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Defective Efferocytosis in a Murine Model of Sjögren's Syndrome Is Mediated by Dysfunctional Mer Tyrosine Kinase Receptor.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 18, p. 9711, doi. 10.3390/ijms22189711
By:
- Witas, Richard;
- Rasmussen, Astrid;
- Scofield, Robert H.;
- Radfar, Lida;
- Stone, Donald U.;
- Grundahl, Kiely;
- Lewis, David;
- Sivils, Kathy L.;
- Lessard, Christopher J.;
- Farris, A. Darise;
- Nguyen, Cuong Q.
Publication type:
Article
Sjögren's Syndrome Minor Salivary Gland CD4+ Memory T Cells Associate with Glandular Disease Features and Have a Germinal Center T Follicular Helper Transcriptional Profile.
Published in:
Journal of Clinical Medicine, 2020, v. 9, n. 7, p. 2164, doi. 10.3390/jcm9072164
By:
- Joachims, Michelle L.;
- Leehan, Kerry M.;
- Dozmorov, Mikhail G.;
- Georgescu, Constantin;
- Pan, Zijian;
- Lawrence, Christina;
- Marlin, M. Caleb;
- Macwana, Susan;
- Rasmussen, Astrid;
- Radfar, Lida;
- Lewis, David M.;
- Stone, Donald U.;
- Grundahl, Kiely;
- Scofield, R. Hal;
- Lessard, Christopher J.;
- Wren, Jonathan D.;
- Thompson, Linda F.;
- Guthridge, Joel M.;
- Sivils, Kathy L.;
- Moore, Jacen S.
Publication type:
Article
Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome.
Published in:
Nature Genetics, 2013, v. 45, n. 11, p. 1284, doi. 10.1038/ng.2792
By:
- Lessard, Christopher J;
- Li, He;
- Adrianto, Indra;
- Ice, John A;
- Rasmussen, Astrid;
- Grundahl, Kiely M;
- Kelly, Jennifer A;
- Dozmorov, Mikhail G;
- Miceli-Richard, Corinne;
- Bowman, Simon;
- Lester, Sue;
- Eriksson, Per;
- Eloranta, Maija-Leena;
- Brun, Johan G;
- Gøransson, Lasse G;
- Harboe, Erna;
- Guthridge, Joel M;
- Kaufman, Kenneth M;
- Kvarnström, Marika;
- Jazebi, Helmi
Publication type:
Article
Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus.
Published in:
Nature Genetics, 2011, v. 43, n. 3, p. 253, doi. 10.1038/ng.766
By:
- Adrianto, Indra;
- Feng Wen;
- Templeton, Amanda;
- Wiley, Graham;
- King, Jarrod B.;
- Lessard, Christopher J.;
- Bates, Jared S.;
- Yanqing Hu;
- Kelly, Jennifer A.;
- Kaufman, Kenneth M.;
- Guthridge, Joel M.;
- Alarcón-Riquelme, Marta E.;
- Anaya, Juan-Manuel;
- Sang-Cheol Bae;
- So-Young Bang;
- Boackle, Susan A.;
- Brown, Elizabeth E.;
- Petri, Michelle A.;
- Gallant, Caroline;
- Ramsey-Goldman, Rosalind
Publication type:
Article
Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.
Published in:
Nature Genetics, 2008, v. 40, n. 9, p. 1059, doi. 10.1038/ng.200
By:
- Graham, Robert R.;
- Cotsapas, Chris;
- Davies, Leela;
- Hackett, Rachel;
- Lessard, Christopher J.;
- Leon, Joanlise M.;
- Burtt, Noel P.;
- Guiducci, Candace;
- Parkin, Melissa;
- Gates, Casey;
- Plenge, Robert M.;
- Behrens, Timothy W.;
- Wither, Joan E.;
- Rioux, John D.;
- Fortin, Paul R.;
- Graham, Deborah Cunninghame;
- Wong, Andrew K.;
- Vyse, Timothy J.;
- Daly, Mark J.;
- Altshuler, David
Publication type:
Article
Genome-Wide Association Study of African and European Americans Implicates Multiple Shared and Ethnic Specific Loci in Sarcoidosis Susceptibility.
Published in:
PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0043907
By:
- Adrianto, Indra;
- Lin, Chee Paul;
- Hale, Jessica J.;
- Levin, Albert M.;
- Datta, Indrani;
- Parker, Ryan;
- Adler, Adam;
- Kelly, Jennifer A.;
- Kaufman, Kenneth M.;
- Lessard, Christopher J.;
- Moser, Kathy L.;
- Kimberly, Robert P.;
- Harley, John B.;
- Iannuzzi, Michael C.;
- Rybicki, Benjamin A.;
- Montgomery, Courtney G.;
- Perry, John R. B.
Publication type:
Article
American Indians Have a Higher Risk of Sjögren's Syndrome and More Disease Activity Than European Americans and African Americans.
Published in:
2020
By:
- Scofield, R. Hal;
- Sharma, Rohan;
- Pezant, Nathan;
- Kelly, Jennifer A.;
- Radfar, Lida;
- Lewis, David M.;
- Kaufman, C. Erick;
- Cioli, Sarah;
- Harris, Judy;
- Grundahl, Kiely;
- Rhodus, Nelson L.;
- Wallace, Daniel J.;
- Weisman, Michael H.;
- Venuturupalli, Swamy;
- Brennan, Michael T.;
- Koelsch, Kristi A.;
- Lessard, Christopher J.;
- Montgomery, Courtney G.;
- Sivils, Kathy L.;
- Rasmussen, Astrid
Publication type:
journal article
Epistasis with HLA DR3 implicates the P2X7 receptor in the pathogenesis of primary Sjögren’s syndrome.
Published in:
Arthritis Research & Therapy, 2013, v. 15, n. 4, p. R71, doi. 10.1186/ar4248
By:
- Lester, Susan;
- Stokes, Leanne;
- Skarratt, Kristen K.;
- Gu, Ben J.;
- Sivils, Kathy L.;
- Lessard, Christopher J.;
- Wiley, James S.;
- Rischmueller, Maureen
Publication type:
Article
Sjögren Syndrome without Focal Lymphocytic Infiltration of the Salivary Glands.
Published in:
2020
By:
- Sharma, Rohan;
- Chaudhari, Kaustubh S.;
- Kurien, Biji T.;
- Grundahl, Kiely;
- Radfar, Lida;
- Lewis, David M.;
- Lessard, Christopher J.;
- He Li;
- Rasmussen, Astrid;
- Sivils, Kathy L.;
- Scofield, R. Hal;
- Li, He
Publication type:
journal article
Transcriptomic and Network Analysis of Minor Salivary Glands of Patients With Primary Sjögren's Syndrome.
Published in:
Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.606268
By:
- Oyelakin, Akinsola;
- Horeth, Erich;
- Song, Eun-Ah Christine;
- Min, Sangwon;
- Che, Monika;
- Marzullo, Brandon;
- Lessard, Christopher J.;
- Rasmussen, Astrid;
- Radfar, Lida;
- Scofield, R. Hal;
- Lewis, David M.;
- Stone, Donald U.;
- Grundahl, Kiely;
- De Rossi, Scott S.;
- Kurago, Zoya;
- Farris, A. Darise;
- Sivils, Kathy L.;
- Sinha, Satrajit;
- Kramer, Jill M.;
- Romano, Rose-Anne
Publication type:
Article
Previous diagnosis of Sjögren's Syndrome as rheumatoid arthritis or systemic lupus erythematosus.
Published in:
Rheumatology, 2016, v. 55, n. 7, p. 1195, doi. 10.1093/rheumatology/kew023
By:
- Rasmussen, Astrid;
- Radfar, Lida;
- Lewis, David;
- Grundahl, Kiely;
- Stone, Donald U.;
- Kaufman, C. Erick;
- Rhodus, Nelson L.;
- Segal, Barbara;
- Wallace, Daniel J.;
- Weisman, Michael H.;
- Venuturupalli, Swamy;
- Kurien, Biji T.;
- Lessard, Christopher J.;
- Sivils, Kathy L.;
- Scofield, R. Hal
Publication type:
Article
Alkaline unwinding flow cytometry assay to measure nucleotide excision repair.
Published in:
Mutagenesis, 2007, v. 22, n. 2, p. 147
By:
- Christopher J. Lessard;
- Gregory Veltri;
- Myron D. Gross
Publication type:
Article
The IRF5–TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.
Published in:
Human Molecular Genetics, 2015, v. 24, n. 2, p. 582, doi. 10.1093/hmg/ddu455
By:
- Kottyan, Leah C.;
- Zoller, Erin E.;
- Bene, Jessica;
- Lu, Xiaoming;
- Kelly, Jennifer A.;
- Rupert, Andrew M.;
- Lessard, Christopher J.;
- Vaughn, Samuel E.;
- Marion, Miranda;
- Weirauch, Matthew T.;
- Namjou, Bahram;
- Adler, Adam;
- Rasmussen, Astrid;
- Glenn, Stuart;
- Montgomery, Courtney G.;
- Hirschfield, Gideon M.;
- Xie, Gang;
- Coltescu, Catalina;
- Amos, Chris;
- Li, He
Publication type:
Article
Effect of Tobacco Smoking on The Clinical, Histopathological, and Serological Manifestations of Sjögren’s Syndrome.
Published in:
PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0170249
By:
- Stone, Donald U.;
- Fife, Dustin;
- Brown, Michael;
- Earley, Keith E.;
- Radfar, Lida;
- Kaufman, C. Erick;
- Lewis, David M.;
- Rhodus, Nelson L.;
- Segal, Barbara M.;
- Wallace, Daniel J.;
- Weisman, Michael H.;
- Venuturupalli, Swamy;
- Brennan, Michael T.;
- Lessard, Christopher J.;
- Montgomery, Courtney G.;
- Scofield, R. Hal;
- Sivils, Kathy L.;
- Rasmussen, Astrid
Publication type:
Article
Evidence of Alternative Modes of B Cell Activation Involving Acquired Fab Regions of N‐Glycosylation in Antibody‐Secreting Cells Infiltrating the Labial Salivary Glands of Patients With Sjögren’s Syndrome.
Published in:
Arthritis & Rheumatology, 2018, v. 70, n. 7, p. 1102, doi. 10.1002/art.40458
By:
- Koelsch, Kristi A.;
- Cavett, Joshua;
- Smith, Kenneth;
- Moore, Jacen S.;
- Lehoux, Sylvain D.;
- Jia, Nan;
- Mather, Tim;
- Quadri, Syed M. S.;
- Rasmussen, Astrid;
- Kaufman, C. Erick;
- Lewis, David M.;
- Radfar, Lida;
- Scordino, Teresa A.;
- Lessard, Christopher J.;
- Kurien, Biji T.;
- Cummings, Richard D.;
- James, Judith A.;
- Sivils, Kathy L.;
- Farris, A. Darise;
- Scofield, R. Hal
Publication type:
Article
Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.
Published in:
Arthritis & Rheumatology, 2016, v. 68, n. 5, p. 1197, doi. 10.1002/art.39548
By:
- Lessard, Christopher J.;
- Sajuthi, Satria;
- Zhao, Jian;
- Kim, Kwangwoo;
- Ice, John A.;
- Li, He;
- Ainsworth, Hannah;
- Rasmussen, Astrid;
- Kelly, Jennifer A.;
- Marion, Miranda;
- Bang, So‐Young;
- Bin Joo, Young;
- Choi, Jeongim;
- Lee, Hye‐Soon;
- Mo Kang, Young;
- Suh, Chang‐Hee;
- Tae Chung, Won;
- Lee, Soo‐Kon;
- Choe, Jung‐Yoon;
- Cheol Shim, Seung
Publication type:
Article
Brief Report: Patients With Primary Sjögren's Syndrome Who Are Positive for Autoantibodies to Tripartite Motif-Containing Protein 38 Show Greater Disease Severity.
Published in:
Arthritis & Rheumatology, 2016, v. 68, n. 3, p. 724, doi. 10.1002/art.39497
By:
- Wolska, Nina;
- Rybakowska, Paulina;
- Rasmussen, Astrid;
- Brown, Michael;
- Montgomery, Courtney;
- Klopocki, Arkadiusz;
- Grundahl, Kiely;
- Scofield, Robert H.;
- Radfar, Lida;
- Stone, Donald U.;
- Anaya, Juan M.;
- Ice, John A.;
- Lessard, Christopher J.;
- Lewis, David M.;
- Rhodus, Nelson L.;
- Gopalakrishnan, Rajaram;
- Huang, Andrew J. W.;
- Hughes, Pamela J.;
- Rohrer, Michael D.;
- Weisman, Michael H.
Publication type:
Article
Antibody-Secreting Cell Specificity in Labial Salivary Glands Reflects the Clinical Presentation and Serology in Patients With Sjögren's Syndrome.
Published in:
2014
By:
- Maier-Moore, Jacen S.;
- Koelsch, Kristi A.;
- Smith, Kenneth;
- Lessard, Christopher J.;
- Radfar, Lida;
- Lewis, David;
- Kurien, Biji T.;
- Wolska, Nina;
- Deshmukh, Umesh;
- Rasmussen, Astrid;
- Sivils, Kathy L.;
- James, Judith A.;
- Farris, A. Darise;
- Scofield, R. Hal
Publication type:
Journal Article
Antibody-Secreting Cell Specificity in Labial Salivary Glands Reflects the Clinical Presentation and Serology in Patients With Sjögren's Syndrome.
Published in:
Arthritis & Rheumatology, 2014, v. 66, n. 12, p. 3445, doi. 10.1002/art.38872
By:
- Maier‐Moore, Jacen S.;
- Koelsch, Kristi A.;
- Smith, Kenneth;
- Lessard, Christopher J.;
- Radfar, Lida;
- Lewis, David;
- Kurien, Biji T.;
- Wolska, Nina;
- Deshmukh, Umesh;
- Rasmussen, Astrid;
- Sivils, Kathy L.;
- James, Judith A.;
- Farris, A. Darise;
- Scofield, R. Hal
Publication type:
Article
Ancestral origins are associated with SARS-CoV-2 susceptibility and protection in a Florida patient population.
Published in:
PLoS ONE, 2023, v. 17, n. 1, p. 1, doi. 10.1371/journal.pone.0276700
By:
- Shen, Yiran;
- Khatri, Bhuwan;
- Rananaware, Santosh;
- Li, Danmeng;
- Ostrov, David A.;
- Jain, Piyush K.;
- Lessard, Christopher J.;
- Nguyen, Cuong Q.
Publication type:
Article
Variability of Primary Sjögren's Syndrome Is Driven by Interferon‐α and Interferon‐α Blood Levels Are Associated With the Class II HLA–DQ Locus.
Published in:
Arthritis & Rheumatology, 2022, v. 74, n. 12, p. 1991, doi. 10.1002/art.42265
By:
- Trutschel, Diana;
- Bost, Pierre;
- Mariette, Xavier;
- Bondet, Vincent;
- Llibre, Alba;
- Posseme, Celine;
- Charbit, Bruno;
- Thorball, Christian W.;
- Jonsson, Roland;
- Lessard, Christopher J.;
- Felten, Renaud;
- Ng, Wan Fai;
- Chatenoud, Lucienne;
- Dumortier, Hélène;
- Sibilia, Jean;
- Fellay, Jacques;
- Brokstad, Karl A.;
- Appel, Silke;
- Tarn, Jessica R.;
- Quintana‐Murci, Lluis
Publication type:
Article
Interferons in Sjögren's syndrome: genes, mechanisms, and effects.
Published in:
Frontiers in Immunology, 2013, v. 4, p. 1, doi. 10.3389/fimmu.2013.00290
By:
- He Li;
- Ice, John A.;
- Lessard, Christopher J.;
- Sivils, Kathy L.
Publication type:
Article
Transcriptomics and proteomics reveal a cooperation between interferon and T-helper 17 cells in neuromyelitis optica.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16625-7
By:
- Agasing, Agnieshka M.;
- Wu, Qi;
- Khatri, Bhuwan;
- Borisow, Nadja;
- Ruprecht, Klemens;
- Brandt, Alexander Ulrich;
- Gawde, Saurabh;
- Kumar, Gaurav;
- Quinn, James L.;
- Ko, Rose M.;
- Mao-Draayer, Yang;
- Lessard, Christopher J.;
- Paul, Friedemann;
- Axtell, Robert C.
Publication type:
Article

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