Works by Liou, Jing-Ping

Results: 52

FGFR inhibitors promote the autophagic degradation of IFN-γ-induced PD-L1 and alleviate the PD-L1-mediated transcriptional suppression of FGFR3-TACC3 in non-muscle-invasive bladder cancer.

Published in:

Cell Death & Disease, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41419-025-07821-8

By:

Lin, Yu-Chen;
Chu, Cheng-Ying;
Hsieh, Tsung-Han;
Lin, Bo-Jyun;
Liou, Jing-Ping;
Yen, Yun;
Chen, Chun-Han

Publication type:

Article

Effect of Sulfotyrosine and Negatively Charged Amino Acid of Leech‐Derived Peptides on Binding and Inhibitory Activity Against Thrombin.

Published in:

ChemBioChem, 2024, v. 25, n. 3, p. 1, doi. 10.1002/cbic.202300744

By:

Chen, Tzu‐Yin;
Shyur, Eileen;
Ma, Tzu‐Hsuan;
Wijeyewickrema, Lakshmi;
Lin, Sheng‐Wei;
Kao, Mu‐Rong;
Liang, Pi‐Hui;
Shie, Jiun‐Jie;
Chuang, Er‐Yuan;
Liou, Jing‐Ping;
Hsieh, Yves S. Y.

Publication type:

Article

A Novel Dual HDAC6 and Tubulin Inhibitor, MPT0B451, Displays Anti-tumor Ability in Human Cancer Cells in Vitro and in Vivo.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00205

By:

Wu, Yi-Wen;
Hsu, Kai-Cheng;
Lee, Hsueh-Yun;
Huang, Tsui-Chin;
Lin, Tony E.;
Chen, Yi-Ling;
Sung, Ting-Yi;
Liou, Jing-Ping;
Hwang-Verslues, Wendy W.;
Pan, Shiow-Lin;
HuangFu, Wei-Chun

Publication type:

Article

MPT0G413, A Novel HDAC6-Selective Inhibitor, and Bortezomib Synergistically Exert Anti-tumor Activity in Multiple Myeloma Cells.

Published in:

Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2019.00249

By:

Huang, Fang-I;
Wu, Yi-Wen;
Sung, Ting-Yi;
Liou, Jing-Ping;
Lin, Mei-Hsiang;
Pan, Shiow-Lin;
Yang, Chia-Ron

Publication type:

Article

Novel dual inhibitor targeting CDC25 and HDAC for treating triple-negative breast cancer.

Published in:

Apoptosis, 2024, v. 29, n. 11/12, p. 2047, doi. 10.1007/s10495-024-02023-7

By:

Sethy, Bidyadhar;
Upadhyay, Richa;
Narwanti, Iin;
Yu, Zih-Yao;
Lee, Sung-Bau;
Liou, Jing-Ping

Publication type:

Article

Optimization and Development of Selective Histone Deacetylase Inhibitor (MPT0B291)-Loaded Albumin Nanoparticles for Anticancer Therapy.

Published in:

Pharmaceutics, 2021, v. 13, n. 10, p. 1728, doi. 10.3390/pharmaceutics13101728

By:

Putri, Athika Darumas;
Chen, Pai-Shan;
Su, Yu-Lin;
Lin, Jia-Pei;
Liou, Jing-Ping;
Hsieh, Chien-Ming

Publication type:

Article

Beyond the vaccines: a glance at the small molecule and peptide-based anti-COVID19 arsenal.

Published in:

Journal of Biomedical Science, 2022, v. 29, n. 1, p. 1, doi. 10.1186/s12929-022-00847-6

By:

Nepali, Kunal;
Sharma, Ram;
Sharma, Sachin;
Thakur, Amandeep;
Liou, Jing-Ping

Publication type:

Article

Beyond the vaccines: a glance at the small molecule and peptide-based anti-COVID19 arsenal.

Published in:

Journal of Biomedical Science, 2022, v. 29, n. 1, p. 1, doi. 10.1186/s12929-022-00847-6

By:

Nepali, Kunal;
Sharma, Ram;
Sharma, Sachin;
Thakur, Amandeep;
Liou, Jing-Ping

Publication type:

Article

Recent developments in epigenetic cancer therapeutics: clinical advancement and emerging trends.

Published in:

Journal of Biomedical Science, 2021, v. 28, n. 1, p. 1, doi. 10.1186/s12929-021-00721-x

By:

Nepali, Kunal;
Liou, Jing-Ping

Publication type:

Article

An updated patent review of histone deacetylase (HDAC) inhibitors in cancer (2020 – present).

Published in:

Expert Opinion on Therapeutic Patents, 2023, v. 33, n. 5, p. 349, doi. 10.1080/13543776.2023.2219393

By:

Liu, Yi-Min;
Liou, Jing-Ping

Publication type:

Article

Anaplastic lymphoma kinase inhibitors: an updated patent review (2014–2018).

Published in:

Expert Opinion on Therapeutic Patents, 2020, v. 30, n. 5, p. 351, doi. 10.1080/13543776.2020.1738389

By:

Liu, Yi-Min;
Kuo, Chun-Nan;
Liou, Jing-Ping

Publication type:

Article

Tubulin inhibitors: a patent review.

Published in:

Expert Opinion on Therapeutic Patents, 2014, v. 24, n. 1, p. 69, doi. 10.1517/13543776.2014.859247

By:

Liu, Yi-Min;
Chen, Hsiao-Ling;
Lee, Hsueh-Yun;
Liou, Jing-Ping

Publication type:

Article

Flavone-based dual PARP-Tubulin inhibitor manifesting efficacy against endometrial cancer.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2276665

By:

Sharma, Sachin;
Chandra, Kavya;
Naik, Aliva;
Sharma, Anamika;
Sharma, Ram;
Thakur, Amandeep;
Grewal, Ajmer Singh;
Dhingra, Ashwani K.;
Banerjee, Arnab;
Liou, Jing Ping;
Guru, Santosh Kumar;
Nepali, Kunal

Publication type:

Article

Effect of 3-subsitution of quinolinehydroxamic acids on selectivity of histone deacetylase isoforms.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 74, doi. 10.1080/14756366.2020.1839446

By:

Mehndiratta, Samir;
Chen, Mei-Chuan;
Chao, Yuh-Hsuan;
Lee, Cheng-Hsin;
Liou, Jing-Ping;
Lai, Mei-Jung;
Lee, Hsueh-Yun

Publication type:

Article

HDAC6 involves in regulating the lncRNA-microRNA-mRNA network to promote the proliferation of glioblastoma cells.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2022, v. 41, n. 1, p. 1, doi. 10.1186/s13046-022-02257-w

By:

Wu, An-Chih;
Yang, Wen-Bin;
Chang, Kwang-Yu;
Lee, Jung-Shun;
Liou, Jing-Ping;
Su, Ruei-Yuan;
Cheng, Siao Muk;
Hwang, Daw-Yang;
Kikkawa, Ushio;
Hsu, Tsung-I;
Wang, Chih-Yang;
Chang, Wen-Chang;
Chen, Pin-Yuan;
Chuang, Jian-Ying

Publication type:

Article

MPT0B098, a Microtubule Inhibitor, Suppresses JAK2/STAT3 Signaling Pathway through Modulation of SOCS3 Stability in Oral Squamous Cell Carcinoma.

Published in:

PLoS ONE, 2016, v. 11, n. 7, p. 1, doi. 10.1371/journal.pone.0158440

By:

Peng, Hsuan-Yu;
Cheng, Yun-Ching;
Hsu, Yuan-Ming;
Wu, Guan-Hsun;
Kuo, Ching-Chuan;
Liou, Jing-Ping;
Chang, Jang-Yang;
Jin, Shiow-Lian Catherine;
Shiah, Shine-Gwo

Publication type:

Article

Early investigational tubulin inhibitors as novel cancer therapeutics.

Published in:

Expert Opinion on Investigational Drugs, 2016, v. 25, n. 8, p. 917, doi. 10.1080/13543784.2016.1189901

By:

Nepali, Kunal;
Ojha, Ritu;
Lee, Hsueh-Yun;
Liou, Jing-Ping

Publication type:

Article

HDAC inhibitor protects chronic cerebral hypoperfusion and oxygen‐glucose deprivation injuries via H3K14 and H4K5 acetylation‐mediated BDNF expression.

Published in:

Journal of Cellular & Molecular Medicine, 2020, v. 24, n. 12, p. 6966, doi. 10.1111/jcmm.15358

By:

Fang, Yao‐Ching;
Chan, Lung;
Liou, Jing‐Ping;
Tu, Yong‐Kwang;
Lai, Mei‐Jung;
Chen, Chin‐I;
Vidyanti, Amelia Nur;
Lee, Hsueh‐Yun;
Hu, Chaur‐Jong

Publication type:

Article

Anticancer Study of a Novel Pan-HDAC Inhibitor MPT0G236 in Colorectal Cancer Cells.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 16, p. 12588, doi. 10.3390/ijms241612588

By:

Tsai, Feng-Lung;
Huang, Han-Li;
Lai, Mei-Jung;
Liou, Jing-Ping;
Pan, Shiow-Lin;
Yang, Chia-Ron

Publication type:

Article

In vitro and in vivo anti-tumour effects of MPT0B014, a novel derivative aroylquinoline, and in combination with erlotinib in human non-small-cell lung cancer cells.

Published in:

British Journal of Pharmacology, 2014, v. 171, n. 1, p. 122, doi. 10.1111/bph.12427

By:

Tsai, An ‐ Chi;
Pai, Hui ‐ Chen;
Wang, Chih ‐ Ya;
Liou, Jing ‐ Ping;
Teng, Che ‐ Ming;
Wang, Jing ‐ Chi;
Pan, Shiow ‐ Lin

Publication type:

Article

Increased activation of HDAC1/2/6 and Sp1 underlies therapeutic resistance and tumor growth in glioblastoma.

Published in:

Neuro-Oncology, 2020, v. 22, n. 10, p. 1439, doi. 10.1093/neuonc/noaa103

By:

Yang, Wen-Bin;
Hsu, Che-Chia;
Hsu, Tsung-I;
Liou, Jing-Ping;
Chang, Kwang-Yu;
Chen, Pin-Yuan;
Liu, Jr-Jiun;
Yang, Shung-Tai;
Wang, Jia-Yi;
Yeh, Shiu-Hwa;
Chen, Ruei-Ming;
Chang, Wen-Chang;
Chuang, Jian-Ying

Publication type:

Article

Pharmacokinetics and protein binding of MPT0B292.

Published in:

Biopharmaceutics & Drug Disposition, 2017, v. 38, n. 5, p. 340, doi. 10.1002/bdd.2067

By:

Tien, Yu‐En;
Li, Chan‐Jung;
Liou, Jing‐Ping;
Chang, Jang‐Yang;
Huang, Jin‐Ding

Publication type:

Article

Targeting Autophagy by MPT0L145, a Highly Potent PIK3C3 Inhibitor, Provides Synergistic Interaction to Targeted or Chemotherapeutic Agents in Cancer Cells.

Published in:

Cancers, 2019, v. 11, n. 9, p. 1345, doi. 10.3390/cancers11091345

By:

Chen, Chun-Han;
Hsieh, Tsung-Han;
Lin, Yu-Chen;
Liu, Yun-Ru;
Liou, Jing-Ping;
Yen, Yun

Publication type:

Article

Novel microtubule inhibitor MPT0B098 inhibits hypoxia-induced epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma.

Published in:

Journal of Biomedical Science, 2018, v. 25, p. 1, doi. 10.1186/s12929-018-0432-6

By:

Tsai, I-Ting;
Kuo, Ching-Chuan;
Liou, Jing-Ping;
Chang, Jang-Yang

Publication type:

Article

1-Arylsulfonyl-5-( N-hydroxyacrylamide)indolines Histone Deacetylase Inhibitors Are Potent Cytokine Release Suppressors.

Published in:

ChemBioChem, 2013, v. 14, n. 10, p. 1248, doi. 10.1002/cbic.201300201

By:

Lee, Hsueh‐Yun;
Yang, Chia‐Ron;
Lai, Mei‐Jung;
Huang, Han‐Li;
Hsieh, Yi‐Ling;
Liu, Yi‐Min;
Yeh, Teng‐Kuang;
Li, Yu‐Hsuan;
Mehndiratta, Samir;
Teng, Che‐Ming;
Liou, Jing‐Ping

Publication type:

Article

Inside Cover: 1-Arylsulfonyl-5-( N-hydroxyacrylamide)indolines Histone Deacetylase Inhibitors Are Potent Cytokine Release Suppressors (ChemBioChem 10/2013).

Published in:

ChemBioChem, 2013, v. 14, n. 10, p. 1150, doi. 10.1002/cbic.201390034

By:

Lee, Hsueh‐Yun;
Yang, Chia‐Ron;
Lai, Mei‐Jung;
Huang, Han‐Li;
Hsieh, Yi‐Ling;
Liu, Yi‐Min;
Yeh, Teng‐Kuang;
Li, Yu‐Hsuan;
Mehndiratta, Samir;
Teng, Che‐Ming;
Liou, Jing‐Ping

Publication type:

Article

MPT0B002, a novel microtubule inhibitor, downregulates T315I mutant Bcr-Abl and induces apoptosis of imatinib-resistant chronic myeloid leukemia cells.

Published in:

Investigational New Drugs, 2017, v. 35, n. 4, p. 427, doi. 10.1007/s10637-017-0457-9

By:

Yeh, Yi-Yen;
Liou, Jing-Ping;
Lee, Yueh-Lun;
Lin, John;
Huang, Huei-Mei

Publication type:

Article

MPT0B169, a New Tubulin Inhibitor, Inhibits Cell Growth and Induces G2/M Arrest in Nonresistant and Paclitaxel-Resistant Cancer Cells.

Published in:

Pharmacology, 2013, v. 92, n. 1/2, p. 90, doi. 10.1159/000351852

By:

Lee, Wei-Hwa;
Liu, Hsinjin Eugene;
Chang, Jang-Yang;
Liou, Jing-Ping;
Huang, Huei-Mei

Publication type:

Article

2-Methoxyestradiol attenuates phosphatidylinositol 3-kinase/Akt pathway-mediated metastasis of gastric cancer.

Published in:

International Journal of Cancer, 2007, v. 121, n. 11, p. 2547, doi. 10.1002/ijc.22963

By:

Lin, Heng-Liang;
Yang, Muh-Hwa;
Wu, Chew-Wun;
Chen, Po-Min;
Yang, Yi-Ping;
Chu, Yue-Ru;
Kao, Chung-Lan;
Ku, Hung-Hai;
Lo, Jen-Fan;
Liou, Jing-Ping;
Chi, Chin-Wen;
Chiou, Shih-Hwa

Publication type:

Article

HDAC6 involves in regulating the lncRNA-microRNA-mRNA network to promote the proliferation of glioblastoma cells.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2022, v. 41, n. 1, p. 1, doi. 10.1186/s13046-022-02257-w

By:

Wu, An-Chih;
Yang, Wen-Bin;
Chang, Kwang-Yu;
Lee, Jung-Shun;
Liou, Jing-Ping;
Su, Ruei-Yuan;
Cheng, Siao Muk;
Hwang, Daw-Yang;
Kikkawa, Ushio;
Hsu, Tsung-I;
Wang, Chih-Yang;
Chang, Wen-Chang;
Chen, Pin-Yuan;
Chuang, Jian-Ying

Publication type:

Article

HDAC6 involves in regulating the lncRNA-microRNA-mRNA network to promote the proliferation of glioblastoma cells.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2022, v. 41, n. 1, p. 1, doi. 10.1186/s13046-022-02257-w

By:

Wu, An-Chih;
Yang, Wen-Bin;
Chang, Kwang-Yu;
Lee, Jung-Shun;
Liou, Jing-Ping;
Su, Ruei-Yuan;
Cheng, Siao Muk;
Hwang, Daw-Yang;
Kikkawa, Ushio;
Hsu, Tsung-I;
Wang, Chih-Yang;
Chang, Wen-Chang;
Chen, Pin-Yuan;
Chuang, Jian-Ying

Publication type:

Article

2-Amino-3,4,5-Trimethoxybenzophenones as Potent Tubulin Polymerization Inhibitors.

Published in:

ChemMedChem, 2011, v. 6, n. 3, p. 450, doi. 10.1002/cmdc.201000479

By:

Chuang, Hsun-Yueh;
Chang, Jang-Yang;
Lai, Mei-Jung;
Kuo, Ching-Chuan;
Lee, Hsueh-Yun;
Hsieh, Hsing-Pang;
Chen, Ying-Jen;
Chen, Li-Tzong;
Pan, Wen-Yu;
Liou, Jing-Ping

Publication type:

Article

Synthesis and Structure-Activity Relationships of 1-Benzyl-4,5,6-trimethoxyindoles as a Novel Class of Potent Antimitotic Agents.

Published in:

ChemMedChem, 2009, v. 4, n. 4, p. 588, doi. 10.1002/cmdc.200800405

By:

Lai, Mei-Jung;
Kuo, Ching-Chuan;
Yeh, Teng-Kuang;
Hsieh, Hsing-Pang;
Chen, Li-Tzong;
Pan, Wen-Yu;
Hsu, Kuang-Yang;
Chang, Jang-Yang;
Liou, Jing-Ping

Publication type:

Article

Structure-Activity Relationship Studies of 3-Aroylindoles as Potent Antimitotic Agents.

Published in:

ChemMedChem, 2006, v. 1, n. 10, p. 1106, doi. 10.1002/cmdc.200600125

By:

Liou, Jing-Ping;
Mahindroo, Neeraj;
Chang, Chun-Wei;
Guo, Fu-Ming;
Lee, Sandy Wen-Hsing;
Tan, Uan-Kang;
Yeh, Teng-Kuang;
Kuo, Ching-Chuan;
Chang, Yi-Wei;
Lu, Ping-Hsun;
Tung, Yen-Shih;
Lin, Ke-Ta;
Chang, Jang-Yang;
Hsieh, Hsing-Pang

Publication type:

Article

Erratum to: A novel tubulin polymerization inhibitor, MPT0B206, downregulates Bcr-Abl expression and induces apoptosis in imatinib-sensitive and imatinib-resistant CML cells.

Published in:

2017

By:

Chen, Chih-Wei;
Lee, Yueh-Lun;
Liou, Jing-Ping;
Liu, Yu-Hsiu;
Liu, Chin-Wei;
Chen, Tsai-Yun;
Huan, Huei-Mei

Publication type:

Erratum

A novel tubulin polymerization inhibitor, MPT0B206, downregulates Bcr-Abl expression and induces apoptosis in imatinib-sensitive and imatinib-resistant CML cells.

Published in:

Apoptosis, 2016, v. 21, n. 9, p. 1008, doi. 10.1007/s10495-016-1264-z

By:

Chen, Chih-Wei;
Lee, Yueh-Lun;
Liou, Jing-Ping;
Liu, Yu-Hsiu;
Liu, Chin-Wei;
Chen, Tsai-Yun;
Huang, Huei-Mei

Publication type:

Article

Denbinobin upregulates miR-146a expression and attenuates IL-1β-induced upregulation of ICAM-1 and VCAM-1 expressions in osteoarthritis fibroblast-like synoviocytes.

Published in:

Journal of Molecular Medicine, 2014, v. 92, n. 11, p. 1147, doi. 10.1007/s00109-014-1192-8

By:

Yang, Chia-Ron;
Shih, Kao-Shang;
Liou, Jing-Ping;
Wu, Yi-Wen;
Hsieh, I-Ni;
Lee, Hsueh-Yun;
Lin, Tzu-Cheng;
Wang, Jyh-Horng

Publication type:

Article

A novel dual HDAC and HSP90 inhibitor, MPT0G449, downregulates oncogenic pathways in human acute leukemia in vitro and in vivo.

Published in:

Oncogenesis, 2021, v. 10, n. 5, p. 1, doi. 10.1038/s41389-021-00331-0

By:

Wu, Yi-Wen;
Chao, Min-Wu;
Tu, Huang-Ju;
Chen, Liang-Chieh;
Hsu, Kai-Cheng;
Liou, Jing-Ping;
Yang, Chia-Ron;
Yen, Shih-Chung;
HuangFu, Wei-Chun;
Pan, Shiow-Lin

Publication type:

Article

Combining an Autophagy Inhibitor, MPT0L145, with Abemaciclib Is a New Therapeutic Strategy in GBM Treatment.

Published in:

Cancers, 2021, v. 13, n. 23, p. 6117, doi. 10.3390/cancers13236117

By:

Hsieh, Tsung-Han;
Liang, Muh-Lii;
Zheng, Jia-Huei;
Lin, Yu-Chen;
Yang, Yu-Chen;
Vo, Thanh-Hoa;
Liou, Jing-Ping;
Yen, Yun;
Chen, Chun-Han

Publication type:

Article

Scaffold hopping approaches for dual-target antitumor drug discovery: opportunities and challenges.

Published in:

Expert Opinion on Drug Discovery, 2024, v. 19, n. 11, p. 1355, doi. 10.1080/17460441.2024.2409674

By:

Mishra, Anshul;
Thakur, Amandeep;
Sharma, Ram;
Onuku, Raphael;
Kaur, Charanjit;
Liou, Jing Ping;
Hsu, Sung-Po;
Nepali, Kunal

Publication type:

Article

Prudent tactics to sail the boat of PARP inhibitors as therapeutics for diverse malignancies.

Published in:

Expert Opinion on Drug Discovery, 2023, v. 18, n. 10, p. 1169, doi. 10.1080/17460441.2023.2241818

By:

Rana, Mandeep;
Thakur, Amandeep;
Kaur, Charanjit;
Pan, Chun-Hsu;
Lee, Sung-Bau;
Liou, Jing Ping;
Nepali, Kunal

Publication type:

Article

MT-4 Suppresses Resistant Ovarian Cancer Growth through Targeting Tubulin and HSP27.

Published in:

PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0123819

By:

Pai, Hui Chen;
Kumar, Sunil;
Shen, Chien-Chang;
Liou, Jing Ping;
Pan, Shiow Lin;
Teng, Che Ming

Publication type:

Article

Intermediary Metabolite Precursor Dimethyl-2-Ketoglutarate Stabilizes Hypoxia-Inducible Factor-1α by Inhibiting Prolyl-4-Hydroxylase PHD2.

Published in:

PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0113865

By:

Hou, Peifeng;
Kuo, Ching-Ying;
Cheng, Chun-Ting;
Liou, Jing-Ping;
Ann, David K.;
Chen, Qiang

Publication type:

Article

A Novel Synthetic Microtubule Inhibitor, MPT0B214 Exhibits Antitumor Activity in Human Tumor Cells through Mitochondria-Dependent Intrinsic Pathway.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0058953

By:

Chiang, Nai-Jung;
Lin, Ching-I;
Liou, Jing-Ping;
Kuo, Ching-Chuan;
Chang, Chi-Yen;
Chen, Li-Tzong;
Chang, Jang-Yang

Publication type:

Article

Anti-Arthritic Effects of Magnolol in Human Interleukin 1β-Stimulated Fibroblast-Like Synoviocytes and in a Rat Arthritis Model.

Published in:

PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031368

By:

Wang, Jyh-Horng;
Shih, Kao-Shang;
Liou, Jing-Ping;
Wu, Yi-Wen;
Chang, Anita Shin-Yuan;
Wang, Kang-Li;
Tsai, Ching-Lin;
Yang, Chia-Ron

Publication type:

Article

Anti-leukemia effects of the novel synthetic 1-benzylindole derivative 21-900 in vitro and in vivo.

Published in:

Scientific Reports, 2017, p. 42291, doi. 10.1038/srep42291

By:

HuangFu, Wei-Chun;
Chao, Min-Wu;
Cheng, Chun-Chun;
Wei, Yu-Chieh;
Wu, Yi-Wen;
Liou, Jing-Ping;
Hsiao, George;
Lee, Yu-Ching;
Yang, Chia-Ron

Publication type:

Article

MPT0G066, a novel anti-mitotic drug, induces JNK-independent mitotic arrest, JNK-mediated apoptosis, and potentiates antineoplastic effect of cisplatin in ovarian cancer.

Published in:

Scientific Reports, 2016, p. 31664, doi. 10.1038/srep31664

By:

Huang, Han-Li;
Chao, Min-Wu;
Li, Ya-Chi;
Chang, Li-Hsun;
Chen, Chun-Han;
Chen, Mei-Chuan;
Cheng, Chun-Chun;
Liou, Jing-Ping;
Teng, Che-Ming;
Pan, Shiow-Lin

Publication type:

Article

LTP-1, a novel antimitotic agent and Stat3 inhibitor, inhibits human pancreatic carcinomas in vitro and in vivo.

Published in:

Scientific Reports, 2016, p. 27794, doi. 10.1038/srep27794

By:

Huang, Han-Li;
Chao, Min-Wu;
Chen, Chung-Chun;
Cheng, Chun-Chun;
Chen, Mei-Chuan;
Lin, Chao-Feng;
Liou, Jing-Ping;
Teng, Che-Ming;
Pan, Shiow-Lin

Publication type:

Article

Histone deacetylase 6 acts upstream of DNA damage response activation to support the survival of glioblastoma cells.

Published in:

Cell Death & Disease, 2021, v. 12, n. 10, p. 1, doi. 10.1038/s41419-021-04182-w

By:

Yang, Wen-Bin;
Wu, An-Chih;
Hsu, Tsung-I;
Liou, Jing-Ping;
Lo, Wei-Lun;
Chang, Kwang-Yu;
Chen, Pin-Yuan;
Kikkawa, Ushio;
Yang, Shung-Tai;
Kao, Tzu-Jen;
Chen, Ruei-Ming;
Chang, Wen-Chang;
Ko, Chiung-Yuan;
Chuang, Jian-Ying

Publication type:

Article

The novel histone de acetylase 6 inhibitor, MPT0G211, ameliorates tau phosphorylation and cognitive deficits in an Alzheimer’s disease model.

Published in:

Cell Death & Disease, 2018, v. 9, n. 6, p. 1, doi. 10.1038/s41419-018-0688-5

By:

Fan, Sheng-Jun;
Huang, Fang-I;
Liou, Jing-Ping;
Yang, Chia-Ron

Publication type:

Article