Works by Levy, David E

Results: 49

Functional Crosstalk between Type I and II Interferon through the Regulated Expression of STAT1.

Published in:

PLoS Biology, 2010, v. 8, n. 5, p. 1, doi. 10.1371/journal.pbio.1000361

By:

Gough, Daniel J.;
Messina, Nicole L.;
Hii, Linda;
Gould, Jodee A.;
Sabapathy, Kanaga;
Robertson, Ashley P. S.;
Trapani, Joseph A.;
Levy, David E.;
Hertzog, Paul J.;
Clarke, Christopher J. P.;
Johnstone, Ricky W.

Publication type:

Article

Functional Crosstalk between Type I and II Interferon through the Regulated Expression of STAT1.

Published in:

PLoS Biology, 2010, v. 8, n. 4, p. 1, doi. 10.1371/journal.pbio.1000361

By:

Gough, Daniel J.;
Messina, Nicole L.;
Hii, Linda;
Gould, Jodee A.;
Kanaga6Sabapathy;
Robertson, Ashley P. S.;
Trapani, Joseph A.;
Levy, David E.;
Hertzog, Paul J.;
Clarke, Christopher J. P.;
Johnstone, Ricky W.

Publication type:

Article

IL-6 programs T<sub>H</sub>-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways.

Published in:

Nature Immunology, 2007, v. 8, n. 9, p. 967, doi. 10.1038/ni1488

By:

Zhou, Liang;
Ivanov, Ivaylo I;
Spolski, Rosanne;
Min, Roy;
Shenderov, Kevin;
Egawa, Takeshi;
Levy, David E;
Leonard, Warren J;
Littman, Dan R

Publication type:

Article

RIGging an antiviral defense-it's in the CARDs.

Published in:

Nature Immunology, 2004, v. 5, n. 7, p. 699, doi. 10.1038/ni0704-699

By:

Levy, David E.;
Marie, Isabelle I.

Publication type:

Article

Intravenous Ancrod for Treatment of Acute Ischemic Stroke.

Published in:

JAMA: Journal of the American Medical Association, 2000, v. 283, n. 18, p. 2395, doi. 10.1001/jama.283.18.2395

By:

Sherman, David G.;
Atkinson, Richard P.;
Chippendale, Thomas;
Levine, Kenneth A.;
Ng, Ken;
Futrell, Nancy;
Hsu, Chung Y.;
Levy, David E.

Publication type:

Article

Mitochondrial STAT3 regulates antioxidant gene expression through complex I‐derived NAD in triple negative breast cancer.

Published in:

Molecular Oncology, 2021, v. 15, n. 5, p. 1432, doi. 10.1002/1878-0261.12928

By:

Lahiri, Tanaya;
Brambilla, Lara;
Andrade, Joshua;
Askenazi, Manor;
Ueberheide, Beatrix;
Levy, David E.

Publication type:

Article

Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression.

Published in:

EMBO Journal, 2001, v. 20, n. 1/2, p. 91, doi. 10.1093/emboj/20.1.91

By:

Kovarik, Pavel;
Mangold, Monika;
Ramsauer, Katrin;
Heidari, Hamid;
Steinborn, Ralf;
Zotter, Angelika;
Levy, David E.;
Müller, Mathias;
Decker, Thomas

Publication type:

Article

Differential viral induction of distinct interferon-a genes by positive feedback through interferon regulatory factor-7.

Published in:

EMBO Journal, 1998, v. 17, n. 22, p. 6660, doi. 10.1093/emboj/17.22.6660

By:

Marie, Isabelle;
Durbin, Joan e.;
Levy, David E.

Publication type:

Article

The Cyclin-Dependent Kinase 8 (CDK8) Inhibitor DCA Promotes a Tolerogenic Chemical Immunophenotype in CD4<sup>+</sup> T Cells via a Novel CDK8-GATA3-FOXP3 Pathway.

Published in:

Molecular & Cellular Biology, 2021, v. 41, n. 9, p. 1, doi. 10.1128/MCB.00085-21

By:

Arnett, Azlann;
Moo, Keagan G.;
Flynn, Kaitlin J.;
Sundberg, Thomas B.;
Johannessen, Liv;
Shamji, Alykhan F.;
Gray, Nathanael S.;
Decker, Thomas;
Ye Zheng;
Gersuk, Vivian H.;
Rahman, Ziaur S.;
Levy, David E.;
Marié, Isabelle J.;
Linsley, Peter S.;
Xavier, Ramnik J.;
Khor, Bernard

Publication type:

Article

Signalling: Stats: transcriptional control and biological impact.

Published in:

Nature Reviews Molecular Cell Biology, 2002, v. 3, n. 9, p. 651, doi. 10.1038/nrm909

By:

Levy, David E.;
Darnell, J. E.

Publication type:

Article

Cost-effectiveness of ancrod treatment of acute ischaemic stroke: results from the Stroke Treatment with Ancrod Trial (STAT)

Published in:

2002

By:

Samsa, Gregory P;
Matchar, David B;
Williams, G Rhys;
Levy, David E

Publication type:

Journal Article

Cost-effectiveness of ancrod treatment of acute ischaemic stroke: results from the Stroke Treatment with Ancrod Trial (STAT).

Published in:

Journal of Evaluation in Clinical Practice, 2002, v. 8, n. 1, p. 61, doi. 10.1046/j.1365-2753.2002.00315.x

By:

PhD, Gregory P. Samsa;
MD, David B. Matchar;
ScD, G. Rhys Williams;
MD, David E. Levy

Publication type:

Article

Adjusting for Energy Efficiency in Residential Appraisal.

Published in:

Appraisal Journal, 1987, v. 55, n. 3, p. 457

By:

Levy, David E.

Publication type:

Article

Tonic interferon restricts pathogenic IL-17-driven inflammatory disease via balancing the microbiome.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.68371

By:

Marié, Isabelle J.;
Brambilla, Lara;
Azzouz, Doua;
Ze Chen;
Baracho, Gisele V.;
Arnett, Azlann;
Li, Haiyan S.;
Weiguo Liu;
Cimmino, Luisa;
Chattopadhyay, Pratip;
Silverman, Gregg;
Watowich, Stephanie S.;
Khor, Bernard;
Levy, David E.

Publication type:

Article

Signal transduction pathway activating interferon-alpha-stimulated gene expression.

Published in:

British Journal of Haematology, 1991, v. 79, p. 9, doi. 10.1111/j.1365-2141.1991.tb08110.x

By:

Veals, Susan A.;
Kessler, Daniel S.;
Josiah, Serene;
Leonard, DebraG. B.;
Levy, David E.

Publication type:

Article

Reply.

Published in:

Annals of Neurology, 1988, v. 24, n. 2, p. 288, doi. 10.1002/ana.410240226

By:

Levy, David E.;
Tramo, Marchk J.;
Plum, Fred

Publication type:

Article

Differences in cerebral blood flow and glucose utilization in vegetative versus locked-in patients.

Published in:

1987

By:

Levy, David E.;
Sidtis, John J.;
Rottenberg, David A.;
Jarden, Jens O.;
Strother, Stephen C.;
Dhawan, Vijay;
Ginos, James Z.;
Tramo, Mark J.;
Evans, Alan C.;
Plum, Fred;
Levy, D E;
Sidtis, J J;
Rottenberg, D A;
Jarden, J O;
Strother, S C;
Dhawan, V;
Ginos, J Z;
Tramo, M J;
Evans, A C;
Plum, F

Publication type:

journal article

Interferon-γ-induced inhibition of neuronal vesicular stomatitis virus infection is STAT1 dependent.

Published in:

Journal of NeuroVirology, 2004, v. 10, n. 1, p. 57, doi. 10.1080/13550280490261707

By:

Chesler, David A.;
Dodard, Cindy;
Lee, Grace Y.;
Levy, David E.;
Reiss, Carol Shoshkes

Publication type:

Article

New and Old Functions of STAT3.

Published in:

Cell Cycle, 2005, v. 4, n. 9, p. 1131, doi. 10.4161/cc.4.9.1985

By:

Inghirami, Giorgio;
Chiarle, Roberto;
Simmons, William J.;
Piva, Roberto;
Schlessinger, Karni;
Levy, David E.

Publication type:

Article

Regulation of Stat3 transcriptional activity by the conserved LPMSP motif for OSM and IL-6 signaling

Published in:

FEBS Letters, 2006, v. 580, n. 25, p. 5880, doi. 10.1016/j.febslet.2006.09.054

By:

Sun, Wei;
Snyder, Marylynn;
Levy, David E.;
Zhang, J. Jillian

Publication type:

Article

A Synthetic Lethal Interaction between Glutathione Synthesis and Mitochondrial Reactive Oxygen Species Provides a Tumor-Specific Vulnerability Dependent on STAT3.

Published in:

Molecular & Cellular Biology, 2015, v. 35, n. 21, p. 3646, doi. 10.1128/MCB.00541-15

By:

Garama, Daniel J.;
Harris, Tiffany J.;
White, Christine L.;
Rossello, Fernando J.;
Abdul-Hay, Maher;
Gough, Daniel J.;
Levy, David E.

Publication type:

Article

The Human RVB Complex Is Required for Efficient Transcription of Type I Interferon-Stimulated Genes.

Published in:

Molecular & Cellular Biology, 2013, v. 33, n. 19, p. 3817, doi. 10.1128/MCB.01562-12

By:

Gnatovskiy, Leonid;
Mita, Paolo;
Levy, David E.

Publication type:

Article

Contribution of a TANK-Binding Kinase 1"Interferon (IFN) Regulatory Factor 7 Pathway to IFN-γ-Induced Gene Expression.

Published in:

Molecular & Cellular Biology, 2012, v. 32, n. 6, p. 1032, doi. 10.1128/MCB.06021-11

By:

Farlik, Matthias;
Rapp, Birgit;
Marie, Isabelle;
Levy, David E.;
Jamieson, Amanda M.;
Decker, Thomas

Publication type:

Article

Interferon-induced nuclear signalling by Jak protein tyrosine kinases.

Published in:

Nature, 1993, v. 366, n. 6455, p. 583, doi. 10.1038/366583a0

By:

Silvennoinen, Olli;
Ihle, James N.;
Schlessinger, Joseph;
Levy, David E.

Publication type:

Article

Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export.

Published in:

Journal of Cell Biology, 2012, v. 196, n. 3, p. 315, doi. 10.1083/jcb.201107058

By:

Liang Zhang;
Das, Priyabrata;
Schmolke, Mirco;
Manicassamy, Balaji;
Yaming Wang;
Xiaoyi Deng;
Ling Cai;
Tu, Benjamin P.;
Forst, Christian V.;
Roth, Michael G.;
Levy, David E.;
García-Sastre, Adolfo;
de Brabander, Jef;
Phillips, Margaret A.;
Fontoura, Beatriz M. A.

Publication type:

Article

Art and the Brain: The Influence of Art on Roger Shepard's Studies of Mental Rotation.

Published in:

Journal of the History of the Neurosciences, 2004, v. 13, n. 1, p. 79, doi. 10.1080/09647040490885510

By:

Levy, Ellen K.;
Levy, David E.;
Goldberg, Michael E.

Publication type:

Article

Knockdown of Stat3 activity in vivo prevents diabetic glomerulopathy.

Published in:

Kidney International, 2009, v. 76, n. 1, p. 63, doi. 10.1038/ki.2009.98

By:

Ting-Chi Lu;
Zhao-Hui Wang;
Xiaobei Feng;
Chuang, Peter Y.;
Wei Fang;
Yuhong Shen;
Levy, David E.;
Huabao Xiong;
Nan Chen;
He, John Cijiang

Publication type:

Article

Signal transducer and activator of transcription 4 limits the development of adaptive regulatory T cells.

Published in:

Immunology, 2009, v. 127, n. 4, p. 587, doi. 10.1111/j.1365-2567.2008.03037.x

By:

O'Malley, John T.;
Sehra, Sarita;
Thieu, Vivian T.;
Qing Yu;
Hua-Chen Chang;
Stritesky, Gretta L.;
Nguyen, Evelyn T.;
Mathur, Anubhav N.;
Levy, David E.;
Kaplan, Mark H.

Publication type:

Article

Aligning, Integrating, and Synthesizing Leadership Development Education at the U.S. Air Force Academy: A Small Success Story.

Published in:

Journal of Character & Leadership Development (JCLD), 2023, v. 10, n. 2, p. 42, doi. 10.58315/jcld.v10.270

By:

Orlowsky, Matthew M.;
Day, Courtney E.;
Kelley, Christopher P.;
Levy, David E.;
Metcalfe, Amanda;
Rosenberg, Trevor

Publication type:

Article

Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death.

Published in:

Oncogene, 2002, v. 21, n. 7, p. 1038, doi. 10.1038/sj.onc.1205152

By:

Zamo, Alberto;
Chiarle, Roberto;
Piva, Roberto;
Howes, Jennifer;
Yan Fan;
Chilosi, Marco;
Levy, David E.;
Inghirami, Giorgio

Publication type:

Article

Divergent roles of STAT1 and STAT5 in malignancy as revealed by gene disruptions in mice.

Published in:

Oncogene, 2000, v. 19, n. 21, p. 2505, doi. 10.1038/sj.onc.1203480

By:

Levy, David E;
Gilliland, D Gary

Publication type:

Article

STAT1-deficient mice spontaneously develop estrogen receptor α-positive luminal mammary carcinomas.

Published in:

2012

By:

Chan, Szeman Ruby;
Vermi, William;
Luo, Jingqin;
Lucini, Laura;
Rickert, Charles;
Fowler, Amy M;
Lonardi, Silvia;
Arthur, Cora;
Young, Larry Jt;
Levy, David E;
Welch, Michael J;
Cardiff, Robert D;
Schreiber, Robert D

Publication type:

journal article

Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target.

Published in:

Nature Medicine, 2005, v. 11, n. 6, p. 623, doi. 10.1038/nm1249

By:

Chiarle, Roberto;
Simmons, William J;
Cai, Honjying;
Dhall, Girish;
Zamo, Alberto;
Raz, Regina;
Karras, James G;
Levy, David E;
Inghirami, Giorgio

Publication type:

Article

C. elegans STAT: evolution of a regulatory switch.

Published in:

FASEB Journal, 2006, v. 20, n. 10, p. 1641, doi. 10.1096/fj.06-6051com

By:

Yaming Wang;
Levy, David E.

Publication type:

Article

Disruption of the gamma-interferon signaling pathway at the level of signal transducer and activator of transcription-1 prevents immune destruction of beta-cells.

Published in:

2005

By:

Gysemans CA;
Ladrière L;
Callewaert H;
Rasschaert J;
Flamez D;
Levy DE;
Matthys P;
Eizirik DL;
Mathieu C;
Gysemans, Conny A;
Ladrière, Laurence;
Callewaert, Hanne;
Rasschaert, Joanne;
Flamez, Daisy;
Levy, David E;
Matthys, Patrick;
Eizirik, Décio L;
Mathieu, Chantal

Publication type:

journal article

Disruption of the γ-Interferon Signaling Pathway at the Level of Signal Transducer and Activator of Transcription-1 Prevents Immune Destruction of β-cells.

Published in:

Diabetes, 2005, v. 54, n. 8, p. 2396, doi. 10.2337/diabetes.54.8.2396

By:

Gysemans, Conny A.;
Ladrière, Laurence;
Callewaert, Hanne;
Rasschaert, Joanne;
Flamez, Daisy;
Levy, David E.;
Matthys, Patrick;
Eizirik, Décio L.;
Mathieu, Chantal

Publication type:

Article

Proto-oncogene PML controls genes devoted to MHC class I antigen presentation.

Published in:

Nature, 1998, v. 396, n. 6709, p. 373, doi. 10.1038/24628

By:

Pan Zheng;
Yong Guo;
Qingtian Niu;
Levy, David E.;
Dyck, Jacqueline A.;
Shengli Lu;
Sheiman, Lori A.;
Yang Liu

Publication type:

Article

IFN-Stimulated transcription through a TBP-free acetyltransferase complex escapes viral shutoff.

Published in:

Nature Cell Biology, 2002, v. 4, n. 2, p. 140, doi. 10.1038/ncb747

By:

Paulson, Matthew;
Press, Carolyn;
Smith, Eric;
Tanese, Naoko;
Levy, David E.

Publication type:

Article

The MEK-ERK Pathway Is Necessary for Serine Phosphorylation of Mitochondrial STAT3 and Ras-Mediated Transformation.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0083395

By:

Gough, Daniel J.;
Koetz, Lisa;
Levy, David E.

Publication type:

Article

A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells.

Published in:

2011

By:

Manel, Nicolas;
Hogstad, Brandon;
Wang, Yaming;
Levy, David E.;
Unutmaz, Derya;
Littman, Dan R.

Publication type:

Correction Notice

A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells.

Published in:

Nature, 2010, v. 467, n. 7312, p. 214, doi. 10.1038/nature09337

By:

Manel, Nicolas;
Hogstad, Brandon;
Wang, Yaming;
Levy, David E.;
Unutmaz, Derya;
Littman, Dan R.

Publication type:

Article

Stat1 and Stat2 but Not Stat3 Arbitrate Contradictory Growth Signals Elicited by Alpha/Beta Interferon in T Lymphocytes.

Published in:

Molecular & Cellular Biology, 2005, v. 25, n. 13, p. 5456, doi. 10.1128/MCB.25.13.5456-5465.2005

By:

Gimeno, Ramon;
Chien-Kuo Lee;
Schindler, Christian;
Levy, David E.

Publication type:

Article

Essential Role of STAT3 in Postnatal Survival and Growth Revealed by Mice Lacking STAT3 Serine 727 Phosphorylation.

Published in:

Molecular & Cellular Biology, 2004, v. 24, n. 1, p. 407, doi. 10.1128/MCB.24.1.407-419.2004

By:

Yuhong Shen;
Schlessinger, Karni;
Xuejun Zhu, Karni;
Meffre, Eric;
Quimby, Fred;
Levy, David E.;
Darnell Jr., J.E.

Publication type:

Article

Prognosis in nontraumatic coma.

Published in:

1981

By:

Levy, David E.;
Bates, David;
Caronna, John J.;
Cartridge, Niall E.T;
Robin, M.B.;
Jones, P. Knill;
Lapinski, Robert H.;
Singer, Borton H.;
Shaw, David A.;
Plum, Fred;
Levy, D E;
Bates, D;
Caronna, J J;
Cartlidge, N E;
Knill-Jones, R P;
Lapinski, R H;
Singer, B H;
Shaw, D A;
Plum, F

Publication type:

journal article

Regional cerebral blood flow and glucose metabolism following transient forebrain ischemia.

Published in:

Annals of Neurology, 1982, v. 11, n. 5, p. 499, doi. 10.1002/ana.410110510

By:

Pulsinelli, William A.;
Levy, David E.;
Duffy, Thomas E.

Publication type:

Article

Delayed pentobarbital administration limits ischemic brain damage in gerbils.

Published in:

Annals of Neurology, 1979, v. 5, n. 1, p. 59, doi. 10.1002/ana.410050109

By:

Levy, David E.;
Brierley, James B.

Publication type:

Article

Ancrod: A Potential Treatment for Acute, Ischemic Stroke from Snake Venom.

Published in:

Toxin Reviews, 2006, v. 25, n. 4, p. 323, doi. 10.1080/15569540600567354

By:

Levy, David E.;
Del Zoppo, Gregory

Publication type:

Article

ANCROD: A POTENTIAL TREATMENT FOR ACUTE, ISCHEMIC STROKE FROM SNAKE VENOM.

Published in:

Toxin Reviews, 2006, v. 25, n. 3, p. 319, doi. 10.1080/15569540600567354

By:

Levy, David E.;
Del Zoppo, Gregory J.

Publication type:

Article

PKR Transduces MDA5-Dependent Signals for Type I IFN Induction.

Published in:

PLoS Pathogens, 2016, v. 12, n. 3, p. 1, doi. 10.1371/journal.ppat.1005489

By:

Pham, Alissa M.;
Santa Maria, Felicia Gilfoy;
Lahiri, Tanaya;
Friedman, Eugene;
Marié, Isabelle J.;
Levy, David E.

Publication type:

Article