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A green Heck reaction protocol towards trisubstituted alkenes, versatile pharmaceutical intermediates.
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- Frontiers in Chemistry, 2024, p. 1, doi. 10.3389/fchem.2024.1431382
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- Article
Discovery of RC-752, a Novel Sigma-1 Receptor Antagonist with Antinociceptive Activity: A Promising Tool for Fighting Neuropathic Pain.
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- Pharmaceuticals (14248247), 2023, v. 16, n. 7, p. 962, doi. 10.3390/ph16070962
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- Article
Evidence of Pyrimethamine and Cycloguanil Analogues as Dual Inhibitors of Trypanosoma brucei Pteridine Reductase and Dihydrofolate Reductase.
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- Pharmaceuticals (14248247), 2021, v. 14, n. 7, p. 636, doi. 10.3390/ph14070636
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- Article
4-Amino-1,2,4-triazole-3-thione as a Promising Scaffold for the Inhibition of Serine and Metallo-β-Lactamases.
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- Pharmaceuticals (14248247), 2020, v. 13, n. 3, p. 52, doi. 10.3390/ph13030052
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- Article
BS148 Reduces the Aggressiveness of Metastatic Melanoma via Sigma-2 Receptor Targeting.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 11, p. 9684, doi. 10.3390/ijms24119684
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- Article
From Nature to Synthetic Compounds: Novel 1(N),2,3 Trisubstituted-5-oxopyrrolidines Targeting Multiple Myeloma Cells.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 13061, doi. 10.3390/ijms232113061
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- Article
Sigma-1 Receptor Agonists Acting on Aquaporin-Mediated H 2 O 2 Permeability: New Tools for Counteracting Oxidative Stress.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 18, p. 9790, doi. 10.3390/ijms22189790
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- Article
Setup and Validation of a Reliable Docking Protocol for the Development of Neuroprotective Agents by Targeting the Sigma-1 Receptor (S1R).
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- International Journal of Molecular Sciences, 2020, v. 21, n. 20, p. 7708, doi. 10.3390/ijms21207708
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- Article
Optimization of N‐alkylation in the Synthesis of Methotrexate and Pteridine‐based Derivatives Under Microwave‐Irradiation.
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- ChemistrySelect, 2019, v. 4, n. 15, p. 4429, doi. 10.1002/slct.201900721
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- Article
Geometric Isomerism of an Acetamidino Derivative Determined by NMR Investigations.
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- ChemistrySelect, 2017, v. 2, n. 30, p. 9706, doi. 10.1002/slct.201701646
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- Article
Phenylboronic Acids Probing Molecular Recognition against Class A and Class C β-lactamases.
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- Antibiotics (2079-6382), 2019, v. 8, n. 4, p. 171, doi. 10.3390/antibiotics8040171
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- Article
Phenylboronic Acid Derivatives as Validated Leads Active in Clinical Strains Overexpressing KPC‐2: A Step against Bacterial Resistance.
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- ChemMedChem, 2018, v. 13, n. 7, p. 713, doi. 10.1002/cmdc.201700788
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- Article
Effects of Bisphenols on RACK1 Expression and Their Immunological Implications in THP-1 Cells.
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- Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.743991
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- Article
Chiral 2‐phenyl‐3‐hydroxypropyl esters as PKC‐alpha modulators: HPLC enantioseparation, NMR absolute configuration assignment, and molecular docking studies.
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- Chirality, 2022, v. 34, n. 3, p. 498, doi. 10.1002/chir.23406
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- Article
Peptides as Therapeutic Agents: Challenges and Opportunities in the Green Transition Era.
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- Molecules, 2023, v. 28, n. 20, p. 7165, doi. 10.3390/molecules28207165
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- Article
Structural Insights into the Ligand–LsrK Kinase Binding Mode: A Step Forward in the Discovery of Novel Antimicrobial Agents.
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- Molecules, 2023, v. 28, n. 6, p. 2542, doi. 10.3390/molecules28062542
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- Article
Repurposing the Antiplatelet Agent Ticlopidine to Counteract the Acute Phase of ER Stress Condition: An Opportunity for Fighting Coronavirus Infections and Cancer.
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- Molecules, 2022, v. 27, n. 14, p. N.PAG, doi. 10.3390/molecules27144327
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- Article
First virtual screening and experimental validation of inhibitors targeting GES-5 carbapenemase.
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- Journal of Computer-Aided Molecular Design, 2019, v. 33, n. 2, p. 295, doi. 10.1007/s10822-018-0182-2
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- Article
High‐resolution crystal structure of Trypanosoma brucei pteridine reductase 1 in complex with an innovative tricyclic‐based inhibitor.
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- Acta Crystallographica: Section D, Structural Biology, 2020, v. 76, n. 6, p. 558, doi. 10.1107/S2059798320004891
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- Article
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth.
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- eLife, 2023, p. 1, doi. 10.7554/eLife.73862
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- Article
Identification of a new cannabidiol n-hexyl homolog in a medicinal cannabis variety with an antinociceptive activity in mice: cannabidihexol.
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- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-79042-2
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- Article
Cannabinoid Profiling of Hemp Seed Oil by Liquid Chromatography Coupled to High-Resolution Mass Spectrometry.
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- Frontiers in Plant Science, 2019, p. N.PAG, doi. 10.3389/fpls.2019.00120
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- Article
Neurodegeneration: can metabolites from Eremurus persicus help?
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1309766
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- Article
Microwave-Assisted Extraction and HPLC-UV-CD Determination of (S)-usnic Acid in Cladonia foliacea.
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- Molecules, 2021, v. 26, n. 2, p. 455, doi. 10.3390/molecules26020455
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- Article
Cyclic Peptides Acting as Allosteric Inhibitors of Human Thymidylate Synthase and Cancer Cell Growth.
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- Molecules, 2019, v. 24, n. 19, p. 3493, doi. 10.3390/molecules24193493
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- Article
In silico identification and experimental validation of hits active against KPC-2 β-lactamase.
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- PLoS ONE, 2018, v. 13, n. 11, p. 1, doi. 10.1371/journal.pone.0203241
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- Article
Could the Oxidation of α1-Antitrypsin Prevent the Binding of Human Neutrophil Elastase in COVID-19 Patients?
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- International Journal of Molecular Sciences, 2023, v. 24, n. 17, p. 13533, doi. 10.3390/ijms241713533
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- Article
Short- and Long-Term Regulation of HuD: A Molecular Switch Mediated by Folic Acid?
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- International Journal of Molecular Sciences, 2023, v. 24, n. 15, p. 12201, doi. 10.3390/ijms241512201
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- Article