Works by Lieberman, Paul M.

Results: 62

Epigenetic Control of Replication Origins.

Published in:

Cell Cycle, 2005, v. 4, n. 7, p. 889, doi. 10.4161/cc.4.7.1823

By:

Jing Zhou;
Chau, Charles;
Zhong Deng;
Stedman, William;
Lieberman, Paul M.

Publication type:

Article

A role for CTCF and cohesin in subtelomere chromatin organization, TERRA transcription, and telomere end protection.

Published in:

EMBO Journal, 2012, v. 31, n. 21, p. 4165, doi. 10.1038/emboj.2012.266

By:

Deng, Zhong;
Wang, Zhuo;
Stong, Nick;
Plasschaert, Robert;
Moczan, Aliah;
Chen, Horng-Shen;
Hu, Sufeng;
Wikramasinghe, Priyankara;
Davuluri, Ramana V;
Bartolomei, Marisa S;
Riethman, Harold;
Lieberman, Paul M

Publication type:

Article

RNA-dependent recruitment of the origin recognition complex.

Published in:

EMBO Journal, 2008, v. 27, n. 22, p. 3024, doi. 10.1038/emboj.2008.221

By:

Norseen, Julie;
Thomae, Andreas;
Sridharan, Venkatesh;
Aiyar, Ashok;
Schepers, Aloys;
Lieberman, Paul M

Publication type:

Article

Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators.

Published in:

EMBO Journal, 2008, v. 27, n. 4, p. 654, doi. 10.1038/emboj.2008.1

By:

Stedman, William;
Hyojeung Kang;
Shu Lin;
Kissil, Joseph L.;
Bartolomei, Marisa S.;
Lieberman, Paul M.

Publication type:

Article

Cell cycle regulation of chromatin at an origin of DNA replication.

Published in:

EMBO Journal, 2005, v. 24, n. 7, p. 1406, doi. 10.1038/sj.emboj.7600609

By:

Jing Zhou;
Chau, Charles M;
Zhong Deng;
Shiekhattar, Ramin;
Spindler, Mark-Peter;
Schepers, Aloys;
Lieberman, Paul M

Publication type:

Article

EBNA2 driven enhancer switching at the CIITA-DEXI locus suppresses HLA class II gene expression during EBV infection of B-lymphocytes.

Published in:

PLoS Pathogens, 2021, v. 17, n. 8, p. 1, doi. 10.1371/journal.ppat.1009834

By:

Su, Chenhe;
Lu, Fang;
Soldan, Samantha S.;
Lamontagne, R. Jason;
Tang, Hsin-Yao;
Napoletani, Giorgia;
Farrell, Paul J.;
Tempera, Italo;
Kossenkov, Andrew V.;
Lieberman, Paul M.

Publication type:

Article

Keeping it quiet: chromatin control of gammaherpesvirus latency.

Published in:

Nature Reviews Microbiology, 2013, v. 11, n. 12, p. 863, doi. 10.1038/nrmicro3135

By:

Lieberman, Paul M.

Publication type:

Article

Biophysical Screens Identify Fragments That Bind to the Viral DNA-Binding Proteins EBNA1 and LANA.

Published in:

Molecules, 2020, v. 25, n. 7, p. 1760, doi. 10.3390/molecules25071760

By:

Messick, Troy E.;
Tolvinski, Lois;
Zartler, Edward R.;
Moberg, Anna;
Frostell, Åsa;
Smith, Garry R.;
Reitz, Allen B.;
Lieberman, Paul M.;
Stockman, Brian J.

Publication type:

Article

Author Correction: CTCF interacts with the lytic HSV-1 genome to promote viral transcription.

Published in:

2021

By:

Lang, Fengchao;
Li, Xin;
Vladimirova, Olga;
Hu, Benxia;
Chen, Guijun;
Xiao, Yu;
Singh, Vikrant;
Lu, Danfeng;
Li, Lihong;
Han, Hongbo;
Wickramasinghe, J. M. A. S. P.;
Smith, Sheryl T.;
Zheng, Chunfu;
Li, Qihan;
Lieberman, Paul M.;
Fraser, Nigel W.;
Zhou, Jumin

Publication type:

Correction Notice

TERRA G-quadruplex RNA interaction with TRF2 GAR domain is required for telomere integrity.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-82406-x

By:

Mei, Yang;
Deng, Zhong;
Vladimirova, Olga;
Gulve, Nitish;
Johnson, F. Brad;
Drosopoulos, William C.;
Schildkraut, Carl L.;
Lieberman, Paul M.

Publication type:

Article

CTCF driven TERRA transcription facilitates completion of telomere DNA replication.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-02212-w

By:

Beishline, Kate;
Vladimirova, Olga;
Tutton, Stephen;
Zhuo Wang;
Zhong Deng;
Lieberman, Paul M.

Publication type:

Article

ATRX loss induces telomere dysfunction and necessitates induction of alternative lengthening of telomeres during human cell immortalization.

Published in:

EMBO Journal, 2019, v. 38, n. 19, p. N.PAG, doi. 10.15252/embj.201796659

By:

Li, Fei;
Deng, Zhong;
Zhang, Ling;
Wu, Caizhi;
Jin, Ying;
Hwang, Inah;
Vladimirova, Olga;
Xu, Libo;
Yang, Lynnie;
Lu, Bin;
Dheekollu, Javaraju;
Li, Jian‐Yi;
Feng, Hua;
Hu, Jian;
Vakoc, Christopher R;
Ying, Haoqiang;
Paik, Jihye;
Lieberman, Paul M;
Zheng, Hongwu

Publication type:

Article

Subtelomeric p53 binding prevents accumulation of DNA damage at human telomeres.

Published in:

EMBO Journal, 2016, v. 35, n. 2, p. 193, doi. 10.15252/embj.201490880

By:

Tutton, Stephen;
Azzam, Greggory A;
Stong, Nicholas;
Vladimirova, Olga;
Wiedmer, Andreas;
Monteith, Jessica A;
Beishline, Kate;
Wang, Zhuo;
Deng, Zhong;
Riethman, Harold;
McMahon, Steven B;
Murphy, Maureen;
Lieberman, Paul M

Publication type:

Article

Getting Back to the Basics of Translational Research.

Published in:

PLoS Pathogens, 2016, v. 12, n. 7, p. 1, doi. 10.1371/journal.ppat.1005534

By:

Lieberman, Paul M.

Publication type:

Article

EBNA2 Drives Formation of New Chromosome Binding Sites and Target Genes for B-Cell Master Regulatory Transcription Factors RBP-jκ and EBF1.

Published in:

PLoS Pathogens, 2016, v. 12, n. 1, p. 1, doi. 10.1371/journal.ppat.1005339

By:

Lu, Fang;
Chen, Horng-Shen;
Kossenkov, Andrew V.;
DeWispeleare, Karen;
Won, Kyoung-Jae;
Lieberman, Paul M.

Publication type:

Article

Identification of Small-Molecule PHD2 Zinc Finger Inhibitors that Activate Hypoxia Inducible Factor.

Published in:

ChemBioChem, 2016, v. 17, n. 24, p. 2316, doi. 10.1002/cbic.201600493

By:

Arsenault, Patrick R.;
Song, Daisheng;
Bergkamp, Marian;
Ravaschiere, Andrew M.;
Navalsky, Bradleigh E.;
Lieberman, Paul M.;
Lee, Frank S.

Publication type:

Article

Chromatin organization and virus gene expression.

Published in:

Journal of Cellular Physiology, 2008, v. 216, n. 2, p. 295, doi. 10.1002/jcp.21421

By:

Lieberman, Paul M.

Publication type:

Article

ORC binding to TRF2 stimulates OriP replication.

Published in:

EMBO Reports, 2006, v. 7, n. 7, p. 716, doi. 10.1038/sj.embor.7400730

By:

Atanasiu, Constandache;
Zhong Deng;
Wiedmer, Andreas;
Norseen, Julie;
Lieberman, Paul M.

Publication type:

Article

Epigenetic Plasticity Enables CNS-Trafficking of EBV-infected B Lymphocytes.

Published in:

PLoS Pathogens, 2021, v. 17, n. 6, p. 1, doi. 10.1371/journal.ppat.1009618

By:

Soldan, Samantha S.;
Su, Chenhe;
Lamontagne, R. Jason;
Grams, Nicholas;
Lu, Fang;
Zhang, Yue;
Gesualdi, James D.;
Frase, Drew M.;
Tolvinski, Lois E.;
Martin, Kayla;
Messick, Troy E.;
Fingerut, Jonathan T.;
Koltsova, Ekaterina;
Kossenkov, Andrew;
Lieberman, Paul M.

Publication type:

Article

A multi-omics approach to Epstein-Barr virus immortalization of B-cells reveals EBNA1 chromatin pioneering activities targeting nucleotide metabolism.

Published in:

PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009208

By:

Lamontagne, R. Jason;
Soldan, Samantha S.;
Su, Chenhe;
Wiedmer, Andreas;
Won, Kyoung Jae;
Lu, Fang;
Goldman, Aaron R.;
Wickramasinghe, Jayamanna;
Tang, Hsin-Yao;
Speicher, David W.;
Showe, Louise;
Kossenkov, Andrew V.;
Lieberman, Paul M.

Publication type:

Article

Phase separation and DAXX redistribution contribute to LANA nuclear body and KSHV genome dynamics during latency and reactivation.

Published in:

PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009231

By:

Vladimirova, Olga;
De Leo, Alessandra;
Deng, Zhong;
Wiedmer, Andreas;
Hayden, James;
Lieberman, Paul M.

Publication type:

Article

Comparative transcriptome analysis of endemic and epidemic Kaposi's sarcoma (KS) lesions and the secondary role of HIV-1 in KS pathogenesis.

Published in:

PLoS Pathogens, 2020, v. 16, n. 7, p. 1, doi. 10.1371/journal.ppat.1008681

By:

Lidenge, Salum J.;
Kossenkov, Andrew V.;
Tso, For Yue;
Wickramasinghe, Jayamanna;
Privatt, Sara R.;
Ngalamika, Owen;
Ngowi, John R.;
Mwaiselage, Julius;
Lieberman, Paul M.;
West, John T.;
Wood, Charles

Publication type:

Article

ARID1A promotes genomic stability through protecting telomere cohesion.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12037-4

By:

Zhao, Bo;
Lin, Jianhuang;
Rong, Lijie;
Wu, Shuai;
Deng, Zhong;
Fatkhutdinov, Nail;
Zundell, Joseph;
Fukumoto, Takeshi;
Liu, Qin;
Kossenkov, Andrew;
Jean, Stephanie;
Cadungog, Mark G.;
Borowsky, Mark E.;
Drapkin, Ronny;
Lieberman, Paul M.;
Abate-Shen, Cory T.;
Zhang, Rugang

Publication type:

Article

Retrotransposon-derived p53 binding sites enhance telomere maintenance and genome protection.

Published in:

BioEssays, 2016, v. 38, n. 10, p. 943, doi. 10.1002/bies.201600078

By:

Lieberman, Paul M.

Publication type:

Article

LANA oligomeric architecture is essential for KSHV nuclear body formation and viral genome maintenance during latency.

Published in:

PLoS Pathogens, 2019, v. 15, n. 1, p. 1, doi. 10.1371/journal.ppat.1007489

By:

De Leo, Alessandra;
Deng, Zhong;
Vladimirova, Olga;
Chen, Horng-Shen;
Dheekollu, Jayaraju;
Calderon, Abram;
Myers, Kenneth A.;
Hayden, James;
Keeney, Frederick;
Kaufer, Benedikt B.;
Yuan, Yan;
Robertson, Erle;
Lieberman, Paul M.

Publication type:

Article

EBNA1 inhibitors have potent and selective antitumor activity in xenograft models of Epstein–Barr virus-associated gastric cancer.

Published in:

Gastric Cancer, 2021, v. 24, n. 5, p. 1076, doi. 10.1007/s10120-021-01193-6

By:

Soldan, Samantha S.;
Anderson, Emma M.;
Frase, Drew M.;
Zhang, Yue;
Caruso, Lisa B.;
Wang, Yin;
Deakyne, Julianna S.;
Gewurz, Benjamin E.;
Tempera, Italo;
Lieberman, Paul M.;
Messick, Troy E.

Publication type:

Article

Telomeres and viruses: common themes of genome maintenance.

Published in:

Frontiers in Oncology, 2012, v. 2, p. 1, doi. 10.3389/fonc.2012.00201

By:

Zhong Deng;
Zhuo Wang;
Lieberman, Paul M.

Publication type:

Article

Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth.

Published in:

Science Translational Medicine, 2019, v. 11, n. 482, p. N.PAG, doi. 10.1126/scitranslmed.aau5612

By:

Messick, Troy E.;
Smith, Garry R.;
Soldan, Samantha S.;
McDonnell, Mark E.;
Deakyne, Julianna S.;
Malecka, Kimberly A.;
Tolvinski, Lois;
van den Heuvel, A. Pieter J.;
Gu, Bai-Wei;
Cassel, Joel A.;
Tran, Donna H.;
Wassermann, Benjamin R.;
Zhang, Yan;
Velvadapu, Venkata;
Zartler, Edward R.;
Busson, Pierre;
Reitz, Allen B.;
Lieberman, Paul M.

Publication type:

Article

TERRA and the histone methyltransferase Dot1 cooperate to regulate senescence in budding yeast.

Published in:

PLoS ONE, 2018, v. 13, n. 4, p. 1, doi. 10.1371/journal.pone.0195698

By:

Wanat, Jennifer J.;
Logsdon, Glennis A.;
Driskill, Jordan H.;
Deng, Zhong;
Lieberman, Paul M.;
Johnson, F. Brad

Publication type:

Article

Viral remodeling of the 4D nucleome.

Published in:

Experimental & Molecular Medicine EMM, 2024, v. 56, n. 4, p. 799, doi. 10.1038/s12276-024-01207-0

By:

Kim, Kyoung-Dong;
Lieberman, Paul M.

Publication type:

Article

The crosstalk of telomere dysfunction and inflammation through cell-free TERRA containing exosomes.

Published in:

RNA Biology, 2016, v. 13, n. 8, p. 690, doi. 10.1080/15476286.2016.1203503

By:

Wang, Zhuo;
Lieberman, Paul M.

Publication type:

Article

Structural and functional analysis of an OB-fold in human Ctc1 implicated in telomere maintenance and bone marrow syndromes.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 2, p. 972, doi. 10.1093/nar/gkx1213

By:

Shastrula, Prashanth K;
Rice, Cory T;
Wang, Zhuo;
Lieberman, Paul M;
Skordalakes, Emmanuel

Publication type:

Article

CTCF binding site sequence differences are associated with unique regulatory and functional trends during embryonic stem cell differentiation.

Published in:

Nucleic Acids Research, 2014, v. 42, n. 11, p. 7487, doi. 10.1093/nar/gku470

By:

Plasschaert, Robert N.;
Vigneau, Sébastien;
Tempera, Italo;
Gupta, Ravi;
Maksimoska, Jasna;
Everett, Logan;
Davuluri, Ramana;
Marmorstein, Ronen;
Lieberman, Paul M.;
Schultz, David;
Hannenhalli, Sridhar;
Bartolomei, Marisa S.

Publication type:

Article

CTCF binding site sequence differences are associated with unique regulatory and functional trends during embryonic stem cell differentiation.

Published in:

Nucleic Acids Research, 2014, v. 42, n. 2, p. 774, doi. 10.1093/nar/gkt910

By:

Plasschaert, Robert N.;
Vigneau, Sébastien;
Tempera, Italo;
Gupta, Ravi;
Maksimoska, Jasna;
Everett, Logan;
Davuluri, Ramana;
Mamorstein, Ronen;
Lieberman, Paul M.;
Schultz, David;
Hannenhalli, Sridhar;
Bartolomei, Marisa S.

Publication type:

Article

Structural basis underlying viral hijacking of a histone chaperone complex.

Published in:

Nature Communications, 2016, v. 7, n. 9, p. 12707, doi. 10.1038/ncomms12707

By:

Huang, Hongda;
Deng, Zhong;
Vladimirova, Olga;
Wiedmer, Andreas;
Lu, Fang;
Lieberman, Paul M.;
Patel, Dinshaw J.

Publication type:

Article

Interpreting the Epstein-Barr Virus (EBV) Epigenome Using High-Throughput Data.

Published in:

Viruses (1999-4915), 2013, v. 5, n. 4, p. 1042, doi. 10.3390/v5041042

By:

Arvey, Aaron;
Tempera, Italo;
Lieberman, Paul M.

Publication type:

Article

EBNA1 Binding and epigenetic regulation of gastrokine tumor suppressor genes in gastric carcinoma cells.

Published in:

Virology Journal, 2014, v. 11, n. 1, p. 1, doi. 10.1186/1743-422X-11-12

By:

Fang Lu;
Tempera, Italo;
Lee, Hyunna T.;
DeWispelaere, Karen;
Lieberman, Paul M.

Publication type:

Article

Genome-wide analysis of host-chromosome binding sites for Epstein-Barr Virus Nuclear Antigen 1 (EBNA1).

Published in:

Virology Journal, 2010, v. 7, p. 262, doi. 10.1186/1743-422X-7-262

By:

Fang Lu;
Wikramasinghe, Priyankara;
Norseen, Julie;
Tsai, Kevin;
Pu Wang;
Showe, Louise;
Davuluri, Ramana V.;
Lieberman, Paul M.

Publication type:

Article

Molecular Basis for Oligomeric-DNA Binding and Episome Maintenance by KSHV LANA.

Published in:

PLoS Pathogens, 2013, v. 9, n. 10, p. 1, doi. 10.1371/journal.ppat.1003672

By:

Domsic, John F.;
Chen, Horng-Shen;
Lu, Fang;
Marmorstein, Ronen;
Lieberman, Paul M.

Publication type:

Article

EBV Tegument Protein BNRF1 Disrupts DAXX-ATRX to Activate Viral Early Gene Transcription.

Published in:

PLoS Pathogens, 2011, v. 7, n. 11, p. 1, doi. 10.1371/journal.ppat.1002376

By:

Tsai, Kevin;
Thikmyanova, Nadezhda;
Wojcechowskyj, Jason A.;
Delecluse, Henri-Jacques;
Lieberman, Paul M.

Publication type:

Article

Coordination of KSHV Latent and Lytic Gene Control by CTCF-Cohesin Mediated Chromosome Conformation.

Published in:

PLoS Pathogens, 2011, v. 7, n. 8, p. 1, doi. 10.1371/journal.ppat.1002140

By:

Kang, Hyojeung;
Wiedmer, Andreas;
Yuan, Yan;
Robertson, Erle;
Lieberman, Paul M.

Publication type:

Article

EBV Latency Types Adopt Alternative Chromatin Conformations.

Published in:

PLoS Pathogens, 2011, v. 7, n. 7, p. 1, doi. 10.1371/journal.ppat.1002180

By:

Tempera, Italo;
Klichinsky, Michael;
Lieberman, Paul M.

Publication type:

Article

CTCF interacts with the lytic HSV-1 genome to promote viral transcription.

Published in:

Scientific Reports, 2017, p. 39861, doi. 10.1038/srep39861

By:

Lang, Fengchao;
Li, Xin;
Vladimirova, Olga;
Hu, Benxia;
Chen, Guijun;
Xiao, Yu;
Singh, Vikrant;
Lu, Danfeng;
Li, Lihong;
Han, Hongbo;
Wickramasinghe, J. M. A. S. P.;
Smith, Sheryl T.;
Zheng, Chunfu;
Li, Qihan;
Lieberman, Paul M.;
Fraser, Nigel W.;
Zhou, Jumin

Publication type:

Article

Epigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-019-14152-8

By:

Kim, Kyoung-Dong;
Tanizawa, Hideki;
De Leo, Alessandra;
Vladimirova, Olga;
Kossenkov, Andrew;
Lu, Fang;
Showe, Louise C.;
Noma, Ken-ichi;
Lieberman, Paul M.

Publication type:

Article

The Telomeric Response to Viral Infection.

Published in:

Viruses (1999-4915), 2017, v. 9, n. 8, p. 218, doi. 10.3390/v9080218

By:

Zhuo Wang;
Zhong Deng;
Tutton, Steve;
Lieberman, Paul M.

Publication type:

Article

Timeless Links Replication Termination to Mitotic Kinase Activation.

Published in:

PLoS ONE, 2011, v. 6, n. 5, p. 1, doi. 10.1371/journal.pone.0019596

By:

Dheekollu, Jayaraju;
Wiedmer, Andreas;
Hayden, James;
Speicher, David;
Gotter, Anthony L.;
Tim Yen;
Lieberman, Paul M.

Publication type:

Article

Discovery of Selective Inhibitors Against EBNA1 via High Throughput In Silico Virtual Screening.

Published in:

PLoS ONE, 2010, v. 5, n. 4, p. 1, doi. 10.1371/journal.pone.0010126

By:

Ning Li;
Thompson, Scott;
Schultz, David C.;
Weiliang Zhu;
Hualiang Jiang;
Cheng Luo;
Lieberman, Paul M.

Publication type:

Article

The three-dimensional structure of Epstein-Barr virus genome varies by latency type and is regulated by PARP1 enzymatic activity.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-021-27894-1

By:

Morgan, Sarah M.;
Tanizawa, Hideki;
Caruso, Lisa Beatrice;
Hulse, Michael;
Kossenkov, Andrew;
Madzo, Jozef;
Keith, Kelsey;
Tan, Yinfei;
Boyle, Sarah;
Lieberman, Paul M.;
Tempera, Italo

Publication type:

Article

DAXX-ATRX regulation of p53 chromatin binding and DNA damage response.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32680-8

By:

Gulve, Nitish;
Su, Chenhe;
Deng, Zhong;
Soldan, Samantha S.;
Vladimirova, Olga;
Wickramasinghe, Jayamanna;
Zheng, Hongwu;
Kossenkov, Andrew V.;
Lieberman, Paul. M.

Publication type:

Article

Correction: Deregulation of KSHV latency conformation by ER-stress and caspase-dependent RAD21-cleavage.

Published in:

2018

By:

De Leo, Alessandra;
Chen, Horng-Shen;
Hu, Chih-Chi Andrew;
Lieberman, Paul M.

Publication type:

Correction Notice