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Selective PROTAC-mediated degradation of SMARCA2 is efficacious in SMARCA4 mutant cancers.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34562-5
By:
- Cantley, Jennifer;
- Ye, Xiaofen;
- Rousseau, Emma;
- Januario, Tom;
- Hamman, Brian D.;
- Rose, Christopher M.;
- Cheung, Tommy K.;
- Hinkle, Trent;
- Soto, Leofal;
- Quinn, Connor;
- Harbin, Alicia;
- Bortolon, Elizabeth;
- Chen, Xin;
- Haskell, Roy;
- Lin, Eva;
- Yu, Shang-Fan;
- Del Rosario, Geoff;
- Chan, Emily;
- Dunlap, Debra;
- Koeppen, Hartmut
Publication type:
Article
Distinct resistance mechanisms arise to allosteric vs. ATP-competitive AKT inhibitors.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29655-0
By:
- Savill, Kristin M. Zimmerman;
- Lee, Brian B.;
- Oeh, Jason;
- Lin, Jie;
- Lin, Eva;
- Chung, Wei-Jen;
- Young, Amy;
- Chen, Wennie;
- Miś, Monika;
- Mesh, Kathryn;
- Eastham, Jeffrey;
- Gnad, Florian;
- Jiang, Zhaoshi;
- Stawiski, Eric W.;
- Haley, Benjamin;
- Daemen, Anneleen;
- Wang, Xiaojing;
- Koeppen, Hartmut;
- Modrusan, Zora;
- Martin, Scott E.
Publication type:
Article
Targeting MCL‐1 and BCL‐2 with polatuzumab vedotin and venetoclax overcomes treatment resistance in R/R non‐Hodgkin lymphoma: Results from preclinical models and a Phase Ib study.
Published in:
American Journal of Hematology, 2023, v. 98, n. 3, p. 449, doi. 10.1002/ajh.26809
By:
- Lasater, Elisabeth A.;
- Amin, Dhara N.;
- Bannerji, Rajat;
- Mali, Raghuveer Singh;
- Barrett, Kathy;
- Rys, Ryan N.;
- Oeh, Jason;
- Lin, Eva;
- Sterne‐Weiler, Tim;
- Ingalla, Ellen Rei;
- Go, MaryAnn;
- Yu, Shang‐Fan;
- Krem, Maxwell M.;
- Arthur, Chris;
- Hahn, Uwe;
- Johnston, Anna;
- Karur, Vinit;
- Khan, Nadia;
- Marlton, Paula;
- Phillips, Tycel
Publication type:
Article
Autocrine CSF-1R activation promotes Src-dependent disruption of mammary epithelial architecture.
Published in:
Journal of Cell Biology, 2004, v. 165, n. 2, p. 263, doi. 10.1083/jcb.200309102
By:
- Wrobel, Carolyn N.;
- Debnath, Jayanta;
- Lin, Eva;
- Beausoleil, Sean;
- Roussel, Martine F.;
- Brugge, Joan S.
Publication type:
Article
Effects of GDNF on 6-OHDA-induced death in a dopaminergic cell line: Modulation by inhibitors of PI3 kinase and MEK.
Published in:
Journal of Neuroscience Research, 2003, v. 73, n. 1, p. 105, doi. 10.1002/jnr.10632
By:
- Susana D. Ugarte;
- Eva Lin;
- Eric Klann;
- Michael J. Zigmond;
- Ruth G. Perez
Publication type:
Article
Computational Modeling of Drug Response Identifies Mutant-Specific Constraints for Dosing panRAF and MEK Inhibitors in Melanoma.
Published in:
Cancers, 2024, v. 16, n. 16, p. 2914, doi. 10.3390/cancers16162914
By:
- Goetz, Andrew;
- Shanahan, Frances;
- Brooks, Logan;
- Lin, Eva;
- Mroue, Rana;
- Dela Cruz, Darlene;
- Hunsaker, Thomas;
- Czech, Bartosz;
- Dixit, Purushottam;
- Segal, Udi;
- Martin, Scott;
- Foster, Scott A.;
- Gerosa, Luca
Publication type:
Article
Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors.
Published in:
Nature, 2012, v. 487, n. 7408, p. 505, doi. 10.1038/nature11249
By:
- Wilson, Timothy R.;
- Fridlyand, Jane;
- Yan, Yibing;
- Penuel, Elicia;
- Burton, Luciana;
- Chan, Emily;
- Peng, Jing;
- Lin, Eva;
- Wang, Yulei;
- Sosman, Jeff;
- Ribas, Antoni;
- Li, Jiang;
- Moffat, John;
- Sutherlin, Daniel P.;
- Koeppen, Hartmut;
- Merchant, Mark;
- Neve, Richard;
- Settleman, Jeff
Publication type:
Article
Evaluation of statistical approaches for association testing in noisy drug screening data.
Published in:
BMC Bioinformatics, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12859-022-04693-z
By:
- Smirnov, Petr;
- Smith, Ian;
- Safikhani, Zhaleh;
- Ba-alawi, Wail;
- Khodakarami, Farnoosh;
- Lin, Eva;
- Yu, Yihong;
- Martin, Scott;
- Ortmann, Janosch;
- Aittokallio, Tero;
- Hafner, Marc;
- Haibe-Kains, Benjamin
Publication type:
Article
Correction: Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors.
Published in:
2018
By:
- Merchant, Mark;
- Moffat, John;
- Schaefer, Gabriele;
- Chan, Jocelyn;
- Wang, Xi;
- Orr, Christine;
- Cheng, Jason;
- Hunsaker, Thomas;
- Shao, Lily;
- Wang, Stephanie J.;
- Wagle, Marie-Claire;
- Lin, Eva;
- Haverty, Peter M.;
- Shahidi-Latham, Sheerin;
- Ngu, Hai;
- Solon, Margaret;
- Eastham-Anderson, Jeffrey;
- Koeppen, Hartmut;
- Huang, Shih-Min A.;
- Schwarz, Jacob
Publication type:
Correction Notice
Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors.
Published in:
PLoS ONE, 2017, v. 12, n. 10, p. 1, doi. 10.1371/journal.pone.0185862
By:
- Merchant, Mark;
- Moffat, John;
- Schaefer, Gabriele;
- Chan, Jocelyn;
- Wang, Xi;
- Orr, Christine;
- Cheng, Jason;
- Hunsaker, Thomas;
- Shao, Lily;
- Wang, Stephanie J.;
- Wagle, Marie-Claire;
- Lin, Eva;
- Haverty, Peter M.;
- Shahidi-Latham, Sheerin;
- Ngu, Hai;
- Solon, Margaret;
- Eastham-Anderson, Jeffrey;
- Koeppen, Hartmut;
- Huang, Shih-Min A.;
- Schwarz, Jacob
Publication type:
Article
Reproducibility of Renal Length Measurements with <sup>99m</sup>Tc-DSMA SPECT.
Published in:
Journal of Nuclear Medicine, 2000, v. 41, n. 10, p. 1632
By:
- Lin, Eva;
- Connolly, Leonard P.;
- Zurakowski, David;
- DiCanzio, James;
- Drubach, Laura;
- Mitchell, Karl;
- Tetrault, Tracy;
- Laffin, Stephen P.;
- Treves, S. Ted
Publication type:
Article
Effect of Early Emptying on Quantitation and Interpretation of Liquid Gastric Emptying Studies of Infants and Young Children.
Published in:
Journal of Nuclear Medicine, 2000, v. 41, n. 4, p. 596
By:
- Lin, Eva;
- Connolly, Leonard P.;
- Drubach, Laura;
- Zurakowski, David;
- DiCanzio, James;
- Mitchell, Karl;
- Treves, S. Ted
Publication type:
Article

Found: 12