Works by Ligon, Azra H.

Results: 27

Distribution of copy number alterations and impact of chromosome arm call thresholds for meningioma.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60734-0

By:

Patel, Ruchit V.;
Ghosh, Hia S.;
Meredith, David M.;
Ryall, Scott;
Claus, Elizabeth B.;
Beroukhim, Rameen;
Ligon, Azra H.;
Santagata, Sandro;
Bi, Wenya Linda

Publication type:

Article

CDK8 is a colorectal cancer oncogene that regulates β-catenin activity.

Published in:

Nature, 2008, v. 455, n. 7212, p. 547, doi. 10.1038/nature07179

By:

Firestein, Ron;
Bass, Adam J.;
So Young Kim;
Dunn, Ian F.;
Silver, Serena J.;
Guney, Isil;
Freed, Ellen;
Ligon, Azra H.;
Vena, Natalie;
Ogino, Shuji;
Chheda, Milan G.;
Tamayo, Pablo;
Finn, Stephen;
Shrestha, Yashaswi;
Boehm, Jesse S.;
Jain, Supriya;
Bojarski, Emeric;
Mermel, Craig;
Barretina, Jordi;
Chan, Jennifer A.

Publication type:

Article

Identification of female carriers for Duchenne and Becker muscular dystrophies using a FISH-based approach.

Published in:

European Journal of Human Genetics, 2000, v. 8, n. 4, p. 293, doi. 10.1038/sj.ejhg.5200450

By:

Ligon, Azra H;
Kashork, Catherine D;
Richards, C Sue;
Shaffer, Lisa G

Publication type:

Article

Case Report: Next generation sequencing identifies a NAB2-STAT6 fusion in Glioblastoma.

Published in:

Diagnostic Pathology, 2016, v. 11, p. 1, doi. 10.1186/s13000-016-0455-9

By:

Diamandis, Phedias;
Ferrer-Luna, Ruben;
Huang, Raymond Y.;
Folkerth, Rebecca D.;
Ligon, Azra H.;
Wen, Patrick Y.;
Beroukhim, Rameen;
Ligon, Keith L.;
Ramkissoon, Shakti H.

Publication type:

Article

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis.

Published in:

Nature Genetics, 2011, v. 43, n. 9, p. 869, doi. 10.1038/ng.890

By:

Locasale, Jason W.;
Grassian, Alexandra R.;
Melman, Tamar;
Lyssiotis, Costas A.;
Mattaini, Katherine R.;
Bass, Adam J.;
Heffron, Gregory;
Metallo, Christian M.;
Muranen, Taru;
Sharfi, Hadar;
Sasaki, Atsuo T.;
Anastasiou, Dimitrios;
Mullarky, Edouard;
Vokes, Natalie I.;
Sasaki, Mika;
Beroukhim, Rameen;
Stephanopoulos, Gregory;
Ligon, Azra H.;
Meyerson, Matthew;
Richardson, Andrea L.

Publication type:

Article

Leiomyomata: heritability and cytogenetic studies.

Published in:

Human Reproduction Update, 2001, v. 7, n. 1, p. 8, doi. 10.1093/humupd/7.1.8

By:

Ligon, Azra H.;
Morton, Cynthia C.

Publication type:

Article

Corrigendum to: LTBK-01. Updates On The Phase Ii And Re-treatment Study Of AZD6244 (Selumetinib) For Children With Recurrent Or Refractory Pediatric Low Grade Glioma: A Pediatric Brain Tumor Consortium (PBTC) Study.

Published in:

Neuro-Oncology, 2022, v. 24, n. 8, p. 1404, doi. 10.1093/neuonc/noac029

By:

Fangusaro, Jason R;
Onar-Thomas, Arzu;
Poussaint, Tina Young;
Wu, Shengjie;
Ligon, Azra H;
Lindeman, Neal Ian;
Banerjee, Anuradha;
Packer, Roger;
Kilburn, Lindsay B;
Pollack, Ian F;
Qaddoumi, Ibrahim A;
Fisher, Paul Graham;
Dhall, Girish;
Baxter, Patricia Ann;
Kreissman, Susan G;
Doyle, L Austin;
Smith, Malcolm A;
Fouladi, Maryam;
Dunkel, Ira J

Publication type:

Article

A phase II trial of selumetinib in children with recurrent optic pathway and hypothalamic low-grade glioma without NF1: a Pediatric Brain Tumor Consortium study.

Published in:

Neuro-Oncology, 2021, v. 23, n. 10, p. 1777, doi. 10.1093/neuonc/noab047

By:

Fangusaro, Jason;
Onar-Thomas, Arzu;
Poussaint, Tina Young;
Wu, Shengjie;
Ligon, Azra H;
Lindeman, Neal;
Campagne, Olivia;
Banerjee, Anu;
Gururangan, Sridharan;
Kilburn, Lindsay B;
Goldman, Stewart;
Qaddoumi, Ibrahim;
Baxter, Patricia;
Vezina, Gilbert;
Bregman, Corey;
Patay, Zoltan;
Jones, Jeremy Y;
Stewart, Clinton F;
Fisher, Michael J;
Doyle, Laurence Austin

Publication type:

Article

HMGA2 expression in uterine leiomyomata and myometrium: Quantitative analysis and tissue culture studies.

Published in:

Genes, Chromosomes & Cancer, 2003, v. 38, n. 1, p. 68, doi. 10.1002/gcc.10240

By:

Karen L. Gross;
David M. Neskey;
Nitasha Manchanda;
Stanislawa Weremowicz;
Michael S. Kleinman;
Romana A. Nowak;
Azra H. Ligon;
Piere Rogalla;
Klaus Drechsler;
Jörn Bullerdiek

Publication type:

Article

Genetics of uterine leiomyomata.

Published in:

Genes, Chromosomes & Cancer, 2000, v. 28, n. 3, p. 235, doi. 10.1002/1098-2264(200007)28:3<235::AID-GCC1>3.0.CO;2-7

By:

Ligon, Azra H.;
Morton, Cynthia C.

Publication type:

Article

Dysregulation of HMGIC in a uterine lipoleiomyoma with a complex rearrangement including chromosomes 7, 12, and 14.

Published in:

Genes, Chromosomes & Cancer, 2000, v. 27, n. 2, p. 209, doi. 10.1002/(SICI)1098-2264(200002)27:2<209::AID-GCC14>3.0.CO;2-U

By:

Pedeutour, Florence;
Quade, Bradley J.;
Sornberger, Kris;
Tallini, Giovanni;
Ligon, Azra H.;
Weremowicz, Stanislawa;
Morton, Cynthia C.

Publication type:

Article

Suppression of transformed phenotype and tumorigenicity after transfer of chromosome 4 into U251 human glioma cells.

Published in:

Genes, Chromosomes & Cancer, 1997, v. 20, n. 3, p. 260, doi. 10.1002/(SICI)1098-2264(199711)20:3<260::AID-GCC6>3.0.CO;2-0

By:

Pershouse, Mark A.;
Ligon, Azra H.;
Pereira-Smith, Olivia M.;
Killary, Ann M.;
Yung, W. K. Alfred;
Steck, Peter A.

Publication type:

Article

Potocki-Lupski syndrome: An inherited dup(17)(p11.2p11.2) with hypoplastic left heart.

Published in:

American Journal of Medical Genetics. Part A, 2011, v. 155A, n. 2, p. 367, doi. 10.1002/ajmg.a.33845

By:

Yusupov, Roman;
Roberts, Amy E.;
Lacro, Ronald V.;
Sandstrom, Mary;
Ligon, Azra H.

Publication type:

Article

DNA Fragmentation Simulation Method (FSM) and Fragment Size Matching Improve aCGH Performance of FFPE Tissues.

Published in:

PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0038881

By:

Craig, Justin M.;
Vena, Natalie;
Ramkissoon, Shakti;
Idbaih, Ahmed;
Fouse, Shaun D.;
Ozek, Memet;
Sav, Aydin;
Ashley Hill, D.;
Margraf, Linda R.;
Eberhart, Charles G.;
Kieran, Mark W.;
Norden, Andrew D.;
Wen, Patrick Y.;
Loda, Massimo;
Santagata, Sandro;
Ligon, Keith L.;
Ligon, Azra H.

Publication type:

Article

BRAF V600E Mutations Are Common in Pleomorphic Xanthoastrocytoma: Diagnostic and Therapeutic Implications.

Published in:

PLoS ONE, 2011, v. 6, n. 3, p. 1, doi. 10.1371/journal.pone.0017948

By:

Dias-Santagata, Dora;
Quynh Lam;
Vernovsky, Kathy;
Vena, Natalie;
Lennerz, Jochen K.;
Borger, Darrell R.;
Batchelor, Tracy T.;
Ligon, Keith L.;
Iafrate, A. John;
Ligon, Azra H.;
Louis, David N.;
Santagata, Sandro

Publication type:

Article

Chromosomal microarray analysis in pregnancy loss: Is it time for a consensus approach?

Published in:

Prenatal Diagnosis, 2022, v. 42, n. 12, p. 1545, doi. 10.1002/pd.6244

By:

Schilit, Samantha L. P.;
Studwell, Courtney;
Flatley, Pamela;
Listewnik, Marc;
Mertens, Lauren;
Ligon, Azra H.;
Mason‐Suares, Heather

Publication type:

Article

The landscape of somatic copy-number alteration across human cancers.

Published in:

Nature, 2010, v. 463, n. 7283, p. 899, doi. 10.1038/nature08822

By:

Beroukhim, Rameen;
Mermel, Craig H.;
Porter, Dale;
Wei, Guo;
Raychaudhuri, Soumya;
Donovan, Jerry;
Barretina, Jordi;
Boehm, Jesse S.;
Dobson, Jennifer;
Urashima, Mitsuyoshi;
Mc Henry, Kevin T.;
Pinchback, Reid M.;
Ligon, Azra H.;
Cho, Yoon-Jae;
Haery, Leila;
Greulich, Heidi;
Reich, Michael;
Winckler, Wendy;
Lawrence, Michael S.;
Weir, Barbara A.

Publication type:

Article

Molecular and clinicopathologic features of gliomas harboring NTRK fusions.

Published in:

Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-00980-z

By:

Torre, Matthew;
Vasudevaraja, Varshini;
Serrano, Jonathan;
DeLorenzo, Michael;
Malinowski, Seth;
Blandin, Anne-Florence;
Pages, Melanie;
Ligon, Azra H.;
Dong, Fei;
Meredith, David M.;
Nasrallah, MacLean P.;
Horbinski, Craig;
Dahiya, Sonika;
Ligon, Keith L.;
Santi, Mariarita;
Ramkissoon, Shakti H.;
Filbin, Mariella G.;
Snuderl, Matija;
Alexandrescu, Sanda

Publication type:

Article

LGG-02. A PHASE II PROSPECTIVE TRIAL OF SELUMETINIB IN CHILDREN WITH RECURRENT/PROGRESSIVE PEDIATRIC LOW-GRADE GLIOMA (PLGG) WITH A FOCUS UPON OPTIC PATHWAY/HYPOTHALAMIC TUMORS AND VISUAL ACUITY OUTCOMES: A PEDIATRIC BRAIN TUMOR CONSORTIUM (PBTC) STUDY, PBTC-029B

Published in:

Neuro-Oncology, 2019, v. 21, p. ii98, doi. 10.1093/neuonc/noz036.145

By:

Fangusaro, Jason;
Onar-Thomas, Arzu;
Poussaint, Tina Young;
Wu, Shengjie;
Ligon, Azra H;
Lindeman, Neal;
Banerjee, Anu;
Packer, Roger J;
Kilburn, Lindsay B;
Goldman, Stewart;
Pollack, Ian F;
Jakacki, Regina I;
Qaddoumi, Ibrahim;
Fisher, Paul G;
Dhall, Girish;
Baxter, Patricia;
Kreissman, Susa G;
Stewart, Clinton F;
Jones, David T W;
Pfister, Stefan M

Publication type:

Article

Leveraging molecular datasets for biomarker-based clinical trial design in glioblastoma.

Published in:

Neuro-Oncology, 2017, v. 19, n. 7, p. 908, doi. 10.1093/neuonc/now312

By:

Tanguturi, Shyam K.;
Trippa, Lorenzo;
Ramkissoon, Shakti H.;
Pelton, Kristine;
Knoff, David;
Sandak, David;
Lindeman, Neal I.;
Ligon, Azra H.;
Beroukhim, Rameen;
Parmigiani, Giovanni;
Wen, Patrick Y.;
Ligon, Keith L.;
Alexander, Brian M.

Publication type:

Article

Germline and somatic BAP1 mutations in high-grade rhabdoid meningiomas.

Published in:

Neuro-Oncology, 2017, v. 19, n. 4, p. 535, doi. 10.1093/neuonc/now235

By:

Shankar, Ganesh M.;
Abedalthagafi, Malak;
Vaubel, Rachael A.;
Merrill, Parker H.;
Nayyar, Naema;
Gill, Corey M.;
Brewster, Ryan;
Bi, Wenya Linda;
Agarwalla, Pankaj K.;
Thorner, Aaron R.;
Reardon, David A.;
Al-Mefty, Ossama;
Wen, Patrick Y.;
Alexander, Brian M.;
van Hummelen, Paul;
Batchelor, Tracy T.;
Ligon, Keith L.;
Ligon, Azra H.;
Meyerson, Matthew;
Dunn, Ian F.

Publication type:

Article

Oncogenic PI3K mutations are as common as AKT1 and SMO mutations in meningioma.

Published in:

Neuro-Oncology, 2016, v. 18, n. 5, p. 649, doi. 10.1093/neuonc/nov316

By:

Abedalthagafi, Malak;
Wenya Linda Bi;
Aizer, Ayal A.;
Merrill, Parker H.;
Brewster, Ryan;
Agarwalla, Pankaj K.;
Listewnik, Marc L.;
Dias-Santagata, Dora;
Thorner, Aaron R.;
Van Hummelen, Paul;
Brastianos, Priscilla K.;
Reardon, David A.;
Wen, Patrick Y.;
Al-Mefty, Ossama;
Ramkissoon, Shakti H.;
Folkerth, Rebecca D.;
Ligon, Keith L.;
Ligon, Azra H.;
Alexander, Brian M.;
Dunn, Ian F.

Publication type:

Article

A prognostic cytogenetic scoring system to guide the adjuvant management of patients with atypical meningioma.

Published in:

Neuro-Oncology, 2016, v. 18, n. 2, p. 269, doi. 10.1093/neuonc/nov177

By:

Aizer, Ayal A.;
Abedalthagafi, Malak;
Bi, Wenya Linda;
Horvath, Margaret C.;
Arvold, Nils D.;
Al-Mefty, Ossama;
Lee, Eudocia Q.;
Nayak, Lakshmi;
Rinne, Mikael L.;
Norden, Andrew D.;
Reardon, David A.;
Wen, Patrick Y.;
Ligon, Keith L.;
Ligon, Azra H.;
Beroukhim, Rameen;
Dunn, Ian F.;
Santagata, Sandro;
Alexander, Brian M.

Publication type:

Article

Expression profiles of 151 pediatric low-grade gliomas reveal molecular differences associated with location and histological subtype.

Published in:

Neuro-Oncology, 2015, v. 17, n. 11, p. 1486, doi. 10.1093/neuonc/nov045

By:

Bergthold, Guillaume;
Bandopadhayay, Pratiti;
Hoshida, Yujin;
Ramkissoon, Shakti;
Ramkissoon, Lori;
Rich, Benjamin;
Maire, Cecile L.;
Paolella, Brenton R.;
Schumacher, Steven E.;
Tabak, Barbara;
Ferrer-Luna, Ruben;
Ozek, Memet;
Sav, Aydin;
Santagata, Sandro;
Patrick Yung Wen;
Goumnerova, Liliana C.;
Ligon, Azra H.;
Stiles, Charles;
Segal, Rosalind;
Golub, Todd

Publication type:

Article

Phase I/II study of erlotinib and temsirolimus for patients with recurrent malignant gliomas: North American Brain Tumor Consortium trial 04-02.

Published in:

Neuro-Oncology, 2014, v. 16, n. 4, p. 567, doi. 10.1093/neuonc/not247

By:

Wen, Patrick Y.;
Chang, Susan M.;
Lamborn, Kathleen R.;
Kuhn, John G.;
Norden, Andrew D.;
Cloughesy, Timothy F.;
Robins, H. Ian;
Lieberman, Frank S.;
Gilbert, Mark R.;
Mehta, Minesh P.;
Drappatz, Jan;
Groves, Morris D.;
Santagata, Sandro;
Ligon, Azra H.;
Yung, W.K. Alfred;
Wright, John J.;
Dancey, Janet;
Aldape, Kenneth D.;
Prados, Michael D.;
Ligon, Keith L.

Publication type:

Article

Detection of ERBB2 Amplification by Next-Generation Sequencing Predicts HER2 Expression in Colorectal Carcinoma.

Published in:

2019

By:

Cenaj, Odise;
Ligon, Azra H;
Hornick, Jason L;
Sholl, Lynette M

Publication type:

journal article

Validation of OncoPanel: A Targeted Next-Generation Sequencing Assay for the Detection of Somatic Variants in Cancer.

Published in:

Archives of Pathology & Laboratory Medicine, 2017, v. 141, n. 6, p. 751, doi. 10.5858/arpa.2016-0527-OA

By:

Garcia, Elizabeth P.;
Minkovsky, Alissa;
Yonghui Jia;
Ducar, Matthew D.;
Shivdasani, Priyanka;
Xin Gong;
Ligon, Azra H.;
Sholl, Lynette M.;
Kuo, Frank C.;
MacConaill, Laura E.;
Lindeman, Neal I.;
Fei Dong

Publication type:

Article