Works by Leumann, Christian J.

Results: 63

Ein paralleles Testverfahren zur Entdeckung neuer DNA-Basenpaare.

Published in:

Angewandte Chemie, 2011, v. 123, n. 8, p. 1976, doi. 10.1002/ange.201005300

By:

Yaren, Oezlem;
Mosimann, Markus;
Leumann, Christian J.

Publication type:

Article

A Short, Efficient Synthesis of 2′-Deoxypseudoisocytidine Based on Heck-Chemistry.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 10, p. 1919, doi. 10.1081/NCN-120025239

By:

Mayer, Alain;
Leumann, Christian J.

Publication type:

Article

Pyrrolidino-DNA.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 5-8, p. 1187, doi. 10.1081/NCN-120022832

By:

Häberli, Adrian;
Mayer, Alain;
Leumann, Christian J.

Publication type:

Article

Fluorinated Peptide Nucleic Acid.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 5-8, p. 1191, doi. 10.1081/NCN-120022833

By:

Hollenstein, Marcel;
Gautschi, Daniel;
Leumann, Christian J.

Publication type:

Article

Transition Metal Ligands as Novel DNA-Base Substitutes.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 5-8, p. 1195, doi. 10.1081/NCN-120022834

By:

Brotschi, Christine;
Leumann, Christian J.

Publication type:

Article

New Nucleoside Analogues for the Recognition of Pyrimidine-Purine Inversion Sites.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 5-8, p. 1199, doi. 10.1081/NCN-120022835

By:

Buchini, Sabrina;
Leumann, Christian J.

Publication type:

Article

Synthetic Studies Towards a Novel, Chemical Stable, Abasic Site Analogue of DNA.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 5-8, p. 1203, doi. 10.1081/NCN-120022836

By:

Hirtz, Caroline;
Leumann, Christian J.

Publication type:

Article

Synthesis of a Cyclopentane Amide DNA Analogue and Its Base Pairing Properties.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 5-8, p. 1207, doi. 10.1081/NCN-120022837

By:

Ahn, Dae-Ro;
Mosimann, Markus;
Leumann, Christian J.

Publication type:

Article

Olefinic Peptide Nucleic Acid (OPA).

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 5-8, p. 1211, doi. 10.1081/NCN-120022838

By:

Gautschi, Daniel;
Leumann, Christian J.

Publication type:

Article

An assay for RNA oxidation induced abasic sites using the Aldehyde Reactive Probe.

Published in:

Free Radical Research, 2011, v. 45, n. 2, p. 237, doi. 10.3109/10715762.2010.535529

By:

Tanaka, Mikiei;
Song, Han;
Küpfer, Pascal A.;
Leumann, Christian J.;
Sonntag, William E.

Publication type:

Article

Trans-lesion synthesis and RNaseH activity by reverse transcriptases on a true abasic RNA template.

Published in:

Nucleic Acids Research, 2007, v. 35, n. 20, p. 6846, doi. 10.1093/nar/gkm767

By:

Küpfer, Pascal A.;
Crey-Desbiolles, Caroline;
Leumann, Christian J.

Publication type:

Article

The chemical stability of abasic RNA compared to abasic DNA.

Published in:

Nucleic Acids Research, 2007, v. 35, n. 1, p. 58, doi. 10.1093/nar/gkl948

By:

Küpfer, Pascal A.;
Leumann, Christian J.

Publication type:

Article

Molecular beacons with a homo-DNA stem: improving target selectivity.

Published in:

Nucleic Acids Research, 2005, v. 33, n. 8, p. e77, doi. 10.1093/nar/gni076

By:

Crey-Desbiolles, Caroline;
Ahn, Dae-Ro;
Leumann, Christian J.

Publication type:

Article

Nuclear antisense effects in cyclophilin A pre‐mRNA splicing by oligonucleotides: a comparison of tricyclo‐DNA with LNA.

Published in:

Nucleic Acids Research, 2004, v. 32, n. 1, p. 346, doi. 10.1093/nar/gkh187

By:

Ittig, Damian;
Liu, Songkai;
Renneberg, Dorte;
Schümperli, Daniel;
Leumann, Christian J.

Publication type:

Article

Antisense properties of tricyclo-DNA.

Published in:

Nucleic Acids Research, 2002, v. 30, n. 13, p. 2751, doi. 10.1093/nar/gkf412

By:

Renneberg, Dorte;
Bouliong, Emilie;
Reber, Ulrich;
Schümperli, Daniel;
Leumann, Christian J.

Publication type:

Article

Triple-helix formation in the antiparallel binding motif of oligodeoxynucleotides containing N9- and N7-2-aminopurine deoxynucleosides.

Published in:

Nucleic Acids Research, 2001, v. 29, n. 11, p. 2260, doi. 10.1093/nar/29.11.2260

By:

Parel, Serge P.;
Leumann, Christian J.

Publication type:

Article

Oligodeoxynucleotides containing conformationally constrained abasic sites: a UV and fluorescence spectroscopic investigation on duplex stability and structure.

Published in:

Nucleic Acids Research, 2000, v. 28, n. 14, p. 2702, doi. 10.1093/nar/28.14.2702

By:

Pompizi, Isabelle;
Häberli, Adrian;
Leumann, Christian J.

Publication type:

Article

Inhibition of DNA polymerase reactions by pyrimidine nucleotide analogues lacking the 2‐keto group.

Published in:

Nucleic Acids Research, 1998, v. 26, n. 8, p. 1863, doi. 10.1093/nar/26.8.1863

By:

Guo, Mao‐Jun;
Hildbrand, Stefan;
Leumann, Christian J.;
McLaughlin, Larry W.;
Waring, Michael J.

Publication type:

Article

Stable and Selective Recognition of Three Base Pairs in the Parallel Triple-Helical DNA Binding MotifThe authors thank Christine Brotschi, Alain Mayer, and Dorte Renneberg for advice on experimental procedures. Financial support from the Swiss National Science Foundation (Grant no. 200020-100178) is gratefully acknowledged.

Published in:

Angewandte Chemie, 2004, v. 116, n. 30, p. 4015, doi. 10.1002/ange.200460159

By:

Sabrina Buchini;
Christian J. Leumann

Publication type:

Article

DNA mit hydrophobem Basen-Ersatz: ein stabiles reißverschlussartiges Erkennungsmuster durch Interstrang-Basen-Stapelwechselwirkungen.

Published in:

Angewandte Chemie, 2003, v. 115, n. 14, p. 1694, doi. 10.1002/ange.200250516

By:

Christine Brotschi;
Christian J. Leumann

Publication type:

Article

Synthesis and Biochemical Characterization of Tricyclothymidine Triphosphate (tc-TTP).

Published in:

ChemBioChem, 2014, v. 15, n. 13, p. 1901, doi. 10.1002/cbic.201402116

By:

Hollenstein, Marcel;
Leumann, Christian J.

Publication type:

Article

Screening the Structural and Functional Properties of Bicyclo-DNA: bc<sup>ox</sup>-DNA.

Published in:

ChemBioChem, 2008, v. 9, n. 14, p. 2244, doi. 10.1002/cbic.200800322

By:

Luisier, Samuel;
Leumann, Christian J.

Publication type:

Article

RNA Abasic Sites: Preparation and Trans-Lesion Synthesis by HIV-1 Reverse Transcriptase.

Published in:

ChemBioChem, 2005, v. 6, n. 11, p. 1970, doi. 10.1002/cbic.200500204

By:

Pascal A. Küpfer;
Christian J. Leumann

Publication type:

Article

Exploring Hoogsteen and Reversed-Hoogsteen Duplex and Triplex Formation with Tricyclo-DNA Purine Sequences.

Published in:

ChemBioChem, 2004, v. 5, n. 8, p. 1114, doi. 10.1002/cbic.200400069

By:

Dorte Renneberg;
Christian J. Leumann

Publication type:

Article

An Antibody-Mediated Redox Reaction.

Published in:

Angewandte Chemie International Edition, 1988, v. 27, n. 9, p. 1172, doi. 10.1002/anie.198811721

By:

Shokat, Kevan M.;
Leumann, Christian J.;
Sugasawara, Renee;
Schultz, Peter. G.

Publication type:

Article

Pentafluorophenyl–Phenyl Interactions in Biphenyl-DNA.

Published in:

Chemistry - A European Journal, 2005, v. 11, n. 7, p. 2125, doi. 10.1002/chem.200401128

By:

Alain Zahn;
Christine Brotschi;
Christian J. Leumann

Publication type:

Article

Bipyridyl- and Biphenyl-DNA: A Recognition Motif Based on Interstrand Aromatic Stacking.

Published in:

Chemistry - A European Journal, 2005, v. 11, n. 6, p. 1911, doi. 10.1002/chem.200400858

By:

Christine Brotschi;
Gérald Mathis;
Christian J. Leumann

Publication type:

Article

Bicyclo[3.2.1]amide-DNA: A Chiral, Nonchiroselective Base-Pairing System.

Published in:

Chemistry - A European Journal, 2002, v. 8, n. 23, p. 5312, doi. 10.1002/1521-3765(20021202)8:23<5312::AID-CHEM5312>3.0.CO;2-M

By:

Ahn, Dae-Ro;
Egger, Anita;
Lehmann, Christian;
Pitsch, Stefan;
Leumann, Christian J.

Publication type:

Article

Cover Picture: Chem. Eur. J. 23/2002.

Published in:

Chemistry - A European Journal, 2002, v. 8, n. 23, p. 5275, doi. 10.1002/1521-3765(20021202)8:23<5275::AID-CHEM5275>3.0.CO;2-Z

By:

Ahn, Dae-Ro;
Egger, Anita;
Lehmann, Christian;
Pitsch, Stefan;
Leumann, Christian J.

Publication type:

Article

A Parallel Screen for the Discovery of Novel DNA Base Pairs.

Published in:

Angewandte Chemie International Edition, 2011, v. 50, n. 8, p. 1935, doi. 10.1002/anie.201005300

By:

Yaren, Oezlem;
Mosimann, Markus;
Leumann, Christian J.

Publication type:

Article

Stable Cyclohexyl-Phenyl Recognition in the Center of a DNA Duplex.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 21, p. 3810, doi. 10.1002/anie.200900153

By:

Kaufmann, Marco;
Gisler, Michael;
Leumann, Christian J.

Publication type:

Article

Strong, specific, monodentate G-C base pair recognition by N7-inosine derivatives in the pyrimidine•purine-pyrimidine triple-helical binding motif.

Published in:

Nucleic Acids Research, 1997, v. 25, n. 10, p. 1875, doi. 10.1093/nar/25.10.1875

By:

Marfurt, Judith;
Parel, Serge P.;
Leumann, Christian J.

Publication type:

Article

2-Phenanthrenyl-DNA: Synthesis, Pairing, and Fluorescence Properties.

Published in:

Chemistry - A European Journal, 2009, v. 15, n. 3, p. 639, doi. 10.1002/chem.200801135

By:

Grigorenko, Nikolay A.;
Leumann, Christian J.

Publication type:

Article

Recognition Properties of Donor- and Acceptor-Modified Biphenyl-DNA.

Published in:

Chemistry - A European Journal, 2008, v. 14, n. 4, p. 1087, doi. 10.1002/chem.200701345

By:

Zahn, Alain;
Leumann, Christian J.

Publication type:

Article

Solution Structure of a DNA Duplex Containing a Biphenyl Pair.

Published in:

Chemistry - A European Journal, 2008, v. 14, n. 4, p. 1080, doi. 10.1002/chem.200701304

By:

Johar, Zeena;
Zahn, Alain;
Leumann, Christian J.;
Jaun, Bernhard

Publication type:

Article

Synthesis and Pairing Properties of α-Tricyclo-DNA.

Published in:

Chemistry - A European Journal, 2006, v. 12, n. 31, p. 8014, doi. 10.1002/chem.200600597

By:

Scheidegger, Simon P.;
Leumann, Christian J.

Publication type:

Article

7′,5′-alpha-bicyclo-DNA: new chemistry for oligonucleotide exon splicing modulation therapy.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 21, p. 12089, doi. 10.1093/nar/gkab1097

By:

Evéquoz, Damien;
Verhaart, Ingrid E C;
van de Vijver, Davy;
Renner, Wolfgang;
Aartsma-Rus, Annemieke;
Leumann, Christian J

Publication type:

Article

NMR solution structure of tricyclo-DNA containing duplexes: insight into enhanced thermal stability and nuclease resistance.

Published in:

Nucleic Acids Research, 2019, v. 47, n. 9, p. 4872, doi. 10.1093/nar/gkz197

By:

Istrate, Andrei;
Johannsen, Silke;
Istrate, Alena;
Sigel, Roland K O;
Leumann, Christian J

Publication type:

Article

3CAPS - a structural AP-site analogue as a tool to investigate DNA base excision repair.

Published in:

Nucleic Acids Research, 2016, v. 44, n. 5, p. 2187, doi. 10.1093/nar/gkv1520

By:

Schuermann, David;
Scheidegger, Simon P.;
Weber, Alain R.;
Bjørås, Magnar;
Leumann, Christian J.;
Schär, Primo

Publication type:

Article

The effect of RNA base lesions on mRNA translation.

Published in:

Nucleic Acids Research, 2015, v. 43, n. 9, p. 4713, doi. 10.1093/nar/gkv377

By:

Calabretta, Alessandro;
Küpfer, Pascal A.;
Leumann, Christian J.

Publication type:

Article

TricycloDNA-modified oligo-2′-deoxyribonucleotides reduce scavenger receptor B1 mRNA in hepatic and extra-hepatic tissues—a comparative study of oligonucleotide length, design and chemistry.

Published in:

Nucleic Acids Research, 2012, v. 40, n. 13, p. 6135, doi. 10.1093/nar/gks273

By:

Murray, Sue;
Ittig, Damian;
Koller, Erich;
Berdeja, Andres;
Chappell, Alfred;
Prakash, Thazha P.;
Norrbom, Michaela;
Swayze, Eric E.;
Leumann, Christian J.;
Seth, Punit P.

Publication type:

Article

Synthesis, base pairing properties and trans-lesion synthesis by reverse transcriptases of oligoribonucleotides containing the oxidatively damaged base 5-hydroxycytidine.

Published in:

Nucleic Acids Research, 2011, v. 39, n. 21, p. 9422, doi. 10.1093/nar/gkr673

By:

Küpfer, Pascal A.;
Leumann, Christian J.

Publication type:

Article

Position-dependent effects on stability in tricyclo-DNA modified oligonucleotide duplexes.

Published in:

Nucleic Acids Research, 2011, v. 39, n. 1, p. 373, doi. 10.1093/nar/gkq733

By:

Ittig, Damian;
Gerber, Anna-Barbara;
Leumann, Christian J.

Publication type:

Article

2′β-Fluoro-Tricyclo Nucleic Acids (2′F-tc-ANA): Thermal Duplex Stability, Structural Studies, and RNase H Activation.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 43, p. 10310, doi. 10.1002/chem.201701476

By:

Istrate, Alena;
Katolik, Adam;
Istrate, Andrei;
Leumann, Christian J.

Publication type:

Article

Inside Back Cover: 2′β-Fluoro-Tricyclo Nucleic Acids (2′F-tc-ANA): Thermal Duplex Stability, Structural Studies, and RNase H Activation (Chem. Eur. J. 43/2017).

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 43, p. 10480, doi. 10.1002/chem.201702636

By:

Istrate, Alena;
Katolik, Adam;
Istrate, Andrei;
Leumann, Christian J.

Publication type:

Article

Back Cover: Probing the Backbone Topology of DNA: Synthesis and Properties of 7′,5′-Bicyclo-DNA (Chem. Eur. J. 33/2017).

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 33, p. 8100, doi. 10.1002/chem.201701263

By:

Evéquoz, Damien;
Leumann, Christian J.

Publication type:

Article

Probing the Backbone Topology of DNA: Synthesis and Properties of 7′,5′-Bicyclo-DNA.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 33, p. 7953, doi. 10.1002/chem.201700435

By:

Evéquoz, Damien;
Leumann, Christian J.

Publication type:

Article

Corrigendum: Modulation of Excess Electron Transfer through LUMO Gradients in DNA Containing Phenanthrenyl Base Surrogates.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 20, p. 4944, doi. 10.1002/chem.201701092

By:

Roethlisberger, Pascal;
Kaliginedi, Veerabhadrarao;
Leumann, Christian J.

Publication type:

Article

Modulation of Excess Electron Transfer through LUMO Gradients in DNA Containing Phenanthrenyl Base Surrogates.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 9, p. 2022, doi. 10.1002/chem.201605846

By:

Roethlisberger, Pascal;
Kaliginediand, Veerabhadrarao;
Leumann, Christian J.

Publication type:

Article

Enhancement of Excess Electron Transfer Efficiency in DNA Containing a Phenothiazine Donor and Multiple Stable Phenanthrenyl Base Pairs.

Published in:

Chemistry - A European Journal, 2013, v. 19, n. 35, p. 11518, doi. 10.1002/chem.201301983

By:

Roethlisberger, Pascal;
Wojciechowski, Filip;
Leumann, Christian J.

Publication type:

Article