Works by Liangren Zhang

Results: 63

Rational Design and Identification of Small‐Molecule Allosteric Inhibitors of CD38.

Published in:

ChemBioChem, 2019, v. 20, n. 19, p. 2485, doi. 10.1002/cbic.201900169

By:

Yang, Lixin;
Li, Ting;
Li, Songlu;
Wu, Yang;
Shi, Xiaomeng;
Jin, Hongwei;
Liu, Zhenming;
Zhao, Yongjuan;
Zhang, Liangren;
Lee, Hon Cheung;
Zhang, Lihe

Publication type:

Article

Calcium‐Mobilizing Behaviors of Neutral Cyclic ADP‐Ribose Mimics that Integrate Modifications to the Nucleobase, Northern Ribose and Pyrophosphate.

Published in:

ChemBioChem, 2018, v. 19, n. 13, p. 1444, doi. 10.1002/cbic.201800133

By:

Wang, Xuan;
Zhang, Xiaoyan;
Zhang, Kehui;
Hu, Jianxing;
Liu, Zhenming;
Jin, Hongwei;
Zhang, Liangren;
Zhang, Lihe

Publication type:

Article

Copper-Catalyzed Aerobic Oxidative Coupling of Aryl Acetaldehydes with Anilines Leading to α-Ketoamides.

Published in:

Angewandte Chemie, 2011, v. 123, n. 47, p. 11284, doi. 10.1002/ange.201105285

By:

Zhang, Chun;
Xu, Zejun;
Zhang, Liangren;
Jiao, Ning

Publication type:

Article

Discovery of potential xanthine oxidase inhibitors based on virtual screening.

Published in:

Journal of Chinese Pharmaceutical Sciences, 2023, v. 32, n. 8, p. 626, doi. 10.5246/jcps.2023.08.052

By:

Xiaowei Chi;
Qi Li;
Yi Zhong;
Tong Gong;
Chuxiao Yi;
Liangren Zhang;
Zhenming Liu

Publication type:

Article

Challenging Reverse Screening: A Benchmark Study for Comprehensive Evaluation.

Published in:

Molecular Informatics, 2022, v. 41, n. 4, p. 1, doi. 10.1002/minf.202100063

By:

Li, Mingna;
Hu, Jianxing;
Wang, Yanxing;
Li, Yibo;
Zhang, Liangren;
Liu, Zhenming

Publication type:

Article

Privileged Scaffold Analysis of Natural Products with Deep Learning-based Indication Prediction Model.

Published in:

Molecular Informatics, 2020, v. 39, n. 11, p. 1, doi. 10.1002/minf.202000057

By:

Junyong Lai;
Jianxing Hu;
Yanxing Wang;
Xin Zhou;
Yibo Li;
Liangren Zhang;
Zhenming Liu

Publication type:

Article

Late Bronze Age metallurgy in Rudnyi Altai.

Published in:

Archaeological & Anthropological Sciences, 2022, v. 14, n. 8, p. 1, doi. 10.1007/s12520-022-01607-1

By:

Ma, Renjie;
Zhang, Liangren;
Cui, Jianfeng;
Tishkin, Alexey A.;
Grushin, Sergei P.;
Vertman, Evgenii G.;
Chang, Dongxue;
Hu, Di

Publication type:

Article

Cyclic Adenosine 5′-Diphosphoribose (c ADPR) Mimics Used as Molecular Probes in Cell Signaling.

Published in:

Chemical Record, 2015, v. 15, n. 2, p. 511, doi. 10.1002/tcr.201402072

By:

Zhang, Liangren;
Yue, Jianbo;
Zhang, Li‐He

Publication type:

Article

Analysis of LncRNA expression in cell differentiation.

Published in:

RNA Biology, 2018, v. 15, n. 3, p. 413, doi. 10.1080/15476286.2018.1441665

By:

Yang, Qin;
Wan, Qi;
Zhang, Letian;
Li, Yibo;
Zhang, Pei;
Li, Dong;
Feng, Chao;
Yi, Fan;
Zhang, Liangren;
Ding, Xianfeng;
Li, Hua;
Du, Quan

Publication type:

Article

Covalent complexes of proteasome model with peptide aldehyde inhibitors MG132 and MG101: docking and molecular dynamics study.

Published in:

Journal of Molecular Modeling, 2009, v. 15, n. 12, p. 1481, doi. 10.1007/s00894-009-0515-0

By:

Siwei Zhang;
Yawei Shi;
Hongwei Jin;
Zhenming Liu;
Liangren Zhang;
Lihe Zhang

Publication type:

Article

Discovery and antibacterial study of potential PPK1 inhibitors against uropathogenic E. coli.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 1224, doi. 10.1080/14756366.2020.1766453

By:

Peng, Liang;
Zeng, Liting;
Jin, Hongwei;
Yang, Lixin;
Xiao, Yi;
Lan, Ziquan;
Yu, Zhanpeng;
Ouyang, Shi;
Zhang, Liangren;
Sun, Ning

Publication type:

Article

Structural basis for the specific interaction of chicken haemoglobin with bromophenol blue: a computational analysis.

Published in:

Molecular Physics, 2010, v. 108, n. 2, p. 215, doi. 10.1080/00268971003623393

By:

Hui Yu;
Zhanli Wang;
Wenbin Qin;
Liangren Zhang

Publication type:

Article

The scoring bias in reverse docking and the score normalization strategy to improve success rate of target fishing.

Published in:

PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0171433

By:

Luo, Qiyao;
Zhao, Liang;
Hu, Jianxing;
Jin, Hongwei;
Liu, Zhenming;
Zhang, Liangren

Publication type:

Article

Copper-Catalyzed Aerobic Oxidative Coupling of Aryl Acetaldehydes with Anilines Leading to α-Ketoamides.

Published in:

Angewandte Chemie International Edition, 2011, v. 50, n. 47, p. 11088, doi. 10.1002/anie.201105285

By:

Zhang, Chun;
Xu, Zejun;
Zhang, Liangren;
Jiao, Ning

Publication type:

Article

Direct Transformation of Methyl Arenes to Aryl Nitriles at Room Temperature.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 38, p. 7094, doi. 10.1002/anie.200903838

By:

Zhou, Wang;
Zhang, Liangren;
Jiao, Ning

Publication type:

Article

Ligand-Free Pd-Catalyzed Highly Selective Arylation of Allylic Esters with Retention of the Traditional Leaving Group.

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 25, p. 4729, doi. 10.1002/anie.200800966

By:

Pan, Delin;
Chen, Anjun;
Su, Yijin;
Zhou, Wang;
Li, Si;
Jia, Wei;
Xiao, Juan;
Liu, Qingjian;
Zhang, Liangren;
Jiao, Ning

Publication type:

Article

Target Prediction Model for Natural Products Using Transfer Learning.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4632, doi. 10.3390/ijms22094632

By:

Qiang, Bo;
Lai, Junyong;
Jin, Hongwei;
Zhang, Liangren;
Liu, Zhenming;
Kirchmair, Johannes

Publication type:

Article

Binding Mode Prediction of Evodiamine within Vanilloid Receptor TRPV1.

Published in:

International Journal of Molecular Sciences, 2012, v. 13, n. 7, p. 8958, doi. 10.3390/ijms13078958

By:

Zhanli Wang;
Lidan Sun;
Hui Yu;
Yanhui Zhang;
Wuzhuang Gong;
Hongwei Jin;
Liangren Zhang;
Huaping Liang

Publication type:

Article

A pair of new elemanolide sesquiterpene lactones from Elephantopus scaber L.

Published in:

2017

By:

Guo, Yan;
Li, Meng;
Chen, Peng;
Wu, Qiong;
Gao, Chun;
Lu, Yuxuan;
Zhang, Liangren;
Yuan, Dan;
Fu, Hongzheng

Publication type:

Other

Computational investigation of interactions between Cdc37 and celastrol.

Published in:

Molecular Simulation, 2013, v. 39, n. 4, p. 270, doi. 10.1080/08927022.2012.718439

By:

Duan, Yaokai;
Jin, Hongwei;
Yu, Hui;
Wang, Zhanli;
Zhang, Liangren;
Huo, Jianxin

Publication type:

Article

Advances in Molecular Mechanisms for Traditional Chinese Medicine Actions in Regulating Tumor Immune Responses.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.01009

By:

Huang, Han;
Fang, Jiansong;
Fan, Xiude;
Miyata, Tatsunori;
Hu, Xiaoyue;
Zhang, Lihe;
Zhang, Liangren;
Cui, Yimin;
Liu, Zhenming;
Wu, Xiaoqin

Publication type:

Article

Interregional and intraregional interaction of the Tianshanbeilu population in eastern Xinjiang from the perspective of pottery analysis.

Published in:

Heritage Science, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40494-023-01096-y

By:

Zeng, Baodong;
Ma, Tao;
Wang, Yongqiang;
Zhang, Jie;
Zhang, Liangren;
Chang, Xi'en

Publication type:

Article

Koryŏ inlay celadon from Taicang Port of the Yuan Dynasty, China.

Published in:

Heritage Science, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40494-023-01089-x

By:

Chang, Dongxue;
Zhang, Zhiqing;
Li, Xiaoshuang;
Zhang, Liangren

Publication type:

Article

International trade of lead for glazed tile production in ancient East Asia.

Published in:

Archaeometry, 2024, v. 66, n. 1, p. 160, doi. 10.1111/arcm.12874

By:

Chang, Dongxue;
Cui, Jianfeng;
Song, Yubin;
Zhao, Zhefu;
Quan, Renxue;
Zhang, Liangren

Publication type:

Article

A scientific study of late Islamic blue‐white stonepaste wares of Iran.

Published in:

Archaeometry, 2022, v. 64, n. 5, p. 1110, doi. 10.1111/arcm.12765

By:

Ma, Yanying;
Li, Zhimin;
Zhang, Liangren;
Wu, Jingwei;
Xiong, Yingfei;
Vahdati, Ali;
Zhang, Jiayang

Publication type:

Article

Discovery of novel multidrug resistance protein 4 (MRP4) inhibitors as active agents reducing resistance to anticancer drug 6-Mercaptopurine (6-MP) by structure and ligand-based virtual screening.

Published in:

PLoS ONE, 2018, v. 13, n. 10, p. 1, doi. 10.1371/journal.pone.0205175

By:

Chen, Ya;
Yuan, Xia;
Xiao, Zhangping;
Jin, Hongwei;
Zhang, Liangren;
Liu, Zhenming

Publication type:

Article

Unfolding and Conformational Variations of Thrombin-Binding DNA Aptamers: Synthesis, Circular Dichroism and Molecular Dynamics Simulations.

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 993, doi. 10.1002/cmdc.201300564

By:

Sun, Lidan;
Jin, Hongwei;
Zhao, Xiaoyang;
Liu, Zhenming;
Guan, Yifu;
Yang, Zhenjun;
Zhang, Liangren;
Zhang, Lihe

Publication type:

Article

Design, Synthesis and Biological Evaluation of Noncovalent Inhibitors of Human CD38 NADase.

Published in:

ChemMedChem, 2012, v. 7, n. 2, p. 223, doi. 10.1002/cmdc.201100487

By:

Zhou, Yi;
Ting, Kai Yiu;
Lam, Connie Mo Ching;
Kwong, Anna Ka Yee;
Xia, Jie;
Jin, Hongwei;
Liu, Zhenming;
Zhang, Liangren;
Cheung Lee, Hon;
Zhang, Lihe

Publication type:

Article

Anticancer effects of combinational treatment with BRAF<sup>V600E</sup> siRNA and PI3K pathway inhibitors in melanoma cell lines harboring BRAF<sup>V600E</sup>.

Published in:

Oncology Letters, 2018, v. 16, n. 1, p. 632, doi. 10.3892/ol.2018.8614

By:

He, Hongyan;
Nan, Xiyan;
Liu, Shuang;
Zhang, Liangren;
Yang, Zhenjun;
Wu, Yun;
Zhang, Lihe

Publication type:

Article

Evaluating reverse docking on general and selective inhibitors: a case study about glide.

Published in:

Journal of Chinese Pharmaceutical Sciences, 2020, v. 29, n. 10, p. 679, doi. 10.5246/jcps.2020.10.063

By:

Mingna Li;
Xing Wu;
Liangren Zhang;
Zhenming Liu

Publication type:

Article

Structure-based design and biological evaluation of novel mTOR inhibitors as potential anti-cervical agents.

Published in:

Journal of Chinese Pharmaceutical Sciences, 2020, v. 29, n. 9, p. 603, doi. 10.5246/jcps.2020.09.056

By:

Peili Jiao;
Yiyan Li;
Xing Wu;
Yuxi Wang;
Beibei Mao;
Hongwei Jin;
Lihe Zhang;
Liangren Zhang;
Zhenming Liu

Publication type:

Article

Designing natural product-like virtual libraries using deep molecule generative models.

Published in:

Journal of Chinese Pharmaceutical Sciences, 2018, v. 27, n. 7, p. 451, doi. 10.5246/jcps.2018.07.046

By:

Yibo Li;
Xin Zhou;
Zhenming Liu;
Liangren Zhang

Publication type:

Article

CMNPD: a comprehensive marine natural products database towards facilitating drug discovery from the ocean.

Published in:

Nucleic Acids Research, 2021, v. 49, n. D1, p. D509, doi. 10.1093/nar/gkaa763

By:

Lyu, Chuanyu;
Chen, Tong;
Qiang, Bo;
Liu, Ningfeng;
Wang, Heyu;
Zhang, Liangren;
Liu, Zhenming

Publication type:

Article

Soviet inspiration in Chinese archaeology.

Published in:

Antiquity, 2011, v. 85, n. 329, p. 1049, doi. 10.1017/S0003598X00068484

By:

Zhang Liangren

Publication type:

Article

The Discovery of Novel Vascular Endothelial Growth Factor Receptor Tyrosine Kinases Inhibitors: Pharmacophore Modeling, Virtual Screening and Docking Studies.

Published in:

Chemical Biology & Drug Design, 2007, v. 69, n. 3, p. 204, doi. 10.1111/j.1747-0285.2007.00488.x

By:

Hui Yu;
Wang, Zhanli;
Zhang, Liangren;
Zhang, Jufeng;
Huang, Qian

Publication type:

Article

CHINESE LACQUERWARES FROM BEGRAM: DATE AND PROVENANCE.

Published in:

International Journal of Asian Studies, 2011, v. 8, n. 1, p. 1, doi. 10.1017/S1479591410000239

By:

Zhang, Liangren

Publication type:

Article

Multiple Oxidative Dehydrogenative Functionalization of Arylacetaldehydes Using Molecular Oxygen as Oxidant Leading to 2-Oxo-acetamidines.

Published in:

Advanced Synthesis & Catalysis, 2012, v. 354, n. 7, p. 1293, doi. 10.1002/adsc.201100892

By:

Zhang, Chun;
Zhang, Liangren;
Jiao, Ning

Publication type:

Article

Design, Synthesis and SAR Studies of NAD Analogues as Potent Inhibitors towards CD38 NADase.

Published in:

Molecules, 2014, v. 19, n. 10, p. 15754, doi. 10.3390/molecules191015754

By:

Shengjun Wang;
Wenjie Zhu;
Xuan Wang;
Jianguo Li;
Kehui Zhang;
Liangren Zhang;
Yong-Juan Zhao;
Hon Cheung Lee;
Lihe Zhang

Publication type:

Article

Synthesis and Calcium Mobilization Activity of cADPR Analogues Which Integrate Nucleobase, Northern and Southern Ribose Modifications.

Published in:

Molecules, 2012, v. 17, n. 4, p. 4343, doi. 10.3390/molecules17044343

By:

Yue Zhou;
Peilin Yu;
Hongwei Jin;
Zhenjun Yang;
Jianbo Yue;
Liangren Zhang;
Lihe Zhang

Publication type:

Article

Synthesis and SAR Study of Novel Peptide Aldehydes as Inhibitors of 20S Proteasome.

Published in:

Molecules, 2011, v. 16, n. 9, p. 7551, doi. 10.3390/molecules16097551

By:

Yuheng Ma;
Bo Xu;
Yuan Fang;
Zhenjun Yang;
Jingrong Cui;
Liangren Zhang;
Lihe Zhang

Publication type:

Article

Concise Syntheses of Trifluoromethylated Cyclic and Acyclic Analogues of cADPR.

Published in:

Molecules, 2010, v. 15, n. 12, p. 8689, doi. 10.3390/molecules15128689

By:

Xiangchen Huang;
Min Dong;
Jian Liu;
Kehui Zhang;
Zhenjun Yang;
Liangren Zhang;
Lihe Zhang

Publication type:

Article

Toll-Like Receptor 7 Agonists: Chemical Feature Based Pharmacophore Identification and Molecular Docking Studies.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0056514

By:

Yu, Hui;
Jin, Hongwei;
Sun, Lidan;
Zhang, Liangren;
Sun, Gang;
Wang, Zhanli;
Yu, Yongchun

Publication type:

Article

A Cell Permeable NPE Caged ADP-Ribose for Studying TRPM2.

Published in:

PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0051028

By:

Peilin Yu;
Qian Wang;
Li-He Zhang;
Hon-Cheung Lee;
Liangren Zhang;
Jianbo Yue

Publication type:

Article

Design, synthesis and biological evaluation of indolizine derivatives as HIV-1 VIF-ElonginC interaction inhibitors.

Published in:

Molecular Diversity, 2013, v. 17, n. 2, p. 221, doi. 10.1007/s11030-013-9424-3

By:

Huang, Wenlin;
Zuo, Tao;
Jin, Hongwei;
Liu, Zhenming;
Yang, Zhenjun;
Yu, Xianghui;
Zhang, Liangren;
Zhang, Lihe

Publication type:

Article

Design, Synthesis and Preliminary Biological Evaluation of Purine-2,6-diamine Derivatives as Cyclin-dependent Kinase (CDK) Inhibitors.

Published in:

Chinese Journal of Chemistry, 2013, v. 31, n. 9, p. 1181, doi. 10.1002/cjoc.201300420

By:

Wang, Junhua;
Wang, Quande;
Zhang, Liangren;
Fang, Hao

Publication type:

Article

Novel Dithiocarbamic Acid Esters Derived from 6-Aminomethyl-4-anilinoquinazolines and 6-Aminomethyl-4-anilino-3-cyanoquinolines as Potent EGFR Inhibitors.

Published in:

Archiv der Pharmazie, 2013, v. 346, n. 1, p. 44, doi. 10.1002/ardp.201200267

By:

Zhang, Xin;
Li, Ridong;
Qiao, Kang;
Ge, Zemei;
Zhang, Liangren;
Cheng, Tieming;
Li, Runtao

Publication type:

Article

Solid-Phase Synthesis of Dipeptide-Conjugated Nucleosides and Their Interaction with RNA.

Published in:

Helvetica Chimica Acta, 2003, v. 86, n. 10, p. 3516

By:

Guimin Dong;
Liangren Zhang;
Lihe Zhang

Publication type:

Article

Identification and Structure-Activity Studies of 1,3-Dibenzyl-2-aryl imidazolidines as Novel Hsp90 Inhibitors.

Published in:

Molecules, 2019, v. 24, n. 11, p. 2105, doi. 10.3390/molecules24112105

By:

Liu, Yajun;
Liu, Xiaoxia;
Li, Lihong;
Dai, Rui;
Shi, Meiyun;
Xue, Hongyu;
Liu, Yong;
Wang, Hecheng;
Zhang, Liangren

Publication type:

Article

Molecular Mechanism of Action of RORγt Agonists and Inverse Agonists: Insights from Molecular Dynamics Simulation.

Published in:

Molecules, 2018, v. 23, n. 12, p. 3181, doi. 10.3390/molecules23123181

By:

Sun, Nannan;
Yuan, Congmin;
Ma, Xiaojun;
Wang, Yonghui;
Gu, Xianfeng;
Fu, Wei;
Zhang, Liangren;
McPhee, Derek J.

Publication type:

Article

Scale-Up Synthesis and Identification of GLYX-13, a NMDAR Glycine-Site Partial Agonist for the Treatment of Major Depressive Disorder.

Published in:

Molecules, 2018, v. 23, n. 5, p. 996, doi. 10.3390/molecules23050996

By:

Li, Wenchao;
Liu, Jingjian;
Fan, Minghua;
Li, Zhongtang;
Chen, Yin;
Zhang, Guisen;
Huang, Zhuo;
Zhang, Liangren

Publication type:

Article