Works matching AU Lesch, K. P.

Results: 66

Impulsivity, aggression, and serotonin: a molecular psychobiological perspective.

Published in:

2000

By:

Lesch, Klaus Peter;
Merschdorf, Ursula;
Lesch, K P;
Merschdorf, U

Publication type:

journal article

No association between peripheral serotonin-gene-related DNA methylation and brain serotonin neurotransmission in the healthy and depressed state.

Published in:

Clinical Epigenetics, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13148-024-01678-y

By:

Bruzzone, S. E. P.;
Ozenne, B.;
Fisher, P. M.;
Ortega, G.;
Jensen, P. S.;
Dam, V. H.;
Svarer, C.;
Knudsen, G. M.;
Lesch, K. P.;
Frokjaer, V. G.

Publication type:

Article

The functional MAOA-uVNTR promoter polymorphism in patients with frontotemporal dementia.

Published in:

European Journal of Neurology, 2008, v. 15, n. 6, p. 637, doi. 10.1111/j.1468-1331.2008.02142.x

By:

Reif, A.;
Scarpini, E.;
Venturelli, E.;
Töpner, T.;
Fenoglio, C.;
Lesch, K.-P.;
Galimberti, D.

Publication type:

Article

A functional dopamine-β-hydroxylase gene promoter polymorphism is associated with impulsive personality styles, but not with affective disorders.

Published in:

Journal of Neural Transmission, 2009, v. 116, n. 2, p. 121, doi. 10.1007/s00702-008-0138-0

By:

Hess, C.;
Reif, A.;
Strobel, A.;
Boreatti-Hümmer, A.;
Heine, M.;
Lesch, K.-P.;
Jacob, C. P.

Publication type:

Article

Allelic variants of SNAP25 in a family-based sample of ADHD.

Published in:

Journal of Neural Transmission, 2008, v. 115, n. 2, p. 317, doi. 10.1007/s00702-007-0840-3

By:

Renner, T. J.;
Walitza, S.;
Dempfle, A.;
Eckert, L.;
Romanos, M.;
Gerlach, M.;
Schäfer, H.;
Warnke, A.;
Lesch, K. P.;
Jacob, C.

Publication type:

Article

Functional polymorphisms of the 5-HT1A and 5-HT1B receptor are associated with clinical symptoms in migraineurs.

Published in:

Journal of Neural Transmission, 2007, v. 114, n. 9, p. 1227, doi. 10.1007/s00702-007-0713-9

By:

Marziniak, M.;
Mössner, R.;
Kienzler, C.;
Riederer, P.;
Lesch, K.-P.;
Sommer, C.

Publication type:

Article

Adult neurogenesis in serotonin transporter deficient mice.

Published in:

Journal of Neural Transmission, 2007, v. 114, n. 9, p. 1107, doi. 10.1007/s00702-007-0724-6

By:

Schmitt, A.;
Benninghoff, J.;
Moessner, R.;
Rizzi, M.;
Paizanis, E.;
Doenitz, C.;
Gross, S.;
Hermann, M.;
Gritti, A.;
Lanfumey, L.;
Fritzen, S.;
Reif, A.;
Hamon, M.;
Murphy, D. L.;
Vescovi, A.;
Lesch, K.-P.

Publication type:

Article

No evidence for preferential transmission of common valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor gene ( BDNF) in ADHD.

Published in:

Journal of Neural Transmission, 2007, v. 114, n. 4, p. 523, doi. 10.1007/s00702-006-0616-1

By:

Schimmelmann, B. G.;
Friedel, S.;
Dempfle, A.;
Warnke, A.;
Lesch, K. P.;
Walitza, S.;
Renner, T. J.;
Romanos, M.;
Herpertz-Dahlmann, B.;
Linder, M.;
Schäfer, H.;
Seitz, C.;
Palmason, H.;
Freitag, C.;
Meyer, J.;
Konrad, K.;
Hinney, A.;
Hebebrand, J.

Publication type:

Article

Amygdala responsiveness is modulated by tryptophan hydroxylase-2 gene variation.

Published in:

Journal of Neural Transmission, 2005, v. 112, n. 11, p. 1479, doi. 10.1007/s00702-005-0391-4

By:

Canli, T.;
Congdon, E.;
Gutknecht, L.;
Constable, R. T.;
Lesch, K. P.

Publication type:

Article

Neurobiologie des Aufmerksamkeitsdefizit-/Hyperaktivitätssyndroms.

Published in:

Der Nervenarzt, 2008, v. 79, n. 7, p. 771, doi. 10.1007/s00115-008-2513-3

By:

T.J. Renner;
M. Gerlach;
M. Romanos;
M. Herrmann;
A. Reif;
A.J. Fallgatter;
K.-P. Lesch

Publication type:

Article

Emotional-motivational deficits in ADHD subtypes.

Published in:

European Child & Adolescent Psychiatry, 2010, v. 19, p. S84, doi. 10.1007/s00787-010-0117-5

By:

Conzelmann, A.;
Mucha, R. F.;
Jacob, C. P.;
Weyers, P.;
Warnke, A.;
Fallgatter, A. J.;
Lesch, K. -P.;
Pauli, P.

Publication type:

Article

Emotional-motivational deficits in ADHD subtypes.

Published in:

European Child & Adolescent Psychiatry, 2010, v. 19, p. S79, doi. 10.1007/s00787-010-0117-5

By:

Conzelmann, A.;
Mucha, R. F.;
Jacob, C. P.;
Weyers, P.;
Warnke, A.;
Fallgatter, A. J.;
Lesch, K. -P.;
Pauli, P.

Publication type:

Article

Genetic variants of KCNJ6 influence activation of the anterior cingulate cortex in ADHD but not in healthy probands.

Published in:

European Child & Adolescent Psychiatry, 2010, v. 19, p. S47, doi. 10.1007/s00787-010-0117-5

By:

Renner, T. J.;
Ehlis, A. C.;
Röser, C.;
Jacob, C.;
Gerlach, M.;
Warnke, A.;
Lesch, K. P.;
Fallgatter, A. J.

Publication type:

Article

Increased fear learning, spatial learning as well as neophobia in Rgs2−/− mice.

Published in:

Genes, Brain & Behavior, 2018, v. 17, n. 4, p. 1, doi. 10.1111/gbb.12420

By:

Raab, A.;
Popp, S.;
Lesch, K.‐P.;
Lohse, M. J.;
Fischer, M.;
Deckert, J.;
Hommers, L.

Publication type:

Article

An international multicenter association study of the serotonin transporter gene in persistent ADHD.

Published in:

Genes, Brain & Behavior, 2010, v. 9, n. 5, p. 449, doi. 10.1111/j.1601-183X.2010.00567.x

By:

Landaas, E. T.;
Johansson, S.;
Jacobsen, K. K.;
Ribasés, M.;
Bosch, R.;
Sánchez-Mora, C.;
Jacob, C. P.;
Boreatti-Hümmer, A.;
Kreiker, S.;
Lesch, K.-P.;
Kiemeney, L. A.;
Kooij, J. J. S.;
Kan, C.;
Buitelaar, J. K.;
Faraone, S. V.;
Halmøy, A.;
Ramos-Quiroga, J. A.;
Cormand, B.;
Reif, A.;
Franke, B.

Publication type:

Article

Structural variation of the monoamine oxidase A gene promoter repeat polymorphism in nonhuman primates.

Published in:

Genes, Brain & Behavior, 2006, v. 5, n. 1, p. 40, doi. 10.1111/j.1601-183X.2005.00130.x

By:

Wendland, J. R.;
Hampe, M.;
Newman, T. K.;
Syagailo, Y.;
Meyer, J.;
Schempp, W.;
Timme, A.;
Suomi, S. J.;
Lesch, K. P.

Publication type:

Article

Review Experimental gene interaction studies with SERT mutant mice as models for human polygenic and epistatic traits and disorders.

Published in:

Genes, Brain & Behavior, 2003, v. 2, n. 6, p. 350, doi. 10.1046/j.1601-1848.2003.00049.x

By:

Murphy, D. L.;
Uhl, G. R.;
Holmes, A.;
Ren-Patterson, R.;
Hall, F. S.;
Sora, I.;
Detera-Wadleigh, S.;
Lesch, K.-P.

Publication type:

Article

Commentary The utility of the non-human primate model for studying gene by environment interactions in behavioral research.

Published in:

Genes, Brain & Behavior, 2003, v. 2, n. 6, p. 336, doi. 10.1046/j.1601-1848.2003.00051.x

By:

Barr, C. S.;
Newman, T. K.;
Becker, M. L.;
Parker, C. C.;
Champoux, M.;
Lesch, K. P.;
Goldman, D.;
Suomi, S. J.;
Higley, J. D.

Publication type:

Article

Dopamine D4 receptor gene variation impacts self-reported altruism.

Published in:

Molecular Psychiatry, 2013, v. 18, n. 4, p. 402, doi. 10.1038/mp.2012.49

By:

Anacker, K;
Enge, S;
Reif, A;
Lesch, K-P;
Strobel, A

Publication type:

Article

The genetics of attention deficit/hyperactivity disorder in adults, a review.

Published in:

Molecular Psychiatry, 2012, v. 17, n. 10, p. 960, doi. 10.1038/mp.2011.138

By:

Franke, B;
Faraone, S V;
Asherson, P;
Buitelaar, J;
Bau, C H D;
Ramos-Quiroga, J A;
Mick, E;
Grevet, E H;
Johansson, S;
Haavik, J;
Lesch, K-P;
Cormand, B;
Reif, A

Publication type:

Article

The ADHD-susceptibility gene lphn3.1 modulates dopaminergic neuron formation and locomotor activity during zebrafish development.

Published in:

Molecular Psychiatry, 2012, v. 17, n. 9, p. 946, doi. 10.1038/mp.2012.29

By:

Lange, M;
Norton, W;
Coolen, M;
Chaminade, M;
Merker, S;
Proft, F;
Schmitt, A;
Vernier, P;
Lesch, K-P;
Bally-Cuif, L

Publication type:

Article

The ADHD-linked gene Lphn3.1 controls locomotor activity and impulsivity in zebrafish.

Published in:

Molecular Psychiatry, 2012, v. 17, n. 9, p. 855, doi. 10.1038/mp.2012.119

By:

Lange, M;
Norton, W;
Coolen, M;
Chaminade, M;
Merker, S;
Proft, F;
Schmitt, A;
Vernier, P;
Lesch, K-P;
Bally-Cuif, L

Publication type:

Article

Epigenetic regulation of the BDNF gene: implications for psychiatric disorders.

Published in:

Molecular Psychiatry, 2012, v. 17, n. 6, p. 584, doi. 10.1038/mp.2011.107

By:

Boulle, F;
van den Hove, D L A;
Jakob, S B;
Rutten, B P;
Hamon, M;
van Os, J;
Lesch, K-P;
Lanfumey, L;
Steinbusch, H W;
Kenis, G

Publication type:

Article

Genome-wide copy number variation analysis in attention-deficit/hyperactivity disorder: association with neuropeptide Y gene dosage in an extended pedigree.

Published in:

Molecular Psychiatry, 2011, v. 16, n. 5, p. 491, doi. 10.1038/mp.2010.29

By:

Lesch, K.-P.;
Selch, S.;
Renner, T. J.;
Jacob, C.;
Nguyen, T. T.;
Hahn, T.;
Romanos, M.;
Walitza, S.;
Shoichet, S.;
Dempfle, A.;
Heine, M.;
Boreatti-Hümmer, A.;
Romanos, J.;
Gross-Lesch, S.;
Zerlaut, H.;
Wultsch, T.;
Heinzel, S.;
Fassnacht, M.;
Fallgatter, A.;
Allolio, B.

Publication type:

Article

Tph2 gene variants modulate response control processes in adult ADHD patients and healthy individuals.

Published in:

Molecular Psychiatry, 2009, v. 14, n. 11, p. 1032, doi. 10.1038/mp.2008.39

By:

Baehne, C. G.;
Ehlis, A.-C.;
Plichta, M. M.;
Conzelmann, A.;
Pauli, P.;
Jacob, C.;
Gutknecht, L.;
Lesch, K.-P.;
Fallgatter, A. J.

Publication type:

Article

Association and linkage of allelic variants of the dopamine transporter gene in ADHD.

Published in:

Molecular Psychiatry, 2007, v. 12, n. 10, p. 923, doi. 10.1038/sj.mp.4001986

By:

Friedel, S.;
Saar, K.;
Sauer, S.;
Dempfle, A.;
Walitza, S.;
Renner, T.;
Romanos, M.;
Freitag, C.;
Seitz, C.;
Palmason, H.;
Scherag, A.;
Windemuth-Kieselbach, C.;
Schimmelmann, B. G.;
Wewetzer, C.;
Meyer, J.;
Warnke, A.;
Lesch, K. P.;
Reinhardt, R.;
Herpertz-Dahlmann, B.;
Linder, M.

Publication type:

Article

Serotonin transporter gene variation impacts innate fear processing: acoustic startle response and emotional startle.

Published in:

Molecular Psychiatry, 2006, v. 11, n. 12, p. 1106, doi. 10.1038/sj.mp.4001908

By:

Brocke, B.;
Armbruster, D.;
Müller, J.;
Hensch, T.;
Jacob, C. P.;
Lesch, K.-P.;
Kirschbaum, C.;
Strobel, A.

Publication type:

Article

Neural stem cell proliferation is decreased in schizophrenia, but not in depression.

Published in:

Molecular Psychiatry, 2006, v. 11, n. 5, p. 514, doi. 10.1038/sj.mp.4001791

By:

Reif, A;
Fritzen, S;
Finger, M;
Strobel, A;
Lauer, M;
Schmitt, A;
Lesch, K-P

Publication type:

Article

A neuronal nitric oxide synthase (NOS-I) haplotype associated with schizophrenia modifies prefrontal cortex function.

Published in:

Molecular Psychiatry, 2006, v. 11, n. 3, p. 286, doi. 10.1038/sj.mp.4001779

By:

Reif, A.;
Herterich, S.;
Strobel, A.;
Ehlis, A. -C.;
Saur, D.;
Jacob, C. P.;
Wienker, T.;
Töpner, T.;
Fritzen, S.;
Walter, U.;
Schmitt, A.;
Fallgatter, A. J.;
Lesch, K. -P.

Publication type:

Article

Simultaneous genotyping of four functional loci of human SLC6A4, with a reappraisal of 5-HTTLPR and rs25531.

Published in:

2006

By:

Wendland, J. R.;
Martin, B. J.;
Kruse, M. R.;
Lesch, K. -P.;
Murphy, D. L.

Publication type:

Letter

Transmission disequilibrium of polymorphic variants in the tryptophan hydroxylase-2 gene in attention-deficit/hyperactivity disorder.

Published in:

Molecular Psychiatry, 2005, v. 10, n. 12, p. 1126, doi. 10.1038/sj.mp.4001734

By:

Walitza, S.;
Renner, T. J.;
Dempfle, A.;
Konrad, K.;
Wewetzer, Ch.;
Halbach, A.;
Herpertz-Dahlmann, B.;
Remschmidt, H.;
Smidt, J.;
Linder, M.;
Flierl, L.;
Knölker, U.;
Friedel, S.;
Schäfer, H.;
Gross, C.;
Hebebrand, J.;
Warnke, A.;
Lesch, K. P.

Publication type:

Article

A second large family with catatonic schizophrenia supports the region distally of CHRNA7 on chromosome 15q14-15.

Published in:

Molecular Psychiatry, 2003, v. 8, n. 3, p. 259, doi. 10.1038/sj.mp.4001222

By:

Meyer, J;
Ruschendorf, F;
Lesch, K P

Publication type:

Article

Further evidence for a modulation of Novelty Seeking by DRD4 exon III, 5-HTTLPR, and COMT val/met variants.

Published in:

Molecular Psychiatry, 2003, v. 8, n. 4, p. 371, doi. 10.1038/sj.mp.4001253

By:

Strobel, A;
Lesch, K P;
Jatzke, S;
Paetzold, F;
Brocke, B

Publication type:

Article

Psychotropic Effects of Corticotropin-Releasing Hormone Stimulation in Depressive Patients.

Published in:

Neuropsychobiology, 1988, v. 19, n. 1, p. 40, doi. 10.1159/000118431

By:

Laux, G.;
Lesch, K.-P.;
Schwab, M.

Publication type:

Article

β/A4 domain of APP: Antigenic differences between cell lines.

Published in:

Journal of Neuroscience Research, 1992, v. 33, n. 2, p. 189, doi. 10.1002/jnr.490330202

By:

Wolozin, B.;
Zheng, B.;
Loren, D.;
Lesch, K. P.;
Lebovics, R. S.;
Lieberburg, I.;
Sunderland, T.

Publication type:

Article

Differential expression of carboxyl terminal derivatives of amyloid precursor protein among cell lines.

Published in:

Journal of Neuroscience Research, 1992, v. 33, n. 1, p. 163, doi. 10.1002/jnr.490330121

By:

Wolozin, B.;
Bacic, M.;
Merrill, M. J.;
Lesch, K. P.;
Chen, C.;
Lebovics, R. S.;
Sunderland, T.

Publication type:

Article

In Memoriam: Dennis L. Murphy, MD - Neuropsychopharmacologist, Scientifc Mentor, and Friend.

Published in:

2018

By:

Lesch, K P

Publication type:

Obituary

Serotonin deficiency induced after brain maturation rescues consequences of early life adversity.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-83592-4

By:

Aboagye, B.;
Weber, T.;
Merdian, H. L.;
Bartsch, D.;
Lesch, K. P.;
Waider, J.

Publication type:

Article

Altered expression and functions of serotonin 5-HT1A and 5-HT1B receptors in knock-out mice lacking the 5-HT transporter.

Published in:

European Journal of Neuroscience, 2000, v. 12, n. 7, p. 2299, doi. 10.1046/j.1460-9568.2000.00126.x

By:

Fabre, V.;
Beaufour, C.;
Evrard, A.;
Rioux, A.;
Hanoun, N.;
Lesch, K. P.;
Murphy, D. L.;
Lanfumey, L.;
Hamon, M.;
Martres, M. ‐P.

Publication type:

Article

Glucocorticoid-regulated human serotonin transporter (5-HTT) expression is modulated by the 5-HTT gene-promotor-linked polymorphic region.

Published in:

Journal of Neurochemistry, 2003, v. 86, n. 5, p. 1072, doi. 10.1046/j.1471-4159.2003.01944.x

By:

Glatz, K.;
Mössner, R.;
Heils, A.;
Lesch, K. P.

Publication type:

Article

An adenosine A2A receptor gene haplotype is associated with migraine with aura.

Published in:

Cephalalgia, 2007, v. 27, n. 2, p. 177, doi. 10.1111/j.1468-2982.2007.01254.x

By:

Hohoff, C.;
Marziniak, M.;
Lesch, K.-P.;
Deckert, J.;
Sommer, C.;
Mössner, R.

Publication type:

Article

Lack of the serotonin transporter in mice reduces locomotor activity and leads to gender-dependent late onset obesity.

Published in:

International Journal of Obesity, 2010, v. 34, n. 4, p. 701, doi. 10.1038/ijo.2009.289

By:

Üçeyler, N.;
Schütt, M.;
Palm, F.;
Vogel, C.;
Meier, M.;
Schmitt, A.;
Lesch, K.-P.;
Mössner, R.;
Sommer, C.

Publication type:

Article

D4 receptor gene variation modulates activation of prefrontal cortex during working memory.

Published in:

European Journal of Neuroscience, 2007, v. 26, n. 10, p. 2713, doi. 10.1111/j.1460-9568.2007.05921.x

By:

Herrmann, M.J.;
Walter, A.;
Schreppel, T.;
Ehlis, A.‐C.;
Pauli, P.;
Lesch, K.‐P.;
Fallgatter, A.J.

Publication type:

Article

Endocrine responses to growth hormone-releasing hormone, thyrotropin-releasing hormone and corticotropin-releasing hormone in depression.

Published in:

Acta Psychiatrica Scandinavica, 1989, v. 79, n. 6, p. 597, doi. 10.1111/j.1600-0447.1989.tb10308.x

By:

Lesch, K.-P.;
Müller, U.;
Rupprecht, R.;
Kruse, K.;
Schulte, H. M.

Publication type:

Article

Insulin-like growth factor I in depressed patients and controls.

Published in:

Acta Psychiatrica Scandinavica, 1988, v. 78, n. 6, p. 684, doi. 10.1111/j.1600-0447.1988.tb06404.x

By:

Lesch, K.-P.;
Rupprecht, R.;
Müller, U.;
Pfüller, H.;
Beckmann, H.

Publication type:

Article

Absence of reuptake of serotonin influences susceptibility to clinical autoimmune disease and neuroantigen-specific interferon-gamma production in mouse EAE.

Published in:

Clinical & Experimental Immunology, 2005, v. 142, n. 1, p. 39, doi. 10.1111/j.1365-2249.2005.02901.x

By:

Hofstetter, H. H.;
Mössner, R.;
Lesch, K. P.;
Linker, R. A.;
Toyka, K. V.;
Gold, R.

Publication type:

Article

The interplay of genotype and environment in the development of fear and anxiety.

Published in:

Neuroforum, 2013, v. 19, n. 3, p. 57, doi. 10.1007/s13295-013-0045-1

By:

Sachser, N.;
Lesch, K.-P.

Publication type:

Article

P-803 - Reduced neural error signaling in left inferior prefrontal cortex in adults with ADHD

Published in:

2012

By:

Vasic, N.;
Plichta, M.M.;
Wolf, R.C.;
Lesch, K.-P.;
Jakob, C.P.;
Fallgatter, A.J.;
Sosic-Vasic, Z.;
Grön, G.

Publication type:

Abstract

CS06-02 - Genetic underpinning of resilience

Published in:

2012

By:

Lesch, K.-P.

Publication type:

Abstract

Serotonergic modulation of 'waiting impulsivity' is mediated by the impulsivity phenotype in humans.

Published in:

Translational Psychiatry, 2016, v. 6, n. 11, p. e940, doi. 10.1038/tp.2016.210

By:

Neufang, S;
Akhrif, A;
Herrmann, C G;
Drepper, C;
Homola, G A;
Nowak, J;
Waider, J;
Schmitt, A G;
Lesch, K-P;
Romanos, M

Publication type:

Article