Works by Li, Aitao

Results: 28

Solid‐Phase Gene Synthesis for Mutant Library Construction: The Future of Directed Evolution?

Published in:

ChemBioChem, 2018, v. 19, n. 19, p. 2023, doi. 10.1002/cbic.201800339

By:

Li, Aitao;
Sun, Zhoutong;
Reetz, Manfred T.

Publication type:

Article

Front Cover: Beating Bias in the Directed Evolution of Proteins: Combining High‐Fidelity on‐Chip Solid‐Phase Gene Synthesis with Efficient Gene Assembly for Combinatorial Library Construction (ChemBioChem 3/2018).

Published in:

ChemBioChem, 2018, v. 19, n. 3, p. 196, doi. 10.1002/cbic.201800010

By:

Li, Aitao;
Acevedo‐Rocha, Carlos G.;
Sun, Zhoutong;
Cox, Tony;
Xu, Jia Lucy;
Reetz, Manfred T.

Publication type:

Article

Beating Bias in the Directed Evolution of Proteins: Combining High‐Fidelity on‐Chip Solid‐Phase Gene Synthesis with Efficient Gene Assembly for Combinatorial Library Construction.

Published in:

ChemBioChem, 2018, v. 19, n. 3, p. 221, doi. 10.1002/cbic.201700540

By:

Li, Aitao;
Acevedo‐Rocha, Carlos G.;
Sun, Zhoutong;
Cox, Tony;
Xu, Jia Lucy;
Reetz, Manfred T.

Publication type:

Article

Available methods for assembling expression cassettes for synthetic biology.

Published in:

Applied Microbiology & Biotechnology, 2012, v. 93, n. 5, p. 1853, doi. 10.1007/s00253-012-3920-8

By:

Wang, Tianwen;
Ma, Xingyuan;
Zhu, Hu;
Li, Aitao;
Du, Guocheng;
Chen, Jian

Publication type:

Article

Transforming Inert Cycloalkanes into α,ω‐Diamines by Designed Enzymatic Cascade Catalysis.

Published in:

Angewandte Chemie, 2023, v. 135, n. 16, p. 1, doi. 10.1002/ange.202215935

By:

Zhang, Zhongwei;
Fang, Lin;
Wang, Fei;
Deng, Yu;
Jiang, Zhengbin;
Li, Aitao

Publication type:

Article

Die zentrale Rolle der Methodenentwicklung in der gerichteten Evolution selektiver Enzyme.

Published in:

Angewandte Chemie, 2020, v. 132, n. 32, p. 13304, doi. 10.1002/ange.201901491

By:

Qu, Ge;
Li, Aitao;
Acevedo‐Rocha, Carlos G.;
Sun, Zhoutong;
Reetz, Manfred T.

Publication type:

Article

Regio‐ and Stereoselective Steroid Hydroxylation at C7 by Cytochrome P450 Monooxygenase Mutants.

Published in:

Angewandte Chemie, 2020, v. 132, n. 30, p. 12599, doi. 10.1002/ange.202003139

By:

Li, Aitao;
Acevedo‐Rocha, Carlos G.;
D'Amore, Lorenzo;
Chen, Jinfeng;
Peng, Yaqin;
Garcia‐Borràs, Marc;
Gao, Chenghua;
Zhu, Jinmei;
Rickerby, Harry;
Osuna, Sílvia;
Zhou, Jiahai;
Reetz, Manfred T.

Publication type:

Article

Rücktitelbild: Chemo‐ and Regioselective Dihydroxylation of Benzene to Hydroquinone Enabled by Engineered Cytochrome P450 Monooxygenase (Angew. Chem. 3/2019).

Published in:

Angewandte Chemie, 2019, v. 131, n. 3, p. 930, doi. 10.1002/ange.201812093

By:

Zhou, Hangyu;
Wang, Binju;
Wang, Fei;
Yu, Xiaojuan;
Ma, Lixin;
Li, Aitao;
Reetz, Manfred T.

Publication type:

Article

Chemo‐ and Regioselective Dihydroxylation of Benzene to Hydroquinone Enabled by Engineered Cytochrome P450 Monooxygenase.

Published in:

Angewandte Chemie, 2019, v. 131, n. 3, p. 774, doi. 10.1002/ange.201812093

By:

Zhou, Hangyu;
Wang, Binju;
Wang, Fei;
Yu, Xiaojuan;
Ma, Lixin;
Li, Aitao;
Reetz, Manfred T.

Publication type:

Article

Active-site engineering of ω-transaminase from Ochrobactrum anthropi for preparation of L-2-aminobutyric acid.

Published in:

BMC Biotechnology, 2021, v. 21, n. 1, p. 1, doi. 10.1186/s12896-021-00713-7

By:

Zhang, Zhiwei;
Liu, Yang;
Zhao, Jing;
Li, Wenqiang;
Hu, Ruiwen;
Li, Xia;
Li, Aitao;
Wang, Yaping;
Ma, Lixin

Publication type:

Article

Transforming Inert Cycloalkanes into α,ω‐Diamines by Designed Enzymatic Cascade Catalysis.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 16, p. 1, doi. 10.1002/anie.202215935

By:

Zhang, Zhongwei;
Fang, Lin;
Wang, Fei;
Deng, Yu;
Jiang, Zhengbin;
Li, Aitao

Publication type:

Article

The Crucial Role of Methodology Development in Directed Evolution of Selective Enzymes.

Published in:

Angewandte Chemie International Edition, 2020, v. 59, n. 32, p. 13204, doi. 10.1002/anie.201901491

By:

Qu, Ge;
Li, Aitao;
Acevedo‐Rocha, Carlos G.;
Sun, Zhoutong;
Reetz, Manfred T.

Publication type:

Article

Regio- and Stereoselective Steroid Hydroxylation at C7 by Cytochrome P450 Monooxygenase Mutants.

Published in:

Angewandte Chemie International Edition, 2020, v. 59, n. 30, p. 12499, doi. 10.1002/anie.202003139

By:

Aitao Li;
Acevedo-Rocha, Carlos G.;
D’Amore, Lorenzo;
Jinfeng Chen;
Yaqin Peng;
Garcia-Borràs, Marc;
Chenghua Gao;
Jinmei Zhu;
Rickerby, Harry;
Osuna, Sílvia;
Jiahai Zhou;
Reetz, Manfred T.

Publication type:

Article

Back Cover: Chemo‐ and Regioselective Dihydroxylation of Benzene to Hydroquinone Enabled by Engineered Cytochrome P450 Monooxygenase (Angew. Chem. Int. Ed. 3/2019).

Published in:

Angewandte Chemie International Edition, 2019, v. 58, n. 3, p. 918, doi. 10.1002/anie.201813834

By:

Zhou, Hangyu;
Wang, Binju;
Wang, Fei;
Yu, Xiaojuan;
Ma, Lixin;
Li, Aitao;
Reetz, Manfred T.

Publication type:

Article

Chemo‐ and Regioselective Dihydroxylation of Benzene to Hydroquinone Enabled by Engineered Cytochrome P450 Monooxygenase.

Published in:

Angewandte Chemie International Edition, 2019, v. 58, n. 3, p. 764, doi. 10.1002/anie.201812093

By:

Zhou, Hangyu;
Wang, Binju;
Wang, Fei;
Yu, Xiaojuan;
Ma, Lixin;
Li, Aitao;
Reetz, Manfred T.

Publication type:

Article

Identification, heterologous expression and characterization of a new unspecific peroxygenase from Marasmius fiardii PR-910.

Published in:

Bioresources & Bioprocessing, 2024, v. 11, n. 1, p. 1, doi. 10.1186/s40643-024-00751-x

By:

Fu, Xin;
Lin, Kexin;
Zhang, Xiaodong;
Guo, Zhiyong;
Kang, Lixin;
Li, Aitao

Publication type:

Article

Hydroxylases involved in terpenoid biosynthesis: a review.

Published in:

Bioresources & Bioprocessing, 2023, v. 10, n. 1, p. 1, doi. 10.1186/s40643-023-00656-1

By:

Zhang, Zihan;
Wu, Qing-Yang;
Ge, Yue;
Huang, Zheng-Yu;
Hong, Ran;
Li, Aitao;
Xu, Jian-He;
Yu, Hui-Lei

Publication type:

Article

Bioorthogonal catalytic nanozyme-mediated lysosomal membrane leakage for targeted drug delivery.

Published in:

Theranostics, 2022, v. 12, n. 3, p. 1132, doi. 10.7150/thno.66325

By:

Zhiyuan Sun;
Qiqi Liu;
Xinyue Wang;
Jin Wu;
Xueyan Hu;
Miaomiao Liu;
Xiangyun Zhang;
Yonghua Wei;
Zhijun Liu;
Hongjiang Liu;
Rui Chen;
Fei Wang;
Midgley, Adam C.;
Aitao Li;
Xiyun Yan;
Yanming Wang;
Jie Zhuang;
Xinglu Huang

Publication type:

Article

A redox-mediated Kemp eliminase.

Published in:

Nature Communications, 2017, v. 8, n. 3, p. 14876, doi. 10.1038/ncomms14876

By:

Li, Aitao;
Wang, Binju;
Ilie, Adriana;
Dubey, Kshatresh D.;
Bange, Gert;
Korendovych, Ivan V.;
Shaik, Sason;
Reetz, Manfred T.

Publication type:

Article

Whole-Cell-Catalyzed Multiple Regio- and Stereoselective Functionalizations in Cascade Reactions Enabled by Directed Evolution.

Published in:

Angewandte Chemie, 2016, v. 128, n. 39, p. 12205, doi. 10.1002/ange.201605990

By:

Li, Aitao;
Ilie, Adriana;
Sun, Zhoutong;
Lonsdale, Richard;
Xu, Jian ‐ He;
Reetz, Manfred T.

Publication type:

Article

A single digestion, single-stranded oligonucleotide mediated PCR-independent site-directed mutagenesis method.

Published in:

Applied Microbiology & Biotechnology, 2020, v. 104, n. 9, p. 3993, doi. 10.1007/s00253-020-10477-3

By:

Dong, Mengjie;
Wang, Fei;
Li, Qingqing;
Han, Rui;
Li, Aitao;
Zhai, Chao;
Ma, Lixin

Publication type:

Article

Boosting the efficiency of site-saturation mutagenesis for a difficult-to-randomize gene by a two-step PCR strategy.

Published in:

Applied Microbiology & Biotechnology, 2018, v. 102, n. 14, p. 6095, doi. 10.1007/s00253-018-9041-2

By:

Li, Aitao;
Acevedo-Rocha, Carlos G.;
Reetz, Manfred T.

Publication type:

Article

Multidimensional Engineering of Escherichia coli for Efficient Adipic Acid Synthesis From Cyclohexane.

Published in:

Advanced Science, 2025, v. 12, n. 14, p. 1, doi. 10.1002/advs.202411938

By:

Wang, Fei;
Sun, Huiqi;
Deng, Di;
Wu, Yuanqing;
Zhao, Jing;
Li, Qian;
Li, Aitao

Publication type:

Article

Pervasive cooperative mutational effects on multiple catalytic enzyme traits emerge via long-range conformational dynamics.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21833-w

By:

Acevedo-Rocha, Carlos G.;
Li, Aitao;
D'Amore, Lorenzo;
Hoebenreich, Sabrina;
Sanchis, Joaquin;
Lubrano, Paul;
Ferla, Matteo P.;
Garcia-Borràs, Marc;
Osuna, Sílvia;
Reetz, Manfred T.

Publication type:

Article

One-pot biocatalytic route from cycloalkanes to α,ω‐dicarboxylic acids by designed Escherichia coli consortia.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-18833-7

By:

Wang, Fei;
Zhao, Jing;
Li, Qian;
Yang, Jun;
Li, Renjie;
Min, Jian;
Yu, Xiaojuan;
Zheng, Gao-Wei;
Yu, Hui-Lei;
Zhai, Chao;
Acevedo-Rocha, Carlos G.;
Ma, Lixin;
Li, Aitao

Publication type:

Article

Bacterial cytochrome P450-catalyzed regio- and stereoselective steroid hydroxylation enabled by directed evolution and rational design.

Published in:

Bioresources & Bioprocessing, 2020, v. 7, n. 1, p. 1, doi. 10.1186/s40643-019-0290-4

By:

Zhang, Xiaodong;
Peng, Yaqin;
Zhao, Jing;
Li, Qian;
Yu, Xiaojuan;
Acevedo-Rocha, Carlos G.;
Li, Aitao

Publication type:

Article

Whole-Cell-Catalyzed Multiple Regio- and Stereoselective Functionalizations in Cascade Reactions Enabled by Directed Evolution.

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 39, p. 12026, doi. 10.1002/anie.201605990

By:

Li, Aitao;
Ilie, Adriana;
Sun, Zhoutong;
Lonsdale, Richard;
Xu, Jian-He;
Reetz, Manfred T.

Publication type:

Article

Chemical and Biocatalytic Routes to Arbutin †.

Published in:

Molecules, 2019, v. 24, n. 18, p. 3303, doi. 10.3390/molecules24183303

By:

Zhou, Hangyu;
Zhao, Jing;
Li, Aitao;
Reetz, Manfred T.

Publication type:

Article