Found: 11

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  • Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain.

    Published in:
    PLoS Biology, 2017, v. 15, n. 3, p. 1, doi. 10.1371/journal.pbio.2001882
    By:
    • Lintner, Nathanael G.;
    • McClure, Kim F.;
    • Petersen, Donna;
    • Londregan, Allyn T.;
    • Piotrowski, David W.;
    • Wei, Liuqing;
    • Xiao, Jun;
    • Bolt, Michael;
    • Loria, Paula M.;
    • Maguire, Bruce;
    • Geoghegan, Kieran F.;
    • Huang, Austin;
    • Rolph, Tim;
    • Liras, Spiros;
    • Doudna, Jennifer A.;
    • Dullea, Robert G.;
    • Cate, Jamie H. D.
    Publication type:
    Article

  • Liver-Targeted Small-Molecule Inhibitors of Proprotein Convertase Subtilisin/Kexin Type 9 Synthesis.

    Published in:
    Angewandte Chemie, 2017, v. 129, n. 51, p. 16436, doi. 10.1002/ange.201708744
    By:
    • McClure, Kim F.;
    • Piotrowski, David W.;
    • Petersen, Donna;
    • Wei, Liuqing;
    • Xiao, Jun;
    • Londregan, Allyn T.;
    • Kamlet, Adam S.;
    • Dechert‐Schmitt, Anne‐Marie;
    • Raymer, Brian;
    • Ruggeri, Roger B.;
    • Canterbury, Daniel;
    • Limberakis, Chris;
    • Liras, Spiros;
    • DaSilva‐Jardine, Paul;
    • Dullea, Robert G.;
    • Loria, Paula M.;
    • Reidich, Benjamin;
    • Salatto, Christopher T.;
    • Eng, Heather;
    • Kimoto, Emi
    Publication type:
    Article

  • Liver-Targeted Small-Molecule Inhibitors of Proprotein Convertase Subtilisin/Kexin Type 9 Synthesis.

    Published in:
    Angewandte Chemie International Edition, 2017, v. 56, n. 51, p. 16218, doi. 10.1002/anie.201708744
    By:
    • McClure, Kim F.;
    • Piotrowski, David W.;
    • Petersen, Donna;
    • Wei, Liuqing;
    • Xiao, Jun;
    • Londregan, Allyn T.;
    • Kamlet, Adam S.;
    • Dechert‐Schmitt, Anne‐Marie;
    • Raymer, Brian;
    • Ruggeri, Roger B.;
    • Canterbury, Daniel;
    • Limberakis, Chris;
    • Liras, Spiros;
    • DaSilva‐Jardine, Paul;
    • Dullea, Robert G.;
    • Loria, Paula M.;
    • Reidich, Benjamin;
    • Salatto, Christopher T.;
    • Eng, Heather;
    • Kimoto, Emi
    Publication type:
    Article

  • Improving on Nature: Making a Cyclic Heptapeptide Orally Bioavailable.

    Published in:
    Angewandte Chemie International Edition, 2014, v. 53, n. 45, p. 12059, doi. 10.1002/anie.201405364
    By:
    • Nielsen, Daniel S.;
    • Hoang, Huy N.;
    • Lohman, Rink‐Jan;
    • Hill, Timothy A.;
    • Lucke, Andrew J.;
    • Craik, David J.;
    • Edmonds, David J.;
    • Griffith, David A.;
    • Rotter, Charles J.;
    • Ruggeri, Roger B.;
    • Price, David A.;
    • Liras, Spiros;
    • Fairlie, David P.
    Publication type:
    Article

  • Comparative α-Helicity of Cyclic Pentapeptides in Water.

    Published in:
    Angewandte Chemie International Edition, 2014, v. 53, n. 27, p. 6965, doi. 10.1002/anie.201310245
    By:
    • de Araujo, Aline D.;
    • Hoang, Huy N.;
    • Kok, W. Mei;
    • Diness, Frederik;
    • Gupta, Praveer;
    • Hill, Timothy A.;
    • Driver, Russell W.;
    • Price, David A.;
    • Liras, Spiros;
    • Fairlie, David P.
    Publication type:
    Article

  • The Future of Peptide-based Drugs.

    Published in:
    Chemical Biology & Drug Design, 2013, v. 81, n. 1, p. 136, doi. 10.1111/cbdd.12055
    By:
    • Craik, David J.;
    • Fairlie, David P.;
    • Liras, Spiros;
    • Price, David
    Publication type:
    Article

  • Correction: Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain.

    Published in:
    2018
    By:
    • Lintner, Nathanael G.;
    • McClure, Kim F.;
    • Petersen, Donna;
    • Londregan, Allyn T.;
    • Piotrowski, David W.;
    • Wei, Liuqing;
    • Xiao, Jun;
    • Bolt, Michael;
    • Loria, Paula M.;
    • Maguire, Bruce;
    • Geoghegan, Kieran F.;
    • Huang, Austin;
    • Rolph, Tim;
    • Liras, Spiros;
    • Doudna, Jennifer A.;
    • Dullea, Robert G.;
    • Cate, Jamie H. D.
    Publication type:
    Correction Notice

  • Improving on Nature: Making a Cyclic Heptapeptide Orally Bioavailable.

    Published in:
    Angewandte Chemie, 2014, v. 126, n. 45, p. 12255, doi. 10.1002/ange.201405364
    By:
    • Nielsen, Daniel S.;
    • Hoang, Huy N.;
    • Lohman, Rink ‐ Jan;
    • Hill, Timothy A.;
    • Lucke, Andrew J.;
    • Craik, David J.;
    • Edmonds, David J.;
    • Griffith, David A.;
    • Rotter, Charles J.;
    • Ruggeri, Roger B.;
    • Price, David A.;
    • Liras, Spiros;
    • Fairlie, David P.
    Publication type:
    Article

  • Comparative α-Helicity of Cyclic Pentapeptides in Water.

    Published in:
    Angewandte Chemie, 2014, v. 126, n. 27, p. 7085, doi. 10.1002/ange.201310245
    By:
    • de Araujo, Aline D.;
    • Hoang, Huy N.;
    • Kok, W. Mei;
    • Diness, Frederik;
    • Gupta, Praveer;
    • Hill, Timothy A.;
    • Driver, Russell W.;
    • Price, David A.;
    • Liras, Spiros;
    • Fairlie, David P.
    Publication type:
    Article

  • Chiral Sulfoxide-Induced Single Turn Peptide α-Helicity.

    Published in:
    Scientific Reports, 2016, p. 38573, doi. 10.1038/srep38573
    By:
    • Zhang, Qingzhou;
    • Jiang, Fan;
    • Zhao, Bingchuan;
    • Lin, Huacan;
    • Tian, Yuan;
    • Xie, Mingsheng;
    • Bai, Guoyun;
    • Gilbert, Adam M.;
    • Goetz, Gilles H.;
    • Liras, Spiros;
    • Mathiowetz, Alan A.;
    • Price, David A.;
    • Song, Kun;
    • Tu, Meihua;
    • Wu, Yujie;
    • Wang, Tao;
    • Flanagan, Mark E.;
    • Wu, Yun-Dong;
    • Li, Zigang
    Publication type:
    Article

  • On-resin N-methylation of cyclic peptides for discovery of orally bioavailable scaffolds.

    Published in:
    Nature Chemical Biology, 2011, v. 7, n. 11, p. 810, doi. 10.1038/nchembio.664
    By:
    • White, Tina R;
    • Renzelman, Chad M;
    • Rand, Arthur C;
    • Rezai, Taha;
    • McEwen, Cayla M;
    • Gelev, Vladimir M;
    • Turner, Rushia A;
    • Linington, Roger G;
    • Leung, Siegfried S F;
    • Kalgutkar, Amit S;
    • Bauman, Jonathan N;
    • Zhang, Yizhong;
    • Liras, Spiros;
    • Price, David A;
    • Mathiowetz, Alan M;
    • Jacobson, Matthew P;
    • Lokey, R Scott
    Publication type:
    Article