:

Article

Tps1 regulates the pentose phosphate pathway, nitrogen metabolism and fungal virulence.

Published in:

EMBO Journal, 2007, v. 26, n. 15, p. 3673, doi. 10.1038/sj.emboj.7601795

By:

Wilson, Richard A.;
Jenkinson, Joanna M.;
Gibson, Robert P.;
Littlechild, Jennifer A.;
Zheng-Yi Wang;
Talbot, Nicholas J.

Publication type:

Article

The oxygenating constituent of 3,6‐diketocamphane monooxygenase from the CAM plasmid of <italic>Pseudomonas putida</italic>: the first crystal structure of a type II Baeyer–Villiger monooxygenase. Corrigendum.

Published in:

2018

By:

Isupov, Michail N.;
Schröder, Ewald;
Gibson, Robert P.;
Beecher, Jean;
Donadio, Giuliana;
Saneei, Vahid;
Dcunha, Stephlina A.;
McGhie, Emma J.;
Sayer, Christopher;
Davenport, Colin F.;
Lau, Peter C. K.;
Hasegawa, Yoshie;
Iwaki, Hiroaki;
Kadow, Maria;
Balke, Kathleen;
Bornscheuer, Uwe T.;
Bourenkov, Gleb;
Littlechild, Jennifer A.

Publication type:

Correction Notice

A microreactor for the study of biotransformations by a cross-linked γ-lactamase enzyme.

Published in:

Biotechnology Journal, 2009, v. 4, n. 4, p. 510, doi. 10.1002/biot.200800302

By:

Hickey, Anne Marie;
Ngamsom, Bongkot;
Wiles, Charlotte;
Greenway, Gillian M.;
Watts, Paul;
Littlechild, Jennifer A.

Publication type:

Article

Engineering a Seven Enzyme Biotransformation using Mathematical Modelling and Characterized Enzyme Parts.

Published in:

ChemCatChem, 2019, v. 11, n. 15, p. 3474, doi. 10.1002/cctc.201900646

By:

Finnigan, William;
Cutlan, Rhys;
Snajdrova, Radka;
Adams, Joseph P.;
Littlechild, Jennifer A.;
Harmer, Nicholas J.

Publication type:

Article

Characterization of Carboxylic Acid Reductases as Enzymes in the Toolbox for Synthetic Chemistry.

Published in:

ChemCatChem, 2017, v. 9, n. 6, p. 1005, doi. 10.1002/cctc.201601249

By:

Finnigan, William;
Thomas, Adam;
Cromar, Holly;
Gough, Ben;
Snajdrova, Radka;
Adams, Joseph P.;
Littlechild, Jennifer A.;
Harmer, Nicholas J.

Publication type:

Article

The binding of haem and zinc in the 1.9 Å X-ray structure of Escherichia coli bacterioferritin.

Published in:

Journal of Biological Inorganic Chemistry (JBIC), 2009, v. 14, n. 2, p. 201, doi. 10.1007/s00775-008-0438-8

By:

Willies, Simon C.;
Isupov, Michail N.;
Garman, Elspeth F.;
Littlechild, Jennifer A.

Publication type:

Article

Enhancing effect of calcium and vanadium ions on thermal stability of bromoperoxidase from Corallina pilulifera.

Published in:

Journal of Biological Inorganic Chemistry (JBIC), 2005, v. 10, n. 3, p. 275, doi. 10.1007/s00775-005-0639-3

By:

Garcia-Rodriguez, Esther;
Ohshiro, Takashi;
Aibara, Toshiaki;
Izumi, Yoshikazu;
Littlechild, Jennifer

Publication type:

Article

High-Level Heterologous Expression of Endo-1,4-β-Xylanase from Penicillium citrinum in Pichia pastoris X-33 Directed through Codon Optimization and Optimized Expression.

Published in:

Molecules, 2019, v. 24, n. 19, p. 3515, doi. 10.3390/molecules24193515

By:

Ouephanit, Chanika;
Boonvitthya, Nassapat;
Bozonnet, Sophie;
Chulalaksananukul, Warawut;
Littlechild, Jennifer

Publication type:

Article

Substrate specificity of branched chain amino acid aminotransferases: The substitution of glycine to serine in the active site determines the substrate specificity for α-ketoglutarate.

Published in:

Frontiers in Catalysis, 2022, p. 1, doi. 10.3389/fctls.2022.867811

By:

Sutter, Jan-Moritz;
Mitchell, Daniel E.;
Schmidt, Marcel;
Isupov, Michail N.;
Littlechild, Jennifer A.;
Schönheit, Peter

Publication type:

Article

Characterisation of an l-Haloacid Dehalogenase from the Marine Psychrophile Psychromonas ingrahamii with Potential Industrial Application.

Published in:

Marine Biotechnology, 2013, v. 15, n. 6, p. 695, doi. 10.1007/s10126-013-9522-3

By:

Novak, Halina;
Sayer, Christopher;
Panning, Jana;
Littlechild, Jennifer

Publication type:

Article

Structural and biochemical characterisation of Archaeoglobus fulgidus esterase reveals a bound CoA molecule in the vicinity of the active site.

Published in:

Scientific Reports, 2016, p. 25542, doi. 10.1038/srep25542

By:

Sayer, Christopher;
Finnigan, William;
Isupov, Michail N.;
Levisson, Mark;
Kengen, Servé W. M.;
van der Oost, John;
Harmer, Nicholas J.;
Littlechild, Jennifer A.

Publication type:

Article

Archaeal Enzymes and Applications in Industrial Biocatalysts.

Published in:

Archaea, 2015, v. 2015, p. 1, doi. 10.1155/2015/147671

By:

Littlechild, Jennifer A.

Publication type:

Article

Structural basis for the Target DNA recognition and binding by the MYB domain of phosphate starvation response 1.

Published in:

FEBS Journal, 2019, v. 286, n. 14, p. 2809, doi. 10.1111/febs.14846

By:

Jiang, Meiqin;
Sun, Lifang;
Isupov, Michail N.;
Littlechild, Jennifer A.;
Wu, Xiuling;
Wang, Qianchao;
Wang, Qin;
Yang, Wendi;
Wu, Yunkun

Publication type:

Article

Structural studies of a thermophilic esterase from a new Planctomycetes species, Thermogutta terrifontis.

Published in:

FEBS Journal, 2015, v. 282, n. 15, p. 2846, doi. 10.1111/febs.13326

By:

Sayer, Christopher;
Isupov, Michail N.;
Bonch‐Osmolovskaya, Elizaveta;
Littlechild, Jennifer A.

Publication type:

Article

Discovery and characterization of thermophilic limonene-1,2-epoxide hydrolases from hot spring metagenomic libraries.

Published in:

FEBS Journal, 2015, v. 282, n. 15, p. 2879, doi. 10.1111/febs.13328

By:

Ferrandi, Erica Elisa;
Sayer, Christopher;
Isupov, Michail N.;
Annovazzi, Celeste;
Marchesi, Carlotta;
Iacobone, Gianluca;
Peng, Xu;
Bonch‐Osmolovskaya, Elizaveta;
Wohlgemuth, Roland;
Littlechild, Jennifer A.;
Monti, Daniela

Publication type:

Article

The substrate specificity, enantioselectivity and structure of the ( R)-selective amine : pyruvate transaminase from Nectria haematococca.

Published in:

FEBS Journal, 2014, v. 281, n. 9, p. 2240, doi. 10.1111/febs.12778

By:

Sayer, Christopher;
Martinez‐Torres, Ruben J.;
Richter, Nina;
Isupov, Michail N.;
Hailes, Helen C.;
Littlechild, Jennifer A.;
Ward, John M.

Publication type:

Article