Works by Lewerenz, Jan

Results: 44

Activation of stimulatory heterotrimeric G proteins increases glutathione and protects neuronal cells against oxidative stress.
Published in:
Journal of Neurochemistry, 2003, v. 87, n. 2, p. 522, doi. 10.1046/j.1471-4159.2003.02019.x
By:
- Lewerenz, Jan;
- Letz, Julia;
- Methner, Axel
Publication type:
Article
Decreased IL-8 levels in CSF and serum of AD patients and negative correlation of MMSE and IL-1β.
Published in:
BMC Neurology, 2016, v. 16, p. 1, doi. 10.1186/s12883-016-0707-z
By:
- Hesse, Raphael;
- Wahler, Anke;
- Gummert, Pauline;
- Kirschmer, Stefanie;
- Otto, Markus;
- Tumani, Hayrettin;
- Lewerenz, Jan;
- Schnack, Cathrin;
- von Arnim, Christine A. F.
Publication type:
Article
Lesion of the dorsorostral midbrain sparing the nigrostriatal tract mimics axial rigidity seen in progressive supranuclear palsy.
Published in:
Movement Disorders, 2005, v. 20, n. 8, p. 1071, doi. 10.1002/mds.20484
By:
- Lewerenz, Jan;
- Zurowski, Bartosz;
- Jenicke, Lars;
- Bäumer, Tobias;
- Lees, Andrew J.;
- Münchau, Alexander
Publication type:
Article
Krankheitsmodifizierende Therapieansätze bei der Huntington-Krankheit: Blicke zurück und Blicke voraus.
Published in:
Der Nervenarzt, 2022, v. 93, n. 2, p. 179, doi. 10.1007/s00115-021-01224-8
By:
- Frank, Wiebke;
- Lindenberg, Katrin S.;
- Mühlbäck, Alzbeta;
- Lewerenz, Jan;
- Landwehrmeyer, G. Bernhard
Publication type:
Article
Tick-Borne Encephalitis: A Differential Pattern of Intrathecal Humoral Immune Response and Inflammatory Cell Composition Compared with Other Viral CNS Infections.
Published in:
Cells (2073-4409), 2020, v. 9, n. 10, p. 2169, doi. 10.3390/cells9102169
By:
- Senel, Makbule;
- Rapp, Daniel;
- Mayer, Benjamin;
- Jesse, Sarah;
- Süssmuth, Sigurd D.;
- Otto, Markus;
- Lewerenz, Jan;
- Tumani, Hayrettin
Publication type:
Article
Charcot–Marie–Tooth disease CMT4A: GDAP1 increases cellular glutathione and the mitochondrial membrane potential.
Published in:
Human Molecular Genetics, 2012, v. 21, n. 1, p. 150, doi. 10.1093/hmg/ddr450
By:
- Noack, Rebecca;
- Frede, Svenja;
- Albrecht, Philipp;
- Henke, Nadine;
- Pfeiffer, Annika;
- Knoll, Katrin;
- Dehmel, Thomas;
- Meyer zu Hörste, Gerd;
- Stettner, Mark;
- Kieseier, Bernd C.;
- Summer, Holger;
- Golz, Stefan;
- Kochanski, Andrzej;
- Wiedau-Pazos, Martina;
- Arnold, Susanne;
- Lewerenz, Jan;
- Methner, Axel
Publication type:
Article
A 64‐Year‐Old Patient With a Mesiotemporal Mass and Symptomatic Epilepsy.
Published in:
Brain Pathology, 2020, v. 30, n. 2, p. 413, doi. 10.1111/bpa.12818
By:
- Kuehn, Julia C.;
- Scheuerle, Angelika;
- Bauer, Jan;
- Becker, Albert J.;
- Wirtz, Rainer;
- Lewerenz, Jan
Publication type:
Article
Effects of dimethyl fumarate on neuroprotection and immunomodulation.
Published in:
Journal of Neuroinflammation, 2012, v. 9, n. 1, p. 163, doi. 10.1186/1742-2094-9-163
By:
- Albrecht, Philipp;
- Bouchachia, Imane;
- Goebels, Norbert;
- Henke, Nadine;
- Hofstetter, Harald H.;
- Issberner, Andrea;
- Kovacs, Zsuzsa;
- Lewerenz, Jan;
- Lisak, Dmitrij;
- Maher, Pamela;
- Mausberg, Anne-Kathrin;
- Quasthoff, Kim;
- Zimmermann, Corinna;
- Hartung, Hans-Peter;
- Methner, Axel
Publication type:
Article
Cerebrospinal Fluid Findings in Patients With Autoimmune Encephalitis—A Systematic Analysis.
Published in:
Frontiers in Neurology, 2019, p. 1, doi. 10.3389/fneur.2019.00804
By:
- Blinder, Tetyana;
- Lewerenz, Jan
Publication type:
Article
Development of an algorithm for identifying paraneoplastic ischemic stroke in association with lung, pancreatic, and colorectal cancer.
Published in:
Therapeutic Advances in Neurological Disorders, 2024, p. 1, doi. 10.1177/17562864241239123
By:
- Kassubek, Rebecca;
- Winter, Marc-Andre G. R.;
- Dreyhaupt, Jens;
- Laible, Mona;
- Kassubek, Jan;
- Ludolph, Albert C.;
- Lewerenz, Jan
Publication type:
Article
Development of an algorithm for identifying paraneoplastic ischemic stroke in association with lung, pancreatic, and colorectal cancer.
Published in:
Therapeutic Advances in Neurological Disorders, 2024, v. 17, p. 1, doi. 10.1177/17562864241239123
By:
- Kassubek, Rebecca;
- Winter, Marc-Andre G. R.;
- Dreyhaupt, Jens;
- Laible, Mona;
- Kassubek, Jan;
- Ludolph, Albert C.;
- Lewerenz, Jan
Publication type:
Article
Mechanismen und Bedeutung der oxidativen Glutamattoxizität.
Published in:
Neuroforum, 2006, v. 12, n. 3, p. 222, doi. 10.1515/nf-2006-0303
By:
- Lewerenz, Jan;
- Methner, Axel
Publication type:
Article
Genetic predisposition in anti-LGI1 and anti-NMDA receptor encephalitis.
Published in:
2018
By:
- Mueller, Stefanie H.;
- Färber, Anna;
- Prüss, Harald;
- Melzer, Nico;
- Golombeck, Kristin S.;
- Kümpfel, Tania;
- Thaler, Franziska;
- Elisak, Martin;
- Lewerenz, Jan;
- Kaufmann, Max;
- Sühs, Kurt‐Wolfram;
- Ringelstein, Marius;
- Kellinghaus, Christoph;
- Bien, Christian G.;
- Kraft, Andrea;
- Zettl, Uwe K.;
- Ehrlich, Sven;
- Handreka, Robert;
- Rostásy, Kevin;
- Then Bergh, Florian
Publication type:
journal article
Main path and byways: non-vesicular glutamate release by system xc- as an important modifier of glutamatergic neurotransmission.
Published in:
Journal of Neurochemistry, 2015, v. 135, n. 6, p. 1062, doi. 10.1111/jnc.13348
By:
- Massie, Ann;
- Boillée, Séverine;
- Hewett, Sandra;
- Knackstedt, Lori;
- Lewerenz, Jan
Publication type:
Article
Lactacidosis modulates glutathione metabolism and oxidative glutamate toxicity.
Published in:
Journal of Neurochemistry, 2010, v. 113, n. 2, p. 502, doi. 10.1111/j.1471-4159.2010.06621.x
By:
- Lewerenz, Jan;
- Dargusch, Richard;
- Maher, Pamela
Publication type:
Article
Induction of Nrf2 and xCT are involved in the action of the neuroprotective antibiotic ceftriaxone in vitro.
Published in:
Journal of Neurochemistry, 2009, v. 111, n. 2, p. 332, doi. 10.1111/j.1471-4159.2009.06347.x
By:
- Lewerenz, Jan;
- Albrecht, Philipp;
- Tien, Mai-Ly Tran;
- Henke, Nadine;
- Karumbayaram, Saravanan;
- Kornblum, Harley I.;
- Wiedau-Pazos, Martina;
- Schubert, Dave;
- Maher, Pamela;
- Methner, Axel
Publication type:
Article
Nitroxyl exacerbates ischemic cerebral injury and oxidative neurotoxicity.
Published in:
Journal of Neurochemistry, 2009, v. 110, n. 6, p. 1766, doi. 10.1111/j.1471-4159.2009.06266.x
By:
- Chi-un Choe;
- Lewerenz, Jan;
- Fischer, Gerry;
- Uliasz, Tracy F.;
- Espey, Michael Graham;
- Hummel, Friedhelm C.;
- King, Stephen Bruce;
- Schwedhelm, Edzard;
- Böger, Rainer H.;
- Gerloff, Christian;
- Hewett, Sandra J.;
- Magnus, Tim;
- Donzelli, Sonia
Publication type:
Article
A novel approach to enhancing cellular glutathione levels.
Published in:
Journal of Neurochemistry, 2008, v. 107, n. 3, p. 690, doi. 10.1111/j.1471-4159.2008.05620.x
By:
- Maher, Pamela;
- Lewerenz, Jan;
- Lozano, Carles;
- Torres, Josep Lluís
Publication type:
Article
Cooperative action of glutamate transporters and cystine/glutamate antiporter system Xc– protects from oxidative glutamate toxicity.
Published in:
Journal of Neurochemistry, 2006, v. 98, n. 3, p. 916, doi. 10.1111/j.1471-4159.2006.03921.x
By:
- Lewerenz, Jan;
- Klein, Mathias;
- Methner, Axel
Publication type:
Article
Clinical associations and characteristics of the polyspecific intrathecal immune response in elderly patients with non-multiple sclerosis chronic autoimmune-inflammatory neurological diseases - a retrospective cross-sectional study.
Published in:
Frontiers in Neurology, 2023, p. 1, doi. 10.3389/fneur.2023.1193015
By:
- Brauchle, Felix;
- Rapp, Daniel;
- Senel, Makbule;
- Huss, André;
- Dreyhaupt, Jens;
- Klose, Veronika;
- Süße, Marie;
- Stürner, Klarissa Hanja;
- Leypoldt, Frank;
- Tumani, Hayrettin;
- Lewerenz, Jan
Publication type:
Article
CSF oligoclonal IgG bands are not associated with ALS progression and prognosis.
Published in:
Frontiers in Neurology, 2023, p. 1, doi. 10.3389/fneur.2023.1170360
By:
- Klose, Veronika;
- Jesse, Sarah;
- Lewerenz, Jan;
- Kassubek, Jan;
- Dorst, Johannes;
- Tumani, Hayrettin;
- Ludolph, Albert C.;
- Roselli, Francesco
Publication type:
Article
Chronic Glutamate Toxicity in Neurodegenerative Diseases--What is the Evidence?
Published in:
Frontiers in Neuroscience, 2015, p. 1, doi. 10.3389/fnins.2015.00469
By:
- Lewerenz, Jan;
- Maher, Pamela;
- Freire, Marco Aurelio M.;
- Vickers, James C.
Publication type:
Article
Blood–CSF barrier integrity in amyotrophic lateral sclerosis.
Published in:
Brain: A Journal of Neurology, 2024, v. 147, n. 12, p. 4254, doi. 10.1093/brain/awae144
By:
- Klose, Veronika;
- Jesse, Sarah;
- Lewerenz, Jan;
- Kassubek, Jan;
- Dorst, Johannes;
- Rosenbohm, Angela;
- Nagel, Gabriele;
- Wernecke, Deborah;
- Roselli, Francesco;
- Tumani, Hayrettin;
- Ludolph, Albert C
Publication type:
Article
Clinical, serological and genetic predictors of response to immunotherapy in anti-IgLON5 disease.
Published in:
Brain: A Journal of Neurology, 2023, v. 146, n. 2, p. 600, doi. 10.1093/brain/awac090
By:
- Grüter, Thomas;
- Möllers, Franziska E;
- Tietz, Anja;
- Dargvainiene, Justina;
- Melzer, Nico;
- Heidbreder, Anna;
- Strippel, Christine;
- Kraft, Andrea;
- Höftberger, Romana;
- Schöberl, Florian;
- Thaler, Franziska S;
- Wickel, Jonathan;
- Chung, Ha-Yeun;
- Seifert, Frank;
- Tschernatsch, Marlene;
- Nagel, Michael;
- Lewerenz, Jan;
- Jarius, Sven;
- Wildemann, Brigitte C;
- Azevedo, Lucie de
Publication type:
Article
The flavonoid fisetin attenuates postischemic immune cell infiltration, activation and infarct size after transient cerebral middle artery occlusion in mice.
Published in:
Journal of Cerebral Blood Flow & Metabolism, 2012, v. 32, n. 5, p. 835, doi. 10.1038/jcbfm.2011.189
By:
- Gelderblom, Mathias;
- Leypoldt, Frank;
- Lewerenz, Jan;
- Birkenmayer, Gabriel;
- Orozco, Denise;
- Ludewig, Peter;
- Thundyil, John;
- Arumugam, Thiruma V;
- Gerloff, Christian;
- Tolosa, Eva;
- Maher, Pamela;
- Magnus, Tim
Publication type:
Article
Absence of system xc- on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis.
Published in:
2017
By:
- Merckx, Ellen;
- Albertini, Giulia;
- Paterka, Magdalena;
- Jensen, Cathy;
- Albrecht, Philipp;
- Dietrich, Michael;
- Van Liefferinge, Joeri;
- Bentea, Eduard;
- Verbruggen, Lise;
- Demuyser, Thomas;
- Deneyer, Lauren;
- Lewerenz, Jan;
- van Loo, Geert;
- De Keyser, Jacques;
- Sato, Hideyo;
- Maher, Pamela;
- Methner, Axel;
- Massie, Ann
Publication type:
journal article
CSF Free Light Chains as a Marker of Intrathecal Immunoglobulin Synthesis in Multiple Sclerosis: A Blood-CSF Barrier Related Evaluation in a Large Cohort.
Published in:
Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00641
By:
- Senel, Makbule;
- Mojib-Yezdani, Fatemeh;
- Braisch, Ulrike;
- Bachhuber, Franziska;
- Lewerenz, Jan;
- Ludolph, Albert C.;
- Otto, Markus;
- Tumani, Hayrettin
Publication type:
Article
Bevacizumab in temozolomide refractory high-grade gliomas: single-centre experience and review of the literature.
Published in:
Therapeutic Advances in Neurological Disorders, 2018, v. 11, p. 1, doi. 10.1177/1756285617753597
By:
- Jeck, Jennifer;
- Kassubek, Rebecca;
- Coburger, Jan;
- Edenhofer, Simone;
- Schönsteiner, Stefan S.;
- Ludolph, Albert C.;
- Schmitz, Bernd;
- Engelke, Jens;
- Mayer-Steinacker, Regine;
- Lewerenz, Jan;
- Bullinger, Lars
Publication type:
Article
Oxytosis/Ferroptosis-(Re-) Emerging Roles for Oxidative Stress-Dependent Non-apoptotic Cell Death in Diseases of the Central Nervous System.
Published in:
Frontiers in Neuroscience, 2018, p. 1, doi. 10.3389/fnins.2018.00214
By:
- Lewerenz, Jan;
- Ates, Gamze;
- Methner, Axel;
- Conrad, Marcus;
- Maher, Pamela
Publication type:
Article
Long latency between GAD-antibody detection and development of limbic encephalitis--a case report.
Published in:
2015
By:
- Fauser, Susanne;
- Uttner, Ingo;
- Ariño, Helena;
- Scherbaum, Werner A.;
- Saiz, Albert;
- Lewerenz, Jan
Publication type:
journal article
[18F]DPA-714-PET-MRI reveals pronounced innate immunity in human anti-LGI1 and anti-CASPR2 limbic encephalitis.
Published in:
Journal of Neurology, 2024, v. 271, n. 6, p. 3653, doi. 10.1007/s00415-024-12302-7
By:
- Roll, Wolfgang;
- Bauer, Jan;
- Dik, Andre;
- Mueller, Christoph;
- Backhaus, Philipp;
- Räuber, Saskia;
- Zinnhardt, Bastian;
- Gallus, Marco;
- Wimberley, Catriona;
- Körtvelyessy, Peter;
- Schindler, Philipp;
- Stenzel, Werner;
- Elger, Christian E.;
- Becker, Albert;
- Lewerenz, Jan;
- Wiendl, Heinz;
- Meuth, Sven G.;
- Schäfers, Michael;
- Melzer, Nico
Publication type:
Article
Different pain phenotypes are associated with anti-Caspr2 autoantibodies.
Published in:
Journal of Neurology, 2024, v. 271, n. 5, p. 2736, doi. 10.1007/s00415-024-12224-4
By:
- Greguletz, Patrik;
- Plötz, Maria;
- Baade-Büttner, Carolin;
- Bien, Christian G.;
- Eisenhut, Katharina;
- Geis, Christian;
- Handreka, Robert;
- Klausewitz, Jaqueline;
- Körtvelyessy, Peter;
- Kovac, Stjepana;
- Kraft, Andrea;
- Lewerenz, Jan;
- Malter, Michael;
- Nagel, Michael;
- von Podewils, Felix;
- Prüß, Harald;
- Rada, Anna;
- Rau, Johanna;
- Rauer, Sebastian;
- Rößling, Rosa
Publication type:
Article
Cerebrospinal fluid levels of proenkephalin and prodynorphin are differentially altered in Huntington's and Parkinson's disease.
Published in:
Journal of Neurology, 2022, v. 269, n. 9, p. 5136, doi. 10.1007/s00415-022-11187-8
By:
- Barschke, Peggy;
- Abu-Rumeileh, Samir;
- Al Shweiki, M. H. D. Rami;
- Barba, Lorenzo;
- Paolini Paoletti, Federico;
- Oeckl, Patrick;
- Steinacker, Petra;
- Halbgebauer, Steffen;
- Gaetani, Lorenzo;
- Lewerenz, Jan;
- Ludolph, Albert Christian;
- Landwehrmeyer, Georg Bernhard;
- Parnetti, Lucilla;
- Otto, Markus
Publication type:
Article
Admission diagnoses of patients later diagnosed with autoimmune encephalitis.
Published in:
Journal of Neurology, 2019, v. 266, n. 1, p. 124, doi. 10.1007/s00415-018-9105-3
By:
- Baumgartner, Annette;
- Rauer, Sebastian;
- Hottenrott, Tilman;
- Leypoldt, Frank;
- Ufer, Friederike;
- Hegen, Harald;
- Prüss, Harald;
- Lewerenz, Jan;
- Deisenhammer, Florian;
- Stich, Oliver
Publication type:
Article
Identifying ischemic stroke associated with cancer: a multiple model derived from a case-control analysis.
Published in:
Journal of Neurology, 2017, v. 264, n. 4, p. 781, doi. 10.1007/s00415-017-8432-0
By:
- Kassubek, Rebecca;
- Bullinger, Lars;
- Kassubek, Jan;
- Dreyhaupt, Jens;
- Ludolph, Albert;
- Althaus, Katharina;
- Lewerenz, Jan
Publication type:
Article
Induction of Bcl-2 by functional regulation of G-protein coupled receptors protects from oxidative glutamate toxicity by increasing glutathione
Published in:
Free Radical Research, 2006, v. 40, n. 11, p. 1113, doi. 10.1080/10715760600838191
By:
- Sahin, Mert;
- Saxena, Ambrish;
- Joost, Patrick;
- Lewerenz, Jan;
- Methner, Axel
Publication type:
Article
Mitochondrial function and energy metabolism in neuronal HT22 cells resistant to oxidative stress.
Published in:
British Journal of Pharmacology, 2014, v. 171, n. 8, p. 2147, doi. 10.1111/bph.12549
By:
- Pfeiffer, Annika;
- Jaeckel, Martin;
- Lewerenz, Jan;
- Noack, Rebecca;
- Pouya, Alireza;
- Schacht, Teresa;
- Hoffmann, Christina;
- Winter, Jennifer;
- Schweiger, Susann;
- Schäfer, Michael K E;
- Methner, Axel
Publication type:
Article
Regulation of xCT expression and system function in neuronal cells.
Published in:
Amino Acids, 2012, v. 42, n. 1, p. 171, doi. 10.1007/s00726-011-0862-x
By:
- Lewerenz, Jan;
- Maher, Pamela;
- Methner, Axel
Publication type:
Article
Ubiquitination and the proteasome rather than caspase‐3‐mediated C‐terminal cleavage are involved in the EAAT2 degradation by staurosporine‐induced cellular stress.
Published in:
Journal of Neurochemistry, 2021, v. 157, n. 4, p. 1284, doi. 10.1111/jnc.15237
By:
- Voss, Timo‐Daniel;
- Gerget, Maria;
- Linkus, Birgit;
- Einem, Bjoern;
- Landwehrmeyer, G. Bernhard;
- Lewerenz, Jan
Publication type:
Article
Das NF1‐Mikrodeletions‐Syndrom: Die frühzeitige genetische Diagnose erleichtert den Umgang mit einer klinisch definierten Erkrankung.
Published in:
Journal der Deutschen Dermatologischen Gesellschaft, 2022, v. 20, n. 3, p. 273, doi. 10.1111/ddg.14707_g
By:
- Kehrer‐Sawatzki, Hildegard;
- Bäzner, Ute;
- Krämer, Johannes;
- Lewerenz, Jan;
- Pfeiffer, Christiane
Publication type:
Article
The NF1 microdeletion syndrome: early genetic diagnosis facilitates the management of a clinically defined disease.
Published in:
Journal der Deutschen Dermatologischen Gesellschaft, 2022, v. 20, n. 3, p. 273, doi. 10.1111/ddg.14707
By:
- Kehrer‐Sawatzki, Hildegard;
- Bäzner, Ute;
- Krämer, Johannes;
- Lewerenz, Jan;
- Pfeiffer, Christiane
Publication type:
Article
Cerebrospinal Fluid Levels of Prodynorphin‐Derived Peptides are Decreased in Huntington's Disease.
Published in:
Movement Disorders, 2021, v. 36, n. 2, p. 492, doi. 10.1002/mds.28300
By:
- Al Shweiki, MHD Rami;
- Oeckl, Patrick;
- Pachollek, Adrian;
- Steinacker, Petra;
- Barschke, Peggy;
- Halbgebauer, Steffen;
- Anderl‐Straub, Sarah;
- Lewerenz, Jan;
- Ludolph, Albert C.;
- Bernhard Landwehrmeyer, Georg;
- Otto, Markus
Publication type:
Article
Fumaric Acid Esters Stimulate Astrocytic VEGF Expression through HIF-1α and Nrf2.
Published in:
PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0076670
By:
- Wiesner, Diana;
- Merdian, Irma;
- Lewerenz, Jan;
- Ludolph, Albert C.;
- Dupuis, Luc;
- Witting, Anke
Publication type:
Article
p62, Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects.
Published in:
Autophagy, 2011, v. 7, n. 6, p. 572, doi. 10.4161/auto.7.6.14943
By:
- Bartlett, Bryan J.;
- Isakson, Pauline;
- Lewerenz, Jan;
- Sanchez, Heriberto;
- Kotzebue, Roxanne W.;
- Cumming, Robert;
- Harris, Greg L.;
- Nezis, Ioannis P.;
- Schubert, David;
- Simonsen, Anne;
- Finley, Kim D.
Publication type:
Article