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Therapeutic and immunological interventions in primary biliary cholangitis: from mouse models to humans.
Published in:
2018
By:
- Atsushi Tanaka;
- Leung, Patrick S. C.;
- Young, Howard A.;
- Gershwin, M. Eric;
- Tanaka, Atsushi
Publication type:
journal article
Reestablish immune tolerance in rheumatoid arthritis.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1012868
By:
- Ziqiang Shuai;
- Shuang Zheng;
- Kang Wang;
- Jian Wang;
- Leung, Patrick S. C.;
- Bin Xu
Publication type:
Article
Decreased CD57 expression of natural killer cells enhanced cytotoxicity in patients with primary sclerosing cholangitis.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.912961
By:
- Bin Liu;
- Guo-Xiang Yang;
- Ying Sun;
- Takashi Tomiyama;
- Weici Zhang;
- Leung, Patrick S. C.;
- Xiao-Song He;
- Dhaliwal, Sandeep;
- Invernizzi, Pietro;
- Gershwin, M. Eric;
- Bowlus, Christopher L.
Publication type:
Article
Effect of LncRNA XIST on Immune Cells of Primary Biliary Cholangitis.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.816433
By:
- She, Chunhui;
- Yang, Yifei;
- Zang, Bo;
- Yao, Yuan;
- Liu, Qixuan;
- Leung, Patrick S. C.;
- Liu, Bin
Publication type:
Article
Anti-drug Antibodies Against a Novel Humanized Anti-CD20 Antibody Impair Its Therapeutic Effect on Primary Biliary Cholangitis in Human CD20- and FcγR-Expressing Mice.
Published in:
Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.02534
By:
- Moritoki, Yuki;
- Tsuneyama, Koichi;
- Nakamura, Yuka;
- Kikuchi, Kentaro;
- Shiota, Akira;
- Ohsugi, Yoshiyuki;
- Lian, Zhe-Xiong;
- Zhang, Weici;
- Yang, Guo-Xiang;
- Ueki, Shigeharu;
- Takeda, Masahide;
- Omokawa, Ayumi;
- Saga, Tomoo;
- Saga, Akiko;
- Watanabe, Daisuke;
- Miura, Masahito;
- Ueno, Yoshiyuki;
- Leung, Patrick S. C.;
- Tanaka, Atsushi;
- Gershwin, M. Eric
Publication type:
Article
The Critical Role of Chemokine (C–C Motif) Receptor 2-Positive Monocytes in Autoimmune Cholangitis.
Published in:
Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.01852
By:
- Reuveni, Debby;
- Gore, Yael;
- Leung, Patrick S. C.;
- Lichter, Yael;
- Moshkovits, Itay;
- Kaminitz, Ayelet;
- Brazowski, Eli;
- Lefebvre, Eric;
- Vig, Pamela;
- Varol, Chen;
- Halpern, Zamir;
- Shibolet, Oren;
- Gershwin, Merrill Eric;
- Zigmond, Ehud
Publication type:
Article
Innate Immunity Drives the Initiation of a Murine Model of Primary Biliary Cirrhosis.
Published in:
PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0121320
By:
- Chang, Chao-Hsuan;
- Chen, Ying-Chun;
- Zhang, Weici;
- Leung, Patrick S. C.;
- Gershwin, M. Eric;
- Chuang, Ya-Hui
Publication type:
Article
Immunization with Hypoallergens of Shrimp Allergen Tropomyosin Inhibits Shrimp Tropomyosin Specific IgE Reactivity.
Published in:
PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0111649
By:
- Wai, Christine Y. Y.;
- Leung, Nicki Y. H.;
- Ho, Marco H. K.;
- Gershwin, Laurel J.;
- Shu, Shang An;
- Leung, Patrick S. C.;
- Chu, Ka Hou
Publication type:
Article
Lymphoma-Like T Cell Infiltration in Liver Is Associated with Increased Copy Number of Dominant Negative Form of TGFβ Receptor II.
Published in:
PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0049413
By:
- Weici Zhang;
- Tsuda, Masanobu;
- Guo-Xiang Yang;
- Tsuneyama, Koichi;
- Xiao-Song He;
- Ansari, Aftab A.;
- Ridgway, William M.;
- Coppel, Ross L.;
- Zhe-Xiong Lian;
- Leung, Patrick S. C.;
- Gershwin, M. Eric
Publication type:
Article
Transgenic Overexpression of Aryl Hydrocarbon Receptor Repressor (AhRR) and AhR-Mediated Induction of CYP1A1, Cytokines, and Acute Toxicity.
Published in:
Environmental Health Perspectives, 2016, v. 124, n. 7, p. 1071, doi. 10.1289/ehp.1510194
By:
- Vogel, Christoph F. A.;
- Chang, W. L. William;
- Kado, Sarah;
- McCulloh, Kelly;
- Vogel, Helena;
- Wu, Dalei;
- Haarmann-Stemmann, Thomas;
- GuoXiang Yang;
- Leung, Patrick S. C.;
- Matsumura, Fumio;
- Gershwin, M. Eric
Publication type:
Article
Dietary therapy of murine primary biliary cholangitis induces hepatocellular steatosis: A cautionary tale.
Published in:
Liver International, 2024, v. 44, n. 10, p. 2834, doi. 10.1111/liv.16060
By:
- Zhang, Weici;
- Al Tekreeti, Taha;
- Leung, Patrick S. C.;
- Tsuneyama, Koichi;
- Dhillon, Harleen;
- Rojas, Manuel;
- Heuer, Luke S.;
- Ridgway, William M.;
- Ansari, Aftab A.;
- Young, Howard A.;
- Mackay, Charles R.;
- Gershwin, M. Eric
Publication type:
Article
Conventional type 1 dendritic cells are essential for the development of primary biliary cholangitis.
Published in:
Liver International, 2024, v. 44, n. 8, p. 2063, doi. 10.1111/liv.15961
By:
- Reuveni, Debby;
- Assi, Siwar;
- Gore, Yael;
- Brazowski, Eli;
- Leung, Patrick S. C.;
- Shalit, Tali;
- Gershwin, Merrill E.;
- Zigmond, Ehud
Publication type:
Article
Differential immune response to xenobiotic‐modified self‐molecule in simple and connective tissue disease‐associated primary biliary cholangitis.
Published in:
Liver International, 2022, v. 42, n. 10, p. 2204, doi. 10.1111/liv.15360
By:
- Ge, Shangqing;
- Xu, Qinyao;
- Li, Haiyan;
- Shao, Tihong;
- Zhong, Feng;
- Leung, Patrick S. C.;
- Shuai, Zongwen
Publication type:
Article
Mechanism-based target therapy in primary biliary cholangitis: opportunities before liver cirrhosis?
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1184252
By:
- Yushu Yang;
- XiaoSong He;
- Rojas, Manuel;
- Leung, Patrick S. C.;
- Lixia Gao
Publication type:
Article
Targeting immune checkpoints in anti-neutrophil cytoplasmic antibodies associated vasculitis: the potential therapeutic targets in the future.
Published in:
Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1156212
By:
- Menglu Pan;
- Huanhuan Zhao;
- Ruimin Jin;
- Leung, Patrick S. C.;
- Zongwen Shuai
Publication type:
Article
Interleukin 23 Produced by Hepatic Monocyte-Derived Macrophages Is Essential for the Development of Murine Primary Biliary Cholangitis.
Published in:
Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.718841
By:
- Reuveni, Debby;
- Brezis, Miriam R.;
- Brazowski, Eli;
- Vinestock, Philip;
- Leung, Patrick S. C.;
- Thakker, Paresh;
- Gershwin, M. Eric;
- Zigmond, Ehud
Publication type:
Article
Environmental basis of primary biliary cholangitis.
Published in:
Experimental Biology & Medicine, 2018, v. 243, n. 2, p. 184, doi. 10.1177/1535370217748893
By:
- Tanaka, Atsushi;
- Leung, Patrick S. C.;
- Gershwin, M. Eric
Publication type:
Article
Comprehending the allergen repertoire of shrimp for precision molecular diagnosis of shrimp allergy.
Published in:
Allergy, 2022, v. 77, n. 10, p. 3041, doi. 10.1111/all.15370
By:
- Wai, Christine Y. Y.;
- Leung, Nicki Y. H.;
- Leung, Agnes S. Y.;
- Ngai, Sai Ming;
- Pacharn, Punchama;
- Yau, Yat Sun;
- Rosa Duque, Jaime Sou Da;
- Kwan, Mike Y. W.;
- Jirapongsananuruk, Orathai;
- Chan, Wai Hung;
- Chua, Gilbert T.;
- Lee, Qun Ui;
- Piboonpocanun, Surapon;
- Ho, Po Ki;
- Wong, Joshua S. C.;
- Li, Shanshan;
- Xu, Kary J. Y.;
- Wong, Gary W. K.;
- Chu, Ka Hou;
- Leung, Patrick S. C.
Publication type:
Article
The molecular basis of immune regulation in autoimmunity.
Published in:
Clinical Science, 2018, v. 132, n. 1, p. 43, doi. 10.1042/CS20171154
By:
- Shu-Han Yang;
- Cai-yue Gao;
- Liang Li;
- Chang, Christopher;
- Leung, Patrick S. C.;
- Gershwin, M. Eric;
- Zhe-Xiong Lian
Publication type:
Article
Shrimp Extract Exacerbates Allergic Immune Responses in Mice: Implications on Clinical Diagnosis of Shellfish Allergy.
Published in:
Clinical Reviews in Allergy & Immunology, 2024, v. 66, n. 2, p. 250, doi. 10.1007/s12016-024-08994-4
By:
- Tong, Wai Sze;
- Li, Shanshan;
- Leung, Nicki Y. H.;
- Wong, Wing Tak;
- Leung, Ting Fan;
- Leung, Patrick S. C.;
- Chu, Ka Hou;
- Wai, Christine Y. Y.
Publication type:
Article
The Evolving Landscape of Fecal Microbial Transplantation.
Published in:
Clinical Reviews in Allergy & Immunology, 2023, v. 65, n. 2, p. 101, doi. 10.1007/s12016-023-08958-0
By:
- Shao, Tihong;
- Hsu, Ronald;
- Hacein-Bey, Camelia;
- Zhang, Weici;
- Gao, Lixia;
- Kurth, Mark J.;
- Zhao, Huanhuan;
- Shuai, Zongwen;
- Leung, Patrick S. C.
Publication type:
Article
New Mechanistic Advances in FcεRI-Mast Cell–Mediated Allergic Signaling.
Published in:
Clinical Reviews in Allergy & Immunology, 2022, v. 63, n. 3, p. 431, doi. 10.1007/s12016-022-08955-9
By:
- Li, Yang;
- Leung, Patrick S. C.;
- Gershwin, M. Eric;
- Song, Junmin
Publication type:
Article
Principles of Allergen Immunotherapy and Its Clinical Application in China: Contrasts and Comparisons with the USA.
Published in:
Clinical Reviews in Allergy & Immunology, 2019, v. 57, n. 1, p. 128, doi. 10.1007/s12016-019-08751-y
By:
- Guan, Kai;
- Liu, Bin;
- Wang, Meng;
- Li, Zhi;
- Chang, Christopher;
- Cui, Le;
- Wang, Rui-Qi;
- Wen, Li-Ping;
- Leung, Patrick S. C.;
- Wei, Ji-Fu;
- Sun, Jin-Lyu
Publication type:
Article
Microbiota and Food Allergy.
Published in:
Clinical Reviews in Allergy & Immunology, 2019, v. 57, n. 1, p. 83, doi. 10.1007/s12016-018-8723-y
By:
- Shu, Shang-An;
- Yuen, Agatha W. T.;
- Woo, Elena;
- Chu, Ka-Hou;
- Kwan, Hoi-Shan;
- Yang, Guo-Xiang;
- Yang, Yao;
- Leung, Patrick S. C.
Publication type:
Article
Regional Differences in Food Allergies.
Published in:
Clinical Reviews in Allergy & Immunology, 2019, v. 57, n. 1, p. 98, doi. 10.1007/s12016-018-8725-9
By:
- Tang, Rui;
- Wang, Zi-Xi;
- Ji, Chun-Mei;
- Leung, Patrick S. C.;
- Woo, Elena;
- Chang, Christopher;
- Wang, Meng;
- Liu, Bin;
- Wei, Ji-Fu;
- Sun, Jin-Lyu
Publication type:
Article
Immunotherapy of Food Allergy: a Comprehensive Review.
Published in:
Clinical Reviews in Allergy & Immunology, 2019, v. 57, n. 1, p. 55, doi. 10.1007/s12016-017-8647-y
By:
- Wai, Christine Y. Y.;
- Leung, Nicki Y. H.;
- Leung, Patrick S. C.;
- Chu, Ka Hou
Publication type:
Article
Common Variable Immunodeficiency and Liver Involvement.
Published in:
Clinical Reviews in Allergy & Immunology, 2018, v. 55, n. 3, p. 340, doi. 10.1007/s12016-017-8638-z
By:
- Song, Junmin;
- Lleo, Ana;
- Yang, Guo Xiang;
- Zhang, Weici;
- Bowlus, Christopher L.;
- Gershwin, M. Eric;
- Leung, Patrick S. C.
Publication type:
Article
The Clinical Significance of GP73 in Immunologically Mediated Chronic Liver Diseases: Experimental Data and Literature Review.
Published in:
Clinical Reviews in Allergy & Immunology, 2018, v. 54, n. 2, p. 282, doi. 10.1007/s12016-017-8655-y
By:
- Yao, Mingjie;
- Wang, Leijie;
- Leung, Patrick S. C.;
- Li, Yanmei;
- Liu, Shuhong;
- Wang, Lu;
- Guo, Xiaodong;
- Zhou, Guangde;
- Yan, Ying;
- Guan, Guiwen;
- Chen, Xiangmei;
- Bowlus, Christopher L.;
- Liu, Tianhui;
- Jia, Jidong;
- Gershwin, M. Eric;
- Ma, Xiong;
- Zhao, Jingmin;
- Lu, Fengmin
Publication type:
Article

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