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Therapy response testing of breast cancer in a 3D high-throughput perfused microfluidic platform.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Estimation and inference for the indirect effect in high-dimensional linear mediation models.
- Published in:
- Biometrika, 2020, v. 107, n. 3, p. 573, doi. 10.1093/biomet/asaa016
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- Publication type:
- Article
Pharmacogenomics: bench to bedside.
- Published in:
- Nature Reviews Drug Discovery, 2004, v. 3, n. 9, p. 739, doi. 10.1038/nrd1497
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- Publication type:
- Article
The novel function of tumor protein D54 in regulating pyruvate dehydrogenase and metformin cytotoxicity in breast cancer.
- Published in:
- Cancer & Metabolism, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40170-018-0193-4
- By:
- Publication type:
- Article
Multi-Omics Characterization of Early- and Adult-Onset Major Depressive Disorder.
- Published in:
- Journal of Personalized Medicine, 2022, v. 12, n. 3, p. 412, doi. 10.3390/jpm12030412
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- Publication type:
- Article
Testis- specific Y-encoded- like protein 1 and cholesterol metabolism: Regulation of CYP1B1 expression through Wnt signaling.
- Published in:
- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1047318
- By:
- Publication type:
- Article
Network science approach elucidates integrative genomic-metabolomic signature of antidepressant response and lifetime history of attempted suicide in adults with major depressive disorder.
- Published in:
- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.984383
- By:
- Publication type:
- Article
Measure transcript integrity using RNA-seq data.
- Published in:
- BMC Bioinformatics, 2016, v. 17, p. 1, doi. 10.1186/s12859-016-0922-z
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- Publication type:
- Article
Knowledge-guided analysis of "omics" data using the KnowEnG cloud platform.
- Published in:
- PLoS Biology, 2020, v. 18, n. 1, p. 1, doi. 10.1371/journal.pbio.3000583
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- Publication type:
- Article
4-Hydroxytamoxifen enhances sensitivity of estrogen receptor α-positive breast cancer to docetaxel in an estrogen and ZNF423 SNP-dependent fashion.
- Published in:
- Breast Cancer Research & Treatment, 2019, v. 175, n. 3, p. 567, doi. 10.1007/s10549-019-05194-z
- By:
- Publication type:
- Article
ATP-sensitive K<sup>+</sup> channel openers prevent Ca<sup>2+</sup> overload in rat cardiac mitochondria.
- Published in:
- Journal of Physiology, 1999, v. 519, n. 2, p. 347, doi. 10.1111/j.1469-7793.1999.0347m.x
- By:
- Publication type:
- Article
Blockade of tumor cell-intrinsic PD-L1 signaling enhances AURKA-targeted therapy in triple negative breast cancer.
- Published in:
- Frontiers in Oncology, 2024, p. 1, doi. 10.3389/fonc.2024.1384277
- By:
- Publication type:
- Article
Androgen receptor splice variants bind to constitutively open chromatin and promote abiraterone-resistant growth of prostate cancer.
- Published in:
- Nucleic Acids Research, 2018, v. 46, n. 4, p. 1895, doi. 10.1093/nar/gkx1306
- By:
- Publication type:
- Article
AMPK regulates histone H2B O-GlcNAcylation.
- Published in:
- Nucleic Acids Research, 2015, v. 43, n. 9, p. 5594, doi. 10.1093/nar/gku236
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- Publication type:
- Article
The eSNV-detect: a computational system to identify expressed single nucleotide variants from transcriptome sequencing data.
- Published in:
- Nucleic Acids Research, 2014, v. 42, n. 22, p. 1, doi. 10.1093/nar/gku1005
- By:
- Publication type:
- Article
AMPK regulates histone H2B O-GlcNAcylation.
- Published in:
- Nucleic Acids Research, 2014, v. 42, n. 9, p. 5594, doi. 10.1093/nar/gku236
- By:
- Publication type:
- Article
A noncanonical AR addiction drives enzalutamide resistance in prostate cancer.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21860-7
- By:
- Publication type:
- Article
SNPs near the cysteine proteinase cathepsin O gene (CTSO) determine tamoxifen sensitivity in ERα-positive breast cancer through regulation of BRCA1.
- Published in:
- PLoS Genetics, 2017, v. 13, n. 10, p. 1, doi. 10.1371/journal.pgen.1007031
- By:
- Publication type:
- Article
A network-based phenotype mapping approach to identify genes that modulate drug response phenotypes.
- Published in:
- Scientific Reports, 2016, p. 37003, doi. 10.1038/srep37003
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- Publication type:
- Article
NDUFA4L2 promotes trastuzumab resistance in HER2-positive breast cancer.
- Published in:
- Therapeutic Advances in Medical Oncology, 2021, p. 1, doi. 10.1177/17588359211027836
- By:
- Publication type:
- Article
NDUFA4L2 promotes trastuzumab resistance in HER2-positive breast cancer.
- Published in:
- Therapeutic Advances in Medical Oncology, 2021, p. 1, doi. 10.1177/17588359211027836
- By:
- Publication type:
- Article
Bora Downregulation Results in Radioresistance by Promoting Repair of Double Strand Breaks.
- Published in:
- PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0119208
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- Publication type:
- Article
Snail Contributes to the Maintenance of Stem Cell-Like Phenotype Cells in Human Pancreatic Cancer.
- Published in:
- PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0087409
- By:
- Publication type:
- Article
Contribution of <i>FKBP5</i> Genetic Variation to Gemcitabine Treatment and Survival in Pancreatic Adenocarcinoma.
- Published in:
- PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0070216
- By:
- Publication type:
- Article
Identifying the Genetic Variation of Gene Expression Using Gene Sets: Application of Novel Gene Set eQTL Approach to PharmGKB and KEGG.
- Published in:
- PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0043301
- By:
- Publication type:
- Article
FKBP5 as a Selection Biomarker for Gemcitabine and Akt Inhibitors in Treatment of Pancreatic Cancer.
- Published in:
- PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0036252
- By:
- Publication type:
- Article
Genetic Association Studies of Copy-Number Variation: Should Assignment of Copy Number States Precede Testing?
- Published in:
- PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0034262
- By:
- Publication type:
- Article
Pharmacogenetics: Inherited Variation in Amino Acid Sequence and Altered Protein Quantity<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 4, p. 253, doi. 10.1016/j.clpt.2003.12.002
- By:
- Publication type:
- Article
Human glucocorticoid receptor alpha gene (NR3C1) pharmacogenomics: gene resequencing and functional genomics.
- Published in:
- 2009
- By:
- Publication type:
- journal article
Differential roles of ERRFI1 in EGFR and AKT pathway regulation affect cancer proliferation.
- Published in:
- EMBO Reports, 2018, v. 19, n. 3, p. 1, doi. 10.15252/embr.201744767
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- Publication type:
- Article
Establishment and characterization of immortalized human breast cancer cell lines from breast cancer patient-derived xenografts (PDX).
- Published in:
- NPJ Breast Cancer, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41523-021-00285-x
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- Publication type:
- Article
Breast cancer chemoprevention pharmacogenomics: Deep sequencing and functional genomics of the ZNF423 and CTSO genes.
- Published in:
- NPJ Breast Cancer, 2017, v. 3, n. 1, p. N.PAG, doi. 10.1038/s41523-017-0036-4
- By:
- Publication type:
- Article
Multi-omics driven predictions of response to acute phase combination antidepressant therapy: a machine learning approach with cross-trial replication.
- Published in:
- Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01632-z
- By:
- Publication type:
- Article
Identification of genetic variants or genes that are associated with Homoharringtonine (HHT) response through a genome-wide association study in human lymphoblastoid cell lines (LCLs).
- Published in:
- Frontiers in Genetics, 2015, v. 5, p. 1, doi. 10.3389/fgene.2014.00465
- By:
- Publication type:
- Article
UFL1 promotes histone H4 ufmylation and ATM activation.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-09175-0
- By:
- Publication type:
- Article
Plasma Copy Number Alteration-Based Prognostic and Predictive Multi-Gene Risk Score in Metastatic Castration-Resistant Prostate Cancer.
- Published in:
- Cancers, 2022, v. 14, n. 19, p. 4714, doi. 10.3390/cancers14194714
- By:
- Publication type:
- Article
Identification of Src Family Kinases as Potential Therapeutic Targets for Chemotherapy-Resistant Triple Negative Breast Cancer.
- Published in:
- Cancers, 2022, v. 14, n. 17, p. 4220, doi. 10.3390/cancers14174220
- By:
- Publication type:
- Article
The lncRNA MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1.
- Published in:
- 2019
- By:
- Publication type:
- journal article
NOTCH3 expression is linked to breast cancer seeding and distant metastasis.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Calmodulin-like protein 3 is an estrogen receptor alpha coregulator for gene expression and drug response in a SNP, estrogen, and SERM-dependent fashion.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Use of the gamma method for self-contained gene-set analysis of SNP data.
- Published in:
- European Journal of Human Genetics, 2012, v. 20, n. 5, p. 565, doi. 10.1038/ejhg.2011.236
- By:
- Publication type:
- Article
Sumoylation of MDC1 is important for proper DNA damage response.
- Published in:
- EMBO Journal, 2012, v. 31, n. 13, p. 3008, doi. 10.1038/emboj.2012.158
- By:
- Publication type:
- Article
SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway.
- Published in:
- Breast Cancer Research & Treatment, 2017, v. 164, n. 1, p. 189, doi. 10.1007/s10549-017-4243-3
- By:
- Publication type:
- Article
A polygenic risk score for breast cancer in women receiving tamoxifen or raloxifene on NSABP P-1 and P-2.
- Published in:
- Breast Cancer Research & Treatment, 2015, v. 149, n. 2, p. 517, doi. 10.1007/s10549-014-3175-4
- By:
- Publication type:
- Article
MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites.
- Published in:
- Nature, 2011, v. 470, n. 7332, p. 124, doi. 10.1038/nature09658
- By:
- Publication type:
- Article
Tumor protein D52 (TPD52) affects cancer cell metabolism by negatively regulating AMPK.
- Published in:
- Cancer Medicine, 2023, v. 12, n. 1, p. 488, doi. 10.1002/cam4.4911
- By:
- Publication type:
- Article
Metabolomic signature of exposure and response to citalopram/escitalopram in depressed outpatients.
- Published in:
- Translational Psychiatry, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41398-019-0507-5
- By:
- Publication type:
- Article
Toward Individualized Prediction of Response to Methotrexate in Early Rheumatoid Arthritis: A Pharmacogenomics‐Driven Machine Learning Approach.
- Published in:
- Arthritis Care & Research, 2022, v. 74, n. 6, p. 879, doi. 10.1002/acr.24834
- By:
- Publication type:
- Article
Aromatase inhibitors, estrogens and musculoskeletal pain: estrogen-dependent T-cell leukemia 1A (TCL1A) gene-mediated regulation of cytokine expression.
- Published in:
- 2012
- By:
- Publication type:
- journal article
Comparing outcomes and costs among warfarin-sensitive patients versus warfarin-insensitive patients using The Right Drug, Right Dose, Right Time: Using genomic data to individualize treatment (RIGHT) 10K warfarin cohort.
- Published in:
- PLoS ONE, 2020, v. 15, n. 5, p. 1, doi. 10.1371/journal.pone.0233316
- By:
- Publication type:
- Article