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Development of human lactate dehydrogenase a inhibitors: high-throughput screening, molecular dynamics simulation and enzyme activity assay.
- Published in:
- Journal of Computer-Aided Molecular Design, 2024, v. 38, n. 1, p. 1, doi. 10.1007/s10822-024-00568-y
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- Article
Discovery of the Inhibitor Targeting the SLC7A11/xCT Axis through In Silico and In Vitro Experiments.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 15, p. 8284, doi. 10.3390/ijms25158284
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- Article
ToxMPNN: A deep learning model for small molecule toxicity prediction.
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- Journal of Applied Toxicology, 2024, v. 44, n. 7, p. 953, doi. 10.1002/jat.4591
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- Article
Small Open Reading Frame-Encoded Micro-Peptides: An Emerging Protein World.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 13, p. 10562, doi. 10.3390/ijms241310562
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- Article
Dual-sensitive antibacterial peptide nanoparticles prevent dental caries.
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- Theranostics, 2022, v. 12, n. 10, p. 4818, doi. 10.7150/thno.73181
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- Article
A Novel Spider Toxin Inhibits Fast Inactivation of the Na<sub>v</sub>1.9 Channel by Binding to Domain III and Domain IV Voltage Sensors.
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- Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.778534
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- Article
Variation of Two S3b Residues in K<sub>V</sub>4.1–4.3 Channels Underlies Their Different Modulations by Spider Toxin κ-LhTx-1.
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- Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.692076
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- Article
Molecular diversification of antimicrobial peptides from the wolf spider Lycosa sinensis venom based on peptidomic, transcriptomic, and bioinformatic analyses.
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- Acta Biochimica et Biophysica Sinica, 2020, v. 52, n. 11, p. 1274, doi. 10.1093/abbs/gmaa107
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- Article
Scorpion toxin inhibits the voltage-gated proton channel using a Zn<sup>2+</sup> -like long-range conformational coupling mechanism.
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- 2020
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- Publication type:
- journal article
Spider venom-derived peptide induces hyperalgesia in Nav1.7 knockout mice by activating Nav1.9 channels.
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- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16210-y
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- Publication type:
- Article
Purification and Characterization of JZTx-14, a Potent Antagonist of Mammalian and Prokaryotic Voltage-Gated Sodium Channels.
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- Toxins, 2018, v. 10, n. 10, p. 408, doi. 10.3390/toxins10100408
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- Publication type:
- Article
Engineering Gain-of-Function Analogues of the Spider Venom Peptide HNTX-I, A Potent Blocker of the hNaV1.7 Sodium Channel.
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- Toxins, 2018, v. 10, n. 9, p. 358, doi. 10.3390/toxins10090358
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- Publication type:
- Article
Purification and Characterization of a Novel Insecticidal Toxin, μ-sparatoxin-Hv2, from the Venom of the Spider Heteropoda venatoria.
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- Toxins, 2018, v. 10, n. 6, p. 233, doi. 10.3390/toxins10060233
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- Article
A Chimeric NaV1.8 Channel Expression System Based on HEK293T Cell Line.
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- Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00337
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- Publication type:
- Article
Electrophysiological and Pharmacological Analyses of Nav1.9 Voltage-Gated Sodium Channel by Establishing a Heterologous Expression System.
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- Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00852
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- Publication type:
- Article
A novel tarantula toxin stabilizes the deactivated voltage sensor of bacterial sodium channel.
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- FASEB Journal, 2017, v. 31, n. 7, p. 3167, doi. 10.1096/fj.201600882R
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- Article
Molecular Basis of the Receptor Interactions of Polysialic Acid (polySia), polySia Mimetics, and Sulfated Polysaccharides.
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- ChemMedChem, 2016, v. 11, n. 9, p. 990, doi. 10.1002/cmdc.201500609
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- Publication type:
- Article
A Comparative Analysis of the Venom Gland Transcriptomes of the Fishing Spiders Dolomedes mizhoanus and Dolomedes sulfurous.
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- PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0139908
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- Publication type:
- Article
Synergetic Action of Domain II and IV Underlies Persistent Current Generation in Na<sub>v</sub>1.3 as revealed by a tarantula toxin.
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- Scientific Reports, 2015, p. 9241, doi. 10.1038/srep09241
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- Publication type:
- Article
Rat liver sinusoidal surface N-linked glycoproteomic analysis by affinity enrichment and mass spectrometric identification.
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- Biochemistry (00062979), 2015, v. 80, n. 3, p. 260, doi. 10.1134/S0006297915030025
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- Publication type:
- Article
The Activation Effect of Hainantoxin-I, a Peptide Toxin from the Chinese Spider, Ornithoctonus hainana, on Intermediate-Conductance Ca<sup>2+</sup>-Activated K<sup>+</sup> Channels.
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- Toxins, 2014, v. 6, n. 8, p. 2568, doi. 10.3390/toxins6082568
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- Publication type:
- Article
Molecular Surface of JZTX-V (β-Theraphotoxin-Cj2a) Interacting with Voltage-Gated Sodium Channel Subtype Na<sub>V</sub>1.4.
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- Toxins, 2014, v. 6, n. 7, p. 2177, doi. 10.3390/toxins6072177
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- Publication type:
- Article
Toxin Diversity Revealed by a Transcriptomic Study of <i>Ornithoctonus huwena</i>.
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- PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0100682
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- Publication type:
- Article
Physiological and Biochemical Analysis to Reveal the Molecular Basis for Black Widow Spiderling Toxicity.
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- Journal of Biochemical & Molecular Toxicology, 2014, v. 28, n. 5, p. 198, doi. 10.1002/jbt.21553
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- Publication type:
- Article
A method combining SPITC and <sup>18</sup>O labeling for simultaneous protein identification and relative quantification.
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- Journal of Mass Spectrometry, 2014, v. 49, n. 5, p. 400, doi. 10.1002/jms.3357
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- Publication type:
- Article
Characterization of a Novel BmαTX47 Toxin Modulating Sodium Channels: The Crucial Role of Expression Vectors in Toxin Pharmacological Activity.
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- Toxins, 2014, v. 6, n. 3, p. 816, doi. 10.3390/toxins6030816
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- Publication type:
- Article
The Venom of the Spider Selenocosmia Jiafu Contains Various Neurotoxins Acting on Voltage-Gated Ion Channels in Rat Dorsal Root Ganglion Neurons.
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- Toxins, 2014, v. 6, n. 3, p. 988, doi. 10.3390/toxins6030988
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- Publication type:
- Article
Synaptotagmin I delays the fast inactivation of Kv1.4 channel through interaction with its N-terminus.
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- Molecular Brain, 2014, v. 7, n. 1, p. 1, doi. 10.1186/1756-6606-7-4
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- Publication type:
- Article
The Venom Gland Transcriptome of <i>Latrodectus tredecimguttatus</i> Revealed by Deep Sequencing and cDNA Library Analysis.
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- PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0081357
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- Publication type:
- Article
Purification and Partial Characterization of a Novel Neurotoxic Protein from Eggs of Black Widow Spiders ( Latrodectus tredecimguttatus).
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- Journal of Biochemical & Molecular Toxicology, 2013, v. 27, n. 7, p. 337, doi. 10.1002/jbt.21493
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- Publication type:
- Article
Native Pyroglutamation of Huwentoxin-IV: A Post-Translational Modification that Increases the Trapping Ability to the Sodium Channel.
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- PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0065984
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- Article
Beneficial Effects of Trypsin Inhibitors Derived from a Spider Venom Peptide in L-Arginine-Induced Severe Acute Pancreatitis in Mice.
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- PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0061049
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- Publication type:
- Article
Sodium Laurate, a Novel Protease- and Mass Spectrometry-Compatible Detergent for Mass Spectrometry-Based Membrane Proteomics.
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- PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0059779
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- Publication type:
- Article
Isolation technique and proteomic analysis of the erythrocyte ghosts of red-eared turtle ( Trachemys scripta).
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- Electrophoresis, 2013, v. 34, n. 2, p. 215, doi. 10.1002/elps.201200243
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- Article
Protein Compositional Analysis of the Eggs of Black Widow Spider ( Latrodectus tredecimguttatus): Implications for the Understanding of Egg Toxicity.
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- Journal of Biochemical & Molecular Toxicology, 2012, v. 26, n. 12, p. 510, doi. 10.1002/jbt.21460
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- Article
Sample preparation for the analysis of membrane proteomes by mass spectrometry.
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- Protein & Cell, 2012, v. 3, n. 9, p. 661, doi. 10.1007/s13238-012-2062-1
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- Article
Electrophoretically driven SDS removal and protein fractionation in the shotgun analysis of membrane proteomes.
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- Electrophoresis, 2012, v. 33, n. 2, p. 316, doi. 10.1002/elps.201100364
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- Publication type:
- Article
Shotgun proteomics and network analysis of ubiquitin-related proteins from human breast carcinoma epithelial cells.
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- Molecular & Cellular Biochemistry, 2012, v. 359, n. 1/2, p. 375, doi. 10.1007/s11010-011-1031-y
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- Publication type:
- Article
Electrophysiological characterization of NSCs after differentiation induced by OEC conditioned medium.
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- Acta Neurochirurgica, 2011, v. 153, n. 10, p. 2085, doi. 10.1007/s00701-011-0955-z
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- Publication type:
- Article
Molecular basis of the tarantula toxin jingzhaotoxin-III (β-TRTX-Cj1α) interacting with voltage sensors in sodium channel subtype Nav1.5.
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- FASEB Journal, 2011, v. 25, n. 9, p. 3177, doi. 10.1096/fj.10-178848
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- Publication type:
- Article
Functional Expression of Spider Neurotoxic Peptide Huwentoxin-I in E. coli.
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- PLoS ONE, 2011, v. 6, n. 6, p. 1, doi. 10.1371/journal.pone.0021608
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- Publication type:
- Article
Dried polyacrylamide gel absorption: A method for efficient elimination of the interferences from SDS-solubilized protein samples in mass spectrometry-based proteome analysis.
- Published in:
- Electrophoresis, 2010, v. 31, n. 23/24, p. 3816, doi. 10.1002/elps.201000255
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- Publication type:
- Article
Proteomics analysis of plasma membrane from liver sinusoidal endothelial cells after partial hepatectomy by an improved two-dimensional electrophoresis.
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- Molecular & Cellular Biochemistry, 2010, v. 344, n. 1/2, p. 137, doi. 10.1007/s11010-010-0537-z
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- Publication type:
- Article
Evaluation and optimization of removal of an acid-insoluble surfactant for shotgun analysis of membrane proteome.
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- Electrophoresis, 2010, v. 31, n. 16, p. 2705, doi. 10.1002/elps.201000161
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- Publication type:
- Article
Development of cationic colloidal silica-coated magnetic nanospheres for highly selective and rapid enrichment of plasma membrane fractions for proteomics analysis.
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- Biotechnology & Applied Biochemistry, 2009, v. 54, n. 4, p. 213, doi. 10.1042/BA20090187
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- Publication type:
- Article
Analysis of integral membrane proteins by heat gel-embedment combined with improved in-gel digestions.
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- Electrophoresis, 2009, v. 30, n. 23, p. 4109, doi. 10.1002/elps.200900391
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- Publication type:
- Article
Improvement of gel-separated protein identification by DMF-assisted digestion and peptide recovery after electroblotting.
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- Electrophoresis, 2009, v. 30, n. 20, p. 3626, doi. 10.1002/elps.200900070
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- Publication type:
- Article
Transcriptional Regulation of PP2A-Aα Is Mediated by Multiple Factors Including AP-2α, CREB, ETS-1, and SP-1.
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- PLoS ONE, 2009, v. 4, n. 9, p. 1, doi. 10.1371/journal.pone.0007019
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- Publication type:
- Article
Proteomic analysis of Latrodectus tredecimguttatus venom for uncovering potential latrodectism-related proteins.
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- Journal of Biochemical & Molecular Toxicology, 2008, v. 22, n. 5, p. 328, doi. 10.1002/jbt.20244
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- Publication type:
- Article
A proteomic study reveals the diversified distribution of plasma membrane-associated proteins in rat hepatocytes.
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- Journal of Cellular Biochemistry, 2008, v. 104, n. 3, p. 965, doi. 10.1002/jcb.21680
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- Publication type:
- Article