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The Combination of a Novel GLUT1 Inhibitor and Cisplatin Synergistically Inhibits Breast Cancer Cell Growth By Enhancing the DNA Damaging Effect and Modulating the Akt/mTOR and MAPK Signaling Pathways.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.879748
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- Article
Antileukemic Natural Product Induced Both Apoptotic and Pyroptotic Programmed Cell Death and Differentiation Effect.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 20, p. 11239, doi. 10.3390/ijms222011239
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- Article
Discovery of Novel Agents on Spindle Assembly Checkpoint to Sensitize Vinorelbine-Induced Mitotic Cell Death against Human Non-Small Cell Lung Cancers.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 16, p. 5608, doi. 10.3390/ijms21165608
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- Article
Mechanistic Study of Triazole Based Aminodiol Derivatives in Leukemic Cells—Crosstalk between Mitochondrial Stress-Involved Apoptosis and Autophagy.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 7, p. 2470, doi. 10.3390/ijms21072470
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- Article
Reevesioside A, a Cardenolide Glycoside, Induces Anticancer Activity against Human Hormone-Refractory Prostate Cancers through Suppression of c-myc Expression and Induction of G1 Arrest of the Cell Cycle.
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- PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0087323
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- Article
Terfenadine induces anti-proliferative and apoptotic activities in human hormone-refractory prostate cancer through histamine receptor-independent Mcl-1 cleavage and Bak up-regulation.
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- Naunyn-Schmiedeberg's Archives of Pharmacology, 2014, v. 387, n. 1, p. 33, doi. 10.1007/s00210-013-0912-x
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- Article
Ascleposide, a natural cardenolide, induces anticancer signaling in human castration‐resistant prostatic cancer through Na<sup>+</sup>/K<sup>+</sup>‐ATPase internalization and tubulin acetylation.
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- Prostate, 2020, v. 80, n. 4, p. 305, doi. 10.1002/pros.23944
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- Article
Cardenolide glycosides sensitize gefitinib-induced apoptosis in non-small cell lung cancer: inhibition of Na<sup>+</sup>/K<sup>+</sup>-ATPase serving as a switch-on mechanism.
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- Naunyn-Schmiedeberg's Archives of Pharmacology, 2024, v. 397, n. 9, p. 6533, doi. 10.1007/s00210-024-03031-9
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- Article
Extract From Plectranthus amboinicus Inhibit Maturation and Release of Interleukin 1β Through Inhibition of NF-κB Nuclear Translocation and NLRP3 Inflammasome Activation.
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- Frontiers in Pharmacology, 2019, p. N.PAG, doi. 10.3389/fphar.2019.00573
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- Article
Para-Toluenesulfonamide Induces Anti-tumor Activity Through Akt-Dependent and -Independent mTOR/p70S6K Pathway: Roles of Lipid Raft and Cholesterol Contents.
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- Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.01223
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- Article
Phosphodiesterase Type 5 (PDE5) Inhibitors Sensitize Topoisomerase II Inhibitors in Killing Prostate Cancer Through PDE5-Independent Impairment of HR and NHEJ DNA Repair Systems.
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- Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2018.00681
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- Article
A novel HDAC6 inhibitor interferes microtubule dynamics and spindle assembly checkpoint and sensitizes cisplatin‐induced apoptosis in castration‐resistant prostate cancer.
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- Prostate, 2024, v. 84, n. 6, p. 605, doi. 10.1002/pros.24678
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- Article
Mechanistic study of dual‐function inhibitors targeting topoisomerase II and Rad51‐mediated DNA repair pathway against castration‐resistant prostate cancer.
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- Prostate, 2023, v. 83, n. 16, p. 1549, doi. 10.1002/pros.24613
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- Article
Autophagic Activation and Decrease of Plasma Membrane Cholesterol Contribute to Anticancer Activities in Non-Small Cell Lung Cancer.
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- Molecules, 2021, v. 26, n. 19, p. 5967, doi. 10.3390/molecules26195967
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- Article
Chalcones Display Anti-NLRP3 Inflammasome Activity in Macrophages through Inhibition of Both Priming and Activation Steps—Structure-Activity-Relationship and Mechanism Studies.
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- Molecules, 2020, v. 25, n. 24, p. 5960, doi. 10.3390/molecules25245960
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- Article
The (+)-Brevipolide H Displays Anticancer Activity against Human Castration-Resistant Prostate Cancer: The Role of Oxidative Stress and Akt/mTOR/p70S6K-Dependent Pathways in G1 Checkpoint Arrest and Apoptosis.
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- Molecules, 2020, v. 25, n. 12, p. 2929, doi. 10.3390/molecules25122929
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- Article
Doxazosin inhibits vasculogenic mimicry in human non‑small cell lung cancer through inhibition of the VEGF‑A/VE‑cadherin/mTOR/MMP pathway.
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- Oncology Letters, 2024, v. 27, n. 4, p. N.PAG, doi. 10.3892/ol.2024.14303
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- Article
Phosphodiesterase Type 5 Inhibitors Synergize Vincristine in Killing Castration-Resistant Prostate Cancer Through Amplifying Mitotic Arrest Signaling.
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- Frontiers in Oncology, 2020, v. 10, p. N.PAG, doi. 10.3389/fonc.2020.01274
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- Article