Found: 28
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Computational investigation of potential dosing schedules for a switch of medication from warfarin to rivaroxaban-an oral, direct Factor Xa inhibitor.
- Published in:
- Frontiers in Physiology, 2014, v. 5, p. 1, doi. 10.3389/fphys.2014.00417
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- Article
Pharmacogenomics of Codeine, Morphine, and Morphine-6-Glucuronide.
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- Molecular Diagnosis & Therapy, 2012, v. 16, n. 1, p. 43, doi. 10.1007/BF03256429
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- Publication type:
- Article
Visual depth encoding in populations of neurons with localized receptive fields.
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- Biological Cybernetics, 2002, v. 87, n. 4, p. 249, doi. 10.1007/s00422-002-0338-x
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- Article
Disparity tuning as simulated by a neural net.
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- Biological Cybernetics, 2000, v. 83, n. 1, p. 61, doi. 10.1007/s004220000146
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- Publication type:
- Article
Pharmacokinetics of rivaroxaban in children using physiologically based and population pharmacokinetic modelling: an EINSTEIN-Jr phase I study.
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- Thrombosis Journal, 2018, v. 16, n. 1, p. N.PAG, doi. 10.1186/s12959-018-0185-1
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- Article
Integrating Cellular Metabolism into a Multiscale Whole-Body Model.
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- PLoS Computational Biology, 2012, v. 8, n. 10, p. 1, doi. 10.1371/journal.pcbi.1002750
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- Publication type:
- Article
Integration of dissolution into physiologically-based pharmacokinetic models III: PK-Sim<sup>®</sup>.
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- Journal of Pharmacy & Pharmacology, 2012, v. 64, n. 7, p. 997, doi. 10.1111/j.2042-7158.2012.01534.x
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- Publication type:
- Article
Predictive Performance of Physiology‐Based Pharmacokinetic Dose Estimates for Pediatric Trials: Evaluation With 10 Bayer Small‐Molecule Compounds in Children.
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- Journal of Clinical Pharmacology, 2021, v. 61, p. S70, doi. 10.1002/jcph.1869
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- Article
Predictive Pediatric Modeling and Simulation Using Ontogeny Information.
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- Journal of Clinical Pharmacology, 2019, v. 59, p. S95, doi. 10.1002/jcph.1497
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- Publication type:
- Article
Predictive Pediatric Modeling and Simulation Using Ontogeny Information.
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- Journal of Clinical Pharmacology, 2019, v. 59, p. S95, doi. 10.1002/jcph.1497
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- Publication type:
- Article
A generic whole body physiologically based pharmacokinetic model for therapeutic proteins in PK-Sim.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2018, v. 45, n. 2, p. 235, doi. 10.1007/s10928-017-9559-4
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- Publication type:
- Article
Meta-analysis of preclinical measures of efficacy in immune checkpoint blockade therapies and comparison to clinical efficacy estimates.
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- Translational Medicine Communications, 2023, v. 8, n. 1, p. 1, doi. 10.1186/s41231-023-00151-x
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- Publication type:
- Article
Multiscale classification of heart failure phenotypes by unsupervised clustering of unstructured electronic medical record data.
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- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-77286-6
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- Publication type:
- Article
Population Pharmacokinetic and Exposure-Response Analysis of Finerenone: Insights Based on Phase IIb Data and Simulations to Support Dose Selection for Pivotal Trials in Type 2 Diabetes with Chronic Kidney Disease.
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- 2020
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- Publication type:
- journal article
Development of a Paediatric Population-Based Model of the Pharmacokinetics of Rivaroxaban.
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- Clinical Pharmacokinetics, 2014, v. 53, n. 1, p. 89, doi. 10.1007/s40262-013-0090-5
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- Publication type:
- Article
Quantitative systems pharmacology of interferon alpha administration: A multi-scale approach.
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- PLoS ONE, 2019, v. 14, n. 2, p. 1, doi. 10.1371/journal.pone.0209587
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- Article
Model‐Informed Drug Development: Steps Toward Harmonized Guidance.
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- Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 5, p. 954, doi. 10.1002/cpt.3006
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- Article
NT‐proBNP Qualifies as a Surrogate for Clinical End Points in Heart Failure.
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- Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 2, p. 498, doi. 10.1002/cpt.2222
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- Article
Quantitative Systems Pharmacology Approaches for Immuno‐Oncology: Adding Virtual Patients to the Development Paradigm.
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- Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 3, p. 605, doi. 10.1002/cpt.1987
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- Publication type:
- Article
Physiologically based pharmacokinetic modelling of high- and low-dose etoposide: from adults to children.
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- Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 2, p. 397, doi. 10.1007/s00280-011-1706-9
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- Publication type:
- Article
Model‐informed bridging of rivaroxaban doses for thromboprophylaxis in pediatric patients aged 9 years and older with congenital heart disease.
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- CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 8, p. 1111, doi. 10.1002/psp4.12830
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- Article
CKD subpopulations defined by risk‐factors: A longitudinal analysis of electronic health records.
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- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 11, p. 1343, doi. 10.1002/psp4.12695
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- Publication type:
- Article
Population pharmacokinetic analysis of rivaroxaban in children and comparison to prospective physiologically‐based pharmacokinetic predictions.
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- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 10, p. 1195, doi. 10.1002/psp4.12688
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- Publication type:
- Article
Data‐driven personalization of a physiologically based pharmacokinetic model for caffeine: A systematic assessment.
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- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 7, p. 782, doi. 10.1002/psp4.12646
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- Publication type:
- Article
A generic framework for the physiologically‐based pharmacokinetic platform qualification of PK‐Sim and its application to predicting cytochrome P450 3A4–mediated drug–drug interactions.
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- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 6, p. 633, doi. 10.1002/psp4.12636
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- Publication type:
- Article
Open Systems Pharmacology Community—An Open Access, Open Source, Open Science Approach to Modeling and Simulation in Pharmaceutical Sciences.
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- CPT: Pharmacometrics & Systems Pharmacology, 2019, v. 8, n. 12, p. 878, doi. 10.1002/psp4.12473
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- Publication type:
- Article
Application of Physiologically‐Based and Population Pharmacokinetic Modeling for Dose Finding and Confirmation During the Pediatric Development of Moxifloxacin.
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- CPT: Pharmacometrics & Systems Pharmacology, 2019, v. 8, n. 9, p. 654, doi. 10.1002/psp4.12446
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- Article
Establishing a Multidisciplinary Framework to Study Drug‐Drug Interactions of Hormonal Contraceptives: An Invitation to Collaborate.
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- CPT: Pharmacometrics & Systems Pharmacology, 2018, v. 7, n. 11, p. 706, doi. 10.1002/psp4.12357
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- Publication type:
- Article