Works by Lewis, Jared C.

Results: 32

Aromatic Halogenation by Using Bifunctional Flavin Reductase-Halogenase Fusion Enzymes.

Published in:

ChemBioChem, 2017, v. 18, n. 21, p. 2099, doi. 10.1002/cbic.201700391

By:

Andorfer, Mary C.;
Belsare, Ketaki D.;
Girlich, Anna M.;
Lewis, Jared C.

Publication type:

Article

Preparation, Characterization, and Oxygenase Activity of a Photocatalytic Artificial Enzyme.

Published in:

ChemBioChem, 2015, v. 16, n. 13, p. 1880, doi. 10.1002/cbic.201500165

By:

Gu, Yifan;
Ellis‐Guardiola, Ken;
Srivastava, Poonam;
Lewis, Jared C.

Publication type:

Article

Improving the Stability and Catalyst Lifetime of the Halogenase RebH By Directed Evolution.

Published in:

ChemBioChem, 2014, v. 15, n. 9, p. 1286, doi. 10.1002/cbic.201300780

By:

Poor, Catherine B.;
Andorfer, Mary C.;
Lewis, Jared C.

Publication type:

Article

Cover Picture: A General Method for Artificial Metalloenzyme Formation through Strain-Promoted Azide-Alkyne Cycloaddition (ChemBioChem 2/2014).

Published in:

ChemBioChem, 2014, v. 15, n. 2, p. 173, doi. 10.1002/cbic.201490000

By:

Yang, Hao;
Srivastava, Poonam;
Zhang, Chen;
Lewis, Jared C.

Publication type:

Article

A General Method for Artificial Metalloenzyme Formation through Strain-Promoted Azide-Alkyne Cycloaddition.

Published in:

ChemBioChem, 2014, v. 15, n. 2, p. 223, doi. 10.1002/cbic.201300661

By:

Yang, Hao;
Srivastava, Poonam;
Zhang, Chen;
Lewis, Jared C.

Publication type:

Article

Microwave-Promoted Rhodium-Catalyzed Arylation of Heterocycles through C—H Bond ActivationThis work was supported by the NIH (grant no. GM069559, to J.A.E.) and by the Director, Office of Energy Research, Office of Basic Energy Sciences, Chemical Sciences Division, US Department of Energy (contract no. DE-AC03-76SF00098, to R.G.B.). J.Y.W. is funded by the Jean Dreyfus Boissevain Award. We gratefully acknowledge Dr. Fredrick J. Hollander and Dr. Allen G. Oliver at the UCB X-ray diffraction facility (CHEXRAY) for solving the structures of 4 a and 4 b, and Jeffrey McMahon for many helpful discussions. Dr. Wolfgang Meyer of Sasol Corp. is acknowledged for helpful advice on phobane alkylation.

Published in:

Angewandte Chemie, 2006, v. 118, n. 10, p. 1619, doi. 10.1002/ange.200504289

By:

Jared C. Lewis;
Jessica Y. Wu;
Robert G. Bergman;
Jonathan A. Ellman

Publication type:

Article

Selective C−H Halogenation of Alkenes and Alkynes Using Flavin‐Dependent Halogenases.

Published in:

Angewandte Chemie, 2024, v. 136, n. 13, p. 1, doi. 10.1002/ange.202317860

By:

Jiang, Yuhua;
Kim, Ahram;
Olive, Cahmlo;
Lewis, Jared C.

Publication type:

Article

Non‐native Intramolecular Radical Cyclization Catalyzed by a B12‐Dependent Enzyme.

Published in:

Angewandte Chemie, 2023, v. 135, n. 51, p. 1, doi. 10.1002/ange.202312893

By:

Li, Jianbin;
Kumar, Amardeep;
Lewis, Jared C.

Publication type:

Article

Directed Evolution of an Iron(II)‐ and α‐Ketoglutarate‐Dependent Dioxygenase for Site‐Selective Azidation of Unactivated Aliphatic C−H Bonds**.

Published in:

Angewandte Chemie, 2023, v. 135, n. 15, p. 1, doi. 10.1002/ange.202301370

By:

Gomez, Christian A.;
Mondal, Dibyendu;
Du, Qian;
Chan, Natalie;
Lewis, Jared C.

Publication type:

Article

The Single‐Component Flavin Reductase/Flavin‐Dependent Halogenase AetF is a Versatile Catalyst for Selective Bromination and Iodination of Arenes and Olefins.

Published in:

Angewandte Chemie, 2022, v. 134, n. 51, p. 1, doi. 10.1002/ange.202214610

By:

Jiang, Yuhua;
Snodgrass, Harrison M.;
Zubi, Yasmine S.;
Roof, Caitlin V.;
Guan, Yanfei;
Mondal, Dibyendu;
Honeycutt, Nicholas H.;
Lee, Johnny W.;
Lewis, Russell D.;
Martinez, Carlos A.;
Lewis, Jared C.

Publication type:

Article

Frontispiz: Engineering Dirhodium Artificial Metalloenzymes for Diazo Coupling Cascade Reactions.

Published in:

Angewandte Chemie, 2021, v. 133, n. 44, p. 1, doi. 10.1002/ange.202184462

By:

Upp, David M.;
Huang, Rui;
Li, Ying;
Bultman, Max J.;
Roux, Benoit;
Lewis, Jared C.

Publication type:

Article

Engineering Dirhodium Artificial Metalloenzymes for Diazo Coupling Cascade Reactions**.

Published in:

Angewandte Chemie, 2021, v. 133, n. 44, p. 23865, doi. 10.1002/ange.202107982

By:

Upp, David M.;
Huang, Rui;
Li, Ying;
Bultman, Max J.;
Roux, Benoit;
Lewis, Jared C.

Publication type:

Article

Catalytic Behavior of Mono‐N‐Protected Amino‐Acid Ligands in Ligand‐Accelerated C−H Activation by Palladium(II).

Published in:

Angewandte Chemie, 2020, v. 132, n. 27, p. 10965, doi. 10.1002/ange.202002484

By:

Salazar, Chase A.;
Gair, Joseph J.;
Flesch, Kaylin N.;
Guzei, Ilia A.;
Lewis, Jared C.;
Stahl, Shannon S.

Publication type:

Article

Metal-responsive regulation of enzyme catalysis using genetically encoded chemical switches.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29239-y

By:

Zubi, Yasmine S.;
Seki, Kosuke;
Li, Ying;
Hunt, Andrew C.;
Liu, Bingqing;
Roux, Benoît;
Jewett, Michael C.;
Lewis, Jared C.

Publication type:

Article

Flavin-dependent halogenases catalyze enantioselective olefin halocyclization.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23503-3

By:

Mondal, Dibyendu;
Fisher, Brian F.;
Jiang, Yuhua;
Lewis, Jared C.

Publication type:

Article

Selective C−H Halogenation of Alkenes and Alkynes Using Flavin‐Dependent Halogenases.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 13, p. 1, doi. 10.1002/anie.202317860

By:

Jiang, Yuhua;
Kim, Ahram;
Olive, Cahmlo;
Lewis, Jared C.

Publication type:

Article

Non‐native Intramolecular Radical Cyclization Catalyzed by a B12‐Dependent Enzyme.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 51, p. 1, doi. 10.1002/anie.202312893

By:

Li, Jianbin;
Kumar, Amardeep;
Lewis, Jared C.

Publication type:

Article

Directed Evolution of an Iron(II)‐ and α‐Ketoglutarate‐Dependent Dioxygenase for Site‐Selective Azidation of Unactivated Aliphatic C−H Bonds**.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 15, p. 1, doi. 10.1002/anie.202301370

By:

Gomez, Christian A.;
Mondal, Dibyendu;
Du, Qian;
Chan, Natalie;
Lewis, Jared C.

Publication type:

Article

The Single‐Component Flavin Reductase/Flavin‐Dependent Halogenase AetF is a Versatile Catalyst for Selective Bromination and Iodination of Arenes and Olefins.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 51, p. 1, doi. 10.1002/anie.202214610

By:

Jiang, Yuhua;
Snodgrass, Harrison M.;
Zubi, Yasmine S.;
Roof, Caitlin V.;
Guan, Yanfei;
Mondal, Dibyendu;
Honeycutt, Nicholas H.;
Lee, Johnny W.;
Lewis, Russell D.;
Martinez, Carlos A.;
Lewis, Jared C.

Publication type:

Article

Frontispiece: Engineering Dirhodium Artificial Metalloenzymes for Diazo Coupling Cascade Reactions.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 44, p. 1, doi. 10.1002/anie.202184462

By:

Upp, David M.;
Huang, Rui;
Li, Ying;
Bultman, Max J.;
Roux, Benoit;
Lewis, Jared C.

Publication type:

Article

Engineering Dirhodium Artificial Metalloenzymes for Diazo Coupling Cascade Reactions**.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 44, p. 23672, doi. 10.1002/anie.202107982

By:

Upp, David M.;
Huang, Rui;
Li, Ying;
Bultman, Max J.;
Roux, Benoit;
Lewis, Jared C.

Publication type:

Article

Catalytic Behavior of Mono‐N‐Protected Amino‐Acid Ligands in Ligand‐Accelerated C−H Activation by Palladium(II).

Published in:

Angewandte Chemie International Edition, 2020, v. 59, n. 27, p. 10873, doi. 10.1002/anie.202002484

By:

Salazar, Chase A.;
Gair, Joseph J.;
Flesch, Kaylin N.;
Guzei, Ilia A.;
Lewis, Jared C.;
Stahl, Shannon S.

Publication type:

Article

Combinatorial Alanine Substitution Enables Rapid Optimization of Cytochrome P450BM3 for Selective Hydroxylation of Large Substrates.

Published in:

ChemBioChem, 2010, v. 11, n. 18, p. 2502, doi. 10.1002/cbic.201000565

By:

Lewis, Jared C.;
Mantovani, Simone M.;
Fu, Yu;
Snow, Christopher D.;
Komor, Russell S.;
Wong, Chi-Huey;
Arnold, Frances H.

Publication type:

Article

Asymmetric catalysis by flavin‐dependent halogenases.

Published in:

Chirality, 2023, v. 35, n. 8, p. 452, doi. 10.1002/chir.23550

By:

Jiang, Yuhua;
Lewis, Jared C.

Publication type:

Article

Engineering a dirhodium artificial metalloenzyme for selective olefin cyclopropanation.

Published in:

Nature Communications, 2015, v. 6, n. 7, p. 7789, doi. 10.1038/ncomms8789

By:

Srivastava, Poonam;
Yang, Hao;
Ellis-Guardiola, Ken;
Lewis, Jared C.

Publication type:

Article

Microwave-Promoted Rhodium-Catalyzed Arylation of Heterocycles through C—H Bond ActivationThis work was supported by the NIH (grant no. GM069559, to J.A.E.) and by the Director, Office of Energy Research, Office of Basic Energy Sciences, Chemical Sciences Division, US Department of Energy (contract no. DE-AC03-76SF00098, to R.G.B.). J.Y.W. is funded by the Jean Dreyfus Boissevain Award. We gratefully acknowledge Dr. Fredrick J. Hollander and Dr. Allen G. Oliver at the UCB X-ray diffraction facility (CHEXRAY) for solving the structures of 4 a and 4 b, and Jeffrey McMahon for many helpful discussions. Dr. Wolfgang Meyer of Sasol Corp. is acknowledged for helpful advice on phobane alkylation.

Published in:

Angewandte Chemie International Edition, 2006, v. 45, n. 10, p. 1589, doi. 10.1002/anie.200504289

By:

Jared C. Lewis;
Jessica Y. Wu;
Robert G. Bergman;
Jonathan A. Ellman

Publication type:

Article

Directed Evolution of RebH for Site-Selective Halogenation of Large Biologically Active Molecules.

Published in:

Angewandte Chemie, 2015, v. 127, n. 14, p. 4300, doi. 10.1002/ange.201411901

By:

Payne, James T.;
Poor, Catherine B.;
Lewis, Jared C.

Publication type:

Article

Enantioselective Intramolecular CH Amination Catalyzed by Engineered Cytochrome P450 Enzymes In Vitro and In Vivo.

Published in:

Angewandte Chemie, 2013, v. 125, n. 35, p. 9479, doi. 10.1002/ange.201304401

By:

McIntosh, John A.;
Coelho, Pedro S.;
Farwell, Christopher C.;
Wang, Z. Jane;
Lewis, Jared C.;
Brown, Tristan R.;
Arnold, Frances H.

Publication type:

Article

Regioselective Arene Halogenation using the FAD-Dependent Halogenase RebH.

Published in:

Angewandte Chemie, 2013, v. 125, n. 20, p. 5379, doi. 10.1002/ange.201300762

By:

Payne, James T.;
Andorfer, Mary C.;
Lewis, Jared C.

Publication type:

Article

Directed Evolution of RebH for Site-Selective Halogenation of Large Biologically Active Molecules.

Published in:

Angewandte Chemie International Edition, 2015, v. 54, n. 14, p. 4226, doi. 10.1002/anie.201411901

By:

Payne, James T.;
Poor, Catherine B.;
Lewis, Jared C.

Publication type:

Article

Enantioselective Intramolecular CH Amination Catalyzed by Engineered Cytochrome P450 Enzymes In Vitro and In Vivo.

Published in:

Angewandte Chemie International Edition, 2013, v. 52, n. 35, p. 9309, doi. 10.1002/anie.201304401

By:

McIntosh, John A.;
Coelho, Pedro S.;
Farwell, Christopher C.;
Wang, Z. Jane;
Lewis, Jared C.;
Brown, Tristan R.;
Arnold, Frances H.

Publication type:

Article

Regioselective Arene Halogenation using the FAD-Dependent Halogenase RebH.

Published in:

Angewandte Chemie International Edition, 2013, v. 52, n. 20, p. 5271, doi. 10.1002/anie.201300762

By:

Payne, James T.;
Andorfer, Mary C.;
Lewis, Jared C.

Publication type:

Article

Works by Lewis, Jared C.

Aromatic Halogenation by Using Bifunctional Flavin Reductase-Halogenase Fusion Enzymes.

Preparation, Characterization, and Oxygenase Activity of a Photocatalytic Artificial Enzyme.

Improving the Stability and Catalyst Lifetime of the Halogenase RebH By Directed Evolution.

Cover Picture: A General Method for Artificial Metalloenzyme Formation through Strain-Promoted Azide-Alkyne Cycloaddition (ChemBioChem 2/2014).

A General Method for Artificial Metalloenzyme Formation through Strain-Promoted Azide-Alkyne Cycloaddition.

Selective C−H Halogenation of Alkenes and Alkynes Using Flavin‐Dependent Halogenases.

Non‐native Intramolecular Radical Cyclization Catalyzed by a B<sub>12</sub>‐Dependent Enzyme.

Directed Evolution of an Iron(II)‐ and α‐Ketoglutarate‐Dependent Dioxygenase for Site‐Selective Azidation of Unactivated Aliphatic C−H Bonds**.

The Single‐Component Flavin Reductase/Flavin‐Dependent Halogenase AetF is a Versatile Catalyst for Selective Bromination and Iodination of Arenes and Olefins.

Frontispiz: Engineering Dirhodium Artificial Metalloenzymes for Diazo Coupling Cascade Reactions.

Engineering Dirhodium Artificial Metalloenzymes for Diazo Coupling Cascade Reactions**.

Catalytic Behavior of Mono‐N‐Protected Amino‐Acid Ligands in Ligand‐Accelerated C−H Activation by Palladium(II).

Metal-responsive regulation of enzyme catalysis using genetically encoded chemical switches.

Flavin-dependent halogenases catalyze enantioselective olefin halocyclization.

Selective C−H Halogenation of Alkenes and Alkynes Using Flavin‐Dependent Halogenases.

Non‐native Intramolecular Radical Cyclization Catalyzed by a B<sub>12</sub>‐Dependent Enzyme.

Directed Evolution of an Iron(II)‐ and α‐Ketoglutarate‐Dependent Dioxygenase for Site‐Selective Azidation of Unactivated Aliphatic C−H Bonds**.

The Single‐Component Flavin Reductase/Flavin‐Dependent Halogenase AetF is a Versatile Catalyst for Selective Bromination and Iodination of Arenes and Olefins.

Frontispiece: Engineering Dirhodium Artificial Metalloenzymes for Diazo Coupling Cascade Reactions.

Engineering Dirhodium Artificial Metalloenzymes for Diazo Coupling Cascade Reactions**.

Catalytic Behavior of Mono‐N‐Protected Amino‐Acid Ligands in Ligand‐Accelerated C−H Activation by Palladium(II).

Combinatorial Alanine Substitution Enables Rapid Optimization of Cytochrome P450<sub>BM3</sub> for Selective Hydroxylation of Large Substrates.

Asymmetric catalysis by flavin‐dependent halogenases.

Engineering a dirhodium artificial metalloenzyme for selective olefin cyclopropanation.

Directed Evolution of RebH for Site-Selective Halogenation of Large Biologically Active Molecules.

Enantioselective Intramolecular CH Amination Catalyzed by Engineered Cytochrome P450 Enzymes In Vitro and In Vivo.

Regioselective Arene Halogenation using the FAD-Dependent Halogenase RebH.

Directed Evolution of RebH for Site-Selective Halogenation of Large Biologically Active Molecules.

Enantioselective Intramolecular CH Amination Catalyzed by Engineered Cytochrome P450 Enzymes In Vitro and In Vivo.

Regioselective Arene Halogenation using the FAD-Dependent Halogenase RebH.