Works matching AU Li, Zheng Jian

Results: 91

Intermolecular Dearomative 1,2‐Amination/Carbonylation via Nucleophilic Addition of Simple Amines to Arene π‐Bonds.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 36, p. 1, doi. 10.1002/chem.202300776

By:

Li, Zheng‐Jian;
Wang, Ming‐Yang;
Li, Chu‐Qiao;
Zeng, Wei‐Long;
Li, Wei

Publication type:

Article

Improved Titer in Late-Stage Mammalian Cell Culture Manufacturing by Re-Cloning.

Published in:

Bioengineering (Basel), 2022, v. 9, n. 4, p. 173, doi. 10.3390/bioengineering9040173

By:

He, Qin;
Rehmann, Matthew S.;
Tian, Jun;
Xu, Jianlin;
Sabino, Luzmary;
Vandermark, Erik;
Basson, Ziev;
Po, Iris;
Bierilo, Kathleen;
Tremml, Gabi;
Rizzi, Giovanni;
Langsdorf, Erik F.;
Qian, Nan-Xin;
Borys, Michael C.;
Khetan, Anurag;
Li, Zheng-Jian

Publication type:

Article

N-1 Perfusion Platform Development Using a Capacitance Probe for Biomanufacturing.

Published in:

Bioengineering (Basel), 2022, v. 9, n. 4, p. 128, doi. 10.3390/bioengineering9040128

By:

Rittershaus, Emily S. C.;
Rehmann, Matthew S.;
Xu, Jianlin;
He, Qin;
Hill, Charles;
Swanberg, Jeffrey;
Borys, Michael C.;
Li, Zheng-Jian;
Khetan, Anurag

Publication type:

Article

Evaluation indices of greenhouse gas mitigation technologies in cropland ecosystem.

Published in:

Chinese Journal of Applied Ecology / Yingyong Shengtai Xuebao, 2015, v. 26, n. 1, p. 297

By:

LI Jian-zheng;
WANG Ying-chun;
WANG Li-gang;
LI Hu;
QIU Jian-jun;
WANG Dao-long

Publication type:

Article

Modeling scalability of impurity precipitation in downstream biomanufacturing.

Published in:

Biotechnology Progress, 2024, v. 40, n. 4, p. 1, doi. 10.1002/btpr.3454

By:

Guo, Jing;
Traylor, Steven J.;
Agoub, Mohamed;
Jin, Weixin;
Hua, Helen;
Diemer, R. Bertrum;
Xu, Xuankuo;
Ghose, Sanchayita;
Li, Zheng Jian;
Lenhoff, Abraham M.

Publication type:

Article

Antibody charge variant modulation by in vitro enzymatic treatment in different Chinese hamster ovary cell cultures.

Published in:

Biotechnology Progress, 2022, v. 38, n. 5, p. 1, doi. 10.1002/btpr.3268

By:

Xu, Jianlin;
Santos, Johanna;
Anderson, Nadine S.;
Borys, Michael C.;
Pendse, Girish;
Li, Zheng Jian

Publication type:

Article

Role of membrane structure on the filtrate flux during monoclonal antibody filtration through virus retentive membranes.

Published in:

Biotechnology Progress, 2022, v. 38, n. 2, p. 1, doi. 10.1002/btpr.3231

By:

Billups, Matthew;
Minervini, Mirko;
Holstein, Melissa;
Feroz, Hasin;
Ranjan, Swarnim;
Hung, Jessica;
Bao, Haiying;
Li, Zheng Jian;
Ghose, Sanchayita;
Zydney, Andrew L.

Publication type:

Article

Process analytics 4.0: A paradigm shift in rapid analytics for biologics development.

Published in:

Biotechnology Progress, 2021, v. 37, n. 4, p. 1, doi. 10.1002/btpr.3177

By:

Wasalathanthri, Dhanuka P.;
Shah, Ruchir;
Ding, Julia;
Leone, Anthony;
Li, Zheng Jian

Publication type:

Article

Control of leached beta‐glucan levels from depth filters by an improved depth filtration flush strategy.

Published in:

Biotechnology Progress, 2021, v. 37, n. 1, p. 1, doi. 10.1002/btpr.3086

By:

Holstein, Melissa;
Jang, Dongyoun;
Urrea, Christine;
Botta, Lakshmi Sirisha;
Grimm, William;
Ghose, Sanchayita;
Li, Zheng Jian

Publication type:

Article

Mechanistic insights into viral clearance during the chromatography steps in antibody processes by using virus surrogates.

Published in:

Biotechnology Progress, 2020, v. 36, n. 6, p. 1, doi. 10.1002/btpr.3057

By:

Dyer, Rachel;
Song, Yuanli;
Chen, Jie;
Bigelow, Elizabeth;
McGinnis, Jennifer;
Jenkins, Lauren;
Ghose, Sanchayita;
Li, Zheng Jian

Publication type:

Article

Effective temperature shift strategy development and scale confirmation for simultaneous optimization of protein productivity and quality in Chinese hamster ovary cells.

Published in:

Biotechnology Progress, 2020, v. 36, n. 3, p. 1, doi. 10.1002/btpr.2959

By:

McHugh, Kyle P.;
Xu, Jianlin;
Aron, Kathryn L.;
Borys, Michael C.;
Li, Zheng Jian

Publication type:

Article

Kinetic modeling of Chinese hamster ovary cell culture: factors and principles.

Published in:

Critical Reviews in Biotechnology, 2020, v. 40, n. 2, p. 265, doi. 10.1080/07388551.2019.1711015

By:

Tang, Peifeng;
Xu, Jianlin;
Louey, Alastair;
Tan, Zhijun;
Yongky, Andrew;
Liang, Shaoyan;
Li, Zheng Jian;
Weng, Yongyan;
Liu, Shijie

Publication type:

Article

Estimation of hyphal tensile strength in production-scale Aspergillus oryzae fungal fermentations.

Published in:

Biotechnology & Bioengineering, 2002, v. 77, n. 6, p. 601, doi. 10.1002/bit.10209

By:

Li, Zheng Jian;
Shukla, Vivek;
Wenger, Kevin;
Fordyce, Andrew;
Pedersen, Annemarie Gade;
Marten, Mark

Publication type:

Article

Fungal morphology and fragmentation behavior in a fed-batch Aspergillus oryzae fermentation at the production scale.

Published in:

Biotechnology & Bioengineering, 2000, v. 70, n. 3, p. 300, doi. 10.1002/1097-0290(20001105)70:3<300::AID-BIT7>3.0.CO;2-3

By:

Li, Zheng Jian;
Shukla, Vivek;
Fordyce, Andrew P.;
Pedersen, Annemarie Gade;
Wenger, Kevin S.;
Marten, Mark R.

Publication type:

Article

On-column disulfide bond formation of monoclonal antibodies during Protein A chromatography eliminates low molecular weight species and rescues reduced antibodies.

Published in:

2020

By:

Tan, Zhijun;
Ehamparanathan, Vivekh;
Ren, Tingwei;
Tang, Peifeng;
Hoffman, Laurel;
Kuang, June;
Liu, Peiran;
Huang, Chao;
Du, Cheng;
Tao, Li;
Chemmalil, Letha;
Lewandowski, Angela;
Ghose, Sanchayita;
Li, Zheng Jian;
Liu, Shijie

Publication type:

Report

Design of next-generation therapeutic IgG4 with improved manufacturability and bioanalytical characteristics.

Published in:

mAbs (1942-0862), 2020, v. 12, n. 1, p. 1, doi. 10.1080/19420862.2020.1829338

By:

Chen, Zhiqiang;
Qian, Yueming;
Song, Yuanli;
Xu, Xuankuo;
Tao, Li;
Mussa, Nesredin;
Ghose, Sanchayita;
Li, Zheng Jian

Publication type:

Article

Optimization and kinetic modeling of interchain disulfide bond reoxidation of monoclonal antibodies in bioprocesses.

Published in:

2020

By:

Tang, Peifeng;
Tan, Zhijun;
Ehamparanathan, Vivekh;
Ren, Tingwei;
Hoffman, Laurel;
Du, Cheng;
Song, Yuanli;
Tao, Li;
Lewandowski, Angela;
Ghose, Sanchayita;
Li, Zheng Jian;
Liu, Shijie

Publication type:

Report

Biomanufacturing evolution from conventional to intensified processes for productivity improvement: a case study.

Published in:

2020

By:

Xu, Jianlin;
Xu, Xuankuo;
Huang, Chao;
Angelo, James;
Oliveira, Christopher L.;
Xu, Mengmeng;
Xu, Xia;
Temel, Deniz;
Ding, Julia;
Ghose, Sanchayita;
Borys, Michael C.;
Li, Zheng Jian

Publication type:

Report

Protein aggregation and mitigation strategy in low pH viral inactivation for monoclonal antibody purification.

Published in:

2019

By:

Jin, Weixin;
Xing, Zizhuo;
Song, Yuanli;
Huang, Chao;
Xu, Xuankuo;
Ghose, Sanchayita;
Li, Zheng Jian

Publication type:

Report

Process intensification in fed-batch production bioreactors using non-perfusion seed cultures.

Published in:

2019

By:

Yongky, Andrew;
Xu, Jianlin;
Tian, Jun;
Oliveira, Christopher;
Zhao, Jia;
McFarland, Kevin;
Borys, Michael C.;
Li, Zheng Jian

Publication type:

Report

Modulating cell culture oxidative stress reduces protein glycation and acidic charge variant formation.

Published in:

mAbs (1942-0862), 2019, v. 11, n. 1, p. 205, doi. 10.1080/19420862.2018.1537533

By:

Chung, Stanley;
Tian, Jun;
Tan, Zhijun;
Chen, Jie;
Zhang, Na;
Huang, Yunping;
Vandermark, Erik;
Lee, Jongchan;
Borys, Michael;
Li, Zheng Jian

Publication type:

Article

Systematic development of temperature shift strategies for Chinese hamster ovary cells based on short duration cultures and kinetic modeling.

Published in:

mAbs (1942-0862), 2019, v. 11, n. 1, p. 191, doi. 10.1080/19420862.2018.1525262

By:

Xu, Jianlin;
Tang, Peifeng;
Yongky, Andrew;
Drew, Barry;
Borys, Michael C.;
Liu, Shijie;
Li, Zheng Jian

Publication type:

Article

Improving titer while maintaining quality of final formulated drug substance via optimization of CHO cell culture conditions in low-iron chemically defined media.

Published in:

mAbs (1942-0862), 2018, v. 10, n. 3, p. 488, doi. 10.1080/19420862.2018.1433978

By:

Xu, Jianlin;
Rehmann, Matthew S.;
Xu, Xuankuo;
Huang, Chao;
Tian, Jun;
Qian, Nan-Xin;
Li, Zheng Jian

Publication type:

Article

Using hydrogen peroxide to prevent antibody disulfide bond reduction during manufacturing process.

Published in:

mAbs (1942-0862), 2018, v. 10, n. 3, p. 500, doi. 10.1080/19420862.2018.1424609

By:

Du, Cheng;
Huang, Yunping;
Borwankar, Ameya;
Tan, Zhijun;
Cura, Anthony;
Yee, Joon Chong;
Singh, Nripen;
Ludwig, Richard;
Borys, Michael;
Ghose, Sanchayita;
Mussa, Nesredin;
Li, Zheng Jian

Publication type:

Article

Monoclonal antibody higher order structure analysis by high throughput protein conformational array.

Published in:

mAbs (1942-0862), 2018, v. 10, n. 3, p. 397, doi. 10.1080/19420862.2017.1421880

By:

Song, Yuanli;
Yu, Deqiang;
Mayani, Mukesh;
Mussa, Nesredin;
Li, Zheng Jian

Publication type:

Article

Development of adsorptive hybrid filters to enable two-step purification of biologics.

Published in:

mAbs (1942-0862), 2017, v. 9, n. 2, p. 350, doi. 10.1080/19420862.2016.1267091

By:

Singh, Nripen;
Arunkumar, Abhiram;
Peck, Michael;
Voloshin, Alexei M.;
Moreno, Angela M.;
Tan, Zhijun;
Hester, Jonathan;
Borys, Michael C.;
Li, Zheng Jian

Publication type:

Article

Fermentative Hydrogen Production from Soybean Protein Processing Wastewater in an Anaerobic Baffled Reactor (ABR) Using Anaerobic Mixed Consortia.

Published in:

Applied Biochemistry & Biotechnology, 2012, v. 168, n. 1, p. 91, doi. 10.1007/s12010-011-9357-1

By:

Zhu, Ge-fu;
Li, Jian-zheng;
Liu, Chao-xiang

Publication type:

Article

The myb transcription factor MdMYB6 suppresses anthocyanin biosynthesis in transgenic Arabidopsis.

Published in:

Plant Cell, Tissue & Organ Culture, 2011, v. 106, n. 2, p. 235, doi. 10.1007/s11240-010-9912-4

By:

Jian-Jie Gao;
Xue-Fang Shen;
Zhen Zhang;
Ri-He Peng;
Ai-Sheng Xiong;
Jing Xu;
Bo Zhu;
Jian-Li Zheng;
Quan-Hong Yao

Publication type:

Article

Control of recombinant human endostatin production in fed-batch cultures of Pichia pastoris using the methanol feeding rate.

Published in:

Biotechnology Letters, 2002, v. 24, n. 19, p. 1631, doi. 10.1023/A:1020357732474

By:

Jian Li, Zheng;
Zhao, Qinghua;
Liang, Hong;
Jiang, Shunlin;
Chen, Tom;
Grella, Davida;
Shearon, Colleen;
Bottaro, Donald P.;
Sim, B. Kim Lee

Publication type:

Article

Measurements of the fragmentation rate constant imply that the tensile strength of fungal hyphae can change significantly during growth.

Published in:

Biotechnology Letters, 2002, v. 24, n. 1, p. 1, doi. 10.1023/A:1013848325193

By:

Li, Zheng Jian;
Bhargava, Swapnil;
Marten, Mark R.

Publication type:

Article

A mechanistic kinetic description of lactate dehydrogenase elucidating cancer diagnosis and inhibitor evaluation.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2017, v. 32, n. 1, p. 564, doi. 10.1080/14756366.2016.1275606

By:

Tang, Peifeng;
Xu, Jianlin;
Oliveira, Christopher L.;
Li, Zheng Jian;
Liu, Shijie

Publication type:

Article

Minimization of artifact protein aggregation using tetradecyl sulfate and hexadecyl sulfate in capillary gel electrophoresis under reducing conditions.

Published in:

Electrophoresis, 2020, v. 41, n. 13/14, p. 1245, doi. 10.1002/elps.201900435

By:

Guan, Qian;
Atsma, Jennifer;
Tulsan, Rekha;
Voronov, Sergey;
Ding, Julia;
Beckman, Jeff;
Li, Zheng Jian

Publication type:

Article

Inside Front cover: Minimization of artifact protein aggregation using tetradecyl sulfate and hexadecyl sulfate in capillary gel electrophoresis under reducing conditions.

Published in:

Electrophoresis, 2020, v. 41, n. 13/14, p. NA, doi. 10.1002/elps.202070072

By:

Guan, Qian;
Atsma, Jennifer;
Tulsan, Rekha;
Voronov, Sergey;
Ding, Julia;
Beckman, Jeff;
Li, Zheng Jian

Publication type:

Article

Numerical investigation of the concentric annulus flow around a cylindrical body with contrasted effecting factors.

Published in:

Journal of Hydrodynamics, 2015, v. 27, n. 2, p. 273, doi. 10.1016/S1001-6058(15)60482-6

By:

ZHANG, Xue-lan;
SUN, Xi-huan;
LI, Yong-ye;
XI, Xia-nan;
GUO, Fei;
ZHENG, Li-jian

Publication type:

Article

Increased MSX level improves biological productivity and production stability in multiple recombinant GS CHO cell lines.

Published in:

Engineering in Life Sciences, 2020, v. 20, n. 3/4, p. 112, doi. 10.1002/elsc.201900124

By:

Tian, Jun;
He, Qin;
Oliveira, Christopher;
Qian, Yueming;
Egan, Susan;
Xu, Jianlin;
Qian, Nan‐Xin;
Langsdorf, Erik;
Warrack, Bethanne;
Aranibar, Nelly;
Reily, Michael;
Borys, Michael;
Li, Zheng Jian

Publication type:

Article

Understanding the pathway and kinetics of aspartic acid isomerization in peptide mapping methods for monoclonal antibodies.

Published in:

Analytical & Bioanalytical Chemistry, 2021, v. 413, n. 8, p. 2113, doi. 10.1007/s00216-021-03176-z

By:

Kuang, June;
Tao, Yuanqi;
Song, Yuanli;
Chemmalil, Letha;
Mussa, Nesredin;
Ding, Julia;
Li, Zheng Jian

Publication type:

Article

Therapeutic protein purity and fragmented species characterization by capillary electrophoresis sodium dodecyl sulfate using systematic hybrid cleavage and forced degradation.

Published in:

Analytical & Bioanalytical Chemistry, 2019, v. 411, n. 21, p. 5617, doi. 10.1007/s00216-019-01942-8

By:

Duhamel, Lauren;
Gu, Yan;
Barnett, Gregory;
Tao, Yuanqi;
Voronov, Sergey;
Ding, Julia;
Mussa, Nesredin;
Li, Zheng Jian

Publication type:

Article

Assessment of CE-based baseline disturbances using simulation and targeted experimental evaluation—impact on the purity determination of therapeutic proteins.

Published in:

Analytical & Bioanalytical Chemistry, 2019, v. 411, n. 11, p. 2425, doi. 10.1007/s00216-019-01704-6

By:

Gu, Yan;
Voronov, Sergey;
Ding, Julia;
Mussa, Nesredin;
Li, Zheng Jian

Publication type:

Article

Optimal and consistent protein glycosylation in mammalian cell culture.

Published in:

Glycobiology, 2009, v. 19, n. 9, p. 936, doi. 10.1093/glycob/cwp079

By:

Hossler, Patrick;
Khattak, Sarwat F.;
Zheng Jian Li

Publication type:

Article

Understanding and Controlling Sialylation in a CHO Fc-Fusion Process.

Published in:

PLoS ONE, 2016, v. 11, n. 6, p. 1, doi. 10.1371/journal.pone.0157111

By:

Lewis, Amanda M.;
Croughan, William D.;
Aranibar, Nelly;
Lee, Alison G.;
Warrack, Bethanne;
Abu-Absi, Nicholas R.;
Patel, Rutva;
Drew, Barry;
Borys, Michael C.;
Reily, Michael D.;
Li, Zheng Jian

Publication type:

Article

Virus inactivation at moderately low pH varies with virus and buffer properties.

Published in:

Biotechnology Journal, 2022, v. 17, n. 2, p. 1, doi. 10.1002/biot.202100320

By:

Joshi, Pratik U.;
Meingast, Christa L.;
Xu, Xuankuo;
Holstein, Melissa;
Feroz, Hasin;
Ranjan, Swarnim;
Ghose, Sanchayita;
Li, Zheng Jian;
Heldt, Caryn L.

Publication type:

Article

Surrogate model to screen for inactivation‐based clearance of enveloped viruses during biotherapeutics process development.

Published in:

Biotechnology Journal, 2021, v. 16, n. 12, p. 1, doi. 10.1002/biot.202100176

By:

Feroz, Hasin;
Cetnar, Daniel;
Hewlett, Robert;
Sharma, Satish;
Holstein, Melissa;
Ghose, Sanchayita;
Li, Zheng Jian

Publication type:

Article

Physiochemical properties of enveloped viruses and arginine dictate inactivation.

Published in:

Biotechnology Journal, 2021, v. 16, n. 7, p. 1, doi. 10.1002/biot.202000342

By:

Meingast, Christa L.;
Joshi, Pratik U.;
Turpeinen, Dylan G.;
Xu, Xuankuo;
Holstein, Melissa;
Feroz, Hasin;
Ranjan, Swarnim;
Ghose, Sanchayita;
Li, Zheng Jian;
Heldt, Caryn L.

Publication type:

Article

Combined metabolomics and proteomics reveals hypoxia as a cause of lower productivity on scale-up to a 5000-liter CHO bioprocess.

Published in:

Biotechnology Journal, 2016, v. 11, n. 9, p. 1190, doi. 10.1002/biot.201600030

By:

Gao, Yuanwei;
Ray, Somak;
Dai, Shujia;
Ivanov, Alexander R.;
Abu‐Absi, Nicholas R.;
Lewis, Amanda M.;
Huang, Zhuangrong;
Xing, Zizhuo;
Borys, Michael C.;
Li, Zheng Jian;
Karger, Barry L.

Publication type:

Article

Hypoxia influences protein transport and epigenetic repression of CHO cell cultures in shake flasks.

Published in:

Biotechnology Journal, 2014, v. 9, n. 11, p. 1413, doi. 10.1002/biot.201400315

By:

Qian, Yueming;
Xing, Zizhuo;
Lee, Sherry;
Mackin, Nancy A.;
He, Aiqing;
Kayne, Paul S.;
He, Qin;
Qian, Nan‐Xin;
Li, Zheng Jian

Publication type:

Article

Improving the growth of Rubrivivax gelatinosus cultivated in sewage environment.

Published in:

Bioprocess & Biosystems Engineering, 2015, v. 38, n. 1, p. 79, doi. 10.1007/s00449-014-1245-y

By:

Wu, Pan;
Li, Jian-zheng;
Wang, Yan-ling;
Tong, Qing-yue;
Liu, Xian-shu;
Du, Cong;
Li, Ning

Publication type:

Article

Mechanistic insights into inter-chain disulfide bond reduction of IgG1 and IgG4 antibodies.

Published in:

Applied Microbiology & Biotechnology, 2022, v. 106, n. 3, p. 1057, doi. 10.1007/s00253-022-11778-5

By:

Song, Yuanli;
Cai, Hui;
Tan, Zhijun;
Mussa, Nesredin;
Li, Zheng-Jian

Publication type:

Article

Metabolic understanding of disulfide reduction during monoclonal antibody production.

Published in:

Applied Microbiology & Biotechnology, 2020, v. 104, n. 22, p. 9655, doi. 10.1007/s00253-020-10916-1

By:

Cura, Anthony J.;
Xu, Xuankuo;
Egan, Susan;
Aron, Kathryn;
Jenkins, Lauren;
Hageman, Tyler;
Huang, Yunping;
Chollangi, Srinivas;
Borys, Michael;
Ghose, Sanchayita;
Li, Zheng Jian

Publication type:

Article

Research on the Evapotranspiration Characteristics of Winter Wheat Under Border Irrigation on the Loess Plateau Based on an Improved SW Model.

Published in:

Water Saving Irrigation, 2024, n. 10, p. 86, doi. 10.12396/jsgg.2024129

By:

WU Hong-xiang;
SUN Xi-huan;
ZHENG Li-jian;
MA Juan-juan;
WU Chao-bao

Publication type:

Article

Effects of Plastic Film Residues on Soil Moisture and Growth Characteristics of Protected Tomatoes.

Published in:

Water Saving Irrigation, 2022, n. 4, p. 65

By:

LI Zhuo-ran;
MA Juan-juan;
ZHENG Li-jian;
GUO Xiang-hong;
YANG Cai-xia;
CHEN Jin-ping

Publication type:

Article