Works by Lewis, Lionel D.

Results: 60

Pevonedistat, a Nedd8-activating enzyme inhibitor, in combination with ibrutinib in patients with relapsed/refractory B-cell non-Hodgkin lymphoma.
Published in:
Blood Cancer Journal, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41408-022-00763-w
By:
- Torka, Pallawi;
- Kambhampati, Swetha;
- Chen, Lu;
- Wang, Xiaoguang;
- Chen, Canping;
- Vuong, Dan;
- Qin, Hanjun;
- Muir, Alexandra;
- Orand, Kirsten;
- Borja, Ivana;
- Lynne Smith, D.;
- Herrera, Alex F.;
- Spurgeon, Stephen E. F.;
- Park, Byung;
- Lewis, Lionel D.;
- Hernandez-Ilizaliturri, Francisco;
- Xia, Zheng;
- Danilov, Alexey V.
Publication type:
Article
Delayed neurological sequelae from ethylene glycol, diethylene glycol and methanol poisonings.
Published in:
Clinical Toxicology (15563650), 2010, v. 48, n. 10, p. 967, doi. 10.3109/15563650.2010.532803
By:
- Reddy, Nandi J.;
- Sudini, Madhuri;
- Lewis, Lionel D.
Publication type:
Article
A phase II study of alternating sunitinib and temsirolimus therapy in patients with metastatic renal cell carcinoma.
Published in:
Cancer Medicine, 2023, v. 12, n. 12, p. 13100, doi. 10.1002/cam4.5990
By:
- Ness, Dylan B.;
- Pooler, Darcy B.;
- Ades, Steven;
- Highhouse, Brian J.;
- Labrie, Bridget M.;
- Zhou, Jie;
- Gui, Jiang;
- Lewis, Lionel D.;
- Ernstoff, Marc S.
Publication type:
Article
A phase I dose-ranging study of bendamustine and rituximab in chronic lymphocytic leukemia patients with comorbidities.
Published in:
British Journal of Haematology, 2017, v. 178, n. 5, p. 820, doi. 10.1111/bjh.14171
By:
- Danilov, Alexey V.;
- Lewis, Lionel D.;
- Lansigan, Frederick;
- Roudaia, Liya;
- Findley, Darcie L.;
- Jones, Susan Y.;
- Highhouse, Brian;
- Beaulieu, Bernard B.;
- Brown, Jennifer R.
Publication type:
Article
Agranulocytosis Associated with Lamotrigine in a Patient with Low-grade Glioma.
Published in:
Epilepsia (Series 4), 2002, v. 43, n. 2, p. 199, doi. 10.1046/j.1528-1157.2002.31801.x
By:
- Fadul, Camilo E;
- Meyer, Louise P;
- Jobst, Barbara C;
- Cornell, Cornelius J;
- Lewis, Lionel D
Publication type:
Article
Phase I study to assess the effect of adavosertib (AZD1775) on the pharmacokinetics of substrates of CYP1A2, CYP2C19, and CYP3A in patients with advanced solid tumors.
Published in:
Cancer Chemotherapy & Pharmacology, 2023, v. 92, n. 3, p. 193, doi. 10.1007/s00280-023-04554-3
By:
- Någård, Mats;
- Ah-See, Mei-Lin;
- Strauss, James;
- Wise-Draper, Trisha;
- Safran, Howard P.;
- Nadeau, Laura;
- Edenfield, William J.;
- Lewis, Lionel D.;
- Ottesen, Lone H.;
- Li, Yan;
- Mugundu, Ganesh M.
Publication type:
Article
Adavosertib (AZD1775) does not prolong the QTc interval in patients with advanced solid tumors: a phase I open-label study.
Published in:
Cancer Chemotherapy & Pharmacology, 2023, v. 92, n. 2, p. 141, doi. 10.1007/s00280-023-04555-2
By:
- Någård, Mats;
- Ah-See, Mei-Lin;
- Strauss, James;
- Wise-Draper, Trisha;
- Safran, Howard P.;
- Nadeau, Laura;
- Edenfield, William J.;
- Lewis, Lionel D.;
- Rekić, Dinko;
- Dota, Corina;
- Ottesen, Lone H.;
- Li, Yan;
- Mugundu, Ganesh M.
Publication type:
Article
Potential Impact of Pharmacogenomic Single Nucleotide Variants in a Rural Caucasian Population.
Published in:
Journal of Applied Laboratory Medicine, 2023, v. 8, n. 2, p. 251, doi. 10.1093/jalm/jfac091
By:
- Williams, Grace R;
- Tsongalis, Gregory J;
- Lewis, Lionel D;
- Barney, Rachael E;
- Cook, Leanne J;
- Aaron Geno, K;
- Nerenz, Robert D
Publication type:
Article
Clinical Validation of a 106-SNV MALDI-ToF MS Pharmacogenomic Panel.
Published in:
Journal of Applied Laboratory Medicine, 2020, v. 5, n. 3, p. 454, doi. 10.1093/jalm/jfaa018
By:
- Williams, Grace R.;
- Cook, Leanne;
- Lewis, Lionel D.;
- Tsongalis, Gregory J.;
- Nerenz, Robert D.
Publication type:
Article
Clinical and research updates on the VISTA immune checkpoint: immuno-oncology themes and highlights.
Published in:
Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1225081
By:
- Noelle, Randolph J.;
- Lines, J. Louise;
- Lewis, Lionel D.;
- Martell, Robert E.;
- Guillaudeux, Thierry;
- Lee, Sam W.;
- Mahoney, Kathleen M.;
- Vesely, Matthew D.;
- Boyd-Kirkup, Jerome;
- Nambiar, Dhanya K.;
- Scott, Andrew M.
Publication type:
Article
Editors' report, November 2011.
Published in:
British Journal of Clinical Pharmacology, 2012, v. 73, n. 2, p. 159, doi. 10.1111/j.1365-2125.2011.04148.x
By:
- Somogyi, Andrew A.;
- Lewis, Lionel D.;
- Cohen, Adam F.;
- Ferro, Albert;
- Loke, Yoon K.;
- Ritter, James M.
Publication type:
Article
Editors' pick 2011.
Published in:
British Journal of Clinical Pharmacology, 2012, v. 73, n. 1, p. 4, doi. 10.1111/j.1365-2125.2011.04144.x
By:
- Somogyi, Andrew;
- Loke, Yoon K.;
- Ferro, Albert;
- Lewis, Lionel D.;
- Cohen, Adam F.;
- Ritter, James M.
Publication type:
Article
Editors' report, November 2010.
Published in:
2011
By:
- Cohen, Adam F.;
- Loke, Yoon K.;
- Ferro, Albert;
- Lewis, Lionel D.;
- Somogy, Andrew;
- Ritter, James M.
Publication type:
Editorial
Editors' pick 2010.
Published in:
2011
By:
- Loke, Yoon K.;
- Ferro, Albert;
- Lewis, Lionel D.;
- Cohen, Adam F.;
- Somogyi, Andrew;
- Ritter, James M.
Publication type:
Editorial
Early human studies of investigational agents: dose or microdose?
Published in:
2009
By:
- Lewis, Lionel D.
Publication type:
Editorial
Editors' Report for 2006.
Published in:
2007
By:
- Aronson, Jeffrey K.;
- Cohen, Adam;
- Ritter, James M.;
- Begg, Evan J.;
- Lewis, Lionel D.;
- Schachter, Michael
Publication type:
Other
Editors’ review of 2006 and the BJCP prize.
Published in:
2007
By:
- Aronson, Jeffrey K.;
- Lennard, Martin S.;
- Ritter, James M.;
- Begg, Evan J.;
- Lewis, Lionel D.;
- Schachter, Michael
Publication type:
Other
Editors’ Report 2005.
Published in:
2006
By:
- Aronson, Jeffrey K.;
- Lennard, Martin S.;
- Ritter, James M.;
- Baber, Nigel S.;
- Begg, Evan J.;
- Lewis, Lionel D.
Publication type:
Editorial
Today's science, tomorrow's medicines.
Published in:
2006
By:
- Aronson, Jeffrey K.;
- Lennard, Martin S.;
- Ritter, James M.;
- Baber, Nigel S.;
- Begg, Evan J.;
- Lewis, Lionel D.
Publication type:
Editorial
Personalized drug therapy; the genome, the chip and the physician.
Published in:
2005
By:
- Lewis, Lionel D.
Publication type:
Editorial
Drug Delivery Systems in Cancer Therapy.
Published in:
2004
By:
- Lewis, Lionel D.
Publication type:
Book Review
A study of 5 day fractionated ifosfamide pharmacokinetics in consecutive treatment cycles.
Published in:
British Journal of Clinical Pharmacology, 1996, v. 42, n. 2, p. 179, doi. 10.1046/j.1365-2125.1996.03956.x
By:
- LEWIS, LIONEL D.
Publication type:
Article
Tumor Cell Targeting by Iron Oxide Nanoparticles Is Dominated by Different Factors In Vitro versus In Vivo.
Published in:
PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0115636
By:
- NDong, Christian;
- Tate, Jennifer A.;
- Kett, Warren C.;
- Batra, Jaya;
- Demidenko, Eugene;
- Lewis, Lionel D.;
- Hoopes, P. Jack;
- Gerngross, Tillman U.;
- Griswold, Karl E.
Publication type:
Article
Standing in the Shifting Sands of Molecular Targeting and Precision Medicine Is the Oasis of 21st-Century Oncology Therapeutics.
Published in:
Journal of Clinical Pharmacology, 2017, v. 57, p. S7, doi. 10.1002/jcph.1011
By:
- Lee, Lucy;
- Lewis, Lionel D.
Publication type:
Article
Clinical trial simulation to evaluate population pharmacokinetics and food effect: Capturing abiraterone and nilotinib exposures.
Published in:
Journal of Clinical Pharmacology, 2015, v. 55, n. 5, p. 556, doi. 10.1002/jcph.449
By:
- Li, Claire H.;
- Sherer, Eric A.;
- Lewis, Lionel D.;
- Bies, Robert R.
Publication type:
Article
1998 ASCPT workshop on Clinical Pharmacology in Primary Care Residency Education.
Published in:
Clinical Pharmacology & Therapeutics, 1997, v. 62, n. 6, p. 694, doi. 10.1016/S0009-9236(97)90091-6
By:
- Lewis, Lionel D.;
- Levey, Barbara A.
Publication type:
Article
Olsalazine and 6-mercaptopurine-related bone marrow suppression: A possible drug-drug interaction.
Published in:
Clinical Pharmacology & Therapeutics, 1997, v. 62, n. 4, p. 464, doi. 10.1016/S0009-9236(97)90125-9
By:
- Lewis, Lionel D.;
- Benin, Andrea;
- Szumlanski, Carol L.;
- Otterness, Diane M.;
- Lennard, Lynne;
- Weinshilboum, Richard M.;
- Nierenberg, David W.
Publication type:
Article
Delayed sequelae after acute overdoses or poisonings: Cranial neuropathy related to ethylene glycol ingestion.
Published in:
Clinical Pharmacology & Therapeutics, 1997, v. 61, n. 6, p. 692, doi. 10.1016/S0009-9236(97)90105-3
By:
- Lewis, Lionel D.;
- Smith, Brian W.;
- Mamourian, Alexander C.
Publication type:
Article
Tumor pharmacokinetics and pharmacodynamics of the CDK4/6 inhibitor ribociclib in patients with recurrent glioblastoma.
Published in:
Journal of Neuro-Oncology, 2019, v. 144, n. 3, p. 563, doi. 10.1007/s11060-019-03258-0
By:
- Miller, Todd W.;
- Traphagen, Nicole A.;
- Li, Jing;
- Lewis, Lionel D.;
- Lopes, Beatriz;
- Asthagiri, Ashok;
- Loomba, Johanna;
- De Jong, Jenny;
- Schiff, David;
- Patel, Sohil H.;
- Purow, Benjamin W.;
- Fadul, Camilo E.
Publication type:
Article
A phase I trial of BNC105P and ibrutinib in patients with relapsed/refractory chronic lymphocytic leukemia.
Published in:
EJHaem, 2022, v. 3, n. 4, p. 1445, doi. 10.1002/jha2.543
By:
- Pooler, Darcy B.;
- Ness, Dylan B.;
- Danilov, Alexey V.;
- Labrie, Bridget M.;
- Tosteson, Tor D.;
- Eastman, Alan;
- Lewis, Lionel D.;
- Lansigan, Frederick
Publication type:
Article
Stealth Liposomes Encapsulating a Potent ACAT1/SOAT1 Inhibitor F12511: Pharmacokinetic, Biodistribution, and Toxicity Studies in Wild-Type Mice and Efficacy Studies in Triple Transgenic Alzheimer's Disease Mice.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 13, p. 11013, doi. 10.3390/ijms241311013
By:
- De La Torre, Adrianna L.;
- Huynh, Thao N.;
- Chang, Catherine C. Y.;
- Pooler, Darcy B.;
- Ness, Dylan B.;
- Lewis, Lionel D.;
- Pannem, Sanjana;
- Feng, Yichen;
- Samkoe, Kimberley S.;
- Hickey, William F.;
- Chang, Ta Yuan
Publication type:
Article
A phase 1b study of humanized KS-interleukin-2 (huKS-IL2) immunocytokine with cyclophosphamide in patients with EpCAM-positive advanced solid tumors.
Published in:
BMC Cancer, 2013, v. 13, n. 1, p. 1, doi. 10.1186/1471-2407-13-20
By:
- Connor, Joseph P.;
- Cristea, Mihaela C.;
- Lewis, Nancy L.;
- Lewis, Lionel D.;
- Komarnitsky, Philip B.;
- Mattiacci, Maria R.;
- Felder, Mildred;
- Stewart, Sarah;
- Harter, Josephine;
- Henslee-Downey, Jean;
- Kramer, Daniel;
- Neugebauer, Roland
Publication type:
Article
A phase 1b study of humanized KS-interleukin-2 (huKS-IL2) immunocytokine with cyclophosphamide in patients with EpCAM-positive advanced solid tumors.
Published in:
2013
By:
- Connor, Joseph P;
- Cristea, Mihaela C;
- Lewis, Nancy L;
- Lewis, Lionel D;
- Komarnitsky, Philip B;
- Mattiacci, Maria R;
- Felder, Mildred;
- Stewart, Sarah;
- Harter, Josephine;
- Henslee-Downey, Jean;
- Kramer, Daniel;
- Neugebauer, Roland;
- Stupp, Roger
Publication type:
journal article
Kynurenine-Induced Aryl Hydrocarbon Receptor Signaling in Mice Causes Body Mass Gain, Liver Steatosis, and Hyperglycemia.
Published in:
2021
By:
- Rojas, Itzel Y.;
- Moyer, Benjamin J.;
- Ringelberg, Carol S.;
- Wilkins, Owen M.;
- Pooler, Darcy B.;
- Ness, Dylan B.;
- Coker, Shodeinde;
- Tosteson, Tor D.;
- Lewis, Lionel D.;
- Chamberlin, Mary D.;
- Tomlinson, Craig R.
Publication type:
journal article
Establishment of a CYP2C19 Genotyping Assay for Clinical Use.
Published in:
American Journal of Clinical Pathology, 2013, v. 139, n. 2, p. 202, doi. 10.1309/AJCP9K2KDOCPCBSV
By:
- Cervinski, Mark A.;
- Schwab, Mary C.;
- Lefferts, Joel A.;
- Lewis, Lionel D.;
- Lebel, Kimberly A.;
- Tyropolis, Allison M.;
- Pflueger, Solveig M. V.;
- Tsongalis, Gregory J.
Publication type:
Article
The effects of lapatinib on cardiac repolarization: results from a placebo controlled, single sequence, crossover study in patients with advanced solid tumors.
Published in:
2019
By:
- Coker, Shodeinde A.;
- Hurwitz, Herbert I.;
- Sharma, Sunil;
- Wang, Ding;
- Jordaan, Pierre;
- Zarate, Juan Pablo;
- Lewis, Lionel D.
Publication type:
journal article
The effects of lapatinib on CYP3A metabolism of midazolam in patients with advanced cancer.
Published in:
2017
By:
- Koch, Kevin;
- Dees, E.;
- Coker, Shodeinde;
- Reddy, Nandi;
- Gainer, Shelby;
- Arya, Nikita;
- Beelen, Andrew;
- Lewis, Lionel;
- Koch, Kevin M;
- Dees, E Claire;
- Coker, Shodeinde A;
- Reddy, Nandi J;
- Gainer, Shelby D;
- Beelen, Andrew P;
- Lewis, Lionel D
Publication type:
journal article
Pharmacokinetics and safety of vismodegib in patients with advanced solid malignancies and hepatic impairment.
Published in:
2017
By:
- Abou-Alfa, Ghassan;
- Lewis, Lionel;
- LoRusso, Patricia;
- Maitland, Michael;
- Chandra, Priya;
- Cheeti, Sravanthi;
- Colburn, Dawn;
- Williams, Sarah;
- Simmons, Brian;
- Graham, Richard;
- Abou-Alfa, Ghassan K;
- Lewis, Lionel D;
- Graham, Richard A
Publication type:
journal article
The pharmacokinetics of the bispecific antibody MDX-H210 when combined with interferon gamma-1b in a multiple-dose phase I study in patients with advanced cancer.
Published in:
Cancer Chemotherapy & Pharmacology, 2002, v. 49, n. 5, p. 375, doi. 10.1007/s00280-002-0424-8
By:
- Lewis, Lionel D.;
- Beelen, Andrew P.;
- Cole, Bernard F.;
- Wallace, Paul K.;
- Fisher, Jan L.;
- Waugh, Mary G.;
- Kaufman, Peter A.;
- Ernstoff, Marc S.
Publication type:
Article
Tumour, whole‐blood, plasma and tissue concentrations of metformin in lung cancer patients.
Published in:
British Journal of Clinical Pharmacology, 2023, v. 89, n. 3, p. 1027, doi. 10.1111/bcp.15546
By:
- Phillips, Joseph D.;
- Pooler, Darcy B.;
- Ness, Dylan B.;
- Fay, Kayla;
- Tau, Steven;
- Demidenko, Eugene;
- Hampsch, Riley A.;
- Lewis, Lionel D.;
- Miller, Todd W.
Publication type:
Article
Spotlight commentary: Navigating between financial risks and improved treatment outcomes with immune checkpoint inhibitors in cancer patients: The need for biomarker identification and dose optimization.
Published in:
British Journal of Clinical Pharmacology, 2022, v. 88, n. 12, p. 5060, doi. 10.1111/bcp.15548
By:
- Likic, Robert;
- Dear, James W.;
- Lewis, Lionel D.
Publication type:
Article
Medicamenta ad sentinam, et defectum vitae: Drugs and failure of the pump of life‐cardiotoxicity of oncotherapeutics.
Published in:
British Journal of Clinical Pharmacology, 2021, v. 87, n. 3, p. 735, doi. 10.1111/bcp.14558
By:
- Lewis, Lionel D.
Publication type:
Article
The effect of sonidegib (LDE225) on the pharmacokinetics of bupropion and warfarin in patients with advanced solid tumours.
Published in:
British Journal of Clinical Pharmacology, 2021, v. 87, n. 3, p. 1291, doi. 10.1111/bcp.14508
By:
- Pooler, Darcy B.;
- Ness, Dylan B.;
- Sarantopoulos, John;
- Squittieri, Nicholas;
- Ravichandran, Shoba;
- Britten, Carolyn D.;
- Amaravadi, Ravi K.;
- Vaishampayan, Ulka;
- LoRusso, Patricia;
- Shapiro, Geoffrey I.;
- Olszanski, Anthony J.;
- Perez, Raymond;
- Gutierrez, Martin;
- O'Rourke, Mark Allen;
- Chung, Vincent;
- Lee, James J.;
- Lewis, Lionel D.
Publication type:
Article
Taking the brake off the immune system: Hypotheses, trials, tribulations, and the evolving discipline of clinical immunopharmacology.
Published in:
British Journal of Clinical Pharmacology, 2020, v. 86, n. 9, p. 1674, doi. 10.1111/bcp.14481
By:
- Martin, Jennifer H.;
- Lewis, Lionel D.
Publication type:
Article
Effect of ketoconazole, a strong CYP3A inhibitor, on the pharmacokinetics of venetoclax, a BCL-2 inhibitor, in patients with non-Hodgkin lymphoma.
Published in:
British Journal of Clinical Pharmacology, 2017, v. 83, n. 4, p. 846, doi. 10.1111/bcp.13175
By:
- Agarwal, Suresh K.;
- Salem, Ahmed Hamed;
- Danilov, Alexey V.;
- Hu, Beibei;
- Puvvada, Soham;
- Gutierrez, Martin;
- Chien, David;
- Lewis, Lionel D.;
- Wong, Shekman L.
Publication type:
Article
Vincristine activates c-Jun N-terminal kinase in chronic lymphocytic leukaemia in vivo.
Published in:
British Journal of Clinical Pharmacology, 2015, v. 80, n. 3, p. 493, doi. 10.1111/bcp.12624
By:
- Bates, Darcy J. P.;
- Lewis, Lionel D.;
- Eastman, Alan;
- Danilov, Alexey V.
Publication type:
Article
Pharmacodynamics and pharmacokinetics of oral topotecan in patients with advanced solid tumours and impaired renal function.
Published in:
British Journal of Clinical Pharmacology, 2015, v. 80, n. 2, p. 253, doi. 10.1111/bcp.12606
By:
- Devriese, Lot A.;
- Witteveen, Petronella (Els). O.;
- Mergui‐Roelvink, Marja;
- Smith, Deborah A.;
- Lewis, Lionel D.;
- Mendelson, David S.;
- Bang, Yung‐Jue;
- Chung, Hyun Choel;
- Dar, Mohammed M.;
- Huitema, Alwin D. R.;
- Beijnen, Jos H.;
- Voest, Emile E.;
- Schellens, Jan H. M.
Publication type:
Article
Vatalanib population pharmacokinetics in patients with myelodysplastic syndrome: CALGB 10105 (Alliance).
Published in:
British Journal of Clinical Pharmacology, 2014, v. 78, n. 5, p. 1005, doi. 10.1111/bcp.12427
By:
- Wang, Xiaofeng;
- Owzar, Kouros;
- Gupta, Pankaj;
- Larson, Richard A.;
- Mulkey, Flora;
- Miller, Antonius A.;
- Lewis, Lionel D.;
- Hurd, David;
- Vij, Ravi;
- Ratain, Mark J.;
- Murry, Daryl J.
Publication type:
Article
Editors' report, November 2013.
Published in:
2014
By:
- Somogyi, Andrew A.;
- Lewis, Lionel D.;
- Cohen, Adam F.;
- Flockhart, David A.;
- Ferro, Albert;
- Loke, Yoon K.;
- Ritter, James M.
Publication type:
Editorial
Editors' pick 2013.
Published in:
British Journal of Clinical Pharmacology, 2014, v. 77, n. 2, p. 228, doi. 10.1111/bcp.12303
By:
- Ferro, Albert;
- Loke, Yoon K.;
- Lewis, Lionel D.;
- Somogyi, Andrew;
- Cohen, Adam F.;
- Ritter, James M.
Publication type:
Article