Works by Leung, Fung Ping

Results: 38

Protopanaxadiol and protopanaxatriol bind to glucocorticoid and oestrogen receptors in endothelial cells.

Published in:

2009

By:

Kar Wah Leung;
Fung Ping Leung;
Nai Ki Mak;
Tombran-Tink, Joyce;
Yu Huang;
Wong, Ricky N. S.;
Leung, Kar Wah;
Leung, Fung Ping;
Mak, Nai Ki;
Huang, Yu

Publication type:

journal article

Phosphoinositide 3-kinase gamma in T cell biology and disease therapy.

Published in:

Annals of the New York Academy of Sciences, 2013, v. 1280, n. 1, p. 40, doi. 10.1111/nyas.12029

By:

Fung‐Leung, Wai‐Ping

Publication type:

Article

Cilnidipine, a slow-acting Ca2+ channel blocker, induces relaxation in porcine coronary artery: role of endothelial nitric oxide and [Ca2+]i.

Published in:

British Journal of Pharmacology, 2006, v. 147, n. 1, p. 55, doi. 10.1038/sj.bjp.0706450

By:

Hok Sum Leung;
Xiaoqiang Yao;
Fung Ping Leung;
Wing Hung Ko;
Zhen-Yu Chen;
Gollasch, Maik;
Yu Huang

Publication type:

Article

Histamine H4 receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation.

Published in:

British Journal of Pharmacology, 2004, v. 142, n. 1, p. 161, doi. 10.1038/sj.bjp.0705729

By:

Ping Ling;
Ngo, Karen;
Nguyen, Steven;
Thurmond, Robin L.;
Edwards, James P.;
Karlsson, Lars;
Wai-Ping Fung-Leung

Publication type:

Article

A Wrong Fate Decision in Adipose Stem Cells upon Obesity.

Published in:

Cells (2073-4409), 2023, v. 12, n. 4, p. 662, doi. 10.3390/cells12040662

By:

Cheung, Yiu-Ming;
Chook, Chui-Yiu-Bamboo;
Yeung, Hoi-Wa;
Leung, Fung-Ping;
Wong, Wing-Tak

Publication type:

Article

Immunological characterization of HM5023507, an orally active PI3Kδ/γ inhibitor.

Published in:

Pharmacology Research & Perspectives, 2020, v. 8, n. 1, p. 1, doi. 10.1002/prp2.559

By:

Yu Cai;
Jun Yu;
Ping Ren;
Jianlin He;
Zhipeng Wu;
Kun Xiao;
Hong Jia;
Jian Wang;
Yang Sai;
Guangxiu Dai;
Xiong Li;
Weiguo Su;
Karen Ngo;
Castro, Glenda;
Acton, Paul D.;
Wai-Ping Fung-Leung;
Edwards, James P.;
Venable, Jennifer;
Rao, Tadimeti S.

Publication type:

Article

PI3Kγ kinase activity is required for optimal T-cell activation and differentiation.

Published in:

European Journal of Immunology, 2013, v. 43, n. 12, p. 3183, doi. 10.1002/eji.201343812

By:

Ladygina, Nadia;
Gottipati, Sridevi;
Ngo, Karen;
Castro, Glenda;
Ma, Jing‐Ying;
Banie, Homayon;
Rao, Tadimeti S.;
Fung‐Leung, Wai‐Ping

Publication type:

Article

T Cell Subset and Stimulation Strength-Dependent Modulation of T Cell Activation by Kv1.3 Blockers.

Published in:

PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0170102

By:

Fung-Leung, Wai-Ping;
Edwards, Wilson;
Liu, Yi;
Ngo, Karen;
Angsana, Julianty;
Castro, Glenda;
Wu, Nancy;
Liu, Xuejun;
Swanson, Ronald V.;
Wickenden, Alan D.

Publication type:

Article

CpG-induced tyrosine phosphorylation occurs via a TLR-9 independent mechanism and is required for cytokine secretion.

Published in:

Journal of Cell Biology, 2006, v. 172, n. 7, p. 1057, doi. 10.1083/jcb.200508058

By:

Sanjuan, Miguel A.;
Rao, Navin;
Lai, Kuei-Tai A.;
Gu, Yin;
Sun, Siquan;
Fung-Leung, Wai-Ping;
Karlsson, Lars;
Fuchs, Anja;
Colonna, Marco

Publication type:

Article

IL‐4/STAT6 axis observed to reverse proliferative defect in SCA3 patient‐derived neural progenitor cells.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2024, v. 51, n. 1, p. 30, doi. 10.1111/1440-1681.13831

By:

Chen, Francis M.;
Li, Huixian;
Chung, Dittman Lai‐Shun;
Mak, Angel T. L.;
Leung, Fung Ping;
Chan, Ho Yin Edwin;
Wong, Wing Tak

Publication type:

Article

Potential of crocodile blood as a medication and dietary supplement: A systemic review.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2021, v. 48, n. 8, p. 1043, doi. 10.1111/1440-1681.13524

By:

Chook, Chui Yiu Bamboo;
Chen, Francis M.;
Leung, Fung Ping;
Chen, Zhen‐Yu;
Wong, Wing Tak

Publication type:

Article

RALOXIFENE, TAMOXIFEN AND VASCULAR TONE.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2007, v. 34, n. 8, p. 809, doi. 10.1111/j.1440-1681.2007.04684.x

By:

Leung, Fung Ping;
Tsang, Suk Ying;
Wong, Chi Ming;
Yung, Lai Ming;
Chan, Yau Chi;
Leung, Hok Sum;
Yao, Xiaoqiang;
Huang, Yu

Publication type:

Article

RORγt and RORα signature genes in human Th17 cells.

Published in:

PLoS ONE, 2017, v. 12, n. 8, p. 1, doi. 10.1371/journal.pone.0181868

By:

Castro, Glenda;
Liu, Xuejun;
Ngo, Karen;
De Leon-Tabaldo, Aimee;
Zhao, Shanrong;
Luna-Roman, Rosa;
Yu, Jingxue;
Cao, Tinghua;
Kuhn, Robert;
Wilkinson, Patrick;
Herman, Krystal;
Nelen, Marina I.;
Blevitt, Jonathan;
Xue, Xiaohua;
Fourie, Anne;
Fung-Leung, Wai-Ping

Publication type:

Article

The role of H2-O and HLA-DO in major histocompatibility complex class II-restricted antigen processing and presentation.

Published in:

Immunological Reviews, 1999, v. 172, n. 1, p. 255, doi. 10.1111/j.1600-065X.1999.tb01370.x

By:

Alfonso, Christopher;
Lilijedahl, Monika;
Winqvist, Ola;
Surh, Charles D.;
Peterson, Per A.;
Wai-Ping Fung-Leung;
Karlsson, Lars

Publication type:

Article

Comparison of New-Onset Peripheral Artery Disease in Patients With Type 2 Diabetes Exposed to Sodium-Glucose Cotransporter-2 Inhibitors, Dipeptidyl Peptidase-4 Inhibitors, or Glucagon-Like Peptide-1 Agonists: A Population-Based Cohort Study.

Published in:

Journal of the American Heart Association, 2025, v. 14, n. 11, p. 1, doi. 10.1161/JAHA.123.034175

By:

Hou-In Chou, Oscar;
Zhiyao Luo;
Cheuk To Skylar Chung;
Chan, Jeffrey;
Huixian Li;
Lakhani, Ishan;
Lee, Sharen;
Dawnie Ho Hei Lau;
Qingpeng Zhang;
Tong Liu;
Wing Tak Wong;
Man Yung Cheung, Bernard;
Lip, Gregory Y. H.;
Fung Ping Leung;
Tse, Gary;
Jiandong Zhou

Publication type:

Article

Exercise, Vascular Wall and Cardiovascular Diseases.

Published in:

Sports Medicine, 2009, v. 39, n. 1, p. 45, doi. 10.2165/00007256-200939010-00004

By:

Lai Ming Yung;
Laher, Ismail;
Xiaoqiang Yao;
Zhen Yu Chen;
Yu Huang;
Fung Ping Leung

Publication type:

Article

Exercise, Vascular Wall and Cardiovascular Diseases.

Published in:

Sports Medicine, 2008, v. 38, n. 12, p. 1006, doi. 10.2165/00007256-200838120-00005

By:

Fung Ping Leung;
Lai Ming Yung;
Laher, Ismail;
Xiaoqiang Yao;
Zhen Yu Chen;
Yu Huang

Publication type:

Article

Non-genomic effects of ginsenoside-Re in endothelial cells via glucocorticoid receptor

Published in:

FEBS Letters, 2007, v. 581, n. 13, p. 2423, doi. 10.1016/j.febslet.2007.04.055

By:

Leung, Kar Wah;
Leung, Fung Ping;
Huang, Yu;
Mak, Nai Ki;
Wong, Ricky N.S.

Publication type:

Article

Use of a Human Skin-Grafted Nude Mouse Model for the Evaluation of Topical Retinoic Acid Treatment.

Published in:

Journal of Investigative Dermatology, 1994, v. 102, n. 4, p. 515, doi. 10.1111/1523-1747.ep12373180

By:

Otulakowski, Gail;
Zhou, Lubing;
Fung-Leung, Wai-Ping;
Gendimenico, Gerard J.;
Samuel, Steven E. S.;
Lau, Catherine Y.

Publication type:

Article

Association between immune checkpoint inhibitors and myocardial infarction in Asians: A population‐based self‐controlled case series.

Published in:

Cancer Medicine, 2023, v. 12, n. 8, p. 9541, doi. 10.1002/cam4.5729

By:

Chan, Jeffrey Shi Kai;
Tang, Pias;
Lee, Teddy Tai Loy;
Chou, Oscar Hou In;
Lee, Yan Hiu Athena;
Li, Guoliang;
Leung, Fung Ping;
Wong, Wing Tak;
Liu, Tong;
Tse, Gary

Publication type:

Article

Type 2 innate immunity drives distinct neonatal immune profile conducive for heart regeneration.

Published in:

Theranostics, 2022, v. 12, n. 3, p. 1161, doi. 10.7150/thno.67515

By:

Chen, Francis M.;
Tse, Joyce K. Y.;
Leigang Jin;
Chui Yiu Bamboo Chook;
Fung Ping Leung;
Tse, Gary;
Woo, Connie W.;
Aimin Xu;
Chawla, Ajay;
Xiao Yu Tian;
Ting-Fung Chan;
Wing Tak Wong

Publication type:

Article

Licorice Extract Isoliquiritigenin Protects Endothelial Function in Type 2 Diabetic Mice.

Published in:

Nutrients, 2024, v. 16, n. 18, p. 3160, doi. 10.3390/nu16183160

By:

Wang, Lin;
Zhu, Ruiwen;
He, Chufeng;
Li, Huixian;
Zhang, Qile;
Cheung, Yiu Ming;
Leung, Fung Ping;
Wong, Wing Tak

Publication type:

Article

TRPV2 calcium channel promotes breast cancer progression potential by activating autophagy.

Published in:

Cancer Cell International, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12935-024-03506-y

By:

Li, Qing;
Li, Huixian;
Zhu, Ruiwen;
Cho, William Chi Shing;
Yao, Xiaoqiang;
Leung, Fung Ping;
Tse, Gary;
Leung, Lai Kwok;
Wong, Wing Tak

Publication type:

Article

Antagonism of the histamine H receptor reduces LPS-induced TNF production in vivo.

Published in:

Inflammation Research, 2013, v. 62, n. 6, p. 599, doi. 10.1007/s00011-013-0612-5

By:

Cowden, Jeffery;
Yu, Fuqu;
Challapalli, Mamatha;
Huang, Jing-Feng;
Kim, Sunhwa;
Fung-Leung, Wai-Ping;
Ma, Jing;
Riley, Jason;
Zhang, Mai;
Dunford, Paul;
Thurmond, Robin

Publication type:

Article

Comparison of RNA-Seq and Microarray in Transcriptome Profiling of Activated T Cells.

Published in:

PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0078644

By:

Zhao, Shanrong;
Fung-Leung, Wai-Ping;
Bittner, Anton;
Ngo, Karen;
Liu, Xuejun

Publication type:

Article

Inhibition of Renin-Angiotensin System Reverses Endothelial Dysfunction and Oxidative Stress in Estrogen Deficient Rats.

Published in:

PLoS ONE, 2011, v. 6, n. 3, p. 1, doi. 10.1371/journal.pone.0017437

By:

Lai Ming Yung;
Wing Tak Wong;
Xiao Yu Tian;
Fung Ping Leung;
Lai Hang Yung;
Zhen Yu Chen;
Xiaoqiang Yao;
Chi Wai Lau;
Yu Huang

Publication type:

Article

Tbt-1, a new T-box transcription factor induced in activated Th1 and CD8+ T cells.

Published in:

2000

By:

Shier, Peter;
Hofstra, Claudia L.;
Ma, Xiao-Jun;
Wu, Ying;
Ngo, Karen;
Fung-Leung, Wai-Ping

Publication type:

Erratum

Tbt-1, a new T-box transcription factor induced in activated Th1 and CD8+ T cells.

Published in:

Immunogenetics, 2000, v. 51, n. 10, p. 771, doi. 10.1007/s002510000212

By:

Shier, Peter;
Hofstra, Claudia L.;
Xiao-Jun Ma;
Ying Wu;
Ngo, Karen;
Wai-Ping Fung-Leung

Publication type:

Article

A Novel Splice Variant of Interleukin-1 Receptor (IL-1R)-Associated Kinase 1 Plays a Negative Regulatory Role in Toll/IL-1R-Induced Inflammatory Signaling.

Published in:

Molecular & Cellular Biology, 2005, v. 25, n. 15, p. 6521, doi. 10.1128/MCB.25.15.6521-6532.2005

By:

Rao, Navin;
Nguyen, Steven;
Ngo, Karen;
Wai-Ping Fung-Leung

Publication type:

Article

Estrogen Controls embryonic stem cell proliferation via store-operated calcium entry and the nuclear factor of activated T-cells (NFAT).

Published in:

Journal of Cellular Physiology, 2012, v. 227, n. 6, p. 2519, doi. 10.1002/jcp.22990

By:

Wong, Chun-Kit;
So, Wing-Yan;
Law, Sau-Kwan;
Leung, Fung-Ping;
Yau, Ka-Long;
Yao, Xiaoqiang;
Huang, Yu;
Li, Xiangdong;
Tsang, Suk-Ying

Publication type:

Article

Pharmacologic modulation of RORγt translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis.

Published in:

Scientific Reports, 2016, p. 37977, doi. 10.1038/srep37977

By:

Xue, Xiaohua;
Soroosh, Pejman;
De Leon-Tabaldo, Aimee;
Luna-Roman, Rosa;
Sablad, Marciano;
Rozenkrants, Natasha;
Yu, Jingxue;
Castro, Glenda;
Banie, Homayon;
Fung-Leung, Wai-Ping;
Santamaria-Babi, Luis;
Schlueter, Thomas;
Albers, Michael;
Leonard, Kristi;
Budelsky, Alison L.;
Fourie, Anne M.

Publication type:

Article

Black tea protects against hypertension-associated endothelial dysfunction through alleviation of endoplasmic reticulum stress.

Published in:

Scientific Reports, 2015, p. 10340, doi. 10.1038/srep10340

By:

San Cheang, Wai;
Yuen Ngai, Ching;
Yen Tam, Ye;
Yu Tian, Xiao;
Tak Wong, Wing;
Zhang, Yang;
Wai Lau, Chi;
Chen, Zhen Yu;
Bian, Zhao-Xiang;
Huang, Yu;
Ping Leung, Fung

Publication type:

Article

CD4-negative cytotoxic T cells with a T cell receptor α/β.

Published in:

European Journal of Immunology, 1996, v. 26, n. 1, p. 213, doi. 10.1002/eji.1830260133

By:

Dalloul, Ali H.;
Ngo, Karen;
Fung-Leung, Wai-Ping

Publication type:

Article

Tepoxalin blocks neutrophil migration into cutaneous inflammatory sites by inhibiting Mac-1 and E-selectin expression.

Published in:

European Journal of Immunology, 1996, v. 26, n. 1, p. 120, doi. 10.1002/eji.1830260119

By:

Zhou, Lubing;
Pope, Barbara L.;
Chourmouzis, Erika;
Fung-Leung, Wai-Ping;
Lau, Catherine Y.

Publication type:

Article

Murine lupus in MRL/ lpr mice lacking CD4 or CD8 T cells.

Published in:

European Journal of Immunology, 1995, v. 25, n. 9, p. 2558, doi. 10.1002/eji.1830250923

By:

Koh, Dow-Rhoon;
Ho, Alexandra;
Rahemtulla, Amin;
Fung-Leung, Wai-Ping;
Griesser, Henrik;
Mak, Tak-Wah

Publication type:

Article

The lack of CD8α cytoplasmic domain resulted in a dramatic decrease in efficiency in thymic maturation but only a moderate reduction in cytotoxic function of CD8.

Published in:

European Journal of Immunology, 1993, v. 23, n. 11, p. 2834, doi. 10.1002/eji.1830231117

By:

Fung-Leung, Wai-Ping;
Louie, Marjorie C.;
Limmer, Andreas;
Ohashi, Pamela S.;
Ngo, Karen;
Chen, Lei;
Kawai, Kazuhiro;
Lacy, Elizabeth;
Loh, Dennis Y.;
Mak, Tak W.

Publication type:

Article

Alloreactive cytotoxic T cells can develop and function in mice lacking both CD4 and CD8.

Published in:

European Journal of Immunology, 1993, v. 23, n. 6, p. 1299, doi. 10.1002/eji.1830230617

By:

Schilham, Marco W.;
Fung-Leung, Wai-Ping;
Rahemtulla, Amin;
Kuendig, Thomas;
Zhang, Li;
Potter, Julia;
Miller, Richard G.;
Hengartner, Hans;
Mak, Tak W.

Publication type:

Article

CD8 is needed for positive selection but differentially required for negative selection of T cells during thymic ontogeny.

Published in:

European Journal of Immunology, 1993, v. 23, n. 1, p. 212, doi. 10.1002/eji.1830230133

By:

Fung-Leung, Wai-Ping;
Wallace, Valerie A.;
Gray, Dawn;
Sha, William C.;
Pircher, Hanspeter;
Teh, Hung-Sia;
Loh, Dennis Y.;
Mak, Tak W.

Publication type:

Article

Works by Leung, Fung Ping

Protopanaxadiol and protopanaxatriol bind to glucocorticoid and oestrogen receptors in endothelial cells.

Phosphoinositide 3-kinase gamma in T cell biology and disease therapy.

Cilnidipine, a slow-acting Ca<sup>2+</sup> channel blocker, induces relaxation in porcine coronary artery: role of endothelial nitric oxide and [Ca<sup>2+</sup>]<sub>i</sub>.

Histamine H<sub>4</sub> receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation.

A Wrong Fate Decision in Adipose Stem Cells upon Obesity.

Immunological characterization of HM5023507, an orally active PI3Kδ/γ inhibitor.

PI3Kγ kinase activity is required for optimal T-cell activation and differentiation.

T Cell Subset and Stimulation Strength-Dependent Modulation of T Cell Activation by Kv1.3 Blockers.

CpG-induced tyrosine phosphorylation occurs via a TLR-9 independent mechanism and is required for cytokine secretion.

IL‐4/STAT6 axis observed to reverse proliferative defect in SCA3 patient‐derived neural progenitor cells.

Potential of crocodile blood as a medication and dietary supplement: A systemic review.

RALOXIFENE, TAMOXIFEN AND VASCULAR TONE.

RORγt and RORα signature genes in human Th17 cells.

The role of H2-O and HLA-DO in major histocompatibility complex class II-restricted antigen processing and presentation.

Comparison of New-Onset Peripheral Artery Disease in Patients With Type 2 Diabetes Exposed to Sodium-Glucose Cotransporter-2 Inhibitors, Dipeptidyl Peptidase-4 Inhibitors, or Glucagon-Like Peptide-1 Agonists: A Population-Based Cohort Study.

Exercise, Vascular Wall and Cardiovascular Diseases.

Exercise, Vascular Wall and Cardiovascular Diseases.

Non-genomic effects of ginsenoside-Re in endothelial cells via glucocorticoid receptor

Use of a Human Skin-Grafted Nude Mouse Model for the Evaluation of Topical Retinoic Acid Treatment.

Association between immune checkpoint inhibitors and myocardial infarction in Asians: A population‐based self‐controlled case series.

Type 2 innate immunity drives distinct neonatal immune profile conducive for heart regeneration.

Licorice Extract Isoliquiritigenin Protects Endothelial Function in Type 2 Diabetic Mice.

TRPV2 calcium channel promotes breast cancer progression potential by activating autophagy.

Antagonism of the histamine H receptor reduces LPS-induced TNF production in vivo.

Comparison of RNA-Seq and Microarray in Transcriptome Profiling of Activated T Cells.

Inhibition of Renin-Angiotensin System Reverses Endothelial Dysfunction and Oxidative Stress in Estrogen Deficient Rats.

Tbt-1, a new T-box transcription factor induced in activated Th1 and CD8<sup>+</sup> T cells.

Tbt-1, a new T-box transcription factor induced in activated Th1 and CD8<sup>+</sup> T cells.

A Novel Splice Variant of Interleukin-1 Receptor (IL-1R)-Associated Kinase 1 Plays a Negative Regulatory Role in Toll/IL-1R-Induced Inflammatory Signaling.

Estrogen Controls embryonic stem cell proliferation via store-operated calcium entry and the nuclear factor of activated T-cells (NFAT).

Pharmacologic modulation of RORγt translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis.

Black tea protects against hypertension-associated endothelial dysfunction through alleviation of endoplasmic reticulum stress.

CD4-negative cytotoxic T cells with a T cell receptor α/β.

Tepoxalin blocks neutrophil migration into cutaneous inflammatory sites by inhibiting Mac-1 and E-selectin expression.

Murine lupus in MRL/ lpr mice lacking CD4 or CD8 T cells.

The lack of CD8α cytoplasmic domain resulted in a dramatic decrease in efficiency in thymic maturation but only a moderate reduction in cytotoxic function of CD8.

Alloreactive cytotoxic T cells can develop and function in mice lacking both CD4 and CD8.

CD8 is needed for positive selection but differentially required for negative selection of T cells during thymic ontogeny.