Works matching AU Leung, Geoffrey Ho Duen

Results: 8

AI-Driven Drug Target Screening Platform Identified Oncogene CACNA2D1 Activated by Enhancer Infestation in Epstein-Barr Virus-Associated Nasopharyngeal Carcinoma.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4697, doi. 10.3390/ijms26104697

By:

Chung, Dittman Lai-Shun;
Leung, Geoffrey Ho Duen;
Liu, Songran;
Lok, Sarah Wing Yan;
Xin, Ying;
Xia, Yunfei;
Zhavoronkov, Alex;
Pun, Frank W.;
Ng, Wai-Tong;
Dai, Wei

Publication type:

Article

Leveraging AI to identify dual-purpose aging and disease targets.

Published in:

2024

By:

Leung, Geoffrey Ho Duen;
Wong, Chun Wai;
Pun, Frank W.;
Aliper, Alex;
Ren, Feng;
Zhavoronkov, Alex

Publication type:

Editorial

A comprehensive AI‐driven analysis of large‐scale omic datasets reveals novel dual‐purpose targets for the treatment of cancer and aging.

Published in:

Aging Cell, 2023, v. 22, n. 12, p. 1, doi. 10.1111/acel.14017

By:

Pun, Frank W.;
Leung, Geoffrey Ho Duen;
Leung, Hoi Wing;
Rice, Jared;
Schmauck‐Medina, Tomas;
Lautrup, Sofie;
Long, Xi;
Liu, Bonnie Hei Man;
Wong, Chun Wai;
Ozerov, Ivan V.;
Aliper, Alex;
Ren, Feng;
Rosenberg, Ari J.;
Agrawal, Nishant;
Izumchenko, Evgeny;
Fang, Evandro F.;
Zhavoronkov, Alex

Publication type:

Article

Identification of IncRNAs associated with uterine corpus endometrial cancer prognosis based on the competing endogenous RNA network.

Published in:

International Journal of Medical Sciences, 2023, v. 20, n. 12, p. 1600, doi. 10.7150/ijms.87430

By:

Liangxiao Wang;
Xianwei Su;
Liangyu Wang;
Jianbo Luo;
Zhiqiang Xiong;
Ho Duen Leung, Geoffrey;
Jingye Zhou;
Guang Yang;
Li Zhai;
Xi Zhang;
Qiang Liu;
Gang Lu;
Yuming Wang

Publication type:

Article

Circulating microRNAs as diagnostic biomarkers for ischemic stroke: evidence from comprehensive analysis and real-world validation.

Published in:

International Journal of Medical Sciences, 2023, v. 20, n. 8, p. 1009, doi. 10.7150/ijms.83963

By:

Yang Wang;
Xianwei Su;
Ho Duen Leung, Geoffrey;
Baohua Ren;
Qiang Zhang;
Zhiqiang Xiong;
Jingye Zhou;
Ling Yang;
Gang Lu;
Wai-Yee Chan;
Lijie Ren

Publication type:

Article

Precious2GPT: the combination of multiomics pretrained transformer and conditional diffusion for artificial multi-omics multi-species multi-tissue sample generation.

Published in:

NPJ Aging, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41514-024-00163-3

By:

Sidorenko, Denis;
Pushkov, Stefan;
Sakip, Akhmed;
Leung, Geoffrey Ho Duen;
Lok, Sarah Wing Yan;
Urban, Anatoly;
Zagirova, Diana;
Veviorskiy, Alexander;
Tihonova, Nina;
Kalashnikov, Aleksandr;
Kozlova, Ekaterina;
Naumov, Vladimir;
Pun, Frank W.;
Aliper, Alex;
Ren, Feng;
Zhavoronkov, Alex

Publication type:

Article

Identification of Therapeutic Targets for Amyotrophic Lateral Sclerosis Using PandaOmics – An AI-Enabled Biological Target Discovery Platform.

Published in:

Frontiers in Aging Neuroscience, 2022, v. 14, p. 1, doi. 10.3389/fnagi.2022.914017

By:

Pun, Frank W.;
Liu, Bonnie Hei Man;
Long, Xi;
Leung, Hoi Wing;
Leung, Geoffrey Ho Duen;
Mewborne, Quinlan T.;
Gao, Junli;
Shneyderman, Anastasia;
Ozerov, Ivan V.;
Wang, Ju;
Ren, Feng;
Aliper, Alexander;
Bischof, Evelyne;
Izumchenko, Evgeny;
Guan, Xiaoming;
Zhang, Ke;
Lu, Bai;
Rothstein, Jeffrey D.;
Cudkowicz, Merit E.;
Zhavoronkov, Alex

Publication type:

Article

Genome-wide identification of replication fork stalling/pausing sites and the interplay between RNA Pol II transcription and DNA replication progression.

Published in:

Genome Biology, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s13059-024-03278-8

By:

Rojas, Patricia;
Wang, Jianming;
Guglielmi, Giovanni;
Sadurnì, Martina Mustè;
Pavlou, Lucas;
Leung, Geoffrey Ho Duen;
Rajagopal, Vijay;
Spill, Fabian;
Saponaro, Marco

Publication type:

Article