Works by Lima, Christopher D.

Results: 26

A molecular basis for phosphorylation-dependent SUMO conjugation by the E2 UBC9.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 9, p. 945, doi. 10.1038/nsmb.1648

By:

Mohideen, Firaz;
Capili, Allan D.;
Bilimoria, Parizad M.;
Yamada, Tomoko;
Bonni, Azad;
Lima, Christopher D.

Publication type:

Article

Structural basis for nick recognition by a minimal pluripotent DNA ligase.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 8, p. 770, doi. 10.1038/nsmb1266

By:

Nair, Pravin A.;
Nandakumar, Jayakrishnan;
Smith, Paul;
Odell, Mark;
Lima, Christopher D.;
Shuman, Stewart

Publication type:

Article

Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 12, p. 1060, doi. 10.1038/nsmb1168

By:

Reverter, David;
Lima, Christopher D.

Publication type:

Article

Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 6, p. 491, doi. 10.1038/nsmb1104

By:

Yunus, Ali A;
Lima, Christopher D

Publication type:

Article

Crystal structure of the Schizosaccharomyces pombe U7BR E2‐binding region in complex with Ubc7.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2019, v. 75, n. 8, p. 552, doi. 10.1107/S2053230X19009786

By:

Hann, Zachary S.;
Metzger, Meredith B.;
Weissman, Allan M.;
Lima, Christopher D.

Publication type:

Article

DNA asymmetry promotes SUMO modification of the single‐stranded DNA‐binding protein RPA.

Published in:

EMBO Journal, 2021, v. 40, n. 22, p. 1, doi. 10.15252/embj.2019103787

By:

Cappadocia, Laurent;
Kochańczyk, Tomasz;
Lima, Christopher D

Publication type:

Article

Protein modification by SUMO, a small ubiquitin-like modifier.

Published in:

FASEB Journal, 2007, v. 21, n. 5, p. A207

By:

Lima, Christopher D.

Publication type:

Article

Inducing interactions with the CTD.

Published in:

Nature Structural & Molecular Biology, 2005, v. 12, n. 2, p. 102, doi. 10.1038/nsmb0205-102

By:

Lima, Christopher D

Publication type:

Article

Enzymology of RNA cap synthesis.

Published in:

Wiley Interdisciplinary Reviews: RNA, 2010, v. 1, n. 1, p. 152, doi. 10.1002/wrna.19

By:

Ghosh, Agnidipta;
Lima, Christopher D.

Publication type:

Article

Crystal structures of two putative phosphoheptose isomerases.

Published in:

Proteins, 2006, v. 63, n. 4, p. 1092, doi. 10.1002/prot.20908

By:

Seetharaman, Jayaraman;
Rajashankar, Kanagalaghatta R.;
Solorzano, Veronica;
Kniewel, Ryan;
Lima, Christopher D.;
Bonanno, Jeffrey B.;
Burley, Stephen K.;
Swaminathan, Subramanyam

Publication type:

Article

Three-dimensional structure of the 67k N-terminal fragment of E. coli DNA topoisomerase I.

Published in:

Nature, 1994, v. 367, n. 6459, p. 138, doi. 10.1038/367138a0

By:

Lima, Christopher D.;
Wang, James C.

Publication type:

Article

Structure and mechanism of T4 polynucleotide kinase: an RNA repair enzyme.

Published in:

EMBO Journal, 2002, v. 21, n. 14, p. 3873, doi. 10.1093/emboj/cdf397

By:

Li Kai Wang;
Lima, Christopher D.;
Shuman, Stewart

Publication type:

Article

Conformational changes in E. coli DNA topoisomerase I.

Published in:

Nature Structural Biology, 1999, v. 6, n. 10, p. 918

By:

Feinberg, Hadar;
Lima, Christopher D.;
Mondragón, Alfonso

Publication type:

Article

Specific and Covalent Targeting of Conjugating and Deconjugating Enzymes of Ubiquitin-Like Proteins.

Published in:

Molecular & Cellular Biology, 2004, v. 24, n. 1, p. 84, doi. 10.1128/MCB.24.1.84-95.2004

By:

Hemelaar, Joris;
Borodovsky, Anna;
Kessler, Benedikt M.;
Reverter, David;
Cook, Julie;
Kolli, Nagamallesawari;
Gan-Erdene, Tudev;
Wilkinson, Keith D.;
Gill, Grace;
Lima, Christopher D.;
Ploegh, Hidde L.;
Ovaa, Huib

Publication type:

Article

Chemical Tools for Probing the Ub/Ubl Conjugation Cascades.

Published in:

ChemBioChem, 2025, v. 26, n. 1, p. 1, doi. 10.1002/cbic.202400659

By:

Kochańczyk, Tomasz;
Fishman, Michael;
Lima, Christopher D.

Publication type:

Article

Active site remodelling accompanies thioester bond formation in the SUMO E1.

Published in:

Nature, 2010, v. 463, n. 7283, p. 906, doi. 10.1038/nature08765

By:

Olsen, Shaun K.;
Capili, Allan D.;
Lu, Xuequan;
Tan, Derek S.;
Lima, Christopher D.

Publication type:

Article

Insights into E3 ligase activity revealed by a SUMO–RanGAP1–Ubc9–Nup358 complex.

Published in:

Nature, 2005, v. 435, n. 7042, p. 687, doi. 10.1038/nature03588

By:

Reverter, David;
Lima, Christopher D.

Publication type:

Article

The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition.

Published in:

Nature Reviews Molecular Cell Biology, 2010, v. 11, n. 12, p. 861, doi. 10.1038/nrm3011

By:

Gareau, Jaclyn R.;
Lima, Christopher D.

Publication type:

Article

SARS hCoV papain-like protease is a unique Lys<sup>48</sup> linkage-specific di-distributive deubiquitinating enzyme.

Published in:

Biochemical Journal, 2015, v. 468, n. 2, p. 215, doi. 10.1042/BJ20141170

By:

Békés, Miklós;
Rut, Wioletta;
Kasperkiewicz, Paulina;
Mulder, Monique P. C.;
Ovaa, Huib;
Drag, Marcin;
Lima, Christopher D.;
Huang, Tony T.

Publication type:

Article

Structure of an Rrp6-RNA exosome complex bound to poly(A) RNA.

Published in:

Nature, 2014, v. 511, n. 7510, p. 435, doi. 10.1038/nature13406

By:

Wasmuth, Elizabeth V.;
Januszyk, Kurt;
Lima, Christopher D.

Publication type:

Article

Structural biology: A protein engagement RING.

Published in:

Nature, 2012, v. 489, n. 7414, p. 43, doi. 10.1038/489043a

By:

Lima, Christopher D.;
Schulman, Brenda A.

Publication type:

Article

Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2.

Published in:

Nature, 2012, v. 483, n. 7387, p. 59, doi. 10.1038/nature10883

By:

Armstrong, Anthony A.;
Mohideen, Firaz;
Lima, Christopher D.

Publication type:

Article

ketu mutant mice uncover an essential meiotic function for the ancient RNA helicase YTHDC2.

Published in:

eLife, 2018, p. 1, doi. 10.7554/eLife.30919

By:

Jain, Devanshi;
Puno, M. Rhyan;
Meydan, Cem;
Lailler, Nathalie;
Mason, Christopher E.;
Lima, Christopher D.;
Anderson, Kathryn V.;
Keeney, Scott

Publication type:

Article

The Rrp6 C-terminal domain binds RNA and activates the nuclear RNA exosome.

Published in:

Nucleic Acids Research, 2017, v. 45, n. 2, p. 846, doi. 10.1093/nar/gkw1152

By:

Wasmuth, Elizabeth V.;
Lima, Christopher D.

Publication type:

Article

Structural genomics: A pipeline for providing structures for the biologist.

Published in:

Protein Science: A Publication of the Protein Society, 2002, v. 11, n. 4, p. 723, doi. 10.1110/ps.4570102

By:

Chance, Mark R.;
Bresnick, Anne R.;
Burley, Stephen K.;
Jiang, Jian-Sheng;
Lima, Christopher D.;
Sali, Andrej;
Almo, Steven C.;
Bonanno, Jeffrey B.;
Buglino, John A.;
Boulton, Simon;
Chen, Hua;
Eswar, Narayanan;
He, Guoshun;
Huang, Raymond;
Ilyin, Valentin;
McMahan, Linda;
Pieper, Ursula;
Ray, Soumya;
Vidal, Marc;
Wang, Li Kai

Publication type:

Article

Structures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1.

Published in:

EMBO Journal, 2005, v. 24, n. 3, p. 439, doi. 10.1038/sj.emboj.7600552

By:

Lois, Luisa Maria;
Lima, Christopher D

Publication type:

Article